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Tag Content
UUCD2 ID IUUC-Cin-025790
UUCD1 version UUC-CiI-00572
Ensembl Protein ID ENSCINP00000016116.3
UniProt Accession F6U4V1; F6U4V1_CIOIN
Genbank Protein ID ENSCINP00000016116
Protein Name Uncharacterized protein
Genbank Nucleotide ID EAAA01000262
Gene Name LOC100176463
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCING00000007869.3 ENSCINT00000016116.3 ENSCINP00000016116.3
Status Unreviewed
Classification
Family E-Value Score Start End
E1 3.60e-209 694.9 416 906
Active Site
Position(s) Description Evidence
606 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU10132}
Domain Profile

   E1
   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv..............gsitvvDmdtvevsnlnrqFLfraedvgksKAe 75
           YD+Qi+++G + q+kl+s+++++vGag++GcEllKn+ ++G+              gs+ v+Dmd +e+snlnrqFLfr++dv+k K++
   Q: 416  YDGQIAIFGKDFQRKLSSQRWFVVGAGAIGCELLKNFSMIGLgcklgnlvekedetGSLVVTDMDVIEKSNLNRQFLFRPHDVQKLKSQ 504
           ***************************************************************************************** PP
   S: 76   vaaealkelnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecys 161
           +aa+a+k++np  ++++he+++ +++e+++   Ff+++d+V++aldn++ar +++r+c+++r+pl+esgtlG++G+++v++++ te+ys
   Q: 505  CAADAVKKMNPLARIVSHENRVGPETENVYtddFFENLDGVANALDNVQARIYMDRRCVYYRKPLLESGTLGTKGNIQVVLPYSTESYS 593
           ***************************************************************************************** PP
   S: 162  csddppqktiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeai 238
           +s+dpp+k+iP+ctlk++pna+eht++wa              +n++l +++++ ++ +kl  +e+ +++++v ++l +++++nf++++
   Q: 594  SSQDPPEKSIPICTLKNFPNAIEHTLQWArdefeglfrnsaDTANQYL-TDPKFYDRISKLPGAEPVTTLEAVHNALLKNRPQNFADCV 681
           *************************************99988899999.78889999999***************************** PP
   S: 239  eiavkafakttinsikqllksfecdivtkskspfwv..................................................... 274
           + a+  f++ ++n+ikqll++f++d+ ++s++ fw+                                                     
   Q: 682  QFARLRFQELYHNNIKQLLHNFPPDQKNSSGAMFWSgpkrcphplvfdpentthfgyvlaasnlyatmygmptmtnaeeikkhlgqitv 770
           ***********************************************************************999999988888777755 PP
   S: 275  ...sfcsna.ealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepk 352
              +  + +  ++ + +  + ++       +     ++ l++a+ ++e+ kg  +   +fekddd   ++d++ aa+nlrae+++i+p 
   Q: 771  pefK--TKSgVKIATTDAEANQMNSG----SmddtqFEDLKKAIPTVESFKGFRMLPADFEKDDDTnfHMDFIVAASNLRAENYEISP- 852
           5321..21102222223333333333....134447999*************************************************. PP
   S: 353  ldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           +d+++ k iag+iipaiatt+a v+Gl+++E++K+v+g  k e +kn f+++a+
   Q: 853  ADRHKSKLIAGKIIPAIATTTALVAGLVCLELYKIVQGnkKLESYKNGFVNLAL 906
           **************************************9999*******99875 PP
   
Organism Ciona intestinalis
Protein Sequence
(Fasta)
MDQVQNGDSQ QAIDEGLYSR QLYVLGHDAM KRMGASNILI SGMKGLGIEI AKNVILGGVK 60
AVTLHDEDTA TIEHLSSQYF VSDADIGKNL AEVSAIQVSE LNPYVPVHPY TGKLTEEFLS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cin-025790|E1,E1_ThiF|Ciona intestinalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCACACTCAA TGTGGATTTT GTTGATTATA TTCCTTTGTT CCTGGTTCAG GTATAGTCAG 60
TTATCTGTCT TGTTGAAACA AGTCTATTCT TATTGCACCA CTCTGTCGTG TCGCAAGCGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cin-025790|E1,E1_ThiF|Ciona intestinalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like
PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2
Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys
PRINTS

PR01849--UBIQUITINACT
SMART

SM00985--UBA_e1_C
Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000367 Aegilops tauschii 44.09 0.00e+00 825.00
IUUC-Aml-001311 Ailuropoda melanoleuca 63.29 0.00e+00 1340.00
IUUC-Atr-002684 Amborella trichopoda 44.52 0.00e+00 868.00
IUUC-Apl-004158 Anas platyrhynchos 41.19 0.00e+00 730.00
IUUC-Aca-004620 Anolis carolinensis 63.54 0.00e+00 1345.00
IUUC-Aly-005515 Arabidopsis lyrata 44.34 0.00e+00 881.00
IUUC-Ath-006891 Arabidopsis thaliana 44.57 0.00e+00 880.00
IUUC-Ago-007873 Ashbya gossypii 50.10 0.00e+00 975.00
IUUC-Acl-008181 Aspergillus clavatus 53.35 0.00e+00 1043.00
IUUC-Afl-008455 Aspergillus flavus 53.50 0.00e+00 1009.00
IUUC-Afu-009065 Aspergillus fumigatus 53.71 0.00e+00 1056.00
IUUC-Ani-009371 Aspergillus nidulans 53.15 0.00e+00 1021.00
IUUC-Ang-009737 Aspergillus niger 52.92 0.00e+00 1025.00
IUUC-Aor-010007 Aspergillus oryzae 53.50 0.00e+00 1009.00
IUUC-Ate-010466 Aspergillus terreus 52.69 0.00e+00 1050.00
IUUC-Ame-010933 Astyanax mexicanus 64.99 0.00e+00 1295.00
IUUC-Bgr-012281 Blumeria graminis 51.29 0.00e+00 1036.00
IUUC-Bta-012767 Bos taurus 63.77 0.00e+00 1344.00
IUUC-Bci-013721 Botrytis cinerea 52.86 0.00e+00 993.00
IUUC-Bdi-014843 Brachypodium distachyon 43.42 0.00e+00 830.00
IUUC-Bol-015665 Brassica oleracea 44.06 0.00e+00 863.00
IUUC-Bra-017707 Brassica rapa 44.15 0.00e+00 877.00
IUUC-Cel-018260 Caenorhabditis elegans 49.19 0.00e+00 937.00
IUUC-Cja-019152 Callithrix jacchus 63.28 0.00e+00 1342.00
IUUC-Cfa-020622 Canis familiaris 62.02 0.00e+00 1279.00
IUUC-Cpo-022526 Cavia porcellus 63.18 0.00e+00 1325.00
IUUC-Cre-022702 Chlamydomonas reinhardtii 44.64 0.00e+00 816.00
IUUC-Csa-023780 Chlorocebus sabaeus 63.57 0.00e+00 1348.00
IUUC-Cho-024682 Choloepus hoffmanni 34.75 2.00e-100 359.00
IUUC-Csv-026084 Ciona savignyi 82.73 0.00e+00 1806.00
IUUC-Cgl-026512 Colletotrichum gloeosporioides 52.52 0.00e+00 1073.00
IUUC-Cne-026960 Cryptococcus neoformans 54.40 0.00e+00 1068.00
IUUC-Cme-027290 Cyanidioschyzon merolae 43.23 0.00e+00 806.00
IUUC-Dre-028149 Danio rerio 64.57 0.00e+00 1315.00
IUUC-Dno-028884 Dasypus novemcinctus 63.37 0.00e+00 1340.00
IUUC-Dor-030229 Dipodomys ordii 61.05 0.00e+00 1271.00
IUUC-Dse-031524 Dothistroma septosporum 51.48 0.00e+00 1035.00
IUUC-Dme-032045 Drosophila melanogaster 57.82 0.00e+00 1218.00
IUUC-Ete-032544 Echinops telfairi 62.50 4.00e-151 527.00
IUUC-Eca-033330 Equus caballus 63.47 0.00e+00 1348.00
IUUC-Eeu-034717 Erinaceus europaeus 39.69 6.00e-144 503.00
IUUC-Fca-036255 Felis catus 63.76 0.00e+00 1338.00
IUUC-Fal-037445 Ficedula albicollis 41.54 0.00e+00 767.00
IUUC-Fox-038007 Fusarium oxysporum 50.75 8.00e-155 538.00
IUUC-Fso-038339 Fusarium solani 51.45 0.00e+00 992.00
IUUC-Gmo-039338 Gadus morhua 62.05 0.00e+00 1273.00
IUUC-Ggr-039823 Gaeumannomyces graminis 50.24 0.00e+00 1046.00
IUUC-Gga-040747 Gallus gallus 41.19 0.00e+00 721.00
IUUC-Gac-041773 Gasterosteus aculeatus 61.67 0.00e+00 1247.00
IUUC-Gma-043198 Glycine max 44.72 0.00e+00 864.00
IUUC-Ggo-045336 Gorilla gorilla 63.28 0.00e+00 1328.00
IUUC-Hsa-045982 Homo sapiens 63.28 0.00e+00 1326.00
IUUC-Hvu-047418 Hordeum vulgare 43.75 0.00e+00 847.00
IUUC-Itr-048460 Ictidomys tridecemlineatus 63.66 0.00e+00 1345.00
IUUC-Kpa-049112 Komagataella pastoris 49.47 0.00e+00 959.00
IUUC-Lch-050371 Latimeria chalumnae 62.90 0.00e+00 1306.00
IUUC-Lpe-051299 Leersia perrieri 42.93 0.00e+00 851.00
IUUC-Loc-052936 Lepisosteus oculatus 64.13 0.00e+00 1323.00
IUUC-Lma-053315 Leptosphaeria maculans 51.55 0.00e+00 1060.00
IUUC-Laf-053948 Loxodonta africana 62.31 0.00e+00 1299.00
IUUC-Mcc-055843 Macaca mulatta 63.57 0.00e+00 1348.00
IUUC-Meu-056258 Macropus eugenii 63.37 0.00e+00 1335.00
IUUC-Mor-057269 Magnaporthe oryzae 51.19 0.00e+00 1041.00
IUUC-Mpo-057435 Magnaporthe poae 50.87 0.00e+00 1014.00
IUUC-Mtr-058572 Medicago truncatula 44.49 0.00e+00 841.00
IUUC-Mla-059176 Melampsora laricipopulina 53.89 0.00e+00 1058.00
IUUC-Mga-059721 Meleagris gallopavo 41.97 0.00e+00 707.00
IUUC-Mvi-060437 Microbotryum violaceum 50.14 0.00e+00 1008.00
IUUC-Mmr-061405 Microcebus murinus 62.11 0.00e+00 1297.00
IUUC-Mdo-062032 Monodelphis domestica 61.77 0.00e+00 1293.00
IUUC-Mmu-063280 Mus musculus 63.28 0.00e+00 1330.00
IUUC-Mac-065505 Musa acuminata 43.85 0.00e+00 855.00
IUUC-Mpu-066409 Mustela putorius furo 63.76 0.00e+00 1350.00
IUUC-Mlu-067217 Myotis lucifugus 63.28 0.00e+00 1325.00
IUUC-Nfi-068407 Neosartorya fischeri 53.62 0.00e+00 1037.00
IUUC-Ncr-068698 Neurospora crassa 53.95 0.00e+00 1075.00
IUUC-Nle-070072 Nomascus leucogenys 59.85 0.00e+00 1233.00
IUUC-Opr-070715 Ochotona princeps 38.85 0.00e+00 655.00
IUUC-Ont-071671 Oreochromis niloticus 63.61 0.00e+00 1299.00
IUUC-Oan-073268 Ornithorhynchus anatinus 40.81 0.00e+00 663.00
IUUC-Ocu-074544 Oryctolagus cuniculus 63.57 0.00e+00 1348.00
IUUC-Oba-075120 Oryza barthii 42.65 0.00e+00 838.00
IUUC-Obr-076557 Oryza brachyantha 43.04 0.00e+00 825.00
IUUC-Ogl-077887 Oryza glaberrima 42.65 0.00e+00 838.00
IUUC-Ogu-078305 Oryza glumaepatula 42.83 0.00e+00 845.00
IUUC-Oin-080154 Oryza indica 42.73 0.00e+00 844.00
IUUC-Olo-081089 Oryza longistaminata 42.83 0.00e+00 847.00
IUUC-Ome-081942 Oryza meridionalis 42.55 0.00e+00 837.00
IUUC-Oni-082365 Oryza nivara 42.65 0.00e+00 840.00
IUUC-Opu-083977 Oryza punctata 42.94 0.00e+00 844.00
IUUC-Oru-084469 Oryza rufipogon 42.83 0.00e+00 847.00
IUUC-Osa-085949 Oryza sativa 42.75 0.00e+00 847.00
IUUC-Ola-087002 Oryzias latipes 63.61 0.00e+00 1304.00
IUUC-Olu-087687 Ostreococcus lucimarinus 41.48 0.00e+00 739.00
IUUC-Oga-088594 Otolemur garnettii 63.08 0.00e+00 1323.00
IUUC-Oar-090068 Ovis aries 63.28 0.00e+00 1343.00
IUUC-Ptr-090609 Pan troglodytes 40.90 0.00e+00 728.00
IUUC-Pan-092114 Papio anubis 63.47 0.00e+00 1347.00
IUUC-Psi-093489 Pelodiscus sinensis 40.29 0.00e+00 724.00
IUUC-Pma-094214 Petromyzon marinus 52.63 1.00e-43 167.00
IUUC-Pno-095154 Phaeosphaeria nodorum 51.01 0.00e+00 1050.00
IUUC-Ppa-095227 Physcomitrella patens 44.36 0.00e+00 845.00
IUUC-Pfo-097184 Poecilia formosa 63.31 0.00e+00 1298.00
IUUC-Pab-097861 Pongo abelii 62.89 0.00e+00 1308.00
IUUC-Pop-098934 Populus trichocarpa 44.53 0.00e+00 894.00
IUUC-Pca-100347 Procavia capensis 60.35 0.00e+00 1095.00
IUUC-Ppe-102012 Prunus persica 43.90 0.00e+00 873.00
IUUC-Pva-102584 Pteropus vampyrus 63.47 0.00e+00 1370.00
IUUC-Pgr-103336 Puccinia graminis 52.16 0.00e+00 1003.00
IUUC-Ptt-103939 Puccinia triticina 52.76 0.00e+00 1009.00
IUUC-Pte-104200 Pyrenophora teres 52.13 0.00e+00 1063.00
IUUC-Pyt-104441 Pyrenophora triticirepentis 51.15 0.00e+00 1052.00
IUUC-Rno-105462 Rattus norvegicus 62.98 0.00e+00 1323.00
IUUC-Sce-106245 Saccharomyces cerevisiae 48.88 0.00e+00 1004.00
IUUC-Sha-107142 Sarcophilus harrisii 63.18 0.00e+00 1340.00
IUUC-Sja-107841 Schizosaccharomyces japonicus 52.73 0.00e+00 1073.00
IUUC-Spo-108034 Schizosaccharomyces pombe 53.41 0.00e+00 1069.00
IUUC-Ssl-108497 Sclerotinia sclerotiorum 52.32 0.00e+00 1013.00
IUUC-Smo-108912 Selaginella moellendorffii 44.92 0.00e+00 872.00
IUUC-Sit-110281 Setaria italica 43.33 0.00e+00 858.00
IUUC-Sly-110914 Solanum lycopersicum 44.81 0.00e+00 893.00
IUUC-Stu-112109 Solanum tuberosum 44.62 0.00e+00 895.00
IUUC-Sar-113737 Sorex araneus 63.37 0.00e+00 1336.00
IUUC-Sbi-114089 Sorghum bicolor 43.23 0.00e+00 857.00
IUUC-Sre-115148 Sporisorium reilianum 52.56 0.00e+00 1032.00
IUUC-Ssc-115777 Sus scrofa 63.47 0.00e+00 1342.00
IUUC-Tgu-116565 Taeniopygia guttata 40.27 0.00e+00 721.00
IUUC-Tru-118742 Takifugu rubripes 62.73 0.00e+00 1251.00
IUUC-Tsy-119436 Tarsius syrichta 36.43 6.00e-176 610.00
IUUC-Tni-120401 Tetraodon nigroviridis 63.38 0.00e+00 1259.00
IUUC-Tca-121672 Theobroma cacao 44.42 0.00e+00 869.00
IUUC-Tre-122009 Trichoderma reesei 52.18 0.00e+00 1001.00
IUUC-Tvi-122259 Trichoderma virens 51.79 0.00e+00 984.00
IUUC-Tae-125113 Triticum aestivum 44.09 0.00e+00 825.00
IUUC-Tur-126330 Triticum urartu 43.52 0.00e+00 850.00
IUUC-Tme-127055 Tuber melanosporum 50.48 0.00e+00 946.00
IUUC-Tbe-127487 Tupaia belangeri 60.08 8.00e-175 606.00
IUUC-Ttr-128331 Tursiops truncatus 63.08 0.00e+00 1322.00
IUUC-Uma-129387 Ustilago maydis 52.94 0.00e+00 1033.00
IUUC-Vda-129977 Verticillium dahliae 51.54 0.00e+00 970.00
IUUC-Vpa-130716 Vicugna pacos 39.54 0.00e+00 696.00
IUUC-Vvi-130857 Vitis vinifera 44.66 0.00e+00 881.00
IUUC-Xtr-132026 Xenopus tropicalis 51.74 0.00e+00 962.00
IUUC-Xma-133805 Xiphophorus maculatus 63.31 0.00e+00 1280.00
IUUC-Yli-134547 Yarrowia lipolytica 49.90 0.00e+00 1036.00
IUUC-Zma-135052 Zea mays 43.46 0.00e+00 860.00
Created Date 25-Jun-2017

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