iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtl.tghsa 97
           e+vldap ++ddfylnLldW+s+nvla+aLg +vylw+a++g+  kl  + ee+  vts++w+++g  la+G +++ev+++D+ ++++vrtl  gh +
   Q: 120  ERVLDAPGIADDFYLNLLDWGSSNVLAIALGDTVYLWDASSGSTYKLVTIdEEEGPVTSINWTQDGLDLAIGLDNSEVQLWDCVSNRQVRTLrGGHES 217
           79************************************************778889************************************889*** PP
   S: 98   rvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse.......Plkkfkehkaavkaiaws 188
           rvg+L+Wn+++l++G+ dg+i+ +dvr++   ++t+ +h++evCGlkw+e++k+LasGGnDn+v++wd++s          l++f+eh+aav+a+aw+
   Q: 218  RVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIVETYLGHTEEVCGLKWSESGKKLASGGNDNVVHIWDHRSVAssnptrqWLHRFEEHTAAVRALAWC 315
           *********************************************************************9876667444457899************* PP
   S: 189  PwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivtaa 286
           P+q slLa+GGG  D +ikfwnt tga+l++++tgsqvcsllwsk+++el+s+hGf++n++tlwkyps+ k+ael+gh++Rvl +a spdg ++++aa
   Q: 316  PFQASLLATGGGVGDGKIKFWNTHTGACLNSVETGSQVCSLLWSKSERELLSSHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAA 413
           ************************************************************************************************** PP
   S: 287  gDetlrfwklfdkkk 301
           gDetlr+w++f + +
   Q: 414  GDETLRLWNVFGEPP 428
           ***********8765 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gHt++v++l++  s++ l+sG++D+++++WD
   Q: 255  GHTEEVCGLKWseSGKKLASGGNDNVVHIWD 285
           8**********877799************** PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

Protein Sequence
(Fasta)

MMNTSSHLKA QASCPLVEHF LRRKLSKENF DRFIPNRSAM DFDFANYALT QGRKRNVDEV 60
TSASRKAYMT QLAEAMNQNR TRILAFRNKP KALLSSNHSD PPHQQPISVK PRRYIPQNSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTATGATGAA CACTTCTTCA CATTTAAAGG CACAAGCTTC GTGTCCACTT GTAGAACACT 60
TTCTCCGTCG GAAACTTTCC AAGGAAAACT TCGACAGATT CATACCGAAT AGATCGGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0498--Mitosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0019900--F:kinase binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0016567--P:protein ubiquitination

KEGG

ath:AT5G27570

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence