iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-06	29.3	1512	1543

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           H + vt l   ++ +llvs+s D+t+++WDlr+
   Q: 1512 HDGYVTKL-VaPEsHLLVSSSLDKTLRIWDLRK 1543
           77778886.3456699**************986 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

May act predominantly to suppress BCHC1, which itself is a negative factor in protein storage vacuole (PSV) trafficking regulation and plant effector triggered immunity (ETI). Required for ETI, but not for cell death.

Protein Sequence
(Fasta)

MRGEDSDLCF DCLDQRINSD FSDQIVFSYG VSDSPLPFGS SAVVKVSDSS EEFSASCSSC 60
ESTSSQFILE YLRKDEHGCL AKYVDKFVVK DREGNSNDAV ESDECLDCST SGSQATEDDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAATAAAG CAACAATAAT AGTTATAGGC TAAAACGGCG TCGTTGAGGA GAAAACACGG 60
CGTTTCTTGG CCGTGCTTTT TGTTTTTCAG GTCGTCGAGA TTGATCGGAT CCGGATCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0853--WD repeat

Interpro

IPR000409--BEACH_dom
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008266--Tyr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50197--BEACH
PS00109--PROTEIN_KINASE_TYR
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF02138--Beach
PF00069--Pkinase

SMART

SM01026--Beach
SM00220--S_TKc
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0009816--P:defense response to bacterium, incompatible interaction
GO:0006623--P:protein targeting to vacuole

KEGG

ath:AT5G18525

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001149	Aegilops tauschii	46.45	0.00e+00	1315.00
IUUC-Aml-001469	Ailuropoda melanoleuca	40.00	2.00e-65	244.00
IUUC-Atr-003087	Amborella trichopoda	50.45	0.00e+00	1513.00
IUUC-Aly-006198	Arabidopsis lyrata	94.31	2.00e-159	554.00
IUUC-Ame-011832	Astyanax mexicanus	42.24	5.00e-75	276.00
IUUC-Bdi-014656	Brachypodium distachyon	48.96	0.00e+00	1415.00
IUUC-Bol-016288	Brassica oleracea	86.10	0.00e+00	2782.00
IUUC-Bra-017480	Brassica rapa	83.39	0.00e+00	2625.00
IUUC-Cel-018315	Caenorhabditis elegans	45.30	3.00e-52	200.00
IUUC-Cfa-020689	Canis familiaris	41.19	7.00e-72	266.00
IUUC-Csa-023209	Chlorocebus sabaeus	40.67	3.00e-69	257.00
IUUC-Csv-025966	Ciona savignyi	38.50	1.00e-65	245.00
IUUC-Dre-027665	Danio rerio	41.46	9.00e-75	275.00
IUUC-Dno-029751	Dasypus novemcinctus	40.00	1.00e-69	258.00
IUUC-Dme-032002	Drosophila melanogaster	37.81	1.00e-68	255.00
IUUC-Fca-036329	Felis catus	39.90	4.00e-69	257.00
IUUC-Fal-037479	Ficedula albicollis	39.79	2.00e-72	267.00
IUUC-Gga-040649	Gallus gallus	40.67	9.00e-74	272.00
IUUC-Gma-043542	Glycine max	55.97	0.00e+00	1806.00
IUUC-Ggo-044633	Gorilla gorilla	39.04	4.00e-68	253.00
IUUC-Hsa-045906	Homo sapiens	40.62	4.00e-68	253.00
IUUC-Hvu-047635	Hordeum vulgare	50.30	0.00e+00	1385.00
IUUC-Itr-048923	Ictidomys tridecemlineatus	42.09	4.00e-72	266.00
IUUC-Lch-049479	Latimeria chalumnae	43.65	2.00e-75	278.00
IUUC-Lpe-051541	Leersia perrieri	45.34	0.00e+00	1275.00
IUUC-Loc-051885	Lepisosteus oculatus	39.38	1.00e-73	272.00
IUUC-Laf-053778	Loxodonta africana	40.78	3.00e-71	264.00
IUUC-Mtr-058486	Medicago truncatula	56.24	0.00e+00	1781.00
IUUC-Mmr-061010	Microcebus murinus	41.10	1.00e-69	258.00
IUUC-Mdo-062572	Monodelphis domestica	40.20	2.00e-70	261.00
IUUC-Mmu-063810	Mus musculus	40.56	2.00e-71	265.00
IUUC-Mac-065431	Musa acuminata	50.81	0.00e+00	741.00
IUUC-Nle-069919	Nomascus leucogenys	52.03	5.00e-66	246.00
IUUC-Ocu-074626	Oryctolagus cuniculus	40.62	2.00e-71	264.00
IUUC-Oba-075734	Oryza barthii	47.28	0.00e+00	1394.00
IUUC-Obr-076493	Oryza brachyantha	51.84	0.00e+00	1425.00
IUUC-Ogl-077248	Oryza glaberrima	48.55	0.00e+00	1461.00
IUUC-Ogu-077961	Oryza glumaepatula	49.18	0.00e+00	1369.00
IUUC-Oin-079930	Oryza indica	45.98	0.00e+00	741.00
IUUC-Olo-080512	Oryza longistaminata	44.16	0.00e+00	686.00
IUUC-Ome-081701	Oryza meridionalis	46.32	0.00e+00	1348.00
IUUC-Oni-082138	Oryza nivara	45.98	0.00e+00	742.00
IUUC-Opu-083350	Oryza punctata	47.82	0.00e+00	1420.00
IUUC-Oru-085133	Oryza rufipogon	47.33	0.00e+00	1382.00
IUUC-Osa-086042	Oryza sativa	48.28	0.00e+00	1450.00
IUUC-Oar-089796	Ovis aries	40.73	7.00e-72	266.00
IUUC-Ptr-091248	Pan troglodytes	39.79	2.00e-67	251.00
IUUC-Pan-091811	Papio anubis	39.79	1.00e-67	251.00
IUUC-Pfo-096830	Poecilia formosa	41.42	3.00e-77	284.00
IUUC-Pop-100019	Populus trichocarpa	59.52	0.00e+00	1880.00
IUUC-Ppe-101526	Prunus persica	58.93	0.00e+00	1862.00
IUUC-Rno-105590	Rattus norvegicus	41.06	8.00e-71	262.00
IUUC-Smo-108909	Selaginella moellendorffii	37.59	4.00e-96	344.00
IUUC-Sit-109791	Setaria italica	52.34	0.00e+00	689.00
IUUC-Sly-111032	Solanum lycopersicum	56.35	0.00e+00	1556.00
IUUC-Sbi-114810	Sorghum bicolor	45.21	0.00e+00	709.00
IUUC-Tca-121706	Theobroma cacao	60.22	0.00e+00	1870.00
IUUC-Tae-125333	Triticum aestivum	48.37	0.00e+00	1458.00
IUUC-Tur-126547	Triticum urartu	44.63	0.00e+00	1216.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence