iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-33	113.6	262	299
UBD/Beta-Prp	1.60e-53	182.7	211	510

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H d+v c++f  d  +l+sGs Dg+ik+W++rtgv+++
   Q: 262  HDDPVLCIDFsRDsEMLASGSQDGKIKIWRIRTGVCIR 299
           99*********777**********************86 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl........lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
            +ks   c  fspd+++la++s dg i+vwd+ +gkl         +s+  h+++v +++fs+d+++l++gs+D+ ik+w ++tg c++ + +h++ v
   Q: 211  GKKSHAECARFSPDGQFLASSSVDGFIEVWDYISGKLkkdlqyqaDESFMMHDDPVLCIDFSRDSEMLASGSQDGKIKIWRIRTGVCIRRFDAHSQGV 308
           5678899******************************888888877888889999******************************************* PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl......tgghtdsvysls.f 188
           +slsfs++g+ l+s+s d+t+r+  l++g+ l+  ++gh++ vn++ + +dg+ ++++s D tv++Wd+kt ++l+t+      +g  + sv+s+  f
   Q: 309  TSLSFSRDGSQLLSTSFDQTARIHGLKSGKLLK-EFRGHTSYVNHAIFTSDGSRIITASSDCTVKVWDSKTTDCLQTFkpppplRG-TDASVNSIHlF 404
           *********************************.*************************************************777.*********99 PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlng.htdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlg 283
            +n +++v + + +++ +  lq g++v+++    ++    v+++   +++++++ ++D+ +++++++sg l + +  h++ vi +++ ++ +n l++ 
   Q: 405  PKNTEHIVVCNKTSSIYIMTLQ-GQVVKSFSSgNREGGDFVAACvsTKGDWIYCIGEDKKLYCFNYQSGGLEHFMMVHEKDVIGITH-HPHRNLLATY 500
           99*******************6.6677777651555555555545578***************************************.********** PP
   S: 284  sedskvniwk 293
           sed++ ++wk
   Q: 501  SEDCTMKLWK 510
           *********8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Auxiliary spliceosomal protein involved in splicing of specific pre-mRNAs that affect multiple aspects of development. Required for proper accumulation of SMU2.

Protein Sequence
(Fasta)

MALEIEARDV IKIMLQFCKE NSLNQTFQTL QSECQVSLNT VDSVETFISD INSGRWDSVL 60
PQVSQLKLPR NKLEDLYEQI VLEMIELREL DTARAILRQT QVMGVMKQEQ AERYLRMEHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCGCGTGT GTTTTCTGCT GCATTTTTAC CTCTTAGCGT CTCCGGCGAA AACCCACTAC 60
GACTGAGTAT GGCGCTCGAA ATCGAAGCTC GAGAGTAAGA TTTCGCTTTC TCTTACAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR006595--CTLH_C
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0008380--P:RNA splicing

KEGG

ath:AT1G73720

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000857	Aegilops tauschii	86.11	6.00e-73	265.00
IUUC-Aml-001330	Ailuropoda melanoleuca	64.72	0.00e+00	715.00
IUUC-Atr-002570	Amborella trichopoda	85.13	0.00e+00	930.00
IUUC-Apl-003826	Anas platyrhynchos	65.18	0.00e+00	686.00
IUUC-Aca-005183	Anolis carolinensis	64.47	0.00e+00	709.00
IUUC-Aly-005632	Arabidopsis lyrata	97.85	0.00e+00	1049.00
IUUC-Ame-011374	Astyanax mexicanus	63.94	0.00e+00	709.00
IUUC-Bta-012890	Bos taurus	64.72	0.00e+00	715.00
IUUC-Bdi-014061	Brachypodium distachyon	82.39	0.00e+00	917.00
IUUC-Bol-016332	Brassica oleracea	91.98	0.00e+00	1003.00
IUUC-Bra-017612	Brassica rapa	91.80	0.00e+00	1004.00
IUUC-Cel-018238	Caenorhabditis elegans	50.59	4.00e-161	560.00
IUUC-Cja-019336	Callithrix jacchus	64.72	0.00e+00	715.00
IUUC-Cfa-021108	Canis familiaris	64.91	0.00e+00	716.00
IUUC-Cpo-022052	Cavia porcellus	64.72	0.00e+00	715.00
IUUC-Cre-022595	Chlamydomonas reinhardtii	64.26	0.00e+00	713.00
IUUC-Csa-023488	Chlorocebus sabaeus	64.72	0.00e+00	715.00
IUUC-Cho-025010	Choloepus hoffmanni	57.12	4.00e-176	610.00
IUUC-Cin-025251	Ciona intestinalis	62.26	0.00e+00	689.00
IUUC-Csv-026092	Ciona savignyi	58.32	0.00e+00	625.00
IUUC-Dre-027382	Danio rerio	63.55	0.00e+00	704.00
IUUC-Dno-029007	Dasypus novemcinctus	64.91	0.00e+00	715.00
IUUC-Dor-030180	Dipodomys ordii	56.05	4.00e-126	443.00
IUUC-Dme-031762	Drosophila melanogaster	60.04	0.00e+00	673.00
IUUC-Ete-032933	Echinops telfairi	64.19	5.00e-170	589.00
IUUC-Eca-033864	Equus caballus	64.88	0.00e+00	703.00
IUUC-Eeu-034635	Erinaceus europaeus	59.14	5.00e-148	516.00
IUUC-Fca-036119	Felis catus	64.72	0.00e+00	715.00
IUUC-Fal-037396	Ficedula albicollis	65.33	0.00e+00	698.00
IUUC-Gmo-038962	Gadus morhua	63.35	0.00e+00	698.00
IUUC-Gga-040134	Gallus gallus	64.91	0.00e+00	715.00
IUUC-Gac-041630	Gasterosteus aculeatus	63.35	0.00e+00	704.00
IUUC-Gma-043928	Glycine max	87.25	0.00e+00	956.00
IUUC-Ggo-045061	Gorilla gorilla	64.66	0.00e+00	710.00
IUUC-Hsa-046215	Homo sapiens	64.72	0.00e+00	715.00
IUUC-Hvu-047799	Hordeum vulgare	81.94	0.00e+00	638.00
IUUC-Itr-048826	Ictidomys tridecemlineatus	64.72	0.00e+00	715.00
IUUC-Lch-050209	Latimeria chalumnae	60.31	0.00e+00	650.00
IUUC-Lpe-050740	Leersia perrieri	83.33	0.00e+00	923.00
IUUC-Loc-052739	Lepisosteus oculatus	59.92	0.00e+00	654.00
IUUC-Laf-053895	Loxodonta africana	64.59	0.00e+00	710.00
IUUC-Mcc-055183	Macaca mulatta	64.72	0.00e+00	715.00
IUUC-Mtr-057730	Medicago truncatula	84.74	0.00e+00	917.00
IUUC-Mga-059222	Meleagris gallopavo	66.03	7.00e-171	592.00
IUUC-Mmr-061749	Microcebus murinus	64.88	0.00e+00	704.00
IUUC-Mdo-062920	Monodelphis domestica	64.52	0.00e+00	713.00
IUUC-Mmu-063228	Mus musculus	64.72	0.00e+00	715.00
IUUC-Mac-065084	Musa acuminata	84.31	0.00e+00	931.00
IUUC-Mpu-066162	Mustela putorius furo	64.72	0.00e+00	715.00
IUUC-Mlu-067471	Myotis lucifugus	63.94	0.00e+00	709.00
IUUC-Nle-070129	Nomascus leucogenys	64.72	0.00e+00	715.00
IUUC-Opr-071176	Ochotona princeps	64.88	0.00e+00	703.00
IUUC-Ont-071830	Oreochromis niloticus	63.74	0.00e+00	710.00
IUUC-Oan-072778	Ornithorhynchus anatinus	64.91	0.00e+00	715.00
IUUC-Ocu-074570	Oryctolagus cuniculus	64.72	0.00e+00	715.00
IUUC-Oba-075507	Oryza barthii	82.94	0.00e+00	924.00
IUUC-Obr-076672	Oryza brachyantha	83.92	0.00e+00	933.00
IUUC-Ogl-077110	Oryza glaberrima	82.94	0.00e+00	924.00
IUUC-Ogu-077976	Oryza glumaepatula	82.94	0.00e+00	924.00
IUUC-Oin-079525	Oryza indica	82.94	0.00e+00	924.00
IUUC-Olo-080391	Oryza longistaminata	80.57	0.00e+00	913.00
IUUC-Oni-082778	Oryza nivara	82.94	0.00e+00	924.00
IUUC-Opu-083710	Oryza punctata	83.17	0.00e+00	926.00
IUUC-Oru-084250	Oryza rufipogon	82.94	0.00e+00	924.00
IUUC-Osa-085363	Oryza sativa	82.94	0.00e+00	924.00
IUUC-Ola-087092	Oryzias latipes	63.55	0.00e+00	706.00
IUUC-Olu-087753	Ostreococcus lucimarinus	52.82	1.00e-147	515.00
IUUC-Oga-088278	Otolemur garnettii	60.39	0.00e+00	638.00
IUUC-Oar-089664	Ovis aries	64.34	0.00e+00	710.00
IUUC-Ptr-090991	Pan troglodytes	64.72	0.00e+00	715.00
IUUC-Pan-092697	Papio anubis	64.72	0.00e+00	715.00
IUUC-Psi-093204	Pelodiscus sinensis	65.13	0.00e+00	697.00
IUUC-Ppa-095325	Physcomitrella patens	80.39	0.00e+00	887.00
IUUC-Pfo-096988	Poecilia formosa	63.74	0.00e+00	708.00
IUUC-Pab-098288	Pongo abelii	64.72	0.00e+00	715.00
IUUC-Pop-098787	Populus trichocarpa	85.35	0.00e+00	948.00
IUUC-Pca-100583	Procavia capensis	60.32	0.00e+00	634.00
IUUC-Ppe-101307	Prunus persica	85.69	0.00e+00	941.00
IUUC-Pva-102711	Pteropus vampyrus	64.72	0.00e+00	715.00
IUUC-Rno-105614	Rattus norvegicus	64.72	0.00e+00	715.00
IUUC-Sha-107017	Sarcophilus harrisii	64.72	0.00e+00	715.00
IUUC-Smo-108800	Selaginella moellendorffii	76.76	0.00e+00	820.00
IUUC-Sit-110278	Setaria italica	83.92	0.00e+00	906.00
IUUC-Sly-111777	Solanum lycopersicum	85.29	0.00e+00	934.00
IUUC-Stu-112293	Solanum tuberosum	85.29	0.00e+00	934.00
IUUC-Sar-112955	Sorex araneus	58.17	1.00e-178	618.00
IUUC-Sbi-114802	Sorghum bicolor	83.73	0.00e+00	902.00
IUUC-Ssc-116054	Sus scrofa	64.72	0.00e+00	715.00
IUUC-Tgu-116909	Taeniopygia guttata	64.26	0.00e+00	706.00
IUUC-Tru-118195	Takifugu rubripes	64.52	0.00e+00	716.00
IUUC-Tsy-119420	Tarsius syrichta	59.26	0.00e+00	631.00
IUUC-Tni-120416	Tetraodon nigroviridis	64.33	0.00e+00	710.00
IUUC-Tca-121653	Theobroma cacao	86.91	0.00e+00	939.00
IUUC-Tae-125609	Triticum aestivum	82.55	0.00e+00	916.00
IUUC-Tur-126197	Triticum urartu	80.87	0.00e+00	654.00
IUUC-Tbe-128009	Tupaia belangeri	65.68	3.00e-135	474.00
IUUC-Ttr-128719	Tursiops truncatus	58.09	0.00e+00	630.00
IUUC-Vpa-130579	Vicugna pacos	64.33	0.00e+00	707.00
IUUC-Vvi-131127	Vitis vinifera	86.47	0.00e+00	946.00
IUUC-Xtr-132950	Xenopus tropicalis	60.35	0.00e+00	653.00
IUUC-Xma-133537	Xiphophorus maculatus	63.74	0.00e+00	708.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence