iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	9.50e-09	36.2	78	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 4    ClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           C +C+ gg+    l++C+ C + +H aCl+++  +  pn + wiCpkC+
   Q: 78   CVICDLGGD----LLCCDSCPRTYHTACLNPP-LKRIPNGK-WICPKCS 120
           *********....*******************.*******7.******7 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3 (By similarity). Probable chromatin remodeling factor.

Protein Sequence
(Fasta)

MKDSGSEMIK RDWVMKQKRR KLPSILDILD QKVDSSMAFD SPEYTSSSKP SKQRLKTDST 60
PERNSSKRKG NDGNYFECVI CDLGGDLLCC DSCPRTYHTA CLNPPLKRIP NGKWICPKCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTCTGTCT AGTAGTATCT AAACGAATTT AACTAAAACC AGCTAAAAAC AAGAAGCATA 60
AAAATAATAT CAAAGTAGAA ACTAAAGGAT CTAATAAGTA AGACAAAATT CGAAATTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000953--Chromo/chromo_shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR009463--DUF1087
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR009057--Homeobox-like
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50013--CHROMO_2
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00385--Chromo
PF06465--DUF1087
PF00271--Helicase_C
PF00628--PHD
PF00176--SNF2_N

SMART

SM00298--CHROMO
SM00487--DEXDc
SM01147--DUF1087
SM00490--HELICc
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0004386--F:helicase activity
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification

KEGG

ath:AT5G44800

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001701	Ailuropoda melanoleuca	39.11	2.00e-140	494.00
IUUC-Apl-003406	Anas platyrhynchos	39.68	7.00e-139	488.00
IUUC-Aca-004560	Anolis carolinensis	40.16	1.00e-143	504.00
IUUC-Aly-005645	Arabidopsis lyrata	90.77	0.00e+00	3654.00
IUUC-Ame-011352	Astyanax mexicanus	40.81	1.00e-147	518.00
IUUC-Bta-012868	Bos taurus	40.40	3.00e-143	503.00
IUUC-Bol-016073	Brassica oleracea	78.29	0.00e+00	3185.00
IUUC-Bra-016724	Brassica rapa	79.38	0.00e+00	3201.00
IUUC-Cel-018108	Caenorhabditis elegans	40.53	1.00e-140	494.00
IUUC-Cja-019018	Callithrix jacchus	40.28	2.00e-143	503.00
IUUC-Cfa-021055	Canis familiaris	40.40	7.00e-143	501.00
IUUC-Cpo-021523	Cavia porcellus	40.28	1.00e-142	501.00
IUUC-Csa-023084	Chlorocebus sabaeus	39.77	4.00e-143	503.00
IUUC-Cho-024361	Choloepus hoffmanni	40.51	6.00e-120	425.00
IUUC-Csv-025847	Ciona savignyi	37.56	2.00e-134	473.00
IUUC-Dre-028043	Danio rerio	40.72	5.00e-145	509.00
IUUC-Dno-029656	Dasypus novemcinctus	39.30	4.00e-143	502.00
IUUC-Dor-030167	Dipodomys ordii	40.07	9.00e-142	498.00
IUUC-Dme-032150	Drosophila melanogaster	36.67	2.00e-135	476.00
IUUC-Ete-032757	Echinops telfairi	38.82	1.00e-120	428.00
IUUC-Eca-034372	Equus caballus	39.11	3.00e-141	496.00
IUUC-Eeu-034634	Erinaceus europaeus	42.88	1.00e-91	332.00
IUUC-Fca-036043	Felis catus	40.28	1.00e-142	501.00
IUUC-Fal-037282	Ficedula albicollis	39.24	1.00e-139	491.00
IUUC-Gmo-038957	Gadus morhua	42.48	1.00e-140	494.00
IUUC-Gga-040607	Gallus gallus	39.52	1.00e-142	501.00
IUUC-Gac-041375	Gasterosteus aculeatus	39.93	2.00e-149	523.00
IUUC-Gma-043999	Glycine max	45.39	1.00e-160	560.00
IUUC-Ggo-044514	Gorilla gorilla	39.89	2.00e-143	504.00
IUUC-Hsa-046181	Homo sapiens	39.66	2.00e-143	503.00
IUUC-Itr-048463	Ictidomys tridecemlineatus	40.28	3.00e-142	499.00
IUUC-Lch-050343	Latimeria chalumnae	38.70	1.00e-147	517.00
IUUC-Loc-052383	Lepisosteus oculatus	39.11	6.00e-134	472.00
IUUC-Laf-053870	Loxodonta africana	40.40	8.00e-143	501.00
IUUC-Mcc-055856	Macaca mulatta	39.89	2.00e-143	503.00
IUUC-Meu-056292	Macropus eugenii	33.61	5.00e-48	186.00
IUUC-Mga-059630	Meleagris gallopavo	39.59	4.00e-143	502.00
IUUC-Mmr-060986	Microcebus murinus	39.56	7.00e-142	498.00
IUUC-Mdo-062971	Monodelphis domestica	40.16	2.00e-140	493.00
IUUC-Mmu-063644	Mus musculus	39.95	6.00e-143	502.00
IUUC-Mpu-066528	Mustela putorius furo	39.22	4.00e-141	496.00
IUUC-Mlu-067355	Myotis lucifugus	40.28	7.00e-143	501.00
IUUC-Nle-069824	Nomascus leucogenys	40.00	1.00e-144	507.00
IUUC-Opr-070960	Ochotona princeps	39.28	4.00e-135	476.00
IUUC-Ont-072418	Oreochromis niloticus	39.53	7.00e-142	498.00
IUUC-Oan-072885	Ornithorhynchus anatinus	40.03	2.00e-104	374.00
IUUC-Ocu-074438	Oryctolagus cuniculus	40.28	2.00e-142	500.00
IUUC-Ola-086880	Oryzias latipes	39.82	5.00e-143	502.00
IUUC-Oga-088775	Otolemur garnettii	39.45	1.00e-141	498.00
IUUC-Oar-089784	Ovis aries	40.40	6.00e-143	502.00
IUUC-Ptr-090586	Pan troglodytes	39.54	2.00e-142	500.00
IUUC-Pan-092282	Papio anubis	39.89	1.00e-143	504.00
IUUC-Psi-093007	Pelodiscus sinensis	39.41	6.00e-142	498.00
IUUC-Ppa-095491	Physcomitrella patens	60.50	0.00e+00	952.00
IUUC-Pfo-096265	Poecilia formosa	40.51	5.00e-151	529.00
IUUC-Pab-097677	Pongo abelii	39.66	6.00e-143	502.00
IUUC-Pca-100829	Procavia capensis	42.50	2.00e-138	486.00
IUUC-Pva-103186	Pteropus vampyrus	39.30	8.00e-142	498.00
IUUC-Rno-105378	Rattus norvegicus	39.15	3.00e-141	496.00
IUUC-Sha-107233	Sarcophilus harrisii	40.16	5.00e-140	492.00
IUUC-Smo-108946	Selaginella moellendorffii	61.38	0.00e+00	1024.00
IUUC-Sly-110976	Solanum lycopersicum	41.33	2.00e-158	553.00
IUUC-Ssc-116303	Sus scrofa	39.38	1.00e-141	497.00
IUUC-Tgu-116779	Taeniopygia guttata	39.35	2.00e-138	487.00
IUUC-Tru-118648	Takifugu rubripes	41.20	9.00e-153	535.00
IUUC-Tsy-119261	Tarsius syrichta	41.63	7.00e-120	425.00
IUUC-Tni-120039	Tetraodon nigroviridis	40.62	4.00e-146	512.00
IUUC-Tbe-128117	Tupaia belangeri	40.11	3.00e-81	296.00
IUUC-Ttr-128301	Tursiops truncatus	38.70	5.00e-137	482.00
IUUC-Vpa-130209	Vicugna pacos	43.35	3.00e-69	257.00
IUUC-Vvi-130849	Vitis vinifera	41.72	2.00e-158	553.00
IUUC-Xtr-132668	Xenopus tropicalis	42.94	6.00e-133	468.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence