iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oru-084789

Ensembl Protein ID

ORUFI02G39240.1

UniProt Accession

A0A0E0NN02; A0A0E0NN02_ORYRU

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ORUFI02G39240	ORUFI02G39240.1	ORUFI02G39240.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.40e-75	255.9	2	318

Active Site

Position(s)	Description	Evidence
82	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
157	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCa 100
           +w+++esdPg+ft+l+++  vk++ qveelysLd ++++ + +pv+gl++lFk+   ++ +r +           +d   ++ffa qvi+N+Ca
   Q: 2    SWCTIESDPGVFTELIQEMQVKGV-QVEELYSLDVDSISEL-RPVYGLIFLFKWMAGEKDERPV----------VKDPNPNLFFASQVIPNACA 83
           7***********************.****************.**************99999933..........357779************** PP
   S: 101  tyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeld 194
           t+A+ls l n  +   d+G++ls+lke+t a+ p++k+la++n++ ++ +hns+ar+e++ ++e++++ +   ++e++hf+sy + +g lyeld
   Q: 84   TQAILSILMNRPEI--DIGPELSNLKEFTGAFAPDMKGLAINNSDSIRTAHNSFARPEPFVSDEQRAAGK---DDEVYHFISYLPFEGVLYELD 172
           **********9998..***********************************************9997775...9******************** PP
   S: 195  glkpfPldlgkk...keteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid..............keLlkLlkdies 271
           glk+ P+ lg++    ++ ++   ++ v+   +ri+ +++ eirfnl+ai ++r+ ++t+ l+ l+                + L + l ++ s
   Q: 173  GLKEGPISLGQCsggPDDLDWLRMVQPVI--QKRIERYSQSEIRFNLMAIIKNRKDVYTAELKELEKRrdqllqemnessaaESLNSELAEVTS 264
           ************43335556666666666..*****************************9987766688***********98899999***** PP
   S: 272  eeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveet 325
            +e  ++++  e+ek kk+  ++irR++ny  f++ f+k+la++++l+ lve+ 
   Q: 265  AIETVSEKIIMEEEKFKKWRTENIRRKHNYIPFLFNFLKMLAEKKQLKPLVEKA 318
           ***************************************************983 PP

Organism

Oryza rufipogon

Protein Sequence
(Fasta)

MSWCTIESDP GVFTELIQEM QVKGVQVEEL YSLDVDSISE LRPVYGLIFL FKWMAGEKDE 60
RPVVKDPNPN LFFASQVIPN ACATQAILSI LMNRPEIDIG PELSNLKEFT GAFAPDMKGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAAAATCAT TGCGCCTCGA CTCGAGTATC TCTCCCCCGC CGCCTTCCGC TCGTCGCGCA 60
TCTGGCGAGC AGAGCAGGGG AGGGGGCGCC GCCGCCGCCG CCGCCGCCGT CCTTGTGCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	84.73	1.00e-163	568.00
IUUC-Aml-001866	Ailuropoda melanoleuca	50.00	7.00e-85	306.00
IUUC-Atr-002966	Amborella trichopoda	71.86	7.00e-137	479.00
IUUC-Apl-003306	Anas platyrhynchos	43.98	8.00e-78	283.00
IUUC-Aca-004763	Anolis carolinensis	48.43	3.00e-83	300.00
IUUC-Aly-005581	Arabidopsis lyrata	75.15	1.00e-135	474.00
IUUC-Ath-007283	Arabidopsis thaliana	76.67	1.00e-140	491.00
IUUC-Ago-007999	Ashbya gossypii	35.63	6.00e-35	140.00
IUUC-Acl-008231	Aspergillus clavatus	50.21	3.00e-61	228.00
IUUC-Afl-008557	Aspergillus flavus	47.13	5.00e-60	223.00
IUUC-Afu-008988	Aspergillus fumigatus	50.83	2.00e-61	228.00
IUUC-Ani-009420	Aspergillus nidulans	42.60	1.00e-62	232.00
IUUC-Ang-009859	Aspergillus niger	48.77	4.00e-57	214.00
IUUC-Aor-010145	Aspergillus oryzae	47.13	5.00e-60	223.00
IUUC-Ate-010347	Aspergillus terreus	46.90	1.00e-59	223.00
IUUC-Ame-010791	Astyanax mexicanus	47.89	7.00e-86	309.00
IUUC-Bgr-012298	Blumeria graminis	41.18	5.00e-58	217.00
IUUC-Bta-013251	Bos taurus	49.69	6.00e-85	306.00
IUUC-Bci-013786	Botrytis cinerea	40.95	8.00e-61	226.00
IUUC-Bdi-014132	Brachypodium distachyon	89.67	1.00e-168	585.00
IUUC-Bol-015611	Brassica oleracea	73.86	2.00e-141	494.00
IUUC-Bra-017769	Brassica rapa	73.86	7.00e-141	492.00
IUUC-Cel-018604	Caenorhabditis elegans	43.61	9.00e-70	256.00
IUUC-Cja-019768	Callithrix jacchus	45.95	1.00e-79	289.00
IUUC-Cfa-020207	Canis familiaris	50.00	7.00e-85	306.00
IUUC-Cpo-021925	Cavia porcellus	47.80	2.00e-78	285.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	51.85	8.00e-86	309.00
IUUC-Csa-023958	Chlorocebus sabaeus	50.00	6.00e-85	306.00
IUUC-Cho-024928	Choloepus hoffmanni	52.70	5.00e-16	77.80
IUUC-Cin-025771	Ciona intestinalis	41.93	6.00e-70	256.00
IUUC-Csv-026149	Ciona savignyi	44.58	8.00e-74	270.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	34.29	2.00e-46	179.00
IUUC-Cne-026955	Cryptococcus neoformans	34.63	5.00e-48	184.00
IUUC-Cme-027104	Cyanidioschyzon merolae	30.56	7.00e-45	173.00
IUUC-Dre-027409	Danio rerio	47.89	5.00e-86	310.00
IUUC-Dno-028921	Dasypus novemcinctus	50.00	1.00e-84	305.00
IUUC-Dor-030891	Dipodomys ordii	41.90	1.00e-34	140.00
IUUC-Dse-031170	Dothistroma septosporum	41.18	3.00e-61	228.00
IUUC-Dme-031677	Drosophila melanogaster	48.45	7.00e-83	300.00
IUUC-Ete-032646	Echinops telfairi	41.26	2.00e-42	166.00
IUUC-Eca-033776	Equus caballus	48.83	3.00e-76	277.00
IUUC-Eeu-035305	Erinaceus europaeus	43.41	3.00e-36	144.00
IUUC-Fca-035846	Felis catus	46.09	3.00e-80	291.00
IUUC-Fal-037597	Ficedula albicollis	47.83	5.00e-73	266.00
IUUC-Fox-037670	Fusarium oxysporum	45.30	5.00e-51	194.00
IUUC-Fso-038243	Fusarium solani	46.09	1.00e-50	192.00
IUUC-Gmo-038499	Gadus morhua	45.91	3.00e-76	277.00
IUUC-Ggr-039975	Gaeumannomyces graminis	43.55	3.00e-53	201.00
IUUC-Gga-040904	Gallus gallus	48.20	3.00e-87	314.00
IUUC-Gac-042058	Gasterosteus aculeatus	48.74	7.00e-84	303.00
IUUC-Gma-043030	Glycine max	77.71	8.00e-151	525.00
IUUC-Ggo-044699	Gorilla gorilla	46.45	5.00e-73	267.00
IUUC-Hsa-046227	Homo sapiens	50.31	2.00e-85	308.00
IUUC-Hvu-047359	Hordeum vulgare	86.50	7.00e-163	565.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	44.99	2.00e-79	288.00
IUUC-Lch-049829	Latimeria chalumnae	49.37	9.00e-85	306.00
IUUC-Lpe-050899	Leersia perrieri	98.10	4.00e-168	583.00
IUUC-Loc-052264	Lepisosteus oculatus	47.96	5.00e-82	296.00
IUUC-Lma-053110	Leptosphaeria maculans	50.88	1.00e-54	206.00
IUUC-Laf-053639	Loxodonta africana	50.00	7.00e-85	306.00
IUUC-Mcc-055506	Macaca mulatta	50.00	5.00e-85	307.00
IUUC-Meu-056267	Macropus eugenii	40.53	4.00e-49	189.00
IUUC-Mor-057001	Magnaporthe oryzae	46.31	1.00e-56	213.00
IUUC-Mpo-057608	Magnaporthe poae	44.39	6.00e-37	146.00
IUUC-Mtr-057731	Medicago truncatula	76.28	1.00e-145	508.00
IUUC-Mla-059016	Melampsora laricipopulina	46.50	2.00e-45	174.00
IUUC-Mga-060178	Meleagris gallopavo	46.67	3.00e-78	284.00
IUUC-Mvi-060353	Microbotryum violaceum	38.58	3.00e-55	207.00
IUUC-Mmr-060738	Microcebus murinus	50.63	1.00e-85	309.00
IUUC-Mdo-062266	Monodelphis domestica	51.92	4.00e-59	220.00
IUUC-Mmu-063619	Mus musculus	50.00	2.00e-84	305.00
IUUC-Mac-065301	Musa acuminata	80.06	5.00e-154	536.00
IUUC-Mpu-066058	Mustela putorius furo	49.06	3.00e-84	304.00
IUUC-Mlu-067292	Myotis lucifugus	49.69	9.00e-85	306.00
IUUC-Nfi-068275	Neosartorya fischeri	40.87	3.00e-63	234.00
IUUC-Ncr-068713	Neurospora crassa	39.14	8.00e-59	219.00
IUUC-Nle-069013	Nomascus leucogenys	50.31	7.00e-86	310.00
IUUC-Opr-070628	Ochotona princeps	43.31	2.00e-73	268.00
IUUC-Ont-072688	Oreochromis niloticus	48.12	1.00e-82	299.00
IUUC-Oan-073004	Ornithorhynchus anatinus	48.18	8.00e-62	229.00
IUUC-Ocu-074303	Oryctolagus cuniculus	49.38	4.00e-84	305.00
IUUC-Oba-075002	Oryza barthii	99.70	2.00e-179	620.00
IUUC-Obr-076392	Oryza brachyantha	97.15	5.00e-166	576.00
IUUC-Ogl-077271	Oryza glaberrima	99.70	2.00e-179	620.00
IUUC-Ogu-078493	Oryza glumaepatula	100.00	3.00e-180	623.00
IUUC-Oin-080084	Oryza indica	100.00	3.00e-180	623.00
IUUC-Olo-080803	Oryza longistaminata	99.70	9.00e-180	621.00
IUUC-Ome-081146	Oryza meridionalis	99.09	1.00e-178	618.00
IUUC-Oni-082146	Oryza nivara	100.00	3.00e-180	623.00
IUUC-Opu-083633	Oryza punctata	99.37	9.00e-169	585.00
IUUC-Osa-086196	Oryza sativa	100.00	3.00e-180	623.00
IUUC-Ola-087126	Oryzias latipes	48.11	2.00e-82	298.00
IUUC-Olu-087665	Ostreococcus lucimarinus	46.49	2.00e-72	265.00
IUUC-Oga-089140	Otolemur garnettii	46.67	8.00e-81	293.00
IUUC-Oar-090296	Ovis aries	49.21	2.00e-83	301.00
IUUC-Ptr-090566	Pan troglodytes	50.31	2.00e-85	308.00
IUUC-Pan-092052	Papio anubis	50.00	6.00e-85	306.00
IUUC-Psi-093723	Pelodiscus sinensis	47.49	1.00e-75	275.00
IUUC-Pma-094568	Petromyzon marinus	44.44	7.00e-68	249.00
IUUC-Pno-095120	Phaeosphaeria nodorum	49.56	2.00e-55	208.00
IUUC-Ppa-095761	Physcomitrella patens	71.55	1.00e-138	485.00
IUUC-Pfo-096210	Poecilia formosa	49.68	3.00e-84	304.00
IUUC-Pab-098463	Pongo abelii	50.31	2.00e-85	308.00
IUUC-Pop-099109	Populus trichocarpa	74.77	2.00e-146	511.00
IUUC-Pca-100108	Procavia capensis	51.45	9.00e-68	249.00
IUUC-Ppe-101176	Prunus persica	75.90	8.00e-146	508.00
IUUC-Pva-102629	Pteropus vampyrus	52.72	9.00e-70	256.00
IUUC-Pgr-103419	Puccinia graminis	39.52	6.00e-57	213.00
IUUC-Pte-104207	Pyrenophora teres	52.41	2.00e-39	154.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	41.59	5.00e-59	220.00
IUUC-Rno-105579	Rattus norvegicus	43.75	1.00e-72	266.00
IUUC-Sha-106894	Sarcophilus harrisii	48.58	1.00e-71	262.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	40.72	4.00e-63	234.00
IUUC-Spo-108371	Schizosaccharomyces pombe	43.33	8.00e-69	253.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	38.62	5.00e-48	183.00
IUUC-Smo-109396	Selaginella moellendorffii	72.84	1.00e-133	468.00
IUUC-Sit-110630	Setaria italica	87.50	1.00e-164	571.00
IUUC-Sly-110972	Solanum lycopersicum	76.77	2.00e-143	501.00
IUUC-Stu-112185	Solanum tuberosum	77.41	6.00e-156	542.00
IUUC-Sar-113294	Sorex araneus	43.60	6.00e-72	263.00
IUUC-Sbi-113951	Sorghum bicolor	86.59	6.00e-162	562.00
IUUC-Ssc-115501	Sus scrofa	47.57	2.00e-77	281.00
IUUC-Tgu-117152	Taeniopygia guttata	48.16	5.00e-73	266.00
IUUC-Tru-118388	Takifugu rubripes	48.11	6.00e-84	303.00
IUUC-Tsy-119109	Tarsius syrichta	50.31	2.00e-85	308.00
IUUC-Tni-120048	Tetraodon nigroviridis	48.11	5.00e-84	303.00
IUUC-Tca-121750	Theobroma cacao	76.95	4.00e-155	540.00
IUUC-Tre-122130	Trichoderma reesei	38.24	4.00e-55	207.00
IUUC-Tvi-122284	Trichoderma virens	39.34	2.00e-53	202.00
IUUC-Tae-124082	Triticum aestivum	86.50	4.00e-163	566.00
IUUC-Tme-127187	Tuber melanosporum	40.60	7.00e-67	246.00
IUUC-Tbe-127619	Tupaia belangeri	43.48	2.00e-57	214.00
IUUC-Ttr-128867	Tursiops truncatus	45.34	8.00e-57	213.00
IUUC-Vda-129912	Verticillium dahliae	38.33	2.00e-55	208.00
IUUC-Vpa-130552	Vicugna pacos	52.66	3.00e-59	221.00
IUUC-Vvi-130881	Vitis vinifera	78.08	3.00e-150	523.00
IUUC-Xtr-131934	Xenopus tropicalis	47.60	1.00e-86	312.00
IUUC-Xma-133312	Xiphophorus maculatus	49.68	2.00e-84	305.00
IUUC-Yli-134487	Yarrowia lipolytica	34.91	2.00e-52	198.00
IUUC-Zma-135639	Zea mays	75.41	6.00e-148	516.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence