iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009878

Ensembl Protein ID

CAK41287

UniProt Accession

A2R0E9; A2R0E9_ASPNC

Genbank Protein ID

CAK41287.1

Protein Name

Aspergillus niger contig An12c0280, genomic contig

Genbank Nucleotide ID

AM270284

Gene Name

An12g08370

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An12g08370	CAK41287	CAK41287

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.90e-58	196.1	112	567
ULD/UDP/UBQ/UBQ_Other	2.70e-10	39.5	11	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.......kkkeklneenp............kepkgellkslqklfeelwkskkkavsprellkalkkeaee 83
           Gl+NlgNtCY+NS+LQ+L ++pel+++ll+       +         +             + + +l++sl++lf+++ +++++ + p ++l+al+++ ++
   Q: 112  GLQNLGNTCYLNSTLQTLRSVPELQDALLKyrpsggsS-------GGSslsnlsslglggLGASMDLTSSLRDLFKQM-SETQEGFPPLMFLNALRNAFPQ 204
           9*****************************54443331.......22234444445555566777*************.99999***************** PP
   S: 84   fs.......gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs......sreepfld 171
           f        gy+qqDa+E ++++++ql+++l                     ++ e +   + s++++ + g ++s++ c e + +       ++ + f++
   Q: 205  FAqrdrnghGYAQQDAEEAWSQIVSQLRNKL-------------------VVKEGEGDSAAEVSFVDKYMAGGFESTTECDEKAAKEageeptNSSDVFYK 286
           *99****************************...................1223456778999*****************776555411111266677888 PP
   S: 172  lslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts..... 267
           l +++ ++++     l+d + +   ee++e      +++ +++   +k+ ++ +lP++L++h+ Rf +++e++++ ki +kv+fp eLd   fct+     
   Q: 287  LDCHIGKETN----HLHDGIMAGL-EEKIE----KRSSTLDRDAVYTKRSRIARLPKYLTVHFVRFFWKRETQKKAKIMRKVTFPAELDAVDFCTDelkkq 378
           8888888886....5777775444.45666....478899999999**************************************************88888 PP
   S: 268  .......................................................peekqke....................................... 274
                                                                  +     +                                       
   Q: 379  lipvrdkvreirkeevdverarkrqklahrkeeeekkeaesgasmepmqkkkaaeE-----Rkgeskaaekdgdeamtdvfksdadyeaektasilaakke 474
           88888888888888888888888888888777666666666666665555555550.....0555555555555666666666666666666666666666 PP
   S: 275  .................kkkYeLiavvvHsG.slssGHYvayvkn........ekgkWllfdDskVtevkeeevleetg....staYvlfYkr 337
                            +  YeL +v+ H+G s++sGHY+ayvk+        +++kW+ f+D+kVtev+ +++++  g    ++a +l+Y+ 
   Q: 475  lselidpslasdsgvnkTGLYELRGVITHQGaSADSGHYTAYVKKqsssdgasTEDKWWWFNDEKVTEVEGDKIETLAGggesHSALILLYRA 567
           66666666666666666****************************666666665777*******************8889***********85 PP

ULD/UDP/UBQ/UBQ_Other

   S: 9    dgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekksg 75
           +g++++++++ps +  +LK ++++++g+ pe+q++++kG  L+dd +L+++++k+g+t++++ + sg
   Q: 11   QGKRYEVELDPSLNGETLKYQLFSLTGVEPERQKILVKGGQLKDDTPLSSLNAKPGQTFMMMGTPSG 77
           7888999999999999**********************************************99876 PP

Organism

Aspergillus niger

Protein Sequence
(Fasta)

MASIPVVVKH QGKRYEVELD PSLNGETLKY QLFSLTGVEP ERQKILVKGG QLKDDTPLSS 60
LNAKPGQTFM MMGTPSGGQG AGDLGRPKEV VKFLEDMTEA EAARAEGATP AGLQNLGNTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCTA TACCTGGTAA GTATCTTTAG GGCCGTATGC TCCATTCCAC TCTATCTTGT 60
TTCTTCTCCG CTGATCCCAT GACGCAGTTG TTGTAAAGCA CCAGGGCAAA CGCTACGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00240--ubiquitin
PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005838--C:proteasome regulatory particle
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ang:ANI_1_2152104

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	28.50	4.00e-27	114.00
IUUC-Aml-002053	Ailuropoda melanoleuca	37.80	2.00e-65	241.00
IUUC-Atr-002725	Amborella trichopoda	34.40	8.00e-71	259.00
IUUC-Apl-004031	Anas platyrhynchos	34.92	1.00e-77	281.00
IUUC-Aca-004361	Anolis carolinensis	35.64	3.00e-84	303.00
IUUC-Aly-006176	Arabidopsis lyrata	35.40	4.00e-80	290.00
IUUC-Ath-007658	Arabidopsis thaliana	35.51	6.00e-82	296.00
IUUC-Ago-007796	Ashbya gossypii	33.45	6.00e-78	282.00
IUUC-Acl-008258	Aspergillus clavatus	83.57	0.00e+00	870.00
IUUC-Afl-008732	Aspergillus flavus	86.61	0.00e+00	947.00
IUUC-Afu-008755	Aspergillus fumigatus	84.48	0.00e+00	884.00
IUUC-Ani-009148	Aspergillus nidulans	80.94	0.00e+00	875.00
IUUC-Aor-010239	Aspergillus oryzae	86.26	0.00e+00	946.00
IUUC-Ate-010243	Aspergillus terreus	82.23	0.00e+00	911.00
IUUC-Ame-011327	Astyanax mexicanus	37.21	7.00e-16	76.60
IUUC-Bgr-012231	Blumeria graminis	61.70	0.00e+00	685.00
IUUC-Bta-012553	Bos taurus	37.75	4.00e-66	243.00
IUUC-Bci-013606	Botrytis cinerea	65.75	0.00e+00	692.00
IUUC-Bdi-014567	Brachypodium distachyon	44.01	4.00e-74	270.00
IUUC-Bol-015565	Brassica oleracea	37.88	5.00e-87	313.00
IUUC-Bra-017297	Brassica rapa	37.35	1.00e-85	308.00
IUUC-Cel-018140	Caenorhabditis elegans	31.86	2.00e-62	231.00
IUUC-Cja-019516	Callithrix jacchus	37.56	4.00e-66	243.00
IUUC-Cfa-020808	Canis familiaris	38.48	5.00e-67	246.00
IUUC-Cpo-021688	Cavia porcellus	38.21	6.00e-65	239.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	34.16	2.00e-47	181.00
IUUC-Csa-023429	Chlorocebus sabaeus	37.56	6.00e-64	236.00
IUUC-Cho-024347	Choloepus hoffmanni	37.50	4.00e-65	240.00
IUUC-Cin-025198	Ciona intestinalis	37.18	7.00e-52	196.00
IUUC-Csv-026007	Ciona savignyi	36.96	7.00e-58	216.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	60.00	2.00e-175	607.00
IUUC-Cne-026963	Cryptococcus neoformans	36.35	1.00e-81	295.00
IUUC-Cme-027240	Cyanidioschyzon merolae	36.29	3.00e-51	194.00
IUUC-Dre-027647	Danio rerio	36.21	1.00e-84	305.00
IUUC-Dno-029967	Dasypus novemcinctus	37.56	1.00e-63	235.00
IUUC-Dor-030886	Dipodomys ordii	32.29	4.00e-39	154.00
IUUC-Dse-031466	Dothistroma septosporum	57.17	7.00e-155	538.00
IUUC-Dme-032079	Drosophila melanogaster	33.64	9.00e-72	262.00
IUUC-Ete-032351	Echinops telfairi	35.61	5.00e-58	216.00
IUUC-Eca-033461	Equus caballus	38.48	5.00e-71	259.00
IUUC-Eeu-035220	Erinaceus europaeus	32.74	1.00e-38	152.00
IUUC-Fca-036210	Felis catus	38.24	1.00e-66	245.00
IUUC-Fal-037528	Ficedula albicollis	34.74	7.00e-77	279.00
IUUC-Fox-037805	Fusarium oxysporum	61.55	0.00e+00	644.00
IUUC-Fso-038177	Fusarium solani	59.14	0.00e+00	636.00
IUUC-Gmo-038953	Gadus morhua	33.85	6.00e-70	256.00
IUUC-Ggr-039972	Gaeumannomyces graminis	59.45	2.00e-179	620.00
IUUC-Gga-040462	Gallus gallus	33.56	6.00e-69	253.00
IUUC-Gac-041312	Gasterosteus aculeatus	37.68	5.00e-66	243.00
IUUC-Gma-043255	Glycine max	37.61	9.00e-81	292.00
IUUC-Ggo-045458	Gorilla gorilla	35.17	4.00e-44	170.00
IUUC-Hsa-045706	Homo sapiens	37.56	3.00e-64	237.00
IUUC-Hvu-047821	Hordeum vulgare	44.12	7.00e-39	152.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	37.01	3.00e-67	247.00
IUUC-Lch-050464	Latimeria chalumnae	34.68	8.00e-78	282.00
IUUC-Lpe-051419	Leersia perrieri	36.94	5.00e-78	283.00
IUUC-Loc-052732	Lepisosteus oculatus	37.23	2.00e-69	254.00
IUUC-Lma-053177	Leptosphaeria maculans	64.83	0.00e+00	660.00
IUUC-Laf-053822	Loxodonta africana	37.99	2.00e-66	244.00
IUUC-Mcc-055893	Macaca mulatta	37.56	3.00e-64	237.00
IUUC-Meu-056307	Macropus eugenii	36.43	4.00e-60	223.00
IUUC-Mor-057171	Magnaporthe oryzae	57.59	0.00e+00	627.00
IUUC-Mpo-057415	Magnaporthe poae	59.69	4.00e-180	622.00
IUUC-Mtr-057901	Medicago truncatula	36.73	5.00e-83	300.00
IUUC-Mla-058897	Melampsora laricipopulina	39.93	5.00e-95	339.00
IUUC-Mga-060016	Meleagris gallopavo	37.50	4.00e-63	233.00
IUUC-Mvi-060562	Microbotryum violaceum	44.53	2.00e-78	284.00
IUUC-Mmr-060624	Microcebus murinus	38.48	2.00e-70	258.00
IUUC-Mdo-061809	Monodelphis domestica	34.47	3.00e-75	273.00
IUUC-Mmu-063869	Mus musculus	37.99	1.00e-65	241.00
IUUC-Mac-064876	Musa acuminata	35.04	6.00e-66	243.00
IUUC-Mpu-066480	Mustela putorius furo	38.73	1.00e-67	248.00
IUUC-Mlu-067866	Myotis lucifugus	38.73	2.00e-67	248.00
IUUC-Nfi-068393	Neosartorya fischeri	84.48	0.00e+00	905.00
IUUC-Ncr-068815	Neurospora crassa	61.14	0.00e+00	641.00
IUUC-Nle-070121	Nomascus leucogenys	41.56	4.00e-39	153.00
IUUC-Opr-070712	Ochotona princeps	33.62	9.00e-31	126.00
IUUC-Ont-071544	Oreochromis niloticus	38.54	1.00e-65	241.00
IUUC-Oan-073635	Ornithorhynchus anatinus	35.96	2.00e-48	184.00
IUUC-Ocu-074926	Oryctolagus cuniculus	38.01	1.00e-63	235.00
IUUC-Oba-075633	Oryza barthii	43.26	4.00e-69	253.00
IUUC-Obr-076423	Oryza brachyantha	44.42	1.00e-73	268.00
IUUC-Ogl-077913	Oryza glaberrima	44.27	2.00e-74	271.00
IUUC-Ogu-078435	Oryza glumaepatula	43.26	4.00e-69	253.00
IUUC-Oin-080072	Oryza indica	42.86	3.00e-69	254.00
IUUC-Olo-080535	Oryza longistaminata	32.33	4.00e-61	226.00
IUUC-Ome-081309	Oryza meridionalis	43.26	4.00e-69	253.00
IUUC-Oni-083113	Oryza nivara	43.26	4.00e-69	253.00
IUUC-Opu-083168	Oryza punctata	41.86	3.00e-64	237.00
IUUC-Oru-084253	Oryza rufipogon	43.26	4.00e-69	253.00
IUUC-Osa-085554	Oryza sativa	44.27	2.00e-74	271.00
IUUC-Ola-086998	Oryzias latipes	38.29	4.00e-64	237.00
IUUC-Olu-087818	Ostreococcus lucimarinus	31.48	6.00e-57	213.00
IUUC-Oga-088571	Otolemur garnettii	38.05	1.00e-65	242.00
IUUC-Oar-089526	Ovis aries	37.97	4.00e-66	243.00
IUUC-Ptr-091433	Pan troglodytes	37.56	3.00e-64	237.00
IUUC-Pan-091966	Papio anubis	37.56	6.00e-64	236.00
IUUC-Psi-093458	Pelodiscus sinensis	35.12	2.00e-73	268.00
IUUC-Pma-094343	Petromyzon marinus	36.54	2.00e-42	164.00
IUUC-Pno-095109	Phaeosphaeria nodorum	65.64	0.00e+00	682.00
IUUC-Ppa-095756	Physcomitrella patens	36.51	6.00e-88	316.00
IUUC-Pfo-096514	Poecilia formosa	38.04	8.00e-65	239.00
IUUC-Pab-098477	Pongo abelii	35.16	4.00e-53	200.00
IUUC-Pop-099221	Populus trichocarpa	36.31	1.00e-78	285.00
IUUC-Pca-100791	Procavia capensis	34.58	1.00e-27	115.00
IUUC-Ppe-101812	Prunus persica	36.56	3.00e-80	290.00
IUUC-Pva-102462	Pteropus vampyrus	36.26	4.00e-52	196.00
IUUC-Pgr-103623	Puccinia graminis	43.77	6.00e-75	273.00
IUUC-Ptt-103767	Puccinia triticina	36.19	4.00e-86	310.00
IUUC-Pte-104109	Pyrenophora teres	66.67	0.00e+00	690.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	66.50	0.00e+00	678.00
IUUC-Rno-105351	Rattus norvegicus	37.01	4.00e-63	233.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.86	3.00e-71	260.00
IUUC-Sha-107491	Sarcophilus harrisii	34.41	1.00e-71	262.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	41.83	8.00e-80	289.00
IUUC-Spo-108174	Schizosaccharomyces pombe	41.62	2.00e-110	390.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	67.01	0.00e+00	690.00
IUUC-Smo-108805	Selaginella moellendorffii	42.54	1.00e-76	278.00
IUUC-Sit-110361	Setaria italica	43.85	2.00e-76	278.00
IUUC-Sly-110965	Solanum lycopersicum	41.34	7.00e-70	256.00
IUUC-Sar-113355	Sorex araneus	36.26	1.00e-51	195.00
IUUC-Sbi-114778	Sorghum bicolor	44.42	9.00e-75	272.00
IUUC-Sre-115011	Sporisorium reilianum	45.67	5.00e-85	306.00
IUUC-Ssc-116273	Sus scrofa	38.46	2.00e-64	237.00
IUUC-Tgu-117063	Taeniopygia guttata	34.74	8.00e-77	279.00
IUUC-Tru-118381	Takifugu rubripes	33.05	9.00e-77	278.00
IUUC-Tsy-119076	Tarsius syrichta	43.96	1.00e-16	79.00
IUUC-Tni-119941	Tetraodon nigroviridis	38.79	1.00e-68	252.00
IUUC-Tca-121246	Theobroma cacao	36.81	1.00e-81	295.00
IUUC-Tre-121969	Trichoderma reesei	60.03	2.00e-172	597.00
IUUC-Tvi-122543	Trichoderma virens	60.10	0.00e+00	636.00
IUUC-Tae-125744	Triticum aestivum	38.01	2.00e-81	294.00
IUUC-Tur-126128	Triticum urartu	36.24	3.00e-20	91.70
IUUC-Tbe-128030	Tupaia belangeri	37.55	3.00e-40	157.00
IUUC-Ttr-128701	Tursiops truncatus	37.58	5.00e-49	186.00
IUUC-Uma-129657	Ustilago maydis	39.76	3.00e-97	347.00
IUUC-Vda-129723	Verticillium dahliae	58.72	0.00e+00	642.00
IUUC-Vpa-130284	Vicugna pacos	33.67	6.00e-26	110.00
IUUC-Vvi-131037	Vitis vinifera	37.32	5.00e-85	306.00
IUUC-Xtr-132235	Xenopus tropicalis	33.81	2.00e-74	271.00
IUUC-Xma-133840	Xiphophorus maculatus	38.04	6.00e-65	239.00
IUUC-Yli-134453	Yarrowia lipolytica	48.84	1.00e-91	328.00
IUUC-Zma-135791	Zea mays	35.96	1.00e-77	282.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence