iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-003118

Ensembl Protein ID

ERM97781

UniProt Accession

W1NNY2; W1NNY2_AMBTC

Genbank Protein ID

ERM97781.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

KI395851

Gene Name

AMTR_s00116p00101320

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00116p00101320	ERM97781	ERM97781

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	35.64	1.00e-39	160.00	IUUC-Dme-031755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Amborella trichopoda

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MACGNPYLEE LQGSPEVVDP HTKVDKLEVN KLFNDSPQVA SKPIVTAPSS VRELLECPVC 60
LNAMYPPIHQ CSNGHTLCSG CKPRVHNRCP TCRHELGNIR CLALEKVASS LELPCKYQSF 120

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Nucleotide Sequence
(Fasta)

ATGGCTTGTG GAAATCCTTA TCTAGAGGAA TTGCAAGGAT CCCCCGAAGT TGTCGATCCT 60
CACACGAAAG TTGATAAGCT TGAAGTGAAT AAGCTTTTCA ATGATTCTCC TCAAGTTGCT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR001370--BIR_rpt
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

atr:18425767

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	72.80	7.00e-120	422.00
IUUC-Aly-006522	Arabidopsis lyrata	81.82	4.00e-133	466.00
IUUC-Ath-007092	Arabidopsis thaliana	82.82	1.00e-134	471.00
IUUC-Bdi-014729	Brachypodium distachyon	84.41	2.00e-137	480.00
IUUC-Bol-015523	Brassica oleracea	81.71	3.00e-130	456.00
IUUC-Bra-017336	Brassica rapa	82.06	4.00e-133	466.00
IUUC-Cel-018320	Caenorhabditis elegans	33.46	5.00e-38	150.00
IUUC-Dme-031755	Drosophila melanogaster	35.64	5.00e-41	160.00
IUUC-Gma-042926	Glycine max	83.28	9.00e-155	538.00
IUUC-Hvu-047574	Hordeum vulgare	68.99	6.00e-120	422.00
IUUC-Lpe-050879	Leersia perrieri	77.08	2.00e-122	431.00
IUUC-Mtr-058422	Medicago truncatula	81.31	5.00e-152	528.00
IUUC-Mac-065670	Musa acuminata	83.90	1.00e-137	481.00
IUUC-Opr-070341	Ochotona princeps	26.51	7.00e-13	66.20
IUUC-Oan-073701	Ornithorhynchus anatinus	23.49	8.00e-12	62.80
IUUC-Oba-075789	Oryza barthii	83.79	4.00e-150	522.00
IUUC-Obr-076037	Oryza brachyantha	81.94	9.00e-150	521.00
IUUC-Ogl-077148	Oryza glaberrima	83.79	4.00e-150	522.00
IUUC-Ogu-078042	Oryza glumaepatula	83.79	2.00e-150	523.00
IUUC-Oin-079325	Oryza indica	83.79	4.00e-150	522.00
IUUC-Olo-080244	Oryza longistaminata	83.79	2.00e-150	524.00
IUUC-Ome-081318	Oryza meridionalis	77.47	2.00e-122	430.00
IUUC-Oni-082163	Oryza nivara	83.79	4.00e-150	522.00
IUUC-Opu-084065	Oryza punctata	77.08	5.00e-122	429.00
IUUC-Oru-084833	Oryza rufipogon	83.79	4.00e-150	522.00
IUUC-Osa-085316	Oryza sativa	83.79	4.00e-150	522.00
IUUC-Oga-088114	Otolemur garnettii	36.19	2.00e-42	164.00
IUUC-Ppa-095212	Physcomitrella patens	86.52	1.00e-141	494.00
IUUC-Pop-100033	Populus trichocarpa	84.85	5.00e-136	475.00
IUUC-Ppe-101960	Prunus persica	85.61	3.00e-138	483.00
IUUC-Pva-103132	Pteropus vampyrus	23.31	4.00e-11	60.50
IUUC-Smo-109412	Selaginella moellendorffii	75.56	7.00e-141	491.00
IUUC-Sit-110245	Setaria italica	84.48	1.00e-149	521.00
IUUC-Sly-111259	Solanum lycopersicum	82.38	8.00e-133	465.00
IUUC-Stu-112474	Solanum tuberosum	82.95	2.00e-155	540.00
IUUC-Sbi-114035	Sorghum bicolor	84.83	8.00e-151	525.00
IUUC-Tca-121228	Theobroma cacao	85.25	1.00e-159	554.00
IUUC-Tae-123647	Triticum aestivum	72.80	7.00e-120	422.00
IUUC-Tur-126259	Triticum urartu	84.48	1.00e-148	517.00
IUUC-Vvi-131233	Vitis vinifera	73.18	1.00e-133	468.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence