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Tag Content
UUCD2 ID IUUC-Pab-097926
UUCD1 version UUC-PoA-00591
Ensembl Protein ID ENSPPYP00000015835.1
UniProt Accession H2PBL1; H2PBL1_PONAB
Genbank Protein ID ENSPPYP00000015835
Protein Name Coatomer subunit beta'
Genbank Nucleotide ID ABGA01158023
Gene Name COPB2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000014155.1 ENSPPYT00000016460.1 ENSPPYP00000015835.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.50e-33 113.5 186 227
UBD/Beta-Prp 5.40e-69 232.7 13 295
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 186  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 227
           8*********9999778****************999988875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++      +tg++D+ i+v++++t + vh +++h
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKIgknRDLTGADDMQIRVFNYNTLERVHMFEAH 101
           67899************************************************7764344489************************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtd 181
           +d++++++++p++ ++++ s+d  i++wd+++++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++
   Q: 102  SDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEK 189
           **********************************9999**********************************************9.*** PP
   S: 182  svyslsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvi 268
            v+++++ s g  ++l+sg++d+ vk+wd+q+++cv+tl+gh +nv++  f+p+  ++++gs+Dg++riW + +  l +tl++  ++v+
   Q: 190  GVNCIDYYSGGdkPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVW 278
           ******8887777**************************************************************************** PP
   S: 269  svavlsfgdnvlvlgse 285
           +va l+ ++nv +  +e
   Q: 279  CVASLRGSNNVALGYDE 295
           ****9999998854444 PP
   
Organism Pongo abelii
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MPLRLDIKRK LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RAAKFVARKI GKNRDLTGAD DMQIRVFNYN TLERVHMFEA HSDYIRCIAV HPTQPFILTS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-097926|E3,WD_repeat;UBD,Beta-Prp|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTGGATCGG TGGGTTTCTC TCAGGGCCTG AGTAGCCGGT GACAAACGAG GGTTCCCGGG 60
ATCGGACCGA CACAGCCATG GTAGGTCCAA AACCCGTAGA AGGGAGCGGG GTCCCATAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-097926|E3,WD_repeat;UBD,Beta-Prp|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:1901998--P:toxin transport
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 51.01 0.00e+00 874.00
IUUC-Aml-002154 Ailuropoda melanoleuca 96.04 0.00e+00 1731.00
IUUC-Atr-003090 Amborella trichopoda 57.85 0.00e+00 1016.00
IUUC-Apl-003976 Anas platyrhynchos 92.54 0.00e+00 1635.00
IUUC-Aca-004301 Anolis carolinensis 91.58 0.00e+00 1625.00
IUUC-Aly-006508 Arabidopsis lyrata 59.17 0.00e+00 1019.00
IUUC-Ath-007630 Arabidopsis thaliana 59.24 0.00e+00 1032.00
IUUC-Ago-007914 Ashbya gossypii 44.46 0.00e+00 707.00
IUUC-Acl-008237 Aspergillus clavatus 54.95 0.00e+00 892.00
IUUC-Afl-008535 Aspergillus flavus 54.85 0.00e+00 842.00
IUUC-Afu-008845 Aspergillus fumigatus 53.08 0.00e+00 869.00
IUUC-Ani-009135 Aspergillus nidulans 53.89 0.00e+00 853.00
IUUC-Ang-009654 Aspergillus niger 57.27 0.00e+00 808.00
IUUC-Aor-009939 Aspergillus oryzae 52.63 0.00e+00 899.00
IUUC-Ate-010355 Aspergillus terreus 52.61 0.00e+00 856.00
IUUC-Ame-010922 Astyanax mexicanus 82.14 0.00e+00 1401.00
IUUC-Bgr-012249 Blumeria graminis 52.77 0.00e+00 857.00
IUUC-Bta-013579 Bos taurus 96.23 0.00e+00 1408.00
IUUC-Bci-013866 Botrytis cinerea 54.10 0.00e+00 858.00
IUUC-Bdi-015046 Brachypodium distachyon 60.29 0.00e+00 1036.00
IUUC-Bol-016271 Brassica oleracea 59.29 0.00e+00 1034.00
IUUC-Bra-016617 Brassica rapa 58.93 0.00e+00 1009.00
IUUC-Cel-018387 Caenorhabditis elegans 62.90 0.00e+00 1104.00
IUUC-Cja-019145 Callithrix jacchus 97.04 0.00e+00 1748.00
IUUC-Cfa-020564 Canis familiaris 96.71 0.00e+00 1737.00
IUUC-Cpo-022201 Cavia porcellus 94.73 0.00e+00 1712.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 56.92 0.00e+00 923.00
IUUC-Csa-023383 Chlorocebus sabaeus 95.79 0.00e+00 1134.00
IUUC-Cho-024454 Choloepus hoffmanni 90.24 0.00e+00 1350.00
IUUC-Cin-025681 Ciona intestinalis 73.65 0.00e+00 1281.00
IUUC-Csv-026012 Ciona savignyi 74.56 0.00e+00 1253.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 50.49 0.00e+00 773.00
IUUC-Cne-026986 Cryptococcus neoformans 50.66 0.00e+00 858.00
IUUC-Cme-027219 Cyanidioschyzon merolae 45.46 0.00e+00 784.00
IUUC-Dre-027846 Danio rerio 91.06 0.00e+00 1581.00
IUUC-Dor-030462 Dipodomys ordii 90.27 0.00e+00 1208.00
IUUC-Dse-031268 Dothistroma septosporum 53.13 0.00e+00 880.00
IUUC-Dme-031791 Drosophila melanogaster 70.49 0.00e+00 1191.00
IUUC-Ete-033166 Echinops telfairi 86.25 0.00e+00 976.00
IUUC-Eca-034180 Equus caballus 93.88 0.00e+00 1669.00
IUUC-Eeu-035086 Erinaceus europaeus 85.40 0.00e+00 825.00
IUUC-Fca-036265 Felis catus 96.38 0.00e+00 1728.00
IUUC-Fal-037202 Ficedula albicollis 92.60 0.00e+00 1572.00
IUUC-Fox-037711 Fusarium oxysporum 54.16 0.00e+00 827.00
IUUC-Fso-038268 Fusarium solani 54.18 0.00e+00 825.00
IUUC-Gmo-039046 Gadus morhua 90.22 0.00e+00 1560.00
IUUC-Ggr-039863 Gaeumannomyces graminis 53.73 0.00e+00 835.00
IUUC-Gga-041112 Gallus gallus 93.08 0.00e+00 1636.00
IUUC-Gac-041733 Gasterosteus aculeatus 90.00 0.00e+00 1524.00
IUUC-Gma-042910 Glycine max 60.12 0.00e+00 1047.00
IUUC-Ggo-044984 Gorilla gorilla 96.82 0.00e+00 1743.00
IUUC-Hsa-046698 Homo sapiens 96.93 0.00e+00 1745.00
IUUC-Hvu-047669 Hordeum vulgare 69.47 8.00e-165 572.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 94.17 0.00e+00 1684.00
IUUC-Kpa-049265 Komagataella pastoris 48.01 0.00e+00 800.00
IUUC-Lch-050473 Latimeria chalumnae 88.53 0.00e+00 1622.00
IUUC-Lpe-051579 Leersia perrieri 59.55 0.00e+00 1025.00
IUUC-Loc-052675 Lepisosteus oculatus 91.72 0.00e+00 1603.00
IUUC-Lma-053218 Leptosphaeria maculans 53.48 0.00e+00 867.00
IUUC-Laf-053757 Loxodonta africana 95.83 0.00e+00 1727.00
IUUC-Mcc-054859 Macaca mulatta 97.15 0.00e+00 1749.00
IUUC-Meu-056174 Macropus eugenii 91.43 0.00e+00 675.00
IUUC-Mor-057264 Magnaporthe oryzae 53.71 0.00e+00 825.00
IUUC-Mpo-057538 Magnaporthe poae 54.10 0.00e+00 848.00
IUUC-Mtr-058310 Medicago truncatula 60.86 0.00e+00 1055.00
IUUC-Mla-058937 Melampsora laricipopulina 52.14 0.00e+00 852.00
IUUC-Mga-059875 Meleagris gallopavo 92.87 0.00e+00 1632.00
IUUC-Mvi-060240 Microbotryum violaceum 50.99 0.00e+00 856.00
IUUC-Mmr-061261 Microcebus murinus 96.49 0.00e+00 1738.00
IUUC-Mdo-062076 Monodelphis domestica 92.91 0.00e+00 1662.00
IUUC-Mmu-063324 Mus musculus 95.60 0.00e+00 1721.00
IUUC-Mac-064636 Musa acuminata 58.91 0.00e+00 1016.00
IUUC-Mpu-065961 Mustela putorius furo 96.38 0.00e+00 1730.00
IUUC-Mlu-067059 Myotis lucifugus 95.31 0.00e+00 1654.00
IUUC-Nfi-068277 Neosartorya fischeri 52.79 0.00e+00 858.00
IUUC-Ncr-068659 Neurospora crassa 51.46 0.00e+00 843.00
IUUC-Nle-069034 Nomascus leucogenys 97.15 0.00e+00 1748.00
IUUC-Opr-070334 Ochotona princeps 96.07 0.00e+00 1453.00
IUUC-Ont-071563 Oreochromis niloticus 85.47 0.00e+00 1579.00
IUUC-Oan-073416 Ornithorhynchus anatinus 94.92 0.00e+00 1565.00
IUUC-Ocu-074522 Oryctolagus cuniculus 96.05 0.00e+00 1729.00
IUUC-Oba-075760 Oryza barthii 57.99 0.00e+00 1008.00
IUUC-Obr-076201 Oryza brachyantha 59.88 0.00e+00 1029.00
IUUC-Ogl-077450 Oryza glaberrima 59.17 0.00e+00 1035.00
IUUC-Ogu-078994 Oryza glumaepatula 57.99 0.00e+00 1006.00
IUUC-Oin-079856 Oryza indica 59.09 0.00e+00 1013.00
IUUC-Olo-080731 Oryza longistaminata 57.31 0.00e+00 991.00
IUUC-Ome-081554 Oryza meridionalis 55.90 0.00e+00 935.00
IUUC-Oni-082324 Oryza nivara 57.99 0.00e+00 1007.00
IUUC-Opu-083400 Oryza punctata 57.19 0.00e+00 1001.00
IUUC-Oru-084829 Oryza rufipogon 57.99 0.00e+00 1007.00
IUUC-Osa-086026 Oryza sativa 59.17 0.00e+00 1038.00
IUUC-Ola-087245 Oryzias latipes 85.92 0.00e+00 1585.00
IUUC-Olu-087655 Ostreococcus lucimarinus 59.11 0.00e+00 1000.00
IUUC-Oga-088163 Otolemur garnettii 93.09 0.00e+00 1657.00
IUUC-Oar-089842 Ovis aries 96.14 0.00e+00 1717.00
IUUC-Ptr-090501 Pan troglodytes 97.04 0.00e+00 1745.00
IUUC-Pan-092011 Papio anubis 97.04 0.00e+00 1747.00
IUUC-Psi-093308 Pelodiscus sinensis 94.94 0.00e+00 1639.00
IUUC-Pma-094695 Petromyzon marinus 78.79 0.00e+00 1353.00
IUUC-Pno-094785 Phaeosphaeria nodorum 62.41 1.00e-112 400.00
IUUC-Ppa-095911 Physcomitrella patens 60.78 0.00e+00 1060.00
IUUC-Pfo-096587 Poecilia formosa 84.19 0.00e+00 1583.00
IUUC-Pop-099634 Populus trichocarpa 60.41 0.00e+00 1031.00
IUUC-Pca-100965 Procavia capensis 94.51 0.00e+00 1675.00
IUUC-Ppe-101470 Prunus persica 60.12 0.00e+00 1044.00
IUUC-Pva-102451 Pteropus vampyrus 89.67 0.00e+00 1203.00
IUUC-Pgr-103453 Puccinia graminis 52.85 0.00e+00 866.00
IUUC-Ptt-103868 Puccinia triticina 52.85 0.00e+00 863.00
IUUC-Pte-104274 Pyrenophora teres 54.14 0.00e+00 889.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 53.43 0.00e+00 837.00
IUUC-Rno-105979 Rattus norvegicus 82.16 0.00e+00 1204.00
IUUC-Sce-106269 Saccharomyces cerevisiae 46.62 0.00e+00 729.00
IUUC-Sha-106905 Sarcophilus harrisii 93.92 0.00e+00 1661.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 46.61 0.00e+00 771.00
IUUC-Spo-108299 Schizosaccharomyces pombe 46.48 0.00e+00 775.00
IUUC-Smo-108695 Selaginella moellendorffii 60.25 0.00e+00 1005.00
IUUC-Sit-110692 Setaria italica 60.36 0.00e+00 1035.00
IUUC-Sly-111525 Solanum lycopersicum 60.40 0.00e+00 1043.00
IUUC-Stu-112906 Solanum tuberosum 60.63 0.00e+00 917.00
IUUC-Sar-113472 Sorex araneus 88.41 0.00e+00 1093.00
IUUC-Sbi-114052 Sorghum bicolor 61.55 0.00e+00 1042.00
IUUC-Sre-115040 Sporisorium reilianum 51.21 0.00e+00 852.00
IUUC-Ssc-115593 Sus scrofa 96.27 0.00e+00 1735.00
IUUC-Tgu-117239 Taeniopygia guttata 92.84 0.00e+00 1632.00
IUUC-Tru-118025 Takifugu rubripes 90.28 0.00e+00 1570.00
IUUC-Tsy-118824 Tarsius syrichta 88.27 0.00e+00 1121.00
IUUC-Tni-120142 Tetraodon nigroviridis 88.22 0.00e+00 1562.00
IUUC-Tca-121613 Theobroma cacao 58.14 0.00e+00 1044.00
IUUC-Tre-122072 Trichoderma reesei 53.37 0.00e+00 860.00
IUUC-Tvi-122546 Trichoderma virens 52.63 0.00e+00 854.00
IUUC-Tae-125395 Triticum aestivum 58.51 0.00e+00 1033.00
IUUC-Tur-126283 Triticum urartu 52.05 0.00e+00 875.00
IUUC-Tme-127041 Tuber melanosporum 55.25 0.00e+00 900.00
IUUC-Tbe-127770 Tupaia belangeri 89.51 0.00e+00 1203.00
IUUC-Ttr-129294 Tursiops truncatus 96.38 0.00e+00 1736.00
IUUC-Uma-129351 Ustilago maydis 49.76 0.00e+00 842.00
IUUC-Vda-129716 Verticillium dahliae 53.62 0.00e+00 880.00
IUUC-Vpa-130037 Vicugna pacos 86.63 0.00e+00 860.00
IUUC-Vvi-131689 Vitis vinifera 59.95 0.00e+00 1042.00
IUUC-Xtr-132633 Xenopus tropicalis 91.56 0.00e+00 1597.00
IUUC-Xma-133347 Xiphophorus maculatus 85.67 0.00e+00 1589.00
IUUC-Yli-134455 Yarrowia lipolytica 49.11 0.00e+00 772.00
IUUC-Zma-135706 Zea mays 61.18 0.00e+00 1044.00
Created Date 25-Jun-2017

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