iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006621

UUCD1 version

UUC-ArT-01603

Ensembl Protein ID

AT3G13550.1

UniProt Accession

Q9LJD7; COP10_ARATH

Genbank Protein ID

AAK57749.1; BAB01762.1; AEE75370.1

Protein Name

Constitutive photomorphogenesis protein 10

Genbank Nucleotide ID

AY034618; AP000603; CP002686

Gene Name

COP10; At3g13550; MRP15.21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G13550	AT3G13550.1	AT3G13550.1
AT3G13550	AT3G13550.2	AT3G13550.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	18369404

Classification

Family	E-value	Score	Start	End
E2/UBC	1.10e-41	142.8	40	174

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           R+++e++el+ dpp+ +sa+p+ + +l++w ++i+Gp++tpYegg+F l+i fp+dYPfkPPk+ f t+i+h+nv+++G++ ++il+  + Wspal++
   Q: 40   RIQREMAELNIDPPPDCSAGPKGD-NLYHWIATIIGPSGTPYEGGIFFLDIIFPSDYPFKPPKLVFKTRIYHCNVDTAGDLSVNILR--DSWSPALTI 134
           99**********************.9************************************************************9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++vl +i s++ +p+p sp+   +a+l+ ++re++++ ++
   Q: 135  TKVLQAIRSIFLKPEPYSPALPVIARLYLTDREKHDEVAK 174
           **********************************999876 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis-promoting factors such as HY5, HYH and LAF1. Although strongly related to ubiquitin-conjugating enzyme, it has no catalytic activity by itself due to the absence of the conserved Cys active site at position 120. It can however enhance the activity of E2 conjugating enzymes.

Protein Sequence
(Fasta)

MMTPGGSGRL RPLPTAMYAG YSGTASSWVA KTSVSASGKR IQREMAELNI DPPPDCSAGP 60
KGDNLYHWIA TIIGPSGTPY EGGIFFLDII FPSDYPFKPP KLVFKTRIYH CNVDTAGDLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCGTTTC GAAATCTTTT CCCGATGGAG TGCGAGCGAA ACGATCAAGT GGTGGATTGG 60
ATAAGCAGAG AGTATCGGAA GACGACGACG ACGGGAGATG ATGACACCTG GCGGAAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0607--Phytochrome signaling pathway
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0009585--P:red, far-red light phototransduction
GO:0010099--P:regulation of photomorphogenesis

KEGG

ath:AT3G13550

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000463	Aegilops tauschii	69.44	7.00e-61	228.00
IUUC-Aly-005950	Arabidopsis lyrata	97.25	2.00e-103	367.00
IUUC-Bdi-014747	Brachypodium distachyon	69.44	1.00e-59	221.00
IUUC-Bol-015173	Brassica oleracea	92.31	2.00e-100	357.00
IUUC-Bra-017423	Brassica rapa	92.86	3.00e-100	356.00
IUUC-Cre-022791	Chlamydomonas reinhardtii	60.26	5.00e-57	212.00
IUUC-Cin-025161	Ciona intestinalis	52.56	1.00e-49	188.00
IUUC-Gma-043921	Glycine max	73.79	5.00e-62	229.00
IUUC-Ggo-045068	Gorilla gorilla	57.75	1.00e-50	191.00
IUUC-Lpe-051111	Leersia perrieri	67.86	3.00e-59	222.00
IUUC-Mtr-058214	Medicago truncatula	67.96	1.00e-70	258.00
IUUC-Mac-065206	Musa acuminata	71.94	6.00e-59	218.00
IUUC-Oba-075804	Oryza barthii	72.44	2.00e-57	215.00
IUUC-Obr-076634	Oryza brachyantha	56.55	1.00e-52	198.00
IUUC-Ogl-077145	Oryza glaberrima	70.14	6.00e-61	226.00
IUUC-Oin-080066	Oryza indica	59.41	6.00e-57	213.00
IUUC-Opu-083227	Oryza punctata	70.00	2.00e-60	226.00
IUUC-Osa-086202	Oryza sativa	69.44	3.00e-60	223.00
IUUC-Olu-087783	Ostreococcus lucimarinus	58.99	2.00e-53	200.00
IUUC-Pop-099024	Populus trichocarpa	81.25	3.00e-70	256.00
IUUC-Ppe-101314	Prunus persica	76.55	2.00e-67	247.00
IUUC-Smo-108957	Selaginella moellendorffii	62.34	5.00e-58	215.00
IUUC-Sit-109845	Setaria italica	67.36	6.00e-58	216.00
IUUC-Sly-111200	Solanum lycopersicum	72.22	2.00e-63	234.00
IUUC-Sbi-114236	Sorghum bicolor	65.28	3.00e-57	213.00
IUUC-Tca-121777	Theobroma cacao	80.00	6.00e-69	252.00
IUUC-Tae-123791	Triticum aestivum	69.44	3.00e-59	220.00
IUUC-Vvi-131190	Vitis vinifera	80.00	1.00e-73	268.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence