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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Dme-032198
UUCD1 version UUC-DrM-00618
Ensembl Protein ID FBpp0075316
UniProt Accession Q9VUR0; UFSP2_DROME
Genbank Protein ID AAF49615.1; AAN71164.1
Protein Name Probable Ufm1-specific protease 2
Genbank Nucleotide ID AE014296; BT001409
Gene Name CG16979; UFSP2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0036512 FBtr0075563 FBpp0075316
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
DUB/ULP 47.29 2.00e-78 291.00 IUUC-Hsa-046929
Active Site
Position(s) Description Evidence
440 N/A {ECO:0000250|UniProtKB:Q99K23}
564 {ECO:0000250|UniProtKB:Q99K23}
566 {ECO:0000250|UniProtKB:Q99K23}
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.
 Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.
Protein Sequence
(Fasta)
MLPKLKISAF LLKRLERTKQ QCSGCLFGVF YGEGTLLLLS FNIESSLGQL NYEQIQHRFP 60
AELDLCGLVK FGGCTDGEAH LNEVIKSVDI TDNPILLQCE LGTLVGLRAS FFVHGKLEEV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-032198|DUB,ULP|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACTCAGTTAT CGATAAAAAA TTGCCAGCTG AGCAACATTT ACTCGGGTGG GTGGCCGTGT 60
TACTTTATTT TATTTTCATA CATTTATCAG AAATATGCTA CCCAAACTAA AAATATCCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-032198|DUB,ULP|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
Interpro

IPR012462--Peptidase_C78_UfSP1/2
Pfam

PF07910--Peptidase_C78
Gene Ontology

GO:0012505--C:endomembrane system
GO:0016790--F:thiolester hydrolase activity
GO:0071567--F:UFM1 hydrolase activity
GO:0006508--P:proteolysis
GO:0030431--P:sleep
KEGG dme:Dmel_CG16979
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000578 Aegilops tauschii 52.36 2.00e-63 235.00
IUUC-Aml-001757 Ailuropoda melanoleuca 46.87 9.00e-86 309.00
IUUC-Atr-002641 Amborella trichopoda 48.06 5.00e-67 248.00
IUUC-Apl-003911 Anas platyrhynchos 41.42 4.00e-79 287.00
IUUC-Aca-005294 Anolis carolinensis 40.42 1.00e-89 322.00
IUUC-Aly-006185 Arabidopsis lyrata 52.83 2.00e-65 242.00
IUUC-Ath-006919 Arabidopsis thaliana 53.27 6.00e-65 241.00
IUUC-Ame-011931 Astyanax mexicanus 46.94 2.00e-86 312.00
IUUC-Bta-012389 Bos taurus 46.99 5.00e-86 310.00
IUUC-Bdi-014306 Brachypodium distachyon 55.85 4.00e-61 228.00
IUUC-Bol-016591 Brassica oleracea 39.37 4.00e-66 244.00
IUUC-Bra-017122 Brassica rapa 37.03 3.00e-59 222.00
IUUC-Cel-018132 Caenorhabditis elegans 50.21 2.00e-71 262.00
IUUC-Cja-019735 Callithrix jacchus 38.05 7.00e-83 300.00
IUUC-Cfa-020814 Canis familiaris 38.36 9.00e-89 319.00
IUUC-Cpo-021576 Cavia porcellus 47.29 8.00e-87 313.00
IUUC-Cre-022668 Chlamydomonas reinhardtii 53.33 2.00e-57 214.00
IUUC-Csa-023368 Chlorocebus sabaeus 46.69 2.00e-84 305.00
IUUC-Cho-024731 Choloepus hoffmanni 42.09 1.00e-73 269.00
IUUC-Cin-025359 Ciona intestinalis 46.69 7.00e-88 317.00
IUUC-Csv-025886 Ciona savignyi 60.49 2.00e-73 267.00
IUUC-Dre-027673 Danio rerio 38.73 2.00e-88 318.00
IUUC-Dno-030101 Dasypus novemcinctus 47.16 5.00e-88 317.00
IUUC-Dor-030612 Dipodomys ordii 47.45 6.00e-84 303.00
IUUC-Ete-032738 Echinops telfairi 63.10 5.00e-71 261.00
IUUC-Eca-034093 Equus caballus 47.89 1.00e-86 312.00
IUUC-Eeu-034624 Erinaceus europaeus 46.39 3.00e-84 304.00
IUUC-Fca-035542 Felis catus 46.57 2.00e-85 308.00
IUUC-Fal-036770 Ficedula albicollis 49.36 3.00e-86 311.00
IUUC-Gmo-039601 Gadus morhua 38.89 2.00e-84 305.00
IUUC-Gga-040670 Gallus gallus 46.20 2.00e-90 325.00
IUUC-Gac-042013 Gasterosteus aculeatus 44.38 9.00e-85 306.00
IUUC-Gma-043320 Glycine max 47.02 2.00e-72 265.00
IUUC-Ggo-045051 Gorilla gorilla 47.29 7.00e-86 310.00
IUUC-Hsa-046929 Homo sapiens 47.29 7.00e-86 310.00
IUUC-Itr-047967 Ictidomys tridecemlineatus 38.32 3.00e-86 311.00
IUUC-Lch-049884 Latimeria chalumnae 39.75 4.00e-87 314.00
IUUC-Lpe-051425 Leersia perrieri 53.30 2.00e-64 239.00
IUUC-Loc-052568 Lepisosteus oculatus 52.98 4.00e-89 320.00
IUUC-Laf-053435 Loxodonta africana 44.99 3.00e-86 311.00
IUUC-Mcc-055106 Macaca mulatta 46.69 1.00e-84 306.00
IUUC-Mtr-057740 Medicago truncatula 46.48 2.00e-70 259.00
IUUC-Mga-060094 Meleagris gallopavo 47.95 1.00e-89 322.00
IUUC-Mmr-061634 Microcebus murinus 47.89 5.00e-87 313.00
IUUC-Mdo-062862 Monodelphis domestica 48.69 5.00e-82 297.00
IUUC-Mmu-063729 Mus musculus 47.02 1.00e-85 309.00
IUUC-Mac-065086 Musa acuminata 47.54 2.00e-65 242.00
IUUC-Mpu-066461 Mustela putorius furo 47.46 8.00e-86 310.00
IUUC-Mlu-067443 Myotis lucifugus 46.71 2.00e-83 302.00
IUUC-Nle-069354 Nomascus leucogenys 47.29 7.00e-86 310.00
IUUC-Opr-070818 Ochotona princeps 57.26 8.00e-78 283.00
IUUC-Ont-072430 Oreochromis niloticus 48.55 4.00e-89 320.00
IUUC-Oan-072972 Ornithorhynchus anatinus 61.46 2.00e-69 254.00
IUUC-Ocu-074052 Oryctolagus cuniculus 37.55 6.00e-86 310.00
IUUC-Oba-075331 Oryza barthii 55.85 4.00e-61 228.00
IUUC-Obr-076810 Oryza brachyantha 52.83 3.00e-64 238.00
IUUC-Ogl-077185 Oryza glaberrima 55.85 4.00e-61 228.00
IUUC-Ogu-078014 Oryza glumaepatula 55.85 3.00e-61 229.00
IUUC-Oin-080170 Oryza indica 55.85 3.00e-61 228.00
IUUC-Olo-080561 Oryza longistaminata 55.85 4.00e-61 228.00
IUUC-Ome-081878 Oryza meridionalis 55.85 3.00e-61 229.00
IUUC-Oni-083106 Oryza nivara 55.85 5.00e-61 228.00
IUUC-Opu-083384 Oryza punctata 52.47 4.00e-65 241.00
IUUC-Oru-085240 Oryza rufipogon 55.85 3.00e-61 228.00
IUUC-Osa-086230 Oryza sativa 55.85 2.00e-61 229.00
IUUC-Ola-087525 Oryzias latipes 44.55 5.00e-79 286.00
IUUC-Oga-088657 Otolemur garnettii 44.72 1.00e-87 315.00
IUUC-Oar-089494 Ovis aries 46.69 5.00e-85 307.00
IUUC-Ptr-091189 Pan troglodytes 47.29 7.00e-86 310.00
IUUC-Pan-092071 Papio anubis 46.99 7.00e-85 306.00
IUUC-Psi-092991 Pelodiscus sinensis 47.43 1.00e-88 319.00
IUUC-Pma-094182 Petromyzon marinus 58.39 7.00e-49 184.00
IUUC-Ppa-095743 Physcomitrella patens 45.69 8.00e-73 267.00
IUUC-Pfo-096271 Poecilia formosa 39.12 9.00e-84 303.00
IUUC-Pab-097928 Pongo abelii 44.61 8.00e-77 280.00
IUUC-Pop-098826 Populus trichocarpa 47.20 5.00e-64 238.00
IUUC-Pca-100279 Procavia capensis 39.25 2.00e-87 315.00
IUUC-Ppe-101401 Prunus persica 45.26 2.00e-66 246.00
IUUC-Pva-102713 Pteropus vampyrus 37.86 3.00e-80 291.00
IUUC-Ptt-103714 Puccinia triticina 28.07 3.10e-01 28.10
IUUC-Rno-105697 Rattus norvegicus 38.54 1.00e-85 309.00
IUUC-Sha-106956 Sarcophilus harrisii 50.81 7.00e-86 310.00
IUUC-Smo-109070 Selaginella moellendorffii 45.18 7.00e-76 277.00
IUUC-Sit-109821 Setaria italica 44.26 8.00e-66 243.00
IUUC-Sly-110903 Solanum lycopersicum 44.41 8.00e-66 244.00
IUUC-Stu-111930 Solanum tuberosum 44.88 5.00e-66 244.00
IUUC-Sar-113264 Sorex araneus 46.99 1.00e-84 306.00
IUUC-Sbi-114732 Sorghum bicolor 46.70 6.00e-49 187.00
IUUC-Ssc-115435 Sus scrofa 45.39 3.00e-71 261.00
IUUC-Tgu-116761 Taeniopygia guttata 57.44 3.00e-79 286.00
IUUC-Tru-118435 Takifugu rubripes 39.22 6.00e-87 313.00
IUUC-Tsy-119445 Tarsius syrichta 44.85 1.00e-75 276.00
IUUC-Tni-119948 Tetraodon nigroviridis 58.62 5.00e-71 259.00
IUUC-Tca-121332 Theobroma cacao 46.50 8.00e-66 244.00
IUUC-Tae-123925 Triticum aestivum 52.36 2.00e-63 236.00
IUUC-Tur-126833 Triticum urartu 51.15 5.00e-61 228.00
IUUC-Tbe-127826 Tupaia belangeri 43.07 4.00e-74 271.00
IUUC-Ttr-129116 Tursiops truncatus 55.00 7.00e-81 293.00
IUUC-Vpa-130588 Vicugna pacos 46.08 3.00e-79 288.00
IUUC-Vvi-130898 Vitis vinifera 47.20 5.00e-66 244.00
IUUC-Xtr-132571 Xenopus tropicalis 43.59 3.00e-80 291.00
IUUC-Xma-133755 Xiphophorus maculatus 40.09 3.00e-84 305.00
Created Date 25-Jun-2017

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