iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aor-009921

Ensembl Protein ID

BAE58012

UniProt Accession

Q2UKA3; Q2UKA3_ASPOR

Genbank Protein ID

BAE58012.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AP007155

Gene Name

AO090003000894

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AO090003000894	BAE58012	BAE58012

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.20e-75	251.9	503	847

Active Site

Position(s)	Description	Evidence
816	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllg 102
           ++++kk l++efvgEeg+d+gG+ +e++ ll++e+++p  glf y+e+++ + + np  +    e  + F ++G+llg+a++++ +ld++l+++ +k+ll 
   Q: 503  QEEIKKGLRIEFVGEEGVDAGGLRKEWFLLLVREIFDPHHGLFIYDEDSQFC-YFNPYCF----ESSEQFFLVGVLLGLAIYNSTILDINLPPFAFKKLLA 598
           67899**************************************999976555.7799888....5678888****************************88 PP
   S: 103  k................klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegik 187
                            k++l+dl+e  p l+k l+ +++  e d+ e+ ++  f ++ + +ge+ ++ L++gG++ pVtn+N++e+v+l+v+y l + ++
   Q: 599  AapqttgpqpattrstyKCNLDDLAEYRPPLAKGLQALLDF-EGDVAET-FCYDFVAQMDRYGEVVAVPLCTGGDKRPVTNANRREFVDLYVHYLLDTAVT 697
           888888888887778888*********************99.6788887.*************************************************** PP
   S: 188  eqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggyt....edspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk 283
           +q+e f++Gf +v+  + lslF++ee+ell+ G+ e +dv +l++ ++y++ ++    e  p++qwFw+++e  + + ++++L F+Tgs+r+P+ G  +l 
   Q: 698  RQFEPFKRGFFTVCGGNALSLFRPEEIELLVRGSdEPLDVASLRAVATYDN-WSdprpEMVPVVQWFWDFFEHTQPQAQRKILSFITGSDRIPAMGATSLI 797
           **********************************999************76.441111456778************************************* PP
   S: 284  prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            r+ ++ +  + +r+P++ TCfn+L L +Y++ e+l+++L  A+ +++gF+l
   Q: 798  IRVACLGD--DSSRFPTARTCFNMLGLYRYTTREQLEQRLWGAVLNSEGFGL 847
           88888877..77**************************************98 PP

Organism

Aspergillus oryzae

Protein Sequence
(Fasta)

MVANPATSPP HHFQRRGHSR SISHPFPSPF SSRRRNKSIS KHDFLDSDDD DDEVTYLPDP 60
LSSSPRKGAP RLSPGEELTT GKCMTCNCSV RWPRNLKVFR CTECLTVNDM EPHRGSPESS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCGCAA ATCCGGCAAC CTCGCCCCCA CATCATTTTC AGCGTCGAGG ACATTCTCGT 60
TCGATTAGCC ATCCATTCCC GTCGCCATTT TCCAGCAGAA GGCGAAACAA GTCGATATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	34.92	3.00e-97	347.00
IUUC-Atr-003144	Amborella trichopoda	38.44	8.00e-84	302.00
IUUC-Apl-003589	Anas platyrhynchos	33.99	1.00e-89	322.00
IUUC-Aca-004350	Anolis carolinensis	39.87	5.00e-93	333.00
IUUC-Ago-007908	Ashbya gossypii	29.08	1.00e-98	352.00
IUUC-Acl-008288	Aspergillus clavatus	80.78	0.00e+00	1100.00
IUUC-Afl-008402	Aspergillus flavus	98.35	0.00e+00	1226.00
IUUC-Afu-008762	Aspergillus fumigatus	80.03	0.00e+00	1102.00
IUUC-Ani-009176	Aspergillus nidulans	74.63	0.00e+00	940.00
IUUC-Ang-009791	Aspergillus niger	83.46	0.00e+00	1078.00
IUUC-Ate-010295	Aspergillus terreus	82.09	0.00e+00	1098.00
IUUC-Ame-011166	Astyanax mexicanus	38.73	1.00e-84	306.00
IUUC-Bgr-011981	Blumeria graminis	62.05	0.00e+00	804.00
IUUC-Bta-012945	Bos taurus	40.31	2.00e-95	341.00
IUUC-Bci-013697	Botrytis cinerea	61.09	0.00e+00	760.00
IUUC-Cel-018150	Caenorhabditis elegans	31.68	1.00e-54	206.00
IUUC-Cja-019263	Callithrix jacchus	39.43	2.00e-92	331.00
IUUC-Cfa-020486	Canis familiaris	35.15	3.00e-98	350.00
IUUC-Cpo-021755	Cavia porcellus	35.31	1.00e-98	352.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	41.00	3.00e-58	216.00
IUUC-Csa-023814	Chlorocebus sabaeus	39.31	4.00e-82	297.00
IUUC-Cho-025059	Choloepus hoffmanni	30.86	6.00e-71	260.00
IUUC-Cin-025643	Ciona intestinalis	32.13	2.00e-70	258.00
IUUC-Csv-026282	Ciona savignyi	31.00	2.00e-63	235.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	59.31	0.00e+00	734.00
IUUC-Cme-027151	Cyanidioschyzon merolae	36.34	7.00e-75	273.00
IUUC-Dre-028551	Danio rerio	40.85	2.00e-93	335.00
IUUC-Dno-029497	Dasypus novemcinctus	40.09	5.00e-95	340.00
IUUC-Dor-030756	Dipodomys ordii	40.58	6.00e-67	247.00
IUUC-Dse-031239	Dothistroma septosporum	53.95	0.00e+00	733.00
IUUC-Dme-032035	Drosophila melanogaster	35.03	1.00e-71	262.00
IUUC-Ete-032902	Echinops telfairi	32.67	2.00e-88	318.00
IUUC-Eca-033678	Equus caballus	35.15	9.00e-99	352.00
IUUC-Eeu-035109	Erinaceus europaeus	31.57	1.00e-71	263.00
IUUC-Fca-035590	Felis catus	31.72	4.00e-100	357.00
IUUC-Fal-037123	Ficedula albicollis	33.11	6.00e-82	296.00
IUUC-Fox-037941	Fusarium oxysporum	60.20	0.00e+00	773.00
IUUC-Fso-038388	Fusarium solani	58.77	0.00e+00	783.00
IUUC-Gmo-039553	Gadus morhua	39.16	2.00e-80	291.00
IUUC-Ggr-040110	Gaeumannomyces graminis	58.95	0.00e+00	726.00
IUUC-Gga-040406	Gallus gallus	34.16	7.00e-93	333.00
IUUC-Gac-042141	Gasterosteus aculeatus	31.52	1.00e-89	322.00
IUUC-Ggo-045504	Gorilla gorilla	39.21	3.00e-92	331.00
IUUC-Hsa-045786	Homo sapiens	39.21	3.00e-92	331.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	32.07	1.00e-76	279.00
IUUC-Kpa-049152	Komagataella pastoris	31.46	4.00e-96	343.00
IUUC-Lch-049824	Latimeria chalumnae	40.10	5.00e-80	290.00
IUUC-Loc-052173	Lepisosteus oculatus	35.31	4.00e-101	360.00
IUUC-Laf-054017	Loxodonta africana	39.87	2.00e-94	337.00
IUUC-Mcc-055713	Macaca mulatta	39.43	2.00e-92	332.00
IUUC-Meu-056061	Macropus eugenii	32.66	2.00e-77	281.00
IUUC-Mor-057045	Magnaporthe oryzae	60.09	0.00e+00	764.00
IUUC-Mla-059187	Melampsora laricipopulina	41.80	1.00e-92	331.00
IUUC-Mga-059884	Meleagris gallopavo	40.00	4.00e-86	310.00
IUUC-Mmr-061344	Microcebus murinus	34.98	2.00e-99	354.00
IUUC-Mdo-062653	Monodelphis domestica	40.75	3.00e-95	341.00
IUUC-Mmu-063775	Mus musculus	40.44	6.00e-96	343.00
IUUC-Mpu-066069	Mustela putorius furo	35.15	2.00e-98	351.00
IUUC-Mlu-067925	Myotis lucifugus	40.09	2.00e-95	341.00
IUUC-Nfi-068439	Neosartorya fischeri	79.79	0.00e+00	1083.00
IUUC-Ncr-068903	Neurospora crassa	60.42	0.00e+00	723.00
IUUC-Nle-070046	Nomascus leucogenys	34.43	8.00e-95	339.00
IUUC-Opr-070570	Ochotona princeps	28.60	4.00e-60	224.00
IUUC-Ont-072126	Oreochromis niloticus	34.98	9.00e-97	345.00
IUUC-Oan-072933	Ornithorhynchus anatinus	39.51	2.00e-92	331.00
IUUC-Ocu-073800	Oryctolagus cuniculus	39.43	4.00e-92	330.00
IUUC-Ola-086988	Oryzias latipes	30.99	3.00e-93	334.00
IUUC-Oga-088117	Otolemur garnettii	39.43	3.00e-92	330.00
IUUC-Oar-089371	Ovis aries	40.31	5.00e-95	340.00
IUUC-Ptr-090551	Pan troglodytes	39.21	3.00e-92	330.00
IUUC-Pan-092067	Papio anubis	39.43	2.00e-92	331.00
IUUC-Psi-092963	Pelodiscus sinensis	39.65	9.00e-92	329.00
IUUC-Pma-094643	Petromyzon marinus	33.67	2.00e-80	291.00
IUUC-Ppa-095354	Physcomitrella patens	38.65	4.00e-86	311.00
IUUC-Pfo-096562	Poecilia formosa	31.84	3.00e-96	343.00
IUUC-Pab-098680	Pongo abelii	39.21	2.00e-92	331.00
IUUC-Pca-100869	Procavia capensis	32.55	7.00e-79	286.00
IUUC-Pva-103040	Pteropus vampyrus	40.87	4.00e-66	244.00
IUUC-Pgr-103315	Puccinia graminis	40.83	2.00e-98	352.00
IUUC-Ptt-103736	Puccinia triticina	41.60	1.00e-98	352.00
IUUC-Rno-105270	Rattus norvegicus	40.75	6.00e-97	346.00
IUUC-Sce-106306	Saccharomyces cerevisiae	28.75	3.00e-84	304.00
IUUC-Sha-106819	Sarcophilus harrisii	35.42	4.00e-99	353.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	32.68	4.00e-66	244.00
IUUC-Spo-108271	Schizosaccharomyces pombe	36.26	3.00e-114	404.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	60.88	0.00e+00	809.00
IUUC-Smo-108858	Selaginella moellendorffii	41.33	6.00e-86	310.00
IUUC-Sar-113134	Sorex araneus	35.92	8.00e-78	283.00
IUUC-Ssc-115441	Sus scrofa	40.00	1.00e-94	338.00
IUUC-Tgu-117166	Taeniopygia guttata	34.49	2.00e-90	325.00
IUUC-Tru-118368	Takifugu rubripes	37.42	5.00e-82	297.00
IUUC-Tsy-118898	Tarsius syrichta	35.51	5.00e-75	273.00
IUUC-Tni-120143	Tetraodon nigroviridis	37.64	3.00e-82	297.00
IUUC-Tre-122108	Trichoderma reesei	60.00	0.00e+00	718.00
IUUC-Tvi-122644	Trichoderma virens	60.69	0.00e+00	734.00
IUUC-Tme-127004	Tuber melanosporum	59.97	0.00e+00	755.00
IUUC-Tbe-127640	Tupaia belangeri	37.97	3.00e-67	248.00
IUUC-Ttr-128352	Tursiops truncatus	37.89	2.00e-85	308.00
IUUC-Vda-129969	Verticillium dahliae	60.81	0.00e+00	740.00
IUUC-Vpa-130448	Vicugna pacos	33.82	5.00e-72	264.00
IUUC-Xtr-132594	Xenopus tropicalis	38.29	9.00e-82	296.00
IUUC-Xma-134157	Xiphophorus maculatus	31.60	5.00e-87	313.00
IUUC-Yli-134470	Yarrowia lipolytica	35.30	5.00e-104	370.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence