iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G43990	AT5G43990.8	AT5G43990.8
AT5G43990	AT5G43990.9	AT5G43990.9
AT5G43990	AT5G43990.15	AT5G43990.15
AT5G43990	AT5G43990.7	AT5G43990.7

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/WIYLD	WIYLD	24625295

Organism

Arabidopsis thaliana

Functional Description
(View)

Probable inactive histone-lysine methyltransferase that acts as regulator of transctiptional gene silencing independently of histone H3K9 methylation. Contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. Forms a complex with SUVR1 and associates with the SNF2-related chromatin-remodeling proteins CHR19, CHR27, and CHR28, thereby mediating nucleosome positioning and transcriptional silencing. Does not possess histone-lysine methyltransferase activity in vitro, and the conserved catalytic sites of SUVR2 are dispensable for its function in transcriptional gene silencing.

Protein Sequence
(Fasta)

MRSYNLFHES NPTISFSFVG AETMAPNLHI KKAFMAMRAM GIEDARVKPV LKNLLALYEK 60
NWELIAEDNY RVLADAIFDS HEDQAIQESE EKKADEVKED EGCAAEVDRG KKKLHESIED 120

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Nucleotide Sequence
(Fasta)

AGAAAGAGAG AGGGTCAACA AAAAGTCACA GTCGAACAAG ATACTGAGAA AGAAACGAAA 60
TTTCACCTGG CACTGTCCTC GCGTGTACTC TCACGCGCCG ACGTAATACT CTGCCGTCGT 120

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Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0943--RNA-mediated gene silencing
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc

Interpro

IPR007728--Pre-SET_dom
IPR001214--SET_dom
IPR025776--SUVR4/1/2
IPR018848--WIYLD_domain

PROSITE

PS51580--SAM_MT43_3
PS50280--SET

Pfam

PF05033--Pre-SET
PF00856--SET
PF10440--WIYLD

SMART

SM00468--PreSET
SM00317--SET

Gene Ontology

GO:0005694--C:chromosome
GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0080188--P:RNA-directed DNA methylation

KEGG

ath:AT5G43990

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006180	Arabidopsis lyrata	87.50	0.00e+00	1220.00
IUUC-Acl-008029	Aspergillus clavatus	36.11	6.60e-01	28.10
IUUC-Afl-008434	Aspergillus flavus	32.50	1.30e+00	26.90
IUUC-Aor-010068	Aspergillus oryzae	32.50	1.30e+00	26.90
IUUC-Bdi-014356	Brachypodium distachyon	38.71	1.00e-127	449.00
IUUC-Bol-016555	Brassica oleracea	63.44	0.00e+00	895.00
IUUC-Bra-017733	Brassica rapa	62.18	0.00e+00	888.00
IUUC-Gma-042766	Glycine max	42.60	8.00e-134	470.00
IUUC-Kpa-049254	Komagataella pastoris	29.85	6.50e-01	28.50
IUUC-Mtr-057841	Medicago truncatula	38.89	2.00e-128	452.00
IUUC-Mac-065303	Musa acuminata	41.33	3.00e-143	501.00
IUUC-Nfi-068594	Neosartorya fischeri	35.00	6.40e-01	28.10
IUUC-Pop-099927	Populus trichocarpa	45.97	3.00e-151	528.00
IUUC-Ppe-101635	Prunus persica	40.07	1.00e-149	523.00
IUUC-Sit-109892	Setaria italica	38.14	3.00e-121	428.00
IUUC-Tca-121451	Theobroma cacao	50.53	1.00e-156	546.00
IUUC-Tre-121976	Trichoderma reesei	61.54	4.40e+00	24.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence