iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055245

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03004053

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000000070.3	ENSMMUT00000045131.2	ENSMMUP00000038148.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	97.47	0.00e+00	723.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDRSKENCIS GPVKPAAPVG GPKRVLVTQQ FPCQNPLPAN SGQAQRVLCP SNSSQRVPLQ 60
AQKLVSSHKL VQNQKQKQLQ ATSVPHPVSR PPSHTPKSKQ PLPSAPENNP EEELASKQKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCGACGAG GGCGGCGGGG ACAAGGGGCG GCCGGCCGGA GTGGCGGAGT GTCAAGTCCC 60
CTCTCGGTTC CTCCGTCCCT GGGTGTCCTT GGCGCTACCC TGTGCCCGCC CAGTGCCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

KEGG

mcc:698190

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	63.80	3.00e-103	367.00
IUUC-Aml-001426	Ailuropoda melanoleuca	91.21	0.00e+00	722.00
IUUC-Atr-002453	Amborella trichopoda	64.01	1.00e-107	382.00
IUUC-Apl-003626	Anas platyrhynchos	73.45	2.00e-155	541.00
IUUC-Aca-004602	Anolis carolinensis	67.00	2.00e-148	519.00
IUUC-Aly-005878	Arabidopsis lyrata	64.68	1.00e-104	372.00
IUUC-Ath-007117	Arabidopsis thaliana	65.43	3.00e-105	374.00
IUUC-Acl-008199	Aspergillus clavatus	57.46	1.00e-86	313.00
IUUC-Afl-008419	Aspergillus flavus	57.09	7.00e-86	310.00
IUUC-Afu-008751	Aspergillus fumigatus	53.72	2.00e-86	312.00
IUUC-Ani-009181	Aspergillus nidulans	55.36	9.00e-90	323.00
IUUC-Ang-009787	Aspergillus niger	50.30	5.00e-87	314.00
IUUC-Aor-009980	Aspergillus oryzae	57.09	7.00e-86	310.00
IUUC-Ate-010286	Aspergillus terreus	55.36	4.00e-86	311.00
IUUC-Ame-010849	Astyanax mexicanus	73.17	2.00e-127	449.00
IUUC-Bgr-012110	Blumeria graminis	59.42	8.00e-88	317.00
IUUC-Bta-013474	Bos taurus	88.66	0.00e+00	711.00
IUUC-Bci-013756	Botrytis cinerea	58.97	2.00e-93	336.00
IUUC-Bdi-014257	Brachypodium distachyon	63.60	1.00e-104	372.00
IUUC-Bol-016310	Brassica oleracea	61.25	2.00e-102	365.00
IUUC-Bra-017438	Brassica rapa	61.25	9.00e-104	369.00
IUUC-Cel-018157	Caenorhabditis elegans	61.23	7.00e-101	360.00
IUUC-Cja-019282	Callithrix jacchus	95.45	0.00e+00	750.00
IUUC-Cfa-020162	Canis familiaris	89.92	0.00e+00	715.00
IUUC-Cpo-021764	Cavia porcellus	84.13	0.00e+00	663.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	66.92	7.00e-107	380.00
IUUC-Csa-023694	Chlorocebus sabaeus	99.24	0.00e+00	718.00
IUUC-Cho-024350	Choloepus hoffmanni	96.43	1.00e-112	398.00
IUUC-Cin-025542	Ciona intestinalis	72.73	8.00e-117	412.00
IUUC-Csv-025873	Ciona savignyi	69.96	4.00e-117	414.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	48.07	6.00e-83	301.00
IUUC-Cne-026928	Cryptococcus neoformans	61.09	4.00e-94	338.00
IUUC-Cme-027336	Cyanidioschyzon merolae	62.77	7.00e-119	420.00
IUUC-Dre-028198	Danio rerio	60.91	1.00e-130	459.00
IUUC-Dno-029928	Dasypus novemcinctus	86.56	0.00e+00	642.00
IUUC-Dor-030238	Dipodomys ordii	78.99	1.00e-179	622.00
IUUC-Dse-031266	Dothistroma septosporum	54.87	1.00e-92	333.00
IUUC-Dme-032007	Drosophila melanogaster	61.83	6.00e-100	357.00
IUUC-Ete-032911	Echinops telfairi	68.07	7.00e-132	463.00
IUUC-Eca-033749	Equus caballus	91.21	0.00e+00	713.00
IUUC-Eeu-035170	Erinaceus europaeus	87.69	0.00e+00	706.00
IUUC-Fca-035498	Felis catus	91.27	0.00e+00	706.00
IUUC-Fal-037397	Ficedula albicollis	68.04	2.00e-146	511.00
IUUC-Fox-037747	Fusarium oxysporum	54.31	1.00e-91	330.00
IUUC-Fso-038429	Fusarium solani	54.19	7.00e-90	323.00
IUUC-Gmo-039378	Gadus morhua	75.09	5.00e-124	437.00
IUUC-Ggr-039939	Gaeumannomyces graminis	58.80	2.00e-95	342.00
IUUC-Gga-040187	Gallus gallus	70.66	5.00e-151	527.00
IUUC-Gac-042223	Gasterosteus aculeatus	60.57	2.00e-129	455.00
IUUC-Gma-042870	Glycine max	62.94	6.00e-99	353.00
IUUC-Ggo-045617	Gorilla gorilla	97.22	0.00e+00	798.00
IUUC-Hsa-046968	Homo sapiens	97.47	0.00e+00	801.00
IUUC-Hvu-047072	Hordeum vulgare	54.10	4.00e-81	294.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	78.23	7.00e-176	609.00
IUUC-Kpa-049093	Komagataella pastoris	55.94	2.00e-76	279.00
IUUC-Lch-050346	Latimeria chalumnae	67.51	7.00e-145	506.00
IUUC-Lpe-051466	Leersia perrieri	64.08	5.00e-105	374.00
IUUC-Lma-053006	Leptosphaeria maculans	58.94	6.00e-89	321.00
IUUC-Laf-053422	Loxodonta africana	85.89	0.00e+00	696.00
IUUC-Mor-056952	Magnaporthe oryzae	57.45	3.00e-91	328.00
IUUC-Mpo-057605	Magnaporthe poae	58.04	2.00e-96	345.00
IUUC-Mtr-057726	Medicago truncatula	64.00	1.00e-104	372.00
IUUC-Mla-059174	Melampsora laricipopulina	62.93	1.00e-97	350.00
IUUC-Mga-059562	Meleagris gallopavo	60.40	8.00e-118	417.00
IUUC-Mvi-060305	Microbotryum violaceum	61.60	3.00e-93	335.00
IUUC-Mmr-061588	Microcebus murinus	89.92	0.00e+00	735.00
IUUC-Mdo-061914	Monodelphis domestica	79.12	1.00e-177	615.00
IUUC-Mmu-063288	Mus musculus	82.82	0.00e+00	637.00
IUUC-Mac-064969	Musa acuminata	63.67	6.00e-106	376.00
IUUC-Mpu-066855	Mustela putorius furo	89.66	0.00e+00	707.00
IUUC-Mlu-068046	Myotis lucifugus	89.15	0.00e+00	700.00
IUUC-Nfi-068527	Neosartorya fischeri	57.84	2.00e-86	312.00
IUUC-Ncr-068678	Neurospora crassa	59.42	2.00e-93	335.00
IUUC-Nle-069848	Nomascus leucogenys	96.72	0.00e+00	794.00
IUUC-Opr-070589	Ochotona princeps	82.32	0.00e+00	628.00
IUUC-Ont-071733	Oreochromis niloticus	61.52	7.00e-122	430.00
IUUC-Oan-073399	Ornithorhynchus anatinus	88.69	7.00e-152	529.00
IUUC-Ocu-074063	Oryctolagus cuniculus	87.41	0.00e+00	709.00
IUUC-Oba-075264	Oryza barthii	63.67	2.00e-105	374.00
IUUC-Obr-076048	Oryza brachyantha	63.64	3.00e-104	371.00
IUUC-Ogl-077637	Oryza glaberrima	66.42	9.00e-104	369.00
IUUC-Ogu-078830	Oryza glumaepatula	63.67	2.00e-105	374.00
IUUC-Oin-079150	Oryza indica	63.67	1.00e-105	375.00
IUUC-Olo-080398	Oryza longistaminata	57.68	2.00e-82	298.00
IUUC-Ome-081544	Oryza meridionalis	54.41	3.00e-90	324.00
IUUC-Oni-082250	Oryza nivara	63.67	1.00e-105	375.00
IUUC-Opu-083638	Oryza punctata	64.01	4.00e-106	377.00
IUUC-Oru-084981	Oryza rufipogon	63.67	1.00e-105	376.00
IUUC-Osa-085961	Oryza sativa	63.67	1.00e-105	376.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.96	9.00e-112	396.00
IUUC-Oga-088891	Otolemur garnettii	89.87	0.00e+00	713.00
IUUC-Oar-090021	Ovis aries	88.41	0.00e+00	685.00
IUUC-Ptr-091458	Pan troglodytes	97.73	0.00e+00	801.00
IUUC-Pan-092546	Papio anubis	99.24	0.00e+00	721.00
IUUC-Psi-093280	Pelodiscus sinensis	75.89	4.00e-162	563.00
IUUC-Pma-094298	Petromyzon marinus	76.60	1.00e-120	425.00
IUUC-Pno-094847	Phaeosphaeria nodorum	51.67	4.00e-89	321.00
IUUC-Ppa-095855	Physcomitrella patens	65.58	9.00e-108	382.00
IUUC-Pfo-096428	Poecilia formosa	59.95	2.00e-126	445.00
IUUC-Pab-098696	Pongo abelii	96.47	0.00e+00	775.00
IUUC-Pop-099405	Populus trichocarpa	61.59	9.00e-106	376.00
IUUC-Pca-100740	Procavia capensis	80.86	0.00e+00	655.00
IUUC-Ppe-101854	Prunus persica	63.19	1.00e-106	379.00
IUUC-Pva-103212	Pteropus vampyrus	88.63	0.00e+00	694.00
IUUC-Pgr-103474	Puccinia graminis	62.88	1.00e-97	350.00
IUUC-Ptt-103933	Puccinia triticina	49.03	3.00e-61	228.00
IUUC-Pte-104089	Pyrenophora teres	47.47	6.00e-92	331.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	47.47	5.00e-92	331.00
IUUC-Rno-105057	Rattus norvegicus	83.54	0.00e+00	650.00
IUUC-Sha-107137	Sarcophilus harrisii	79.59	2.00e-178	618.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	59.93	3.00e-98	351.00
IUUC-Spo-108078	Schizosaccharomyces pombe	63.46	6.00e-101	360.00
IUUC-Smo-109288	Selaginella moellendorffii	63.67	1.00e-107	382.00
IUUC-Sit-110246	Setaria italica	63.32	7.00e-106	376.00
IUUC-Sly-111379	Solanum lycopersicum	64.73	1.00e-105	376.00
IUUC-Stu-112777	Solanum tuberosum	61.25	4.00e-106	377.00
IUUC-Sbi-114325	Sorghum bicolor	64.52	5.00e-105	373.00
IUUC-Sre-115203	Sporisorium reilianum	58.65	3.00e-80	292.00
IUUC-Ssc-115361	Sus scrofa	87.63	0.00e+00	701.00
IUUC-Tgu-116967	Taeniopygia guttata	72.24	6.00e-147	513.00
IUUC-Tru-117570	Takifugu rubripes	62.66	2.00e-138	485.00
IUUC-Tsy-119280	Tarsius syrichta	68.94	1.00e-145	509.00
IUUC-Tni-120721	Tetraodon nigroviridis	62.72	2.00e-132	465.00
IUUC-Tca-121494	Theobroma cacao	61.67	4.00e-105	374.00
IUUC-Tre-121869	Trichoderma reesei	55.00	3.00e-94	338.00
IUUC-Tvi-122510	Trichoderma virens	57.93	1.00e-92	333.00
IUUC-Tae-123071	Triticum aestivum	63.80	3.00e-103	367.00
IUUC-Tur-126240	Triticum urartu	63.80	9.00e-103	366.00
IUUC-Tme-126921	Tuber melanosporum	62.93	2.00e-95	342.00
IUUC-Tbe-127872	Tupaia belangeri	85.79	0.00e+00	641.00
IUUC-Ttr-129134	Tursiops truncatus	89.15	0.00e+00	674.00
IUUC-Uma-129412	Ustilago maydis	59.25	5.00e-79	288.00
IUUC-Vda-130003	Verticillium dahliae	51.04	2.00e-95	342.00
IUUC-Vvi-131272	Vitis vinifera	62.98	7.00e-106	376.00
IUUC-Xtr-132019	Xenopus tropicalis	64.30	4.00e-146	511.00
IUUC-Xma-134203	Xiphophorus maculatus	60.86	8.00e-132	463.00
IUUC-Yli-134503	Yarrowia lipolytica	53.85	1.00e-85	310.00
IUUC-Zma-135232	Zea mays	61.82	8.00e-106	376.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence