iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dse-031268

Ensembl Protein ID

EME38244

UniProt Accession

N1PCV6; N1PCV6_DOTSN

Genbank Protein ID

EME38244.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

KB446547

Gene Name

DOTSEDRAFT_48527

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
DOTSEDRAFT_48527	EME38244	EME38244

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-30	102.3	186	218
UBD/Beta-Prp	4.00e-65	219.2	13	295

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf...sd.tllvsGsdDgtikvWDlrtg 33
           +v+ +++   sd ++l++ sdD t+k+WD++t 
   Q: 186  GVNHVDYypqSDkPYLLTTSDDRTVKIWDYTTK 218
           6899998899999****************9986 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklv 110
           +++++ ++f+p +++++t+ ++g + +w+++t++ +++++  + +v+a +f+ +++++v gs+D  ++v++++t++ + ++++h d+++++ ++p++ +++
   Q: 13   SERVKGIDFHPTEPWILTTLYSGHVYIWSYETQSIIKTFELTDVPVRAGRFIARKNWIVCGSDDFQLRVYNYNTSEKITSFEAHPDYIRAIVVHPTQPFVL 113
           678999*********************************************************************************************** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwd 208
           ++s+d ti++wd+e+g++  ++++gh++ v++++++p++ n ++s++lDrtv++W+l + +   tl+   t+ v+++++ +++  ++l++ s+d+tvk+wd
   Q: 114  TASDDMTIKLWDWEKGWKCVQVFEGHSHYVMGLAINPKDtNTFASACLDRTVKIWNLGSSTPNFTLEAHETKGVNHVDYYPQSdkPYLLTTSDDRTVKIWD 214
           ****************98888***********************************************99********9998888**************** PP
   S: 209  lqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvn 290
           + t+  + tl+ght+nv+    +p+   ++sgs+Dg+++iW   +  l ++l++  ++ ++v++ + g++ ++ g +d+ v 
   Q: 215  YTTKAQIATLEGHTSNVSFACYHPELPVIISGSEDGTVKIWHANTYRLEQSLSYGLERAWCVSY-QRGRQGIAMGFDDGAVV 295
           ***************************************************************9.65566665555555544 PP

Organism

Dothistroma septosporum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MRLDLQRQLF ARSERVKGID FHPTEPWILT TLYSGHVYIW SYETQSIIKT FELTDVPVRA 60
GRFIARKNWI VCGSDDFQLR VYNYNTSEKI TSFEAHPDYI RAIVVHPTQP FVLTASDDMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCGCTCTT GCAATTGCAA TTGTAAATTC GCTCATTCCT GTTTAGTCAC GGTCGCAGTT 60
TCCATTTATA GCGAGAGCCG CAAATTCCAC ATAAACCGAA GGAAAGAGCG ATTAGCGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	44.93	0.00e+00	753.00
IUUC-Aml-002154	Ailuropoda melanoleuca	55.03	0.00e+00	983.00
IUUC-Atr-003090	Amborella trichopoda	51.44	0.00e+00	879.00
IUUC-Apl-003976	Anas platyrhynchos	55.31	0.00e+00	977.00
IUUC-Aca-004301	Anolis carolinensis	55.68	0.00e+00	983.00
IUUC-Aly-005643	Arabidopsis lyrata	52.39	0.00e+00	877.00
IUUC-Ath-007630	Arabidopsis thaliana	52.93	0.00e+00	896.00
IUUC-Ago-007914	Ashbya gossypii	49.94	0.00e+00	849.00
IUUC-Acl-008237	Aspergillus clavatus	78.91	0.00e+00	1371.00
IUUC-Afl-008535	Aspergillus flavus	77.21	0.00e+00	1305.00
IUUC-Afu-008845	Aspergillus fumigatus	77.73	0.00e+00	1333.00
IUUC-Ani-009135	Aspergillus nidulans	78.29	0.00e+00	1323.00
IUUC-Ang-009654	Aspergillus niger	83.64	0.00e+00	1177.00
IUUC-Aor-009939	Aspergillus oryzae	78.14	0.00e+00	1382.00
IUUC-Ate-010355	Aspergillus terreus	79.47	0.00e+00	1328.00
IUUC-Ame-010922	Astyanax mexicanus	51.23	0.00e+00	851.00
IUUC-Bgr-012249	Blumeria graminis	75.82	0.00e+00	1295.00
IUUC-Bta-013579	Bos taurus	56.31	0.00e+00	890.00
IUUC-Bci-013866	Botrytis cinerea	79.44	0.00e+00	1309.00
IUUC-Bdi-015046	Brachypodium distachyon	52.32	0.00e+00	886.00
IUUC-Bol-015466	Brassica oleracea	51.95	0.00e+00	867.00
IUUC-Bra-017758	Brassica rapa	51.89	0.00e+00	893.00
IUUC-Cel-018387	Caenorhabditis elegans	50.49	0.00e+00	892.00
IUUC-Cja-019145	Callithrix jacchus	54.91	0.00e+00	980.00
IUUC-Cfa-020564	Canis familiaris	54.91	0.00e+00	980.00
IUUC-Cpo-022201	Cavia porcellus	54.96	0.00e+00	982.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	52.45	0.00e+00	837.00
IUUC-Csa-023383	Chlorocebus sabaeus	58.84	0.00e+00	761.00
IUUC-Cho-024454	Choloepus hoffmanni	51.89	0.00e+00	833.00
IUUC-Cin-025681	Ciona intestinalis	52.94	0.00e+00	899.00
IUUC-Csv-026012	Ciona savignyi	54.19	0.00e+00	901.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	71.95	0.00e+00	1174.00
IUUC-Cne-026986	Cryptococcus neoformans	57.76	0.00e+00	983.00
IUUC-Cme-027219	Cyanidioschyzon merolae	45.72	0.00e+00	781.00
IUUC-Dre-027846	Danio rerio	54.85	0.00e+00	978.00
IUUC-Dor-030462	Dipodomys ordii	53.80	0.00e+00	787.00
IUUC-Dme-031791	Drosophila melanogaster	52.75	0.00e+00	908.00
IUUC-Ete-033166	Echinops telfairi	52.14	0.00e+00	632.00
IUUC-Eca-034180	Equus caballus	53.51	0.00e+00	936.00
IUUC-Eeu-035086	Erinaceus europaeus	43.60	4.00e-103	367.00
IUUC-Fca-036265	Felis catus	54.91	0.00e+00	979.00
IUUC-Fal-037202	Ficedula albicollis	54.79	0.00e+00	933.00
IUUC-Fox-037711	Fusarium oxysporum	77.23	0.00e+00	1209.00
IUUC-Fso-038268	Fusarium solani	77.02	0.00e+00	1208.00
IUUC-Gmo-039046	Gadus morhua	54.57	0.00e+00	964.00
IUUC-Ggr-039863	Gaeumannomyces graminis	78.48	0.00e+00	1258.00
IUUC-Gga-041112	Gallus gallus	55.09	0.00e+00	979.00
IUUC-Gac-041733	Gasterosteus aculeatus	54.72	0.00e+00	942.00
IUUC-Gma-044333	Glycine max	52.80	0.00e+00	905.00
IUUC-Ggo-044984	Gorilla gorilla	54.91	0.00e+00	980.00
IUUC-Hsa-046698	Homo sapiens	54.91	0.00e+00	980.00
IUUC-Hvu-047669	Hordeum vulgare	60.45	4.00e-140	489.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	54.91	0.00e+00	978.00
IUUC-Kpa-049265	Komagataella pastoris	54.32	0.00e+00	966.00
IUUC-Lch-050473	Latimeria chalumnae	55.09	0.00e+00	971.00
IUUC-Lpe-051579	Leersia perrieri	52.03	0.00e+00	882.00
IUUC-Loc-052675	Lepisosteus oculatus	55.19	0.00e+00	977.00
IUUC-Lma-053218	Leptosphaeria maculans	74.97	0.00e+00	1268.00
IUUC-Laf-053757	Loxodonta africana	54.66	0.00e+00	972.00
IUUC-Mcc-054859	Macaca mulatta	54.91	0.00e+00	981.00
IUUC-Meu-056174	Macropus eugenii	46.80	2.00e-90	325.00
IUUC-Mor-057264	Magnaporthe oryzae	78.86	0.00e+00	1245.00
IUUC-Mpo-057538	Magnaporthe poae	78.61	0.00e+00	1290.00
IUUC-Mtr-058310	Medicago truncatula	52.62	0.00e+00	902.00
IUUC-Mla-058937	Melampsora laricipopulina	57.21	0.00e+00	969.00
IUUC-Mga-059875	Meleagris gallopavo	54.96	0.00e+00	974.00
IUUC-Mvi-060240	Microbotryum violaceum	57.47	0.00e+00	993.00
IUUC-Mmr-061261	Microcebus murinus	54.91	0.00e+00	980.00
IUUC-Mdo-062076	Monodelphis domestica	55.21	0.00e+00	981.00
IUUC-Mmu-063324	Mus musculus	55.03	0.00e+00	983.00
IUUC-Mac-064636	Musa acuminata	51.06	0.00e+00	887.00
IUUC-Mpu-065961	Mustela putorius furo	55.03	0.00e+00	983.00
IUUC-Mlu-067059	Myotis lucifugus	54.12	0.00e+00	955.00
IUUC-Nfi-068277	Neosartorya fischeri	77.76	0.00e+00	1326.00
IUUC-Ncr-068659	Neurospora crassa	74.52	0.00e+00	1291.00
IUUC-Nle-069034	Nomascus leucogenys	54.91	0.00e+00	981.00
IUUC-Opr-070334	Ochotona princeps	56.74	0.00e+00	917.00
IUUC-Ont-071563	Oreochromis niloticus	55.21	0.00e+00	973.00
IUUC-Oan-073416	Ornithorhynchus anatinus	55.46	0.00e+00	937.00
IUUC-Ocu-074522	Oryctolagus cuniculus	54.67	0.00e+00	974.00
IUUC-Oba-075760	Oryza barthii	50.79	0.00e+00	870.00
IUUC-Obr-076201	Oryza brachyantha	52.32	0.00e+00	884.00
IUUC-Ogl-077450	Oryza glaberrima	51.40	0.00e+00	892.00
IUUC-Ogu-078994	Oryza glumaepatula	50.79	0.00e+00	869.00
IUUC-Oin-079856	Oryza indica	51.85	0.00e+00	870.00
IUUC-Olo-080731	Oryza longistaminata	51.38	0.00e+00	857.00
IUUC-Ome-081554	Oryza meridionalis	48.78	0.00e+00	805.00
IUUC-Oni-082324	Oryza nivara	50.79	0.00e+00	868.00
IUUC-Opu-083400	Oryza punctata	49.94	0.00e+00	854.00
IUUC-Oru-084829	Oryza rufipogon	50.79	0.00e+00	868.00
IUUC-Osa-086026	Oryza sativa	51.70	0.00e+00	897.00
IUUC-Ola-087245	Oryzias latipes	54.84	0.00e+00	976.00
IUUC-Olu-087655	Ostreococcus lucimarinus	52.46	0.00e+00	891.00
IUUC-Oga-088163	Otolemur garnettii	53.20	0.00e+00	937.00
IUUC-Oar-089842	Ovis aries	54.91	0.00e+00	980.00
IUUC-Ptr-090501	Pan troglodytes	54.91	0.00e+00	981.00
IUUC-Pan-092011	Papio anubis	54.91	0.00e+00	981.00
IUUC-Psi-093308	Pelodiscus sinensis	54.79	0.00e+00	979.00
IUUC-Pma-094695	Petromyzon marinus	54.87	0.00e+00	904.00
IUUC-Pno-094785	Phaeosphaeria nodorum	82.13	2.00e-146	510.00
IUUC-Ppa-095638	Physcomitrella patens	53.14	0.00e+00	904.00
IUUC-Pfo-096587	Poecilia formosa	54.96	0.00e+00	975.00
IUUC-Pab-097926	Pongo abelii	53.13	0.00e+00	901.00
IUUC-Pop-099634	Populus trichocarpa	53.21	0.00e+00	908.00
IUUC-Pca-100965	Procavia capensis	53.70	0.00e+00	941.00
IUUC-Ppe-101470	Prunus persica	53.23	0.00e+00	910.00
IUUC-Pva-102451	Pteropus vampyrus	53.06	0.00e+00	773.00
IUUC-Pgr-103453	Puccinia graminis	57.49	0.00e+00	996.00
IUUC-Ptt-103868	Puccinia triticina	57.37	0.00e+00	991.00
IUUC-Pte-104274	Pyrenophora teres	77.76	0.00e+00	1316.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	76.60	0.00e+00	1253.00
IUUC-Rno-105979	Rattus norvegicus	47.63	0.00e+00	735.00
IUUC-Sce-106269	Saccharomyces cerevisiae	49.82	0.00e+00	857.00
IUUC-Sha-106905	Sarcophilus harrisii	55.21	0.00e+00	982.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	53.02	0.00e+00	883.00
IUUC-Spo-108299	Schizosaccharomyces pombe	52.32	0.00e+00	919.00
IUUC-Smo-108695	Selaginella moellendorffii	51.64	0.00e+00	890.00
IUUC-Sit-110239	Setaria italica	51.64	0.00e+00	896.00
IUUC-Sly-111775	Solanum lycopersicum	53.51	0.00e+00	907.00
IUUC-Stu-112906	Solanum tuberosum	52.49	0.00e+00	816.00
IUUC-Sar-113472	Sorex araneus	52.72	0.00e+00	707.00
IUUC-Sbi-113886	Sorghum bicolor	52.20	0.00e+00	899.00
IUUC-Sre-115040	Sporisorium reilianum	56.19	0.00e+00	966.00
IUUC-Ssc-115593	Sus scrofa	54.79	0.00e+00	979.00
IUUC-Tgu-117239	Taeniopygia guttata	55.19	0.00e+00	977.00
IUUC-Tru-118025	Takifugu rubripes	54.71	0.00e+00	969.00
IUUC-Tsy-118824	Tarsius syrichta	51.42	0.00e+00	706.00
IUUC-Tni-120142	Tetraodon nigroviridis	54.66	0.00e+00	965.00
IUUC-Tca-121613	Theobroma cacao	53.85	0.00e+00	914.00
IUUC-Tre-122072	Trichoderma reesei	76.03	0.00e+00	1281.00
IUUC-Tvi-122546	Trichoderma virens	76.37	0.00e+00	1281.00
IUUC-Tae-125292	Triticum aestivum	51.64	0.00e+00	892.00
IUUC-Tur-126283	Triticum urartu	45.50	0.00e+00	753.00
IUUC-Tme-127041	Tuber melanosporum	73.16	0.00e+00	1285.00
IUUC-Tbe-127770	Tupaia belangeri	55.89	0.00e+00	817.00
IUUC-Ttr-129294	Tursiops truncatus	54.79	0.00e+00	977.00
IUUC-Uma-129351	Ustilago maydis	55.29	0.00e+00	972.00
IUUC-Vda-129716	Verticillium dahliae	77.75	0.00e+00	1329.00
IUUC-Vpa-130037	Vicugna pacos	45.26	2.00e-112	398.00
IUUC-Vvi-131689	Vitis vinifera	53.72	0.00e+00	911.00
IUUC-Xtr-132633	Xenopus tropicalis	55.68	0.00e+00	979.00
IUUC-Xma-133347	Xiphophorus maculatus	54.84	0.00e+00	974.00
IUUC-Yli-134455	Yarrowia lipolytica	54.93	0.00e+00	941.00
IUUC-Zma-135867	Zea mays	52.55	0.00e+00	912.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence