iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007074

UUCD1 version

UUC-ArT-01521

Ensembl Protein ID

AT2G25700.1

UniProt Accession

Q9SL93; ASK3_ARATH

Genbank Protein ID

AAD31370.1; AEC07739.1; AAK96604.1; AAM98112.1

Protein Name

SKP1-like protein 3

Genbank Nucleotide ID

AC006053; CP002685; AY052700; AY139806

Gene Name

ASK3; At2g25700; F3N11.15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G25700	AT2G25700.1	AT2G25700.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/SKP1	SKP1	12169662; 12795696; 16983093

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/SKP1	3.30e-29	101.7	115	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/SKP1

   S: 2    sLLdltcktVadmikgktpeeiRktFnienDftpeEeakvReEnqWA 48
           +LLdltck+Vad+++gktp ++R++Fni+nD+tpeEea+vR+En+WA
   Q: 115  GLLDLTCKAVADQMRGKTPAQMREHFNIKNDYTPEEEAEVRNENRWA 161
           8*********************************************9 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity).

Protein Sequence
(Fasta)

MAETKKMIIL KSSDGESFEV EEAVAVESQT IKHMIEDDCV DNGIPLPNVT GAILAKVIEY 60
CKKHVEAAAE AGGDKDFYGS TENHELKTWD NDFVKVDHPT LFDLLRAANY LNISGLLDLT 120

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Nucleotide Sequence
(Fasta)

ATCACACAAT TCACAATCAA TCGCAGAGCC GATTCTCTTC AAAACTTGTC TAGTCCTTTG 60
TCCTTGTTGC AAACGATGGC AGAAACGAAG AAGATGATCA TCCTCAAGAG CTCCGACGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016897--SKP1
IPR001232--SKP1-like
IPR011333--SKP1/BTB/POZ
IPR016072--Skp1_comp_dimer
IPR016073--Skp1_comp_POZ

Pfam

PF01466--Skp1
PF03931--Skp1_POZ

SMART

SM00512--Skp1

Gene Ontology

GO:0005634--C:nucleus
GO:0016567--P:protein ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT2G25700

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bol-015500	Brassica oleracea	81.13	3.00e-74	269.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence