iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002037

Ensembl Protein ID

ENSAMEP00000014211.1

UniProt Accession

G1M4E5; G1M4E5_AILME

Genbank Protein ID

ENSAMEP00000014211

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01011416

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000013477.1	ENSAMET00000014810.1	ENSAMEP00000014211.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	8.10e-25	86.6	465	521

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndsl 57
           +ee+let++vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q++ l+k++++++d++
   Q: 465  QEEDLETMTVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAILLKENNAFEDGG 521
           79****************************************************986 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MSHQPLSCLT EKGDSPNETT GNGPPSLAPP NLDTFTPEEL LQQMKELLIE NHQLKEAMKL 60
NNQAMKGRFE ELSAWTERQK EERLFFETQS KEAKERLMAL SHENEKLKEE LEKLRGKTEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCACC AACCACTTAG CTGCCTGACT GAAAAGGGGG ACAGCCCCAA CGAAACCACG 60
GGAAATGGAC CCCCCAGCCT GGCTCCCCCA AACCTGGACA CGTTCACTCC AGAGGAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003812	Anas platyrhynchos	54.79	2.00e-147	516.00
IUUC-Aca-004625	Anolis carolinensis	53.09	3.00e-138	485.00
IUUC-Aly-005781	Arabidopsis lyrata	55.00	2.30e-02	33.50
IUUC-Ath-007558	Arabidopsis thaliana	32.61	1.40e+00	26.90
IUUC-Ame-011116	Astyanax mexicanus	47.75	4.00e-56	212.00
IUUC-Bta-013240	Bos taurus	82.94	0.00e+00	901.00
IUUC-Cel-018324	Caenorhabditis elegans	45.83	1.50e+00	27.30
IUUC-Cja-019911	Callithrix jacchus	81.61	0.00e+00	835.00
IUUC-Cfa-020330	Canis familiaris	89.53	0.00e+00	915.00
IUUC-Cpo-021753	Cavia porcellus	80.47	0.00e+00	827.00
IUUC-Csa-023662	Chlorocebus sabaeus	83.44	0.00e+00	845.00
IUUC-Cho-024574	Choloepus hoffmanni	67.42	6.00e-126	443.00
IUUC-Dre-027720	Danio rerio	40.21	1.00e-90	327.00
IUUC-Dno-029079	Dasypus novemcinctus	78.72	0.00e+00	772.00
IUUC-Dor-030890	Dipodomys ordii	77.55	0.00e+00	813.00
IUUC-Ete-032568	Echinops telfairi	77.21	0.00e+00	700.00
IUUC-Eca-033528	Equus caballus	85.47	0.00e+00	882.00
IUUC-Eeu-035219	Erinaceus europaeus	73.45	0.00e+00	791.00
IUUC-Fca-035852	Felis catus	88.51	0.00e+00	899.00
IUUC-Fal-036862	Ficedula albicollis	57.69	1.00e-142	499.00
IUUC-Gmo-038735	Gadus morhua	38.42	4.00e-73	268.00
IUUC-Gga-040939	Gallus gallus	54.73	3.00e-145	508.00
IUUC-Gac-041580	Gasterosteus aculeatus	42.62	1.00e-93	337.00
IUUC-Ggo-045034	Gorilla gorilla	73.48	0.00e+00	763.00
IUUC-Hsa-046624	Homo sapiens	81.44	0.00e+00	849.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	74.62	0.00e+00	795.00
IUUC-Lch-049720	Latimeria chalumnae	47.98	3.00e-78	285.00
IUUC-Loc-052185	Lepisosteus oculatus	44.50	2.00e-101	363.00
IUUC-Laf-054079	Loxodonta africana	83.11	0.00e+00	837.00
IUUC-Mcc-055674	Macaca mulatta	84.12	0.00e+00	842.00
IUUC-Meu-056769	Macropus eugenii	84.02	2.00e-71	263.00
IUUC-Mga-060203	Meleagris gallopavo	54.97	9.00e-136	477.00
IUUC-Mmr-061492	Microcebus murinus	82.26	0.00e+00	828.00
IUUC-Mdo-063051	Monodelphis domestica	71.81	0.00e+00	745.00
IUUC-Mmu-063409	Mus musculus	76.73	0.00e+00	834.00
IUUC-Mpu-065907	Mustela putorius furo	86.49	0.00e+00	904.00
IUUC-Mlu-066957	Myotis lucifugus	82.09	0.00e+00	805.00
IUUC-Nle-069973	Nomascus leucogenys	81.61	0.00e+00	845.00
IUUC-Opr-071049	Ochotona princeps	76.85	0.00e+00	728.00
IUUC-Ont-071915	Oreochromis niloticus	42.32	5.00e-90	325.00
IUUC-Oan-072965	Ornithorhynchus anatinus	69.41	0.00e+00	722.00
IUUC-Ocu-074029	Oryctolagus cuniculus	74.00	0.00e+00	672.00
IUUC-Ola-087019	Oryzias latipes	42.68	5.00e-85	308.00
IUUC-Oga-088613	Otolemur garnettii	82.14	0.00e+00	857.00
IUUC-Oar-090386	Ovis aries	82.43	0.00e+00	894.00
IUUC-Ptr-091619	Pan troglodytes	81.27	0.00e+00	845.00
IUUC-Pan-092178	Papio anubis	82.20	0.00e+00	828.00
IUUC-Psi-093214	Pelodiscus sinensis	60.44	2.00e-156	545.00
IUUC-Pfo-096901	Poecilia formosa	40.24	1.00e-81	297.00
IUUC-Pab-097560	Pongo abelii	74.75	0.00e+00	734.00
IUUC-Pca-100853	Procavia capensis	68.29	2.00e-111	396.00
IUUC-Pva-102255	Pteropus vampyrus	83.16	0.00e+00	793.00
IUUC-Rno-105812	Rattus norvegicus	78.41	0.00e+00	843.00
IUUC-Sha-107225	Sarcophilus harrisii	79.62	4.00e-153	534.00
IUUC-Sar-113736	Sorex araneus	72.01	9.00e-129	453.00
IUUC-Ssc-115422	Sus scrofa	84.63	0.00e+00	915.00
IUUC-Tgu-116924	Taeniopygia guttata	56.26	4.00e-144	504.00
IUUC-Tru-117695	Takifugu rubripes	39.34	1.00e-84	306.00
IUUC-Tsy-119090	Tarsius syrichta	74.13	4.00e-133	468.00
IUUC-Tni-120645	Tetraodon nigroviridis	40.93	1.00e-85	310.00
IUUC-Tbe-127970	Tupaia belangeri	71.65	3.00e-136	478.00
IUUC-Ttr-129244	Tursiops truncatus	83.33	0.00e+00	846.00
IUUC-Vpa-130313	Vicugna pacos	81.82	0.00e+00	799.00
IUUC-Xtr-132115	Xenopus tropicalis	43.72	4.00e-94	338.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence