iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008936

Ensembl Protein ID

CADAFUAP00006265

UniProt Accession

Q4WVD0; ATG18_ASPFU

Genbank Protein ID

EAL91446.1

Protein Name

Autophagy-related protein 18

Genbank Nucleotide ID

AAHF01000003

Gene Name

AFUA_5G11660; atg18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00006265	CADAFUAT00006265	CADAFUAP00006265

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.70e-08	31.3	193	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgt.ikvWDlrtgvll 36
           H ++  c+ + sd tll+++sd gt i+v+++ +g++l
   Q: 193  HRSPLACITLnSDgTLLATASDKGTiIRVFSVPDGHKL 230
           999********999***********999****999876 PP

Organism

Aspergillus fumigatus

Functional Description
(View)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct atg9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

Protein Sequence
(Fasta)

MAMNFVTFNQ DYSYLAVGSV SPPSATSKGF RIFTTDPFAK SYETKEGNIA IIEMLFSTSL 60
VALILSPRRL QITNTKRQST ICELTFPTTV LAVRLNRKRL VIVLEDQIYL YDIQTMKLLY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAATGA ACTTCGTGAC CTTTAACCAA GACTACAGCT ACCTGGCTGT TGGTAAGCGC 60
CCCTCGGAAC TCTTCAAGCG CATGCGCACG CTCTAAGGCT CTGTATCCCC TCCATCAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0010008--C:endosome membrane
GO:0000329--C:fungal-type vacuole membrane
GO:0005794--C:Golgi apparatus
GO:0034045--C:pre-autophagosomal structure membrane
GO:0016236--P:macroautophagy
GO:0015031--P:protein transport

KEGG

afm:AFUA_5G11660

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000966	Aegilops tauschii	30.88	2.00e-46	178.00
IUUC-Aml-001842	Ailuropoda melanoleuca	44.79	3.00e-55	207.00
IUUC-Atr-002710	Amborella trichopoda	31.72	4.00e-42	163.00
IUUC-Apl-003390	Anas platyrhynchos	44.40	2.00e-56	211.00
IUUC-Aca-004975	Anolis carolinensis	44.44	1.00e-59	221.00
IUUC-Aly-006355	Arabidopsis lyrata	29.79	3.00e-39	154.00
IUUC-Ath-007423	Arabidopsis thaliana	31.34	4.00e-39	153.00
IUUC-Ago-007948	Ashbya gossypii	41.27	7.00e-69	253.00
IUUC-Acl-008148	Aspergillus clavatus	89.15	0.00e+00	717.00
IUUC-Afl-008562	Aspergillus flavus	84.09	0.00e+00	654.00
IUUC-Ani-009254	Aspergillus nidulans	85.32	0.00e+00	710.00
IUUC-Ang-009798	Aspergillus niger	85.78	0.00e+00	662.00
IUUC-Aor-010066	Aspergillus oryzae	84.09	0.00e+00	654.00
IUUC-Ate-010266	Aspergillus terreus	87.89	0.00e+00	691.00
IUUC-Ame-010727	Astyanax mexicanus	43.96	9.00e-60	222.00
IUUC-Bta-012655	Bos taurus	44.61	1.00e-59	222.00
IUUC-Bci-013627	Botrytis cinerea	62.30	5.00e-134	469.00
IUUC-Bdi-014739	Brachypodium distachyon	30.18	4.00e-46	176.00
IUUC-Bol-015492	Brassica oleracea	29.12	2.00e-43	167.00
IUUC-Bra-017319	Brassica rapa	33.33	2.00e-34	138.00
IUUC-Cel-018503	Caenorhabditis elegans	30.07	6.00e-47	179.00
IUUC-Cja-018829	Callithrix jacchus	41.28	3.00e-54	203.00
IUUC-Cfa-020858	Canis familiaris	41.11	3.00e-56	210.00
IUUC-Cpo-022235	Cavia porcellus	44.19	2.00e-58	218.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	33.57	8.00e-39	152.00
IUUC-Csa-023963	Chlorocebus sabaeus	41.05	5.00e-55	206.00
IUUC-Cho-024328	Choloepus hoffmanni	46.02	1.00e-54	205.00
IUUC-Cin-025343	Ciona intestinalis	41.88	2.00e-51	194.00
IUUC-Csv-025920	Ciona savignyi	35.20	1.00e-63	234.00
IUUC-Cgl-026425	Colletotrichum gloeosporioides	69.93	5.00e-55	206.00
IUUC-Cne-026947	Cryptococcus neoformans	50.47	8.00e-101	358.00
IUUC-Dre-027490	Danio rerio	43.96	8.00e-60	222.00
IUUC-Dno-030057	Dasypus novemcinctus	44.40	3.00e-56	210.00
IUUC-Dor-030472	Dipodomys ordii	43.70	5.00e-54	203.00
IUUC-Dse-031215	Dothistroma septosporum	49.89	4.00e-117	412.00
IUUC-Dme-031881	Drosophila melanogaster	34.53	1.00e-29	122.00
IUUC-Ete-032362	Echinops telfairi	46.08	5.00e-49	186.00
IUUC-Eca-034362	Equus caballus	44.40	3.00e-56	210.00
IUUC-Eeu-034479	Erinaceus europaeus	34.91	8.00e-23	98.60
IUUC-Fca-036230	Felis catus	44.57	5.00e-56	209.00
IUUC-Fal-036782	Ficedula albicollis	44.23	5.00e-56	210.00
IUUC-Fox-037797	Fusarium oxysporum	69.55	8.00e-97	345.00
IUUC-Fso-038174	Fusarium solani	68.80	2.00e-95	341.00
IUUC-Gmo-039706	Gadus morhua	33.02	1.00e-54	205.00
IUUC-Ggr-040113	Gaeumannomyces graminis	69.66	7.00e-103	365.00
IUUC-Gga-040690	Gallus gallus	44.61	1.00e-59	222.00
IUUC-Gac-041360	Gasterosteus aculeatus	43.59	2.00e-59	221.00
IUUC-Gma-043876	Glycine max	43.75	1.00e-55	208.00
IUUC-Ggo-045610	Gorilla gorilla	28.38	6.00e-31	126.00
IUUC-Hsa-046782	Homo sapiens	43.97	3.00e-55	207.00
IUUC-Hvu-047851	Hordeum vulgare	30.88	2.00e-46	177.00
IUUC-Itr-048693	Ictidomys tridecemlineatus	43.97	2.00e-55	208.00
IUUC-Kpa-049378	Komagataella pastoris	47.57	2.00e-73	268.00
IUUC-Lch-050413	Latimeria chalumnae	45.37	5.00e-54	203.00
IUUC-Lpe-051205	Leersia perrieri	31.15	2.00e-46	177.00
IUUC-Loc-052379	Lepisosteus oculatus	34.54	2.00e-37	147.00
IUUC-Lma-052948	Leptosphaeria maculans	61.95	2.00e-150	523.00
IUUC-Laf-054007	Loxodonta africana	44.24	2.00e-59	221.00
IUUC-Mcc-055304	Macaca mulatta	34.14	1.00e-36	145.00
IUUC-Meu-056020	Macropus eugenii	30.04	4.00e-29	119.00
IUUC-Mor-057125	Magnaporthe oryzae	55.72	2.00e-134	470.00
IUUC-Mpo-057416	Magnaporthe poae	28.83	5.00e-28	117.00
IUUC-Mtr-058536	Medicago truncatula	30.91	3.00e-45	174.00
IUUC-Mla-058885	Melampsora laricipopulina	35.80	1.00e-12	64.70
IUUC-Mga-059795	Meleagris gallopavo	44.40	3.00e-56	210.00
IUUC-Mvi-060219	Microbotryum violaceum	48.61	2.00e-100	357.00
IUUC-Mmr-061096	Microcebus murinus	42.16	6.00e-57	213.00
IUUC-Mdo-062881	Monodelphis domestica	44.24	5.00e-59	219.00
IUUC-Mmu-063787	Mus musculus	44.24	2.00e-59	221.00
IUUC-Mac-064838	Musa acuminata	30.72	1.00e-46	178.00
IUUC-Mpu-066019	Mustela putorius furo	43.21	2.00e-57	214.00
IUUC-Mlu-068016	Myotis lucifugus	44.61	1.00e-59	221.00
IUUC-Nfi-068424	Neosartorya fischeri	97.25	0.00e+00	783.00
IUUC-Ncr-068833	Neurospora crassa	56.38	1.00e-130	458.00
IUUC-Nle-069047	Nomascus leucogenys	33.33	3.00e-39	153.00
IUUC-Opr-070933	Ochotona princeps	47.06	3.00e-39	154.00
IUUC-Ont-072495	Oreochromis niloticus	44.32	9.00e-60	222.00
IUUC-Oan-073084	Ornithorhynchus anatinus	45.58	3.00e-54	204.00
IUUC-Ocu-074689	Oryctolagus cuniculus	44.57	4.00e-59	220.00
IUUC-Oba-075601	Oryza barthii	39.19	3.00e-38	150.00
IUUC-Obr-076476	Oryza brachyantha	30.68	7.00e-46	176.00
IUUC-Ogl-077630	Oryza glaberrima	31.15	2.00e-46	177.00
IUUC-Ogu-078089	Oryza glumaepatula	39.19	2.00e-38	150.00
IUUC-Oin-079071	Oryza indica	39.34	2.00e-38	150.00
IUUC-Olo-080657	Oryza longistaminata	31.15	9.00e-45	174.00
IUUC-Ome-081702	Oryza meridionalis	30.68	4.00e-43	167.00
IUUC-Oni-083063	Oryza nivara	39.19	2.00e-38	150.00
IUUC-Opu-083460	Oryza punctata	31.15	8.00e-45	174.00
IUUC-Oru-084845	Oryza rufipogon	39.19	3.00e-38	150.00
IUUC-Osa-086113	Oryza sativa	39.19	2.00e-38	150.00
IUUC-Ola-086628	Oryzias latipes	34.43	2.00e-40	157.00
IUUC-Olu-087808	Ostreococcus lucimarinus	30.88	1.00e-40	158.00
IUUC-Oga-088894	Otolemur garnettii	41.49	1.00e-55	208.00
IUUC-Oar-089850	Ovis aries	44.02	3.00e-56	210.00
IUUC-Ptr-090456	Pan troglodytes	43.97	2.00e-55	207.00
IUUC-Pan-092111	Papio anubis	44.19	1.00e-58	218.00
IUUC-Psi-094095	Pelodiscus sinensis	44.23	2.00e-56	211.00
IUUC-Pma-094403	Petromyzon marinus	29.77	2.00e-29	121.00
IUUC-Pno-095015	Phaeosphaeria nodorum	61.50	4.00e-140	489.00
IUUC-Ppa-095480	Physcomitrella patens	30.94	6.00e-42	163.00
IUUC-Pfo-096987	Poecilia formosa	44.12	1.00e-59	221.00
IUUC-Pab-097754	Pongo abelii	43.97	4.00e-55	207.00
IUUC-Pop-099157	Populus trichocarpa	33.33	3.00e-38	150.00
IUUC-Pca-100176	Procavia capensis	26.02	2.00e-23	101.00
IUUC-Ppe-101799	Prunus persica	31.58	3.00e-40	157.00
IUUC-Pva-103047	Pteropus vampyrus	41.81	3.00e-56	210.00
IUUC-Pgr-103258	Puccinia graminis	21.86	3.00e-10	58.20
IUUC-Ptt-103915	Puccinia triticina	23.19	7.00e-16	77.00
IUUC-Pte-104139	Pyrenophora teres	61.02	1.00e-139	488.00
IUUC-Pyt-104488	Pyrenophora triticirepentis	60.00	7.00e-140	488.00
IUUC-Rno-105990	Rattus norvegicus	44.61	1.00e-59	222.00
IUUC-Sce-106327	Saccharomyces cerevisiae	35.95	2.00e-78	284.00
IUUC-Sha-106581	Sarcophilus harrisii	43.63	2.00e-55	207.00
IUUC-Sja-107913	Schizosaccharomyces japonicus	38.06	8.00e-75	272.00
IUUC-Spo-108068	Schizosaccharomyces pombe	52.02	1.00e-67	248.00
IUUC-Ssl-108418	Sclerotinia sclerotiorum	61.56	3.00e-142	496.00
IUUC-Smo-109446	Selaginella moellendorffii	32.48	6.00e-49	186.00
IUUC-Sit-110095	Setaria italica	31.15	8.00e-44	169.00
IUUC-Sly-111030	Solanum lycopersicum	29.80	1.00e-44	172.00
IUUC-Stu-111954	Solanum tuberosum	28.47	2.00e-33	134.00
IUUC-Sar-113276	Sorex araneus	35.50	2.00e-23	100.00
IUUC-Sbi-114020	Sorghum bicolor	29.72	6.00e-44	169.00
IUUC-Sre-115219	Sporisorium reilianum	49.56	7.00e-103	365.00
IUUC-Ssc-116360	Sus scrofa	45.35	5.00e-60	223.00
IUUC-Tgu-116951	Taeniopygia guttata	44.40	2.00e-56	211.00
IUUC-Tru-117889	Takifugu rubripes	41.46	2.00e-56	211.00
IUUC-Tsy-119533	Tarsius syrichta	32.50	8.00e-18	81.60
IUUC-Tni-119729	Tetraodon nigroviridis	33.33	2.00e-33	134.00
IUUC-Tca-121732	Theobroma cacao	31.02	3.00e-36	144.00
IUUC-Tre-121895	Trichoderma reesei	57.21	3.00e-135	473.00
IUUC-Tvi-122311	Trichoderma virens	56.19	3.00e-136	476.00
IUUC-Tae-124901	Triticum aestivum	30.88	2.00e-46	177.00
IUUC-Tur-126757	Triticum urartu	30.41	5.00e-45	173.00
IUUC-Ttr-128940	Tursiops truncatus	34.35	9.00e-33	132.00
IUUC-Uma-129438	Ustilago maydis	48.87	2.00e-93	334.00
IUUC-Vda-129782	Verticillium dahliae	53.93	4.00e-92	329.00
IUUC-Vvi-131674	Vitis vinifera	30.54	3.00e-46	177.00
IUUC-Xtr-131806	Xenopus tropicalis	33.70	2.00e-39	154.00
IUUC-Xma-133370	Xiphophorus maculatus	44.12	1.00e-59	221.00
IUUC-Yli-134337	Yarrowia lipolytica	48.64	4.00e-97	346.00
IUUC-Zma-135902	Zea mays	29.48	3.00e-35	141.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence