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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Ath-006675
UUCD1 version UUC-ArT-01508
Ensembl Protein ID AT5G44280.2
UniProt Accession Q9FKW0; RNG1A_ARATH
Genbank Protein ID BAB10113.1; AED95085.1; AT5G44280.1
Protein Name Putative E3 ubiquitin-protein ligase RING1a; Polycomb complex protein RING1a; Protein RING1a; RING-type E3 ubiquitin transferase RING1a; Ring finger protein 434
Genbank Nucleotide ID AB011475; CP002688; AK228896
Gene Name RING1A; RF434; At5g44280; K9L2.3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT5G44280 AT5G44280.1 AT5G44280.1
AT5G44280 AT5G44280.2 AT5G44280.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
HINTMentha
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 20933424
ULD/UDP/UFD/RAWUL RAWUL 24465219
Classification
Family E-value Score Start End
ULD/UDP/UFD/RAWUL 3.40e-21 76.4 412 520
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsklkkkylrcsarltVkhlkkflaeklklsssyevdllce............dev................LednetLeeik 70
    i+++L++l++++++d l+++yl+c+++l Vk+l++f+a++++l+++ ev+ll++ + LednetL+++k
   Q: 412 IHVKLVSLDTKCIPD---LPQPYLCCRPTLLVKQLREFVALQIHLKTE-EVELLVTrrrvgedaaienL-PavtpasaaaskdemlsLEDNETLSRLK 504
    89*************...******************************.*******9888888777750.15555555566666689*********** PP
   S: 71 yifiwkkegpLvLqYr 86
    ++fi+++e++L+++Yr
   Q: 505 IDFISSHEQHLIIAYR 520
    ***************9 PP
   

Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description



     As part of the PRC1-like complex, repress class I KNOX gene expression. PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.
As part of the PRC1-like complex, repress class I KNOX gene expression. PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.
Protein Sequence
(Fasta)
MSVKNNSFSS AEIPDVADQP RDRFNPEATQ DLQEKDETKE EKEGDEEVKH DEAEEDQEVV 60
KPNDAEEDDD GDDAEEDEEE EVEAEEDEEA EEEEEEEEEE EEEEEDSKER SPSSISGDQS 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Ath-006675|E3,RING;ULD,RAWUL|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATATCGGCAC CGAACCAAAA ACACAAACGA AGCAGAACAA GAAGAAGAAG AAGAATAGAG 60
AGAGACGTAG AGAGAGAGAG ACAAAGGCTG AGCCTTTTGG GTTTCTCTTA GAGAGAAGAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ath-006675|E3,RING;ULD,RAWUL|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0035102--C:PRC1 complex
GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0001709--P:cell fate determination
GO:0016569--P:covalent chromatin modification
GO:0010076--P:maintenance of floral meristem identity
GO:0010077--P:maintenance of inflorescence meristem identity
GO:0010492--P:maintenance of shoot apical meristem identity
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0016567--P:protein ubiquitination
GO:0006351--P:transcription, DNA-templated

KEGG ath:AT5G44280
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aly-005911 Arabidopsis lyrata 88.46 4.00e-169 587.00
IUUC-Bol-015993 Brassica oleracea 70.21 2.00e-111 395.00
IUUC-Bra-017150 Brassica rapa 78.77 4.00e-62 231.00
Created Date 25-Jun-2017

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