iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Stu-112001

Ensembl Protein ID

PGSC0003DMT400052983

UniProt Accession

M1BU82; M1BU82_SOLTU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGSC0003DMG400020558	PGSC0003DMT400052983	PGSC0003DMT400052983

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.20e-176	589.2	485	973

Active Site

Position(s)	Description	Evidence
666	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD Qi ++G++ q+kl+ akv+lvG g+lGcE+lKnL+l+Gv     g++tv+D+d +e+snl+rqFLfr++++g+ K+ vaa+a++ +
   Q: 485  YDAQISVFGQKFQKKLEDAKVFLVGSGALGCEFLKNLALMGVacteqGKLTVTDDDVIEKSNLSRQFLFRDWNIGQAKSTVAAAAATSI 573
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkt 170
           np+ +vea ++++ +++e+++   F ++++vV++aldn+ ar++v+++cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k+
   Q: 574  NPQLRVEALQNRVGPETENVFddtFWENLSVVINALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQ 662
           *******************99******************************************************************** PP
   S: 171  iPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafak 247
           +P+ctl ++p +++h+++wa            + +n +l++ ++ ++ + +   ++ ++ ++++ + l  e  e+fe++i++a+ +f++
   Q: 663  APMCTLHSFPHNIDHCLTWArsefegllektpAEVNAYLSNPSEYTSAQTNAGDAQARDNLERILECLDRESCETFEDCIAWARLKFEE 751
           *************************999999988888888888888888888889999999999999999******************* PP
   S: 248  ttinsikqllksfecdivtkskspfwv.........................................................sfcsn 279
           ++ n +kql+  f+ d vt+s++pfw+                                                          f + 
   Q: 752  YFANRVKQLIFTFPEDAVTSSGAPFWSapkrfprplqfsstdpshlhfimaasilraetfgipipdwvkhpkklseavhkvmvpCFQPR 840
           *****************************************************************999988877777777777733333 PP
   S: 280  aealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikei 361
           ++a+ v +  + +   +++ ++       + ++  +r +  +g  ++ ++fekddd   ++dl++a+an+ra ++ i++ +d+ + k i
   Q: 841  KDAKIVTDEKATSLSSSASIDDaavidELISKLECSRKNLPPGFRMKPIQFEKDDDTnyHMDLIAALANMRARNYCIPE-VDKLKAKFI 928
           333333322222222222222246743445555566677779*************************************.********* PP
   S: 362  agniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           ag+iipaiatt+a+  Gl+++E++Kv++g  k e ++n+f ++a+
   Q: 929  AGRIIPAIATTTAMATGLVCLELYKVLDGghKLEDYRNTFANLAL 973
           ****************************************99875 PP

Organism

Solanum tuberosum

Protein Sequence
(Fasta)

MLPKKRPAEG VVVEGNSSSC DPESALKKPR ISCVISSGTK ENTSGCSSNK VVSNNTNGNA 60
SSSSVGERSV TEMAFDDGNP HDIDEDLHSR QLAVYGRETM RRLFASNVLV SGIQGLGAEI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAGAGAGA TGCACGTAAT GGAAACGCTA CCCATTTTTT CTCTGTAAAC CCTCCTAAAT 60
CTCTAAACCG AGATTTTTTT TCTCTCACAC AAAATCCATA AATACCCCCT CACCTCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

sot:102604026

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	80.06	0.00e+00	1610.00
IUUC-Aly-005418	Arabidopsis lyrata	81.47	0.00e+00	1739.00
IUUC-Ath-006992	Arabidopsis thaliana	80.20	0.00e+00	1689.00
IUUC-Afl-008455	Aspergillus flavus	46.31	0.00e+00	813.00
IUUC-Ani-009371	Aspergillus nidulans	47.41	0.00e+00	823.00
IUUC-Ang-009737	Aspergillus niger	46.89	0.00e+00	823.00
IUUC-Aor-010007	Aspergillus oryzae	46.31	0.00e+00	813.00
IUUC-Bdi-014843	Brachypodium distachyon	79.73	0.00e+00	1606.00
IUUC-Bol-015880	Brassica oleracea	81.57	0.00e+00	1736.00
IUUC-Bra-017252	Brassica rapa	81.76	0.00e+00	1737.00
IUUC-Cho-024682	Choloepus hoffmanni	35.51	1.00e-99	356.00
IUUC-Eeu-035323	Erinaceus europaeus	40.65	5.00e-150	524.00
IUUC-Fso-038339	Fusarium solani	47.26	0.00e+00	832.00
IUUC-Gma-043198	Glycine max	81.77	0.00e+00	1771.00
IUUC-Hvu-047418	Hordeum vulgare	80.00	0.00e+00	1631.00
IUUC-Laf-053948	Loxodonta africana	46.34	0.00e+00	864.00
IUUC-Mtr-058572	Medicago truncatula	81.14	0.00e+00	1732.00
IUUC-Mla-059176	Melampsora laricipopulina	47.12	0.00e+00	872.00
IUUC-Mga-059721	Meleagris gallopavo	39.40	0.00e+00	646.00
IUUC-Obr-076557	Oryza brachyantha	79.68	0.00e+00	1627.00
IUUC-Oin-079370	Oryza indica	77.11	0.00e+00	1600.00
IUUC-Ome-081942	Oryza meridionalis	79.88	0.00e+00	1634.00
IUUC-Oni-082365	Oryza nivara	79.78	0.00e+00	1631.00
IUUC-Opu-083977	Oryza punctata	79.59	0.00e+00	1630.00
IUUC-Osa-085949	Oryza sativa	79.39	0.00e+00	1646.00
IUUC-Pop-098934	Populus trichocarpa	78.63	0.00e+00	1758.00
IUUC-Ppe-101298	Prunus persica	79.40	0.00e+00	1737.00
IUUC-Pgr-103336	Puccinia graminis	45.91	0.00e+00	827.00
IUUC-Ptt-103939	Puccinia triticina	46.12	0.00e+00	830.00
IUUC-Sit-110281	Setaria italica	81.19	0.00e+00	1659.00
IUUC-Sly-111237	Solanum lycopersicum	98.43	0.00e+00	1967.00
IUUC-Sre-115148	Sporisorium reilianum	46.60	0.00e+00	833.00
IUUC-Tca-121436	Theobroma cacao	79.89	0.00e+00	1783.00
IUUC-Tae-125113	Triticum aestivum	80.12	0.00e+00	1607.00
IUUC-Tur-126189	Triticum urartu	80.39	0.00e+00	1615.00
IUUC-Uma-129387	Ustilago maydis	47.08	0.00e+00	828.00
IUUC-Vvi-130857	Vitis vinifera	82.11	0.00e+00	1788.00
IUUC-Xtr-132947	Xenopus tropicalis	37.72	1.00e-177	616.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence