iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007941

Ensembl Protein ID

AAS52370

UniProt Accession

Q758R7; MDV1_ASHGO

Genbank Protein ID

AAS52370.1

Protein Name

Mitochondrial division protein 1

Genbank Nucleotide ID

AE016818

Gene Name

MDV1; AEL314W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AEL314W	AAS52370	AAS52370

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-43	141.8	605	639
UBD/Beta-Prp	1.00e-62	209.9	404	714

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH+d vt+l+f d   lv+Gs D++i++WDlrtg+l
   Q: 605  GHSDAVTSLQF-DsLNLVTGSLDNSIRIWDLRTGTL 639
           8**********.33559****************987 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls..........tgkcvhtlkg 92
            ++ ++h++ +tc++f  p+++l+ +g  d tikvw++++ k ++s+ gh a+v+++++++   +l+tg++D+++k wd++          +  c++t+  
   Q: 404  LSFDSAHEDNVTCLDFnLPFGTLCSAGKLDPTIKVWNLSKNKHVASITGHLATVSCMQMDQYN-TLITGGRDALLKMWDIQkaidndsipsDEVCIYTFDS 503
           678899*******************************************************96.************************************* PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqclee...................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           h d++++lsf +  + lvsGs+drtir wdl++g+c+++                   +l+ +++   + ++++ +  l++G++D++vrlWdl++g+++rt
   Q: 504  HIDEITALSFEA--NNLVSGSQDRTIRQWDLNNGKCVQTldinfatggnlsrsmigsgFLNTNNDHPIIGAIQCYDAALATGTKDGIVRLWDLRSGRVVRT 602
           ************..9*******************************************999999999999999999************************* PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsf 275
           l+g h d+v+sl+fds    lv+gsld+++++wdl+tg+  +t+  ++ +v++++f+   + +v+++++g++++++ + ++ + +    ++s  +v ++++
   Q: 603  LEG-HSDAVTSLQFDS--LNLVTGSLDNSIRIWDLRTGTLADTF-SYEHPVTCLQFD--LNKIVVANQEGTVKVYNRQEKKHWFCGGD-EHSENAVEYVRY 696
           **9.************..78******************966666.6899********..99***************777777766665.5599999999** PP
   S: 276  gdnvlvlgsedskvniwk 293
           +d +lv+g++++++n w+
   Q: 697  KDGYLVEGRANGDINAWA 714
           *****************7 PP

Organism

Ashbya gossypii

Functional Description
(View)

Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity).

Protein Sequence
(Fasta)

MSSGTSGDQI SHFGKTLTTT ASLVFGSQSM EDTILSYSSP YKKILHDTIT SSGGTSSLMK 60
VERSGRMFTP FRTRNSAFQD IFHASSGRGY FKNGFSDTRT SFQVLSYLSD AMLADIPSSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTAGTG GTACATCTGG CGACCAGATT TCGCATTTTG GGAAGACGCT GACGACCACT 60
GCGTCGTTAG TGTTCGGCTC GCAGTCCATG GAGGATACTA TCCTATCGTA CAGCAGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0496--Mitochondrion
KW-1000--Mitochondrion outer membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005741--C:mitochondrial outer membrane
GO:0000266--P:mitochondrial fission
GO:0000002--P:mitochondrial genome maintenance
GO:0016559--P:peroxisome fission
GO:0090141--P:positive regulation of mitochondrial fission

KEGG

ago:AGOS_AEL314W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008165	Aspergillus clavatus	43.96	3.00e-84	303.00
IUUC-Afl-008726	Aspergillus flavus	42.58	2.00e-79	286.00
IUUC-Afu-009086	Aspergillus fumigatus	44.08	5.00e-82	296.00
IUUC-Ani-009192	Aspergillus nidulans	38.10	8.00e-91	325.00
IUUC-Ang-009540	Aspergillus niger	36.21	2.00e-88	317.00
IUUC-Aor-010128	Aspergillus oryzae	42.58	2.00e-80	291.00
IUUC-Ate-010579	Aspergillus terreus	34.03	7.00e-93	332.00
IUUC-Bgr-012212	Blumeria graminis	30.77	2.00e-92	330.00
IUUC-Bci-013867	Botrytis cinerea	35.51	6.00e-93	332.00
IUUC-Cgl-026600	Colletotrichum gloeosporioides	33.29	7.00e-97	345.00
IUUC-Cne-027030	Cryptococcus neoformans	31.39	2.00e-53	201.00
IUUC-Cme-027168	Cyanidioschyzon merolae	26.47	5.00e-24	104.00
IUUC-Dse-031481	Dothistroma septosporum	39.65	1.00e-80	291.00
IUUC-Fox-037725	Fusarium oxysporum	32.43	9.00e-98	348.00
IUUC-Fso-038270	Fusarium solani	31.76	1.00e-92	332.00
IUUC-Ggr-039837	Gaeumannomyces graminis	31.36	2.00e-92	330.00
IUUC-Kpa-049115	Komagataella pastoris	36.57	6.00e-115	405.00
IUUC-Lma-053086	Leptosphaeria maculans	34.60	4.00e-88	317.00
IUUC-Meu-056080	Macropus eugenii	25.93	3.00e-20	92.80
IUUC-Mor-056934	Magnaporthe oryzae	35.04	2.00e-93	334.00
IUUC-Mpo-057367	Magnaporthe poae	31.04	1.00e-93	334.00
IUUC-Mla-058916	Melampsora laricipopulina	35.44	1.00e-56	211.00
IUUC-Mvi-060499	Microbotryum violaceum	30.27	2.00e-53	201.00
IUUC-Nfi-068414	Neosartorya fischeri	37.88	8.00e-88	315.00
IUUC-Ncr-068861	Neurospora crassa	33.54	1.00e-99	355.00
IUUC-Pno-095117	Phaeosphaeria nodorum	31.97	1.00e-90	325.00
IUUC-Pgr-103442	Puccinia graminis	31.49	1.00e-51	196.00
IUUC-Ptt-103881	Puccinia triticina	29.15	6.00e-62	229.00
IUUC-Pte-104262	Pyrenophora teres	27.87	7.00e-62	229.00
IUUC-Pyt-104679	Pyrenophora triticirepentis	41.76	6.00e-82	295.00
IUUC-Sce-106213	Saccharomyces cerevisiae	41.19	6.00e-151	525.00
IUUC-Sja-107810	Schizosaccharomyces japonicus	27.97	3.00e-58	217.00
IUUC-Spo-108016	Schizosaccharomyces pombe	31.39	6.00e-64	236.00
IUUC-Ssl-108498	Sclerotinia sclerotiorum	31.04	3.00e-87	313.00
IUUC-Sre-115117	Sporisorium reilianum	37.31	3.00e-48	184.00
IUUC-Tre-122068	Trichoderma reesei	33.02	3.00e-89	321.00
IUUC-Tvi-122485	Trichoderma virens	32.93	2.00e-93	335.00
IUUC-Tme-127188	Tuber melanosporum	32.78	9.00e-104	368.00
IUUC-Uma-129325	Ustilago maydis	33.00	7.00e-60	223.00
IUUC-Vda-130011	Verticillium dahliae	31.66	8.00e-97	345.00
IUUC-Yli-134598	Yarrowia lipolytica	41.51	3.00e-99	353.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence