iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G34460	AT4G34460.2	AT4G34460.2
AT4G34460	AT4G34460.4	AT4G34460.4
AT4G34460	AT4G34460.1	AT4G34460.1
AT4G34460	AT4G34460.3	AT4G34460.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-39	132.6	246	284
UBD/Beta-Prp	2.60e-49	168.9	110	370

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v+ ++f +d  ++ +GsdDgt++++D+rtg++l+
   Q: 246  GHEGDVNTVKFfPDgYRFGTGSDDGTCRLYDIRTGHQLQ 284
           8*********9999899******************9987 PP

UBD/Beta-Prp

   S: 55   vtavkfspdgkilvtgseDrtikvwdls.......tgkcvhtlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvv 140
           v ++ fsp+g+  + g+ D +  +++ls       t +  + l+gh  +v ++++ p+   +l++ s d+t  +wd+ tg + +     ++sgh++ v
   Q: 110  VMTCAFSPNGQSVACGGLDSVCSIFSLSstadkdgTVPVSRMLTGHRGYVSCCQYVPNEdAHLITSSGDQTCILWDVTTGLKTSVfggeFQSGHTADV 207
           67899********************99999999999999999***************6659*******************999889999********* PP
   S: 141  ncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfsp 232
            +v++++++ n ++sGs D+t rlWd  +  + +rt+ g h+++v+ ++f ++g ++ +gs+dgt +l+d++tg+ ++ ++ h      +v+s++fs 
   Q: 208  LSVSISGSNpNWFISGSCDSTARLWDTrAASRAVRTFHG-HEGDVNTVKFFPDGYRFGTGSDDGTCRLYDIRTGHQLQVYQPHGdgenGPVTSIAFSV 304
           ***************************556789*****9.************************************99999998777799*******6 PP
   S: 233  nderlvsgs.sDgsiriWdlrsgdllktlqlhn...ssvisvavlsfgdnvlvlgsedskvniwkl 294
            + +l  g  s ++ ++Wd+  g+++  l l++    + is+ +ls +++ l++gs ds+++iw++
   Q: 305  SGRLLFAGYaSNNTCYVWDTLLGEVVLDLGLQQdshRNRISCLGLSADGSALCTGSWDSNLKIWAF 370
           6666655545*******************9999755344444446888****************98 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Together with GCR1 and GPA1, acts as a negative regulator of ABA during seed germination and early seedling development. The heterotrimeric G-protein controls defense responses to necrotrophic and vascular fungi probably by modulating cell wall-related genes expression (e.g. lower xylose content in cell walls); involved in resistance to fungal pathogens such as Alternaria brassicicola and Fusarium oxysporum. Modulates root architecture (e.g. lateral root formation). Acts with XGL3 in the positive regulation of root waving and root skewing. Involved in the asymmetric division of zygote and specification of apical and basal cell lineages (PubMed:27014878).

Protein Sequence
(Fasta)

MSVSELKERH AVATETVNNL RDQLRQRRLQ LLDTDVARYS AAQGRTRVSF GATDLVCCRT 60
LQGHTGKVYS LDWTPERNRI VSASQDGRLI VWNALTSQKT HAIKLPCAWV MTCAFSPNGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGTCCAAAA CCAAAAACAA TCATAGCTCT TAAACGATAT CGTTTAATCA TTGTGAGAGG 60
GTCCACTTTA ATGGGAACAG TCAATGTCTA TTGACCCTCT TCTCTCTCTC TAGCTAGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0938--Abscisic acid signaling pathway
KW-0025--Alternative splicing
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0539--Nucleus
KW-0611--Plant defense
KW-1185--Reference proteome
KW-0677--Repeat
KW-0807--Transducer
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005783--C:endoplasmic reticulum
GO:0005834--C:heterotrimeric G-protein complex
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0003924--F:GTPase activity
GO:0004871--F:signal transducer activity
GO:0009738--P:abscisic acid-activated signaling pathway
GO:0050832--P:defense response to fungus
GO:0009817--P:defense response to fungus, incompatible interaction
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0010154--P:fruit development
GO:0009867--P:jasmonic acid mediated signaling pathway
GO:0048527--P:lateral root development
GO:0009788--P:negative regulation of abscisic acid-activated signaling pathway
GO:1905392--P:plant organ morphogenesis
GO:0072593--P:reactive oxygen species metabolic process
GO:2000280--P:regulation of root development
GO:0009723--P:response to ethylene
GO:0009991--P:response to extracellular stimulus
GO:0048364--P:root development
GO:0009845--P:seed germination

KEGG

ath:AT4G34460

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000161	Aegilops tauschii	74.86	6.00e-143	499.00
IUUC-Aml-002370	Ailuropoda melanoleuca	50.32	5.00e-84	303.00
IUUC-Atr-002610	Amborella trichopoda	79.37	6.00e-171	592.00
IUUC-Apl-004079	Anas platyrhynchos	50.97	1.00e-83	302.00
IUUC-Aca-004539	Anolis carolinensis	50.97	4.00e-82	297.00
IUUC-Aly-006025	Arabidopsis lyrata	99.47	0.00e+00	737.00
IUUC-Ago-007831	Ashbya gossypii	34.25	1.00e-44	173.00
IUUC-Acl-008154	Aspergillus clavatus	53.44	7.00e-92	330.00
IUUC-Afl-008568	Aspergillus flavus	53.53	1.00e-94	338.00
IUUC-Afu-008789	Aspergillus fumigatus	53.44	5.00e-92	330.00
IUUC-Ani-009213	Aspergillus nidulans	53.53	2.00e-93	335.00
IUUC-Ang-009836	Aspergillus niger	53.53	4.00e-94	337.00
IUUC-Aor-010165	Aspergillus oryzae	53.53	1.00e-94	338.00
IUUC-Ate-010520	Aspergillus terreus	44.88	8.00e-74	269.00
IUUC-Ame-011092	Astyanax mexicanus	50.65	1.00e-84	305.00
IUUC-Bgr-012079	Blumeria graminis	52.46	1.00e-88	318.00
IUUC-Bta-012810	Bos taurus	50.97	1.00e-83	302.00
IUUC-Bci-013621	Botrytis cinerea	52.73	4.00e-90	323.00
IUUC-Bdi-014785	Brachypodium distachyon	76.52	2.00e-165	574.00
IUUC-Bol-015657	Brassica oleracea	94.16	0.00e+00	706.00
IUUC-Bra-017618	Brassica rapa	94.43	0.00e+00	709.00
IUUC-Cel-018704	Caenorhabditis elegans	51.92	2.00e-86	311.00
IUUC-Cja-019894	Callithrix jacchus	50.97	3.00e-84	304.00
IUUC-Cfa-020140	Canis familiaris	50.00	3.00e-84	304.00
IUUC-Cpo-021908	Cavia porcellus	50.65	1.00e-83	302.00
IUUC-Csa-023321	Chlorocebus sabaeus	50.65	1.00e-83	302.00
IUUC-Cho-024766	Choloepus hoffmanni	48.44	1.00e-82	298.00
IUUC-Cin-025309	Ciona intestinalis	45.36	4.00e-87	314.00
IUUC-Csv-026258	Ciona savignyi	50.32	1.00e-87	315.00
IUUC-Cgl-026673	Colletotrichum gloeosporioides	52.24	3.00e-91	327.00
IUUC-Cne-026811	Cryptococcus neoformans	51.13	5.00e-88	317.00
IUUC-Dre-027412	Danio rerio	50.65	1.00e-84	305.00
IUUC-Dno-029783	Dasypus novemcinctus	50.65	7.00e-84	303.00
IUUC-Dor-030322	Dipodomys ordii	45.16	1.00e-69	255.00
IUUC-Dse-031388	Dothistroma septosporum	52.41	5.00e-91	327.00
IUUC-Dme-031748	Drosophila melanogaster	49.35	1.00e-81	295.00
IUUC-Ete-032710	Echinops telfairi	49.68	3.00e-82	297.00
IUUC-Eca-034169	Equus caballus	50.97	9.00e-84	302.00
IUUC-Eeu-035079	Erinaceus europaeus	44.09	2.00e-73	268.00
IUUC-Fca-035392	Felis catus	50.65	3.00e-84	304.00
IUUC-Fal-036902	Ficedula albicollis	51.94	1.00e-84	305.00
IUUC-Fox-037946	Fusarium oxysporum	52.56	6.00e-92	330.00
IUUC-Fso-038136	Fusarium solani	52.56	6.00e-92	330.00
IUUC-Gmo-039709	Gadus morhua	50.00	3.00e-84	304.00
IUUC-Ggr-039969	Gaeumannomyces graminis	53.21	2.00e-92	331.00
IUUC-Gga-040655	Gallus gallus	49.10	1.00e-83	302.00
IUUC-Gac-041386	Gasterosteus aculeatus	50.32	1.00e-84	305.00
IUUC-Gma-043322	Glycine max	81.38	3.00e-177	613.00
IUUC-Ggo-045346	Gorilla gorilla	50.65	1.00e-83	302.00
IUUC-Hsa-046203	Homo sapiens	50.65	1.00e-83	302.00
IUUC-Hvu-047596	Hordeum vulgare	76.52	6.00e-165	572.00
IUUC-Itr-048501	Ictidomys tridecemlineatus	51.61	1.00e-83	301.00
IUUC-Kpa-049192	Komagataella pastoris	35.58	9.00e-51	193.00
IUUC-Lch-049422	Latimeria chalumnae	50.00	2.00e-78	285.00
IUUC-Lpe-051040	Leersia perrieri	78.10	6.00e-169	586.00
IUUC-Loc-052939	Lepisosteus oculatus	50.32	2.00e-84	305.00
IUUC-Lma-052985	Leptosphaeria maculans	52.06	7.00e-90	323.00
IUUC-Laf-053616	Loxodonta africana	50.65	9.00e-84	302.00
IUUC-Mcc-055798	Macaca mulatta	50.65	1.00e-83	302.00
IUUC-Meu-056902	Macropus eugenii	50.32	7.00e-83	299.00
IUUC-Mor-057188	Magnaporthe oryzae	52.88	1.00e-91	329.00
IUUC-Mpo-057544	Magnaporthe poae	53.21	2.00e-92	332.00
IUUC-Mtr-058752	Medicago truncatula	80.47	7.00e-176	608.00
IUUC-Mla-059086	Melampsora laricipopulina	53.70	7.00e-91	326.00
IUUC-Mga-059516	Meleagris gallopavo	50.97	2.00e-83	301.00
IUUC-Mvi-060482	Microbotryum violaceum	54.34	2.00e-92	331.00
IUUC-Mmr-061701	Microcebus murinus	51.29	1.00e-84	305.00
IUUC-Mdo-062734	Monodelphis domestica	50.32	7.00e-83	299.00
IUUC-Mmu-063132	Mus musculus	50.32	1.00e-83	302.00
IUUC-Mac-064523	Musa acuminata	77.89	6.00e-162	562.00
IUUC-Mpu-066365	Mustela putorius furo	50.65	1.00e-83	302.00
IUUC-Mlu-067628	Myotis lucifugus	51.94	2.00e-85	308.00
IUUC-Nfi-068332	Neosartorya fischeri	53.44	7.00e-92	330.00
IUUC-Ncr-068650	Neurospora crassa	51.95	5.00e-89	320.00
IUUC-Nle-069612	Nomascus leucogenys	48.44	2.00e-82	298.00
IUUC-Opr-070261	Ochotona princeps	50.97	2.00e-83	301.00
IUUC-Ont-071287	Oreochromis niloticus	50.00	3.00e-84	304.00
IUUC-Oan-072780	Ornithorhynchus anatinus	49.68	6.00e-78	283.00
IUUC-Ocu-074255	Oryctolagus cuniculus	50.97	1.00e-83	302.00
IUUC-Oba-075818	Oryza barthii	74.74	4.00e-164	570.00
IUUC-Obr-076229	Oryza brachyantha	78.39	4.00e-157	547.00
IUUC-Ogl-077730	Oryza glaberrima	77.31	1.00e-167	581.00
IUUC-Ogu-078583	Oryza glumaepatula	75.93	2.00e-121	427.00
IUUC-Oin-079661	Oryza indica	77.04	1.00e-162	564.00
IUUC-Olo-080225	Oryza longistaminata	75.93	2.00e-121	427.00
IUUC-Oni-082161	Oryza nivara	77.31	2.00e-167	581.00
IUUC-Opu-084072	Oryza punctata	77.84	9.00e-169	585.00
IUUC-Oru-084316	Oryza rufipogon	77.31	1.00e-162	564.00
IUUC-Osa-085380	Oryza sativa	77.31	1.00e-162	564.00
IUUC-Ola-087490	Oryzias latipes	49.68	1.00e-83	302.00
IUUC-Oga-088685	Otolemur garnettii	50.97	1.00e-83	302.00
IUUC-Oar-089373	Ovis aries	50.96	1.00e-83	302.00
IUUC-Ptr-091444	Pan troglodytes	50.32	9.00e-83	299.00
IUUC-Pan-092347	Papio anubis	50.65	1.00e-83	302.00
IUUC-Psi-092965	Pelodiscus sinensis	50.65	4.00e-83	300.00
IUUC-Pma-094748	Petromyzon marinus	48.89	1.00e-67	248.00
IUUC-Pno-095135	Phaeosphaeria nodorum	52.06	1.00e-89	322.00
IUUC-Ppa-095726	Physcomitrella patens	59.63	8.00e-113	399.00
IUUC-Pfo-097028	Poecilia formosa	50.97	3.00e-85	307.00
IUUC-Pab-098335	Pongo abelii	50.65	2.00e-83	301.00
IUUC-Pop-099370	Populus trichocarpa	83.60	2.00e-180	624.00
IUUC-Pca-100940	Procavia capensis	50.32	9.00e-83	299.00
IUUC-Ppe-102016	Prunus persica	79.63	4.00e-175	606.00
IUUC-Pva-102666	Pteropus vampyrus	51.29	1.00e-84	305.00
IUUC-Pgr-103321	Puccinia graminis	52.09	5.00e-89	320.00
IUUC-Ptt-103728	Puccinia triticina	52.09	5.00e-89	320.00
IUUC-Pte-104053	Pyrenophora teres	52.06	1.00e-89	322.00
IUUC-Pyt-104426	Pyrenophora triticirepentis	47.50	4.00e-80	290.00
IUUC-Rno-105834	Rattus norvegicus	51.29	1.00e-83	301.00
IUUC-Sce-106298	Saccharomyces cerevisiae	32.63	1.00e-51	196.00
IUUC-Sha-107128	Sarcophilus harrisii	50.97	1.00e-83	302.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.85	5.00e-50	190.00
IUUC-Spo-108352	Schizosaccharomyces pombe	40.45	5.00e-63	233.00
IUUC-Ssl-108539	Sclerotinia sclerotiorum	52.88	1.00e-90	325.00
IUUC-Smo-109652	Selaginella moellendorffii	55.00	5.00e-109	387.00
IUUC-Sit-110441	Setaria italica	77.57	2.00e-168	584.00
IUUC-Sly-111784	Solanum lycopersicum	81.75	9.00e-177	612.00
IUUC-Stu-112400	Solanum tuberosum	82.01	8.00e-178	615.00
IUUC-Sar-113642	Sorex araneus	50.17	2.00e-76	278.00
IUUC-Sbi-114038	Sorghum bicolor	77.04	1.00e-165	574.00
IUUC-Sre-115035	Sporisorium reilianum	52.73	2.00e-91	328.00
IUUC-Ssc-115886	Sus scrofa	50.97	9.00e-84	302.00
IUUC-Tgu-116461	Taeniopygia guttata	52.26	4.00e-85	307.00
IUUC-Tru-117828	Takifugu rubripes	50.32	2.00e-84	304.00
IUUC-Tsy-119354	Tarsius syrichta	48.44	7.00e-83	299.00
IUUC-Tni-120216	Tetraodon nigroviridis	50.65	2.00e-83	301.00
IUUC-Tca-121224	Theobroma cacao	83.33	2.00e-179	620.00
IUUC-Tre-122156	Trichoderma reesei	52.24	2.00e-91	328.00
IUUC-Tvi-122640	Trichoderma virens	52.24	2.00e-91	328.00
IUUC-Tae-125653	Triticum aestivum	77.04	1.00e-165	575.00
IUUC-Tur-126755	Triticum urartu	77.98	6.00e-158	551.00
IUUC-Tme-126886	Tuber melanosporum	54.17	6.00e-94	336.00
IUUC-Tbe-127469	Tupaia belangeri	43.45	1.00e-69	256.00
IUUC-Ttr-128403	Tursiops truncatus	50.32	9.00e-83	299.00
IUUC-Uma-129589	Ustilago maydis	53.70	6.00e-92	330.00
IUUC-Vda-129855	Verticillium dahliae	52.56	5.00e-91	326.00
IUUC-Vpa-130173	Vicugna pacos	41.38	1.00e-52	199.00
IUUC-Vvi-131162	Vitis vinifera	83.07	9.00e-180	622.00
IUUC-Xtr-132928	Xenopus tropicalis	49.68	3.00e-83	301.00
IUUC-Xma-133743	Xiphophorus maculatus	50.97	3.00e-85	307.00
IUUC-Yli-134396	Yarrowia lipolytica	33.92	8.00e-48	183.00
IUUC-Zma-135893	Zea mays	76.52	1.00e-164	571.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence