iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093367

Ensembl Protein ID

ENSPSIP00000002177.1

UniProt Accession

K7F2B7; K7F2B7_PELSI

Genbank Protein ID

ENSPSIP00000002177

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01139300

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000002171.1	ENSPSIT00000002184.1	ENSPSIP00000002177.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-32	109.1	406	445
UBD/Beta-Prp	1.80e-63	214.5	317	605

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 406  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 445
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           ++++h++ +++v+fsp+++llatg++d+++k+w+v+   +    slsg +a++t+++f+++g++l+ +s+D + ++w ++++   htl+
   Q: 317  VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDRCelKGSLSGSNAGITSIEFDSSGSYLLAASNDFASRIWTVDDSRLRHTLT 405
           5799********************************99998899********************************************* PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd++t++++++l+    
   Q: 406  GHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRTESIVQELE--LF 488
           ***************************************9999988....888888889*************************6..69 PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhns 265
           ++++ l+++++++el+++s+d  +k+ dl+ +++ +t+ ++     +  ++v fsp++++++ gs+Dg ++iW++ +g++ +tl++h+s
   Q: 489  GRITALDLNPERTELLTCSRDDLLKIIDLRVNTVKQTFSAQGfkcgSDWTRVVFSPDGNYVAAGSADGALYIWNVLTGKVERTLAKHHS 577
           ******************************99998888888777776667799************************************ PP
   S: 266  svisvavlsfgdnvlvlgsedskvniwk 293
           s i   ++s+ + ++v++++ +k+ +w+
   Q: 578  SPINAVTWSPAGAHVVSVDKGNKAVLWS 605
           ********************99999996 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MTSGLRAASF PTWKRHIAEE LRRRDRLQRQ AFEEIILQYN KLLEKTDLHA VLADKINAEK 60
YDLQSRHEIS PGHDGTRNEA QLQEMAQMRI KHQEELTELH KKRGELAQSV IDLNNQMQQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNCTCCCCC 60
CCGCCCCCCC GCCAGGAGCC TCCCCCCCCG CTCTCCCCAG GCTGTGCCCC CTCCGCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0039689--P:negative stranded viral RNA replication

KEGG

pss:102462041

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	28.52	9.00e-35	141.00
IUUC-Aml-002242	Ailuropoda melanoleuca	79.58	0.00e+00	970.00
IUUC-Atr-003073	Amborella trichopoda	24.62	2.00e-32	132.00
IUUC-Apl-003384	Anas platyrhynchos	93.07	0.00e+00	1112.00
IUUC-Aca-004962	Anolis carolinensis	87.80	0.00e+00	1072.00
IUUC-Aly-005435	Arabidopsis lyrata	34.98	7.00e-49	187.00
IUUC-Ath-006948	Arabidopsis thaliana	34.98	7.00e-49	187.00
IUUC-Ame-010915	Astyanax mexicanus	80.06	2.00e-156	544.00
IUUC-Bta-012388	Bos taurus	85.71	0.00e+00	1079.00
IUUC-Bdi-014231	Brachypodium distachyon	24.73	6.00e-40	158.00
IUUC-Bol-016174	Brassica oleracea	35.97	3.00e-50	192.00
IUUC-Bra-017165	Brassica rapa	35.31	2.00e-49	190.00
IUUC-Cel-018131	Caenorhabditis elegans	30.18	7.00e-67	248.00
IUUC-Cja-018898	Callithrix jacchus	77.35	0.00e+00	907.00
IUUC-Cfa-020484	Canis familiaris	87.97	0.00e+00	1077.00
IUUC-Cpo-022156	Cavia porcellus	86.28	0.00e+00	1042.00
IUUC-Csa-024019	Chlorocebus sabaeus	84.18	0.00e+00	1016.00
IUUC-Cho-024311	Choloepus hoffmanni	73.72	0.00e+00	893.00
IUUC-Cin-025260	Ciona intestinalis	37.48	2.00e-101	362.00
IUUC-Csv-025836	Ciona savignyi	45.67	3.00e-51	194.00
IUUC-Dre-027702	Danio rerio	73.86	0.00e+00	902.00
IUUC-Dno-029728	Dasypus novemcinctus	83.17	0.00e+00	1066.00
IUUC-Dme-031595	Drosophila melanogaster	39.52	2.00e-112	399.00
IUUC-Ete-032969	Echinops telfairi	72.31	0.00e+00	741.00
IUUC-Eca-034214	Equus caballus	89.84	0.00e+00	904.00
IUUC-Eeu-034537	Erinaceus europaeus	82.98	0.00e+00	857.00
IUUC-Fca-036005	Felis catus	84.43	0.00e+00	999.00
IUUC-Fal-037593	Ficedula albicollis	91.28	0.00e+00	1053.00
IUUC-Gmo-039042	Gadus morhua	67.22	0.00e+00	707.00
IUUC-Gga-040986	Gallus gallus	90.37	0.00e+00	1123.00
IUUC-Gac-041351	Gasterosteus aculeatus	75.37	0.00e+00	941.00
IUUC-Gma-043265	Glycine max	28.82	9.00e-56	211.00
IUUC-Ggo-045427	Gorilla gorilla	84.29	0.00e+00	1039.00
IUUC-Hsa-046632	Homo sapiens	86.66	0.00e+00	1062.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	82.73	0.00e+00	999.00
IUUC-Lch-049439	Latimeria chalumnae	51.07	2.00e-148	519.00
IUUC-Lpe-051254	Leersia perrieri	25.76	1.00e-43	170.00
IUUC-Loc-052610	Lepisosteus oculatus	76.37	0.00e+00	935.00
IUUC-Laf-053936	Loxodonta africana	82.46	0.00e+00	1029.00
IUUC-Mcc-055504	Macaca mulatta	81.82	0.00e+00	1051.00
IUUC-Meu-056516	Macropus eugenii	81.25	0.00e+00	991.00
IUUC-Mtr-058062	Medicago truncatula	32.67	1.00e-45	177.00
IUUC-Mga-059777	Meleagris gallopavo	90.17	0.00e+00	1103.00
IUUC-Mmr-061298	Microcebus murinus	85.71	0.00e+00	1053.00
IUUC-Mdo-062969	Monodelphis domestica	85.74	0.00e+00	1075.00
IUUC-Mmu-064076	Mus musculus	83.44	0.00e+00	1025.00
IUUC-Mac-065161	Musa acuminata	26.46	5.00e-46	178.00
IUUC-Mpu-066196	Mustela putorius furo	85.39	0.00e+00	1050.00
IUUC-Mlu-067651	Myotis lucifugus	86.02	0.00e+00	1055.00
IUUC-Nle-069853	Nomascus leucogenys	85.50	0.00e+00	1044.00
IUUC-Opr-070350	Ochotona princeps	86.83	3.00e-111	395.00
IUUC-Ont-072489	Oreochromis niloticus	75.25	0.00e+00	921.00
IUUC-Oan-072703	Ornithorhynchus anatinus	81.31	0.00e+00	987.00
IUUC-Ocu-074205	Oryctolagus cuniculus	82.83	0.00e+00	1039.00
IUUC-Oba-075619	Oryza barthii	25.20	4.00e-41	162.00
IUUC-Obr-076632	Oryza brachyantha	29.97	1.00e-39	157.00
IUUC-Ogl-077671	Oryza glaberrima	25.20	3.00e-41	162.00
IUUC-Ogu-078052	Oryza glumaepatula	25.39	2.00e-41	162.00
IUUC-Oin-079611	Oryza indica	25.20	5.00e-40	158.00
IUUC-Olo-080408	Oryza longistaminata	25.39	3.00e-38	152.00
IUUC-Ome-081560	Oryza meridionalis	25.39	2.00e-41	163.00
IUUC-Oni-082145	Oryza nivara	25.20	4.00e-41	162.00
IUUC-Opu-083918	Oryza punctata	25.20	7.00e-38	151.00
IUUC-Oru-084858	Oryza rufipogon	25.20	9.00e-40	157.00
IUUC-Osa-086277	Oryza sativa	25.20	6.00e-40	158.00
IUUC-Ola-086816	Oryzias latipes	72.36	3.00e-105	374.00
IUUC-Olu-087622	Ostreococcus lucimarinus	35.22	2.00e-45	176.00
IUUC-Oga-088765	Otolemur garnettii	83.55	0.00e+00	972.00
IUUC-Oar-090196	Ovis aries	83.01	0.00e+00	942.00
IUUC-Ptr-091676	Pan troglodytes	86.66	0.00e+00	1062.00
IUUC-Pan-092068	Papio anubis	85.10	0.00e+00	1045.00
IUUC-Ppa-095699	Physcomitrella patens	29.15	5.00e-44	171.00
IUUC-Pfo-096067	Poecilia formosa	74.08	0.00e+00	891.00
IUUC-Pab-098111	Pongo abelii	84.29	0.00e+00	1039.00
IUUC-Pop-099116	Populus trichocarpa	26.83	5.00e-50	192.00
IUUC-Pca-100680	Procavia capensis	75.50	0.00e+00	858.00
IUUC-Ppe-101790	Prunus persica	25.68	4.00e-48	185.00
IUUC-Pva-102871	Pteropus vampyrus	82.42	0.00e+00	974.00
IUUC-Rno-106088	Rattus norvegicus	82.80	0.00e+00	1014.00
IUUC-Sha-106984	Sarcophilus harrisii	88.21	0.00e+00	1065.00
IUUC-Smo-109404	Selaginella moellendorffii	26.96	7.00e-44	171.00
IUUC-Sit-110828	Setaria italica	27.15	8.00e-47	181.00
IUUC-Sly-111009	Solanum lycopersicum	26.60	3.00e-51	195.00
IUUC-Stu-112370	Solanum tuberosum	26.80	1.00e-52	200.00
IUUC-Sar-113659	Sorex araneus	59.80	7.00e-85	306.00
IUUC-Sbi-114819	Sorghum bicolor	26.00	5.00e-45	175.00
IUUC-Ssc-116241	Sus scrofa	86.74	0.00e+00	1048.00
IUUC-Tgu-116576	Taeniopygia guttata	93.25	0.00e+00	1145.00
IUUC-Tru-118336	Takifugu rubripes	66.67	0.00e+00	771.00
IUUC-Tsy-119006	Tarsius syrichta	81.54	0.00e+00	990.00
IUUC-Tni-120300	Tetraodon nigroviridis	76.55	0.00e+00	897.00
IUUC-Tca-121002	Theobroma cacao	28.16	6.00e-56	211.00
IUUC-Tae-123139	Triticum aestivum	28.52	2.00e-35	143.00
IUUC-Tur-126463	Triticum urartu	28.52	5.00e-35	142.00
IUUC-Tbe-127631	Tupaia belangeri	88.24	0.00e+00	863.00
IUUC-Ttr-129005	Tursiops truncatus	78.02	2.00e-153	535.00
IUUC-Vpa-130246	Vicugna pacos	77.31	0.00e+00	782.00
IUUC-Vvi-130878	Vitis vinifera	35.31	3.00e-48	185.00
IUUC-Xtr-132798	Xenopus tropicalis	74.67	0.00e+00	891.00
IUUC-Xma-133264	Xiphophorus maculatus	74.66	0.00e+00	897.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence