iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-41	138.5	168	204
UBD/Beta-Prp	8.80e-66	223.0	219	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           gH ++v+++af  s+  +++Gs D tik+WD+ tgvl
   Q: 168  GHLGWVRSVAFdpSNEWFCTGSADRTIKIWDVATGVL 204
           8***********54499******************97 PP

UBD/Beta-Prp

   S: 17   kfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGsh 114
           ++s+  ++++++++d+ +k wd+++ k++rs+ gh  +v+++ ++p+ ++ +tg++D + +vwd++t  ++ +l  h+++v s+   p++  +++Gsh
   Q: 219  AVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVLP-HDSDVFSVLARPTDPQVITGSH 315
           5688999********************************************************************.********************** PP
   S: 115  drtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtg 212
           d+ti+ wdl+ g+ +  t ++h+++v+ +++hp++n +vs+s+D++ + ++l+ g+  + + + + d ++ ++++++g  +v+g+++g + +wd ++g
   Q: 316  DSTIKFWDLRYGKSMA-TITNHKKTVRAMALHPKENDFVSASADNI-KKFSLPKGEFCHNMLSLQRDIINAVAVNEDG-VMVTGGDKGGLWFWDWKSG 410
           ****************.***************************96.55******999999999************98.99***************99 PP
   S: 213  ec 214
           + 
   Q: 411  HN 412
           74 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Pleiotropic regulator.

Protein Sequence
(Fasta)

MTMIALNREV ETQSLKKLSL KSVRRAREIF SPVHGQFPQP DPESKRIRLC HKIQVAFGGV 60
EPASKPTRIA DHNSEKTAPL KALALPGPKG SKELRKSATE KALVVGPTLP PRDLNNTGNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATTCGAGT GTTGGGCTAC GTATAAATAG TGTTCGGGTC GGATAAAATC CTATTTCCCT 60
CTCTTCTCTT CCGTCTTTCT CGTTCTGTTT CTGATTGTTC GTGTAAAACC CTAGAATGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0000398--P:mRNA splicing, via spliceosome

KEGG

ath:AT3G16650

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence