iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001924

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01092356

Gene Name

UBE2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000012547.1	ENSAMET00000013777.1	ENSAMEP00000013220.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.70e-44	149.9	34	169

Active Site

Position(s)	Description	Evidence
114	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++el++l+ +  +gisa p+++ +l++w  +i G ++t+Ye+  +kl++efp+ YP+++P+vkflt+++hPnv+++G++Cl+ilk  
   Q: 34   RLQQELMTLMMSGDKGISAFPESD-NLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILK-- 119
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsll..aepnpesplneeaaellkknreeykkkvr 138
           +kWs+ ++v+++llsiqsll   epn++spln++aael+k+   ++kk v+
   Q: 120  DKWSALYDVRTILLSIQSLLgaIEPNIDSPLNTHAAELWKNPT-AFKKYVQ 169
           ********************8888*************997655.5999987 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MASQNRDPAA ASVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI SAFPESDNLF 60
KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCTCCC AGAACCGCGA CCCCGCCGCC GCCAGCGTTG CCGCCGCCCG CAAGGGAGCC 60
GAGCCCAGCG GGGGTGCCGC TCGGGGCCCC GTGGGCAAGA GGAGAGGGGG GCCCGGCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0010458--P:exit from mitosis
GO:0010994--P:free ubiquitin chain polymerization
GO:0031536--P:positive regulation of exit from mitosis
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002885	Amborella trichopoda	63.58	1.00e-51	195.00
IUUC-Aly-006086	Arabidopsis lyrata	60.26	6.00e-51	192.00
IUUC-Ath-006897	Arabidopsis thaliana	59.62	1.00e-50	192.00
IUUC-Acl-008223	Aspergillus clavatus	62.14	5.00e-38	150.00
IUUC-Afl-008675	Aspergillus flavus	61.43	4.00e-37	147.00
IUUC-Afu-008997	Aspergillus fumigatus	61.43	7.00e-37	146.00
IUUC-Ani-009470	Aspergillus nidulans	55.36	6.00e-37	146.00
IUUC-Ang-009648	Aspergillus niger	61.43	4.00e-37	147.00
IUUC-Aor-009977	Aspergillus oryzae	61.48	2.00e-30	124.00
IUUC-Ate-010318	Aspergillus terreus	60.71	9.00e-37	145.00
IUUC-Ame-011302	Astyanax mexicanus	76.16	9.00e-71	258.00
IUUC-Bta-013101	Bos taurus	97.24	1.00e-97	347.00
IUUC-Bci-013787	Botrytis cinerea	56.55	7.00e-43	166.00
IUUC-Bdi-014144	Brachypodium distachyon	69.01	6.00e-56	209.00
IUUC-Bol-015613	Brassica oleracea	60.26	1.00e-51	195.00
IUUC-Bra-017562	Brassica rapa	60.26	1.00e-51	195.00
IUUC-Cfa-020588	Canis familiaris	97.79	9.00e-95	338.00
IUUC-Cpo-021384	Cavia porcellus	96.13	6.00e-97	345.00
IUUC-Csa-024047	Chlorocebus sabaeus	96.13	6.00e-100	355.00
IUUC-Cho-024330	Choloepus hoffmanni	97.48	3.00e-66	242.00
IUUC-Cin-025365	Ciona intestinalis	56.88	2.00e-31	127.00
IUUC-Csv-025933	Ciona savignyi	59.66	8.00e-56	209.00
IUUC-Cgl-026494	Colletotrichum gloeosporioides	59.60	5.00e-43	166.00
IUUC-Cme-027266	Cyanidioschyzon merolae	50.68	9.00e-36	143.00
IUUC-Dre-027375	Danio rerio	76.16	1.00e-70	258.00
IUUC-Dno-029921	Dasypus novemcinctus	93.92	1.00e-91	327.00
IUUC-Dor-030209	Dipodomys ordii	92.82	2.00e-92	330.00
IUUC-Dse-031516	Dothistroma septosporum	54.61	6.00e-37	146.00
IUUC-Dme-031942	Drosophila melanogaster	65.52	1.00e-53	201.00
IUUC-Ete-032827	Echinops telfairi	85.71	2.00e-40	156.00
IUUC-Eca-034073	Equus caballus	97.24	2.00e-94	337.00
IUUC-Eeu-034854	Erinaceus europaeus	72.93	3.00e-65	240.00
IUUC-Fca-035666	Felis catus	97.24	2.00e-94	337.00
IUUC-Fal-037652	Ficedula albicollis	85.98	4.00e-52	195.00
IUUC-Fox-037793	Fusarium oxysporum	62.32	8.00e-42	162.00
IUUC-Fso-038151	Fusarium solani	63.04	5.00e-43	166.00
IUUC-Gmo-038894	Gadus morhua	77.50	7.00e-59	219.00
IUUC-Ggr-039730	Gaeumannomyces graminis	60.00	4.00e-34	137.00
IUUC-Gga-040537	Gallus gallus	84.78	2.00e-68	250.00
IUUC-Gac-041346	Gasterosteus aculeatus	75.35	2.00e-59	221.00
IUUC-Gma-043989	Glycine max	61.54	4.00e-53	200.00
IUUC-Ggo-045594	Gorilla gorilla	96.13	1.00e-99	354.00
IUUC-Hsa-046216	Homo sapiens	95.58	2.00e-97	347.00
IUUC-Hvu-047797	Hordeum vulgare	69.12	1.00e-52	198.00
IUUC-Itr-048402	Ictidomys tridecemlineatus	97.24	2.00e-94	337.00
IUUC-Kpa-049294	Komagataella pastoris	66.67	7.00e-46	176.00
IUUC-Lch-049761	Latimeria chalumnae	69.06	6.00e-68	249.00
IUUC-Lpe-051089	Leersia perrieri	63.29	3.00e-54	204.00
IUUC-Loc-052297	Lepisosteus oculatus	76.16	1.00e-70	259.00
IUUC-Lma-053214	Leptosphaeria maculans	54.17	2.00e-41	160.00
IUUC-Laf-054468	Loxodonta africana	96.13	5.00e-99	352.00
IUUC-Mcc-055338	Macaca mulatta	95.58	6.00e-98	348.00
IUUC-Meu-056147	Macropus eugenii	91.16	8.00e-91	325.00
IUUC-Mor-057239	Magnaporthe oryzae	57.62	1.00e-40	158.00
IUUC-Mpo-057491	Magnaporthe poae	61.43	1.00e-42	165.00
IUUC-Mtr-057687	Medicago truncatula	66.90	1.00e-45	175.00
IUUC-Mla-058880	Melampsora laricipopulina	62.68	2.00e-48	184.00
IUUC-Mga-059929	Meleagris gallopavo	84.00	7.00e-47	177.00
IUUC-Mvi-060528	Microbotryum violaceum	59.44	1.00e-43	169.00
IUUC-Mmr-060747	Microcebus murinus	98.16	6.00e-84	302.00
IUUC-Mdo-062343	Monodelphis domestica	91.76	3.00e-91	326.00
IUUC-Mmu-063563	Mus musculus	95.58	1.00e-95	341.00
IUUC-Mac-064823	Musa acuminata	63.64	8.00e-52	196.00
IUUC-Mpu-065746	Mustela putorius furo	98.34	7.00e-97	345.00
IUUC-Mlu-067388	Myotis lucifugus	96.13	8.00e-95	338.00
IUUC-Nfi-068577	Neosartorya fischeri	62.86	1.00e-37	149.00
IUUC-Ncr-068803	Neurospora crassa	57.59	3.00e-37	147.00
IUUC-Opr-070902	Ochotona princeps	93.41	3.00e-92	330.00
IUUC-Ont-071672	Oreochromis niloticus	79.29	2.00e-62	231.00
IUUC-Oan-073728	Ornithorhynchus anatinus	81.18	5.00e-37	145.00
IUUC-Ocu-074566	Oryctolagus cuniculus	92.86	4.00e-89	319.00
IUUC-Oba-075538	Oryza barthii	67.67	9.00e-51	191.00
IUUC-Obr-076757	Oryza brachyantha	70.21	3.00e-35	139.00
IUUC-Ogu-078467	Oryza glumaepatula	66.22	6.00e-55	206.00
IUUC-Oin-079533	Oryza indica	66.92	3.00e-50	189.00
IUUC-Olo-080673	Oryza longistaminata	68.42	3.00e-51	193.00
IUUC-Ome-081483	Oryza meridionalis	67.61	4.00e-54	203.00
IUUC-Oni-082321	Oryza nivara	66.22	6.00e-55	206.00
IUUC-Opu-083245	Oryza punctata	66.20	7.00e-53	199.00
IUUC-Oru-084641	Oryza rufipogon	63.46	4.00e-53	200.00
IUUC-Osa-085992	Oryza sativa	66.22	6.00e-55	206.00
IUUC-Ola-086807	Oryzias latipes	71.67	5.00e-69	253.00
IUUC-Olu-087834	Ostreococcus lucimarinus	68.35	2.00e-53	200.00
IUUC-Oga-088699	Otolemur garnettii	96.15	2.00e-98	350.00
IUUC-Oar-089542	Ovis aries	98.34	9.00e-97	345.00
IUUC-Ptr-091069	Pan troglodytes	95.58	2.00e-97	347.00
IUUC-Pan-092533	Papio anubis	96.13	6.00e-100	355.00
IUUC-Psi-093581	Pelodiscus sinensis	67.47	4.00e-57	213.00
IUUC-Pma-094607	Petromyzon marinus	70.35	2.00e-66	244.00
IUUC-Pno-094829	Phaeosphaeria nodorum	58.27	1.00e-41	161.00
IUUC-Ppa-095861	Physcomitrella patens	66.20	6.00e-54	202.00
IUUC-Pfo-096836	Poecilia formosa	69.89	1.00e-64	238.00
IUUC-Pab-098707	Pongo abelii	95.58	2.00e-97	347.00
IUUC-Pop-099021	Populus trichocarpa	66.90	4.00e-53	200.00
IUUC-Pca-100661	Procavia capensis	95.58	4.00e-96	343.00
IUUC-Ppe-101289	Prunus persica	66.20	3.00e-52	197.00
IUUC-Pva-103235	Pteropus vampyrus	92.27	7.00e-86	308.00
IUUC-Pte-104292	Pyrenophora teres	58.39	3.00e-42	163.00
IUUC-Rno-105501	Rattus norvegicus	95.03	1.00e-95	341.00
IUUC-Sce-106133	Saccharomyces cerevisiae	56.08	2.00e-35	141.00
IUUC-Sha-107205	Sarcophilus harrisii	90.21	2.00e-74	271.00
IUUC-Sja-108009	Schizosaccharomyces japonicus	59.12	3.00e-48	183.00
IUUC-Spo-108136	Schizosaccharomyces pombe	54.60	3.00e-48	183.00
IUUC-Ssl-108394	Sclerotinia sclerotiorum	59.06	6.00e-43	166.00
IUUC-Smo-109459	Selaginella moellendorffii	64.49	7.00e-51	192.00
IUUC-Sit-110754	Setaria italica	66.90	3.00e-54	204.00
IUUC-Sly-111137	Solanum lycopersicum	67.14	3.00e-52	197.00
IUUC-Stu-112305	Solanum tuberosum	66.90	1.00e-52	198.00
IUUC-Sbi-114299	Sorghum bicolor	63.89	9.00e-51	192.00
IUUC-Ssc-115625	Sus scrofa	96.69	2.00e-94	337.00
IUUC-Tru-118289	Takifugu rubripes	75.00	2.00e-35	139.00
IUUC-Tni-120070	Tetraodon nigroviridis	70.68	2.00e-54	203.00
IUUC-Tca-121158	Theobroma cacao	66.90	5.00e-53	199.00
IUUC-Tre-121973	Trichoderma reesei	60.67	6.00e-43	166.00
IUUC-Tvi-122496	Trichoderma virens	60.67	7.00e-43	166.00
IUUC-Tae-123596	Triticum aestivum	66.22	3.00e-55	207.00
IUUC-Tur-126818	Triticum urartu	65.25	1.00e-41	160.00
IUUC-Tme-127044	Tuber melanosporum	64.75	2.00e-40	158.00
IUUC-Ttr-128548	Tursiops truncatus	75.69	2.00e-65	241.00
IUUC-Vda-129840	Verticillium dahliae	59.59	7.00e-42	162.00
IUUC-Vvi-131685	Vitis vinifera	64.24	5.00e-53	199.00
IUUC-Xtr-132953	Xenopus tropicalis	80.00	1.00e-80	291.00
IUUC-Xma-134093	Xiphophorus maculatus	69.89	9.00e-65	238.00
IUUC-Yli-134548	Yarrowia lipolytica	55.43	2.00e-47	181.00
IUUC-Zma-135182	Zea mays	66.20	1.00e-53	201.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence