iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007289

UUCD1 version

UUC-ArT-00085

Ensembl Protein ID

AT3G02260.4

UniProt Accession

Q9SRU2; F4J4S0; BIG_ARATH

Genbank Protein ID

AAM77595.1; AAF02112.1; AEE73785.1

Protein Name

Auxin transport protein BIG; Protein ATTENUATED SHADE AVOIDANCE 1; Protein CORYMBOSA1; Protein DARK OVER-EXPRESSION OF CAB 1; Protein LOW PHOSPHATE-RESISTANT ROOT 1; Protein TRANSPORT INHIBITOR RESPONSE 3; Protein UMBRELLA 1

Genbank Nucleotide ID

AF507018; AC009755; CP002686

Gene Name

BIG; ASA1; CRM1; DOC1; GA6; LPR1; TIR3; UMB1; At3g02260; F14P3.9

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G02260	AT3G02260.4	AT3G02260.4
AT3G02260	AT3G02260.2	AT3G02260.2
AT3G02260	AT3G02260.3	AT3G02260.3
AT3G02260	AT3G02260.1	AT3G02260.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/N-recognin/UBR-box	31.66	0.00e+00	899.00	IUUC-Hsa-046955

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis thaliana

Functional Description
(View)

Required for auxin efflux and polar auxin transport (PAT) influencing auxin-mediated developmental responses (e.g. cell elongation, apical dominance, lateral root production, inflorescence architecture, general growth and development). Controls the elongation of the pedicels and stem internodes through auxin action. Involved in the expression modulation of light-regulated genes. Represses CAB1 and CAB3 genes expression in etiolated seedlings. Confers sensitivity to the auxin transport inhibitors N-1-naphthylphthalamic acid (NPA), 2-carboxyphenyl-3-phenylpropane-l,2-dione (CPD), and methyl-2-chloro-9-hydroxyfluorene-9-carboxylate (CFM). Influences the polarized subcellular distribution of the auxin transporter PIN1 in response to auxin transport inhibitors. Plays a role in the regulation of responses to phytohormones such as auxin, cytokinins, ethylene and gibberellic acid (GA), particularly during light-mediated stimuli (e.g. shade ovoidance, etiolation). Required for pericycle cell activation to form lateral root primordia (LRP) in both high and low phosphate P conditions. Necessary for the plant-growth promotion and lateral root development mediated by the fungus Trichoderma virens.

Protein Sequence
(Fasta)

MADDLANLCR FLFDDTAFPS LSSSASSDLF SRRLRSDDSI KRGLRSFYLL LRWGVAPIGG 60
DDADSSGKLR FETWSDSQLQ ALVSISQAIL LLSRSLLGTD LTLNQGLVDQ LEPIVLGVIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATCGAACTC TTCTTCTTTC GCCTCGCCAG AAATGGCAGA TGACTTGGCG AATCTCTGCC 60
GATTTCTCTT CGACGACACC GCCTTTCCCT CTTTGTCGTC TTCGGCATCT TCAGATCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0927--Auxin signaling pathway
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025704--E3_Ub_ligase_UBR4
IPR015943--WD40/YVTN_repeat-like_dom
IPR017986--WD40_repeat_dom
IPR003126--Znf_UBR
IPR000433--Znf_ZZ

PROSITE

PS51157--ZF_UBR
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF13764--E3_UbLigase_R4
PF00569--ZZ

SMART

SM00396--ZnF_UBR1
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0016020--C:membrane
GO:0009506--C:plasmodesma
GO:0008270--F:zinc ion binding
GO:0009926--P:auxin polar transport
GO:0009734--P:auxin-activated signaling pathway
GO:0048281--P:inflorescence morphogenesis
GO:0010311--P:lateral root formation
GO:0009640--P:photomorphogenesis
GO:0009733--P:response to auxin
GO:0009620--P:response to fungus
GO:0048364--P:root development
GO:0009826--P:unidimensional cell growth

KEGG

ath:AT3G02260

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000915	Aegilops tauschii	56.94	0.00e+00	5251.00
IUUC-Aml-001346	Ailuropoda melanoleuca	34.09	0.00e+00	854.00
IUUC-Atr-002587	Amborella trichopoda	55.61	0.00e+00	4129.00
IUUC-Apl-003678	Anas platyrhynchos	33.84	0.00e+00	846.00
IUUC-Aca-004517	Anolis carolinensis	41.59	7.00e-93	333.00
IUUC-Aly-006117	Arabidopsis lyrata	97.35	0.00e+00	9435.00
IUUC-Ame-011965	Astyanax mexicanus	28.89	3.00e-80	294.00
IUUC-Bta-012498	Bos taurus	33.95	0.00e+00	847.00
IUUC-Bci-013659	Botrytis cinerea	41.38	1.00e-06	48.10
IUUC-Bdi-014555	Brachypodium distachyon	57.69	0.00e+00	5231.00
IUUC-Bol-015522	Brassica oleracea	90.05	0.00e+00	8888.00
IUUC-Bra-017090	Brassica rapa	89.98	0.00e+00	8429.00
IUUC-Cel-018504	Caenorhabditis elegans	25.97	1.00e-47	186.00
IUUC-Cja-018983	Callithrix jacchus	34.17	0.00e+00	853.00
IUUC-Cfa-020612	Canis familiaris	34.07	0.00e+00	855.00
IUUC-Cpo-021700	Cavia porcellus	33.95	0.00e+00	852.00
IUUC-Cre-022861	Chlamydomonas reinhardtii	44.83	4.00e-05	42.40
IUUC-Csa-023771	Chlorocebus sabaeus	34.28	0.00e+00	856.00
IUUC-Cho-024474	Choloepus hoffmanni	38.55	2.00e-107	385.00
IUUC-Cin-025247	Ciona intestinalis	30.63	1.00e-86	314.00
IUUC-Csv-026255	Ciona savignyi	30.75	3.00e-90	325.00
IUUC-Cne-027045	Cryptococcus neoformans	35.21	2.00e-04	41.20
IUUC-Dre-028796	Danio rerio	33.45	0.00e+00	852.00
IUUC-Dno-030056	Dasypus novemcinctus	33.84	0.00e+00	847.00
IUUC-Dor-030711	Dipodomys ordii	35.52	0.00e+00	659.00
IUUC-Dme-032113	Drosophila melanogaster	30.75	0.00e+00	810.00
IUUC-Ete-032334	Echinops telfairi	34.45	0.00e+00	823.00
IUUC-Eca-033327	Equus caballus	34.17	0.00e+00	854.00
IUUC-Eeu-034698	Erinaceus europaeus	31.12	7.00e-64	241.00
IUUC-Fca-035430	Felis catus	33.74	0.00e+00	836.00
IUUC-Fal-037566	Ficedula albicollis	33.84	0.00e+00	851.00
IUUC-Gmo-038674	Gadus morhua	33.16	0.00e+00	829.00
IUUC-Gga-040641	Gallus gallus	33.76	0.00e+00	857.00
IUUC-Gac-041870	Gasterosteus aculeatus	31.29	0.00e+00	951.00
IUUC-Gma-042722	Glycine max	66.07	0.00e+00	6189.00
IUUC-Ggo-045360	Gorilla gorilla	34.17	0.00e+00	853.00
IUUC-Hsa-046955	Homo sapiens	34.17	0.00e+00	853.00
IUUC-Hvu-047255	Hordeum vulgare	57.34	0.00e+00	5234.00
IUUC-Itr-048714	Ictidomys tridecemlineatus	28.61	3.00e-85	310.00
IUUC-Lch-049893	Latimeria chalumnae	32.81	0.00e+00	801.00
IUUC-Lpe-050948	Leersia perrieri	56.81	0.00e+00	4910.00
IUUC-Loc-052019	Lepisosteus oculatus	30.36	0.00e+00	786.00
IUUC-Laf-054238	Loxodonta africana	34.07	0.00e+00	853.00
IUUC-Mcc-054905	Macaca mulatta	34.23	0.00e+00	855.00
IUUC-Meu-056297	Macropus eugenii	32.24	0.00e+00	780.00
IUUC-Mtr-058169	Medicago truncatula	65.54	0.00e+00	6288.00
IUUC-Mla-059147	Melampsora laricipopulina	36.00	1.00e-06	46.60
IUUC-Mga-059621	Meleagris gallopavo	32.12	0.00e+00	922.00
IUUC-Mmr-061395	Microcebus murinus	34.26	0.00e+00	798.00
IUUC-Mdo-063037	Monodelphis domestica	34.01	0.00e+00	865.00
IUUC-Mmu-063200	Mus musculus	33.93	0.00e+00	851.00
IUUC-Mac-065267	Musa acuminata	62.97	0.00e+00	3936.00
IUUC-Mpu-066639	Mustela putorius furo	33.86	0.00e+00	854.00
IUUC-Mlu-067172	Myotis lucifugus	32.37	0.00e+00	921.00
IUUC-Nle-069162	Nomascus leucogenys	34.11	0.00e+00	853.00
IUUC-Opr-070567	Ochotona princeps	33.44	1.00e-149	525.00
IUUC-Ont-072364	Oreochromis niloticus	33.59	0.00e+00	839.00
IUUC-Oan-072804	Ornithorhynchus anatinus	31.68	2.00e-138	486.00
IUUC-Ocu-074637	Oryctolagus cuniculus	34.11	0.00e+00	852.00
IUUC-Oba-075215	Oryza barthii	56.92	0.00e+00	4943.00
IUUC-Obr-076704	Oryza brachyantha	57.25	0.00e+00	5269.00
IUUC-Ogl-077593	Oryza glaberrima	55.48	0.00e+00	4204.00
IUUC-Ogu-078732	Oryza glumaepatula	56.93	0.00e+00	4952.00
IUUC-Oin-079805	Oryza indica	72.88	0.00e+00	2446.00
IUUC-Olo-080261	Oryza longistaminata	57.28	0.00e+00	4974.00
IUUC-Ome-081392	Oryza meridionalis	57.08	0.00e+00	5233.00
IUUC-Oni-082086	Oryza nivara	57.00	0.00e+00	4958.00
IUUC-Opu-083535	Oryza punctata	57.12	0.00e+00	4999.00
IUUC-Oru-084735	Oryza rufipogon	56.98	0.00e+00	4960.00
IUUC-Ola-086799	Oryzias latipes	33.51	0.00e+00	843.00
IUUC-Olu-087777	Ostreococcus lucimarinus	32.72	2.00e-110	394.00
IUUC-Oga-088126	Otolemur garnettii	33.29	1.00e-81	297.00
IUUC-Oar-090428	Ovis aries	33.68	0.00e+00	847.00
IUUC-Ptr-091407	Pan troglodytes	34.17	0.00e+00	853.00
IUUC-Pan-091777	Papio anubis	32.52	0.00e+00	927.00
IUUC-Psi-093587	Pelodiscus sinensis	31.49	0.00e+00	884.00
IUUC-Pma-094248	Petromyzon marinus	36.59	2.00e-10	61.20
IUUC-Ppa-095781	Physcomitrella patens	48.07	0.00e+00	4165.00
IUUC-Pfo-097449	Poecilia formosa	31.89	0.00e+00	845.00
IUUC-Pab-098450	Pongo abelii	34.17	0.00e+00	853.00
IUUC-Pop-100041	Populus trichocarpa	69.22	0.00e+00	6496.00
IUUC-Pca-100663	Procavia capensis	29.79	1.00e-102	370.00
IUUC-Ppe-101386	Prunus persica	68.28	0.00e+00	6448.00
IUUC-Pva-102701	Pteropus vampyrus	31.17	0.00e+00	841.00
IUUC-Rno-105367	Rattus norvegicus	32.28	0.00e+00	917.00
IUUC-Sha-107490	Sarcophilus harrisii	34.07	0.00e+00	867.00
IUUC-Ssl-108622	Sclerotinia sclerotiorum	41.38	2.00e-06	47.80
IUUC-Smo-109103	Selaginella moellendorffii	49.56	0.00e+00	4087.00
IUUC-Sit-110670	Setaria italica	57.78	0.00e+00	5154.00
IUUC-Sly-110952	Solanum lycopersicum	62.77	0.00e+00	5946.00
IUUC-Stu-112624	Solanum tuberosum	73.94	0.00e+00	2168.00
IUUC-Sar-113180	Sorex araneus	30.43	8.00e-133	469.00
IUUC-Sbi-114596	Sorghum bicolor	57.50	0.00e+00	5113.00
IUUC-Ssc-115377	Sus scrofa	34.26	0.00e+00	795.00
IUUC-Tgu-117330	Taeniopygia guttata	33.64	0.00e+00	860.00
IUUC-Tru-117635	Takifugu rubripes	32.05	0.00e+00	830.00
IUUC-Tsy-119551	Tarsius syrichta	35.39	2.00e-122	435.00
IUUC-Tni-119727	Tetraodon nigroviridis	32.19	0.00e+00	838.00
IUUC-Tca-121017	Theobroma cacao	69.95	0.00e+00	6709.00
IUUC-Tae-122892	Triticum aestivum	60.36	3.00e-126	444.00
IUUC-Tur-126292	Triticum urartu	56.94	0.00e+00	5253.00
IUUC-Tbe-127560	Tupaia belangeri	40.30	6.00e-11	62.40
IUUC-Ttr-128332	Tursiops truncatus	34.31	1.00e-136	483.00
IUUC-Vpa-130615	Vicugna pacos	25.17	2.00e-42	169.00
IUUC-Vvi-131435	Vitis vinifera	67.79	0.00e+00	6362.00
IUUC-Xtr-132130	Xenopus tropicalis	31.58	3.00e-151	530.00
IUUC-Xma-133859	Xiphophorus maculatus	31.74	0.00e+00	847.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence