iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117427

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01015555

Gene Name

UBE2K

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008793.1	ENSTGUT00000009159.1	ENSTGUP00000009062.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.70e-44	150.8	3	126
UBD/Alpha-Helix/UBA	3.50e-11	42.7	141	179

Active Site

Position(s)	Description	Evidence
72	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 13   ppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsves 100
           ++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+ilk  ++W +a+++++
   Q: 3    SKNQIKVDLVDE-NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDILK--DQWAAAMTLRT 88
           67899*******.9***************************************************99********9..*********** PP
   S: 101  vllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 89   VLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 126
           ***********************************986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+e+l++MGFdr++++ aL + ++++e A+e+Ll+
   Q: 141  EYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLS 179
           6789*********************************97 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

KTSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI KIPETYPFNP PKVRFITKIW 60
HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA EPDDPQDAVV ANQYKQNPEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGACGAGCA AAAATCAAAT TAAAGTAGAT CTTGTAGATG AGAATTTTAC AGAATTAAGA 60
GGAGAAATAG CAGGACCTCC GGACACACCA TATGAAGGCA AGTAAAGTTT TTGTGTATGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0032433--C:filopodium tip
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0035458--P:cellular response to interferon-beta
GO:0010994--P:free ubiquitin chain polymerization
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	66.67	2.00e-25	108.00
IUUC-Aml-001286	Ailuropoda melanoleuca	99.44	6.00e-98	349.00
IUUC-Atr-003063	Amborella trichopoda	51.46	8.00e-38	149.00
IUUC-Apl-004122	Anas platyrhynchos	99.43	7.00e-95	338.00
IUUC-Aca-004565	Anolis carolinensis	100.00	4.00e-98	349.00
IUUC-Aly-006390	Arabidopsis lyrata	51.72	6.00e-42	162.00
IUUC-Ath-006637	Arabidopsis thaliana	50.00	4.00e-39	153.00
IUUC-Ago-007714	Ashbya gossypii	47.47	9.00e-36	142.00
IUUC-Acl-008189	Aspergillus clavatus	55.65	4.00e-26	110.00
IUUC-Afl-008489	Aspergillus flavus	44.57	4.00e-27	114.00
IUUC-Afu-008850	Aspergillus fumigatus	42.93	8.00e-27	113.00
IUUC-Ani-009361	Aspergillus nidulans	57.26	1.00e-24	105.00
IUUC-Ang-009548	Aspergillus niger	56.10	6.00e-25	107.00
IUUC-Aor-010105	Aspergillus oryzae	44.57	4.00e-27	114.00
IUUC-Ate-010389	Aspergillus terreus	43.48	5.00e-27	114.00
IUUC-Ame-011454	Astyanax mexicanus	96.11	2.00e-95	340.00
IUUC-Bgr-012255	Blumeria graminis	54.76	2.00e-31	129.00
IUUC-Bta-012992	Bos taurus	99.44	6.00e-98	349.00
IUUC-Bci-013806	Botrytis cinerea	44.15	3.00e-35	141.00
IUUC-Bdi-015024	Brachypodium distachyon	53.61	2.00e-38	151.00
IUUC-Bol-015985	Brassica oleracea	51.72	3.00e-42	164.00
IUUC-Bra-016805	Brassica rapa	51.72	2.00e-42	164.00
IUUC-Cel-018353	Caenorhabditis elegans	52.54	6.00e-50	189.00
IUUC-Cja-019051	Callithrix jacchus	98.89	4.00e-97	346.00
IUUC-Cfa-020016	Canis familiaris	99.44	6.00e-98	349.00
IUUC-Cpo-022026	Cavia porcellus	99.44	6.00e-98	349.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	50.84	6.00e-40	156.00
IUUC-Csa-023059	Chlorocebus sabaeus	99.44	6.00e-98	349.00
IUUC-Cho-024276	Choloepus hoffmanni	96.60	2.00e-73	266.00
IUUC-Cin-025598	Ciona intestinalis	61.93	2.00e-50	191.00
IUUC-Csv-025831	Ciona savignyi	63.07	8.00e-50	189.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	51.52	7.00e-33	133.00
IUUC-Cne-027068	Cryptococcus neoformans	43.72	1.00e-38	152.00
IUUC-Dre-028139	Danio rerio	96.11	3.00e-95	340.00
IUUC-Dno-029169	Dasypus novemcinctus	99.44	3.00e-97	346.00
IUUC-Dor-030382	Dipodomys ordii	83.89	2.00e-76	277.00
IUUC-Dse-031335	Dothistroma septosporum	58.87	1.00e-35	142.00
IUUC-Dme-032003	Drosophila melanogaster	68.79	3.00e-61	227.00
IUUC-Ete-032868	Echinops telfairi	89.44	1.00e-76	278.00
IUUC-Eca-033428	Equus caballus	99.44	6.00e-98	349.00
IUUC-Eeu-035103	Erinaceus europaeus	73.44	3.00e-49	186.00
IUUC-Fca-035366	Felis catus	99.44	6.00e-98	349.00
IUUC-Fal-037016	Ficedula albicollis	99.44	6.00e-98	349.00
IUUC-Fox-037969	Fusarium oxysporum	46.84	1.00e-32	132.00
IUUC-Fso-038296	Fusarium solani	46.11	6.00e-34	137.00
IUUC-Gmo-039135	Gadus morhua	95.00	5.00e-94	335.00
IUUC-Ggr-039768	Gaeumannomyces graminis	52.17	7.00e-24	103.00
IUUC-Gga-041018	Gallus gallus	98.89	1.00e-97	348.00
IUUC-Gac-041503	Gasterosteus aculeatus	95.56	7.00e-95	338.00
IUUC-Gma-042779	Glycine max	52.91	4.00e-41	160.00
IUUC-Ggo-045032	Gorilla gorilla	99.44	6.00e-98	349.00
IUUC-Hsa-046490	Homo sapiens	99.44	6.00e-98	349.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	99.44	6.00e-98	349.00
IUUC-Lch-050588	Latimeria chalumnae	68.72	5.00e-76	276.00
IUUC-Lpe-051070	Leersia perrieri	53.01	1.00e-29	122.00
IUUC-Loc-052549	Lepisosteus oculatus	96.67	8.00e-96	342.00
IUUC-Lma-052949	Leptosphaeria maculans	57.72	7.00e-36	143.00
IUUC-Laf-053688	Loxodonta africana	100.00	1.00e-97	347.00
IUUC-Mcc-055606	Macaca mulatta	99.44	6.00e-98	349.00
IUUC-Mor-056946	Magnaporthe oryzae	41.48	4.00e-22	97.40
IUUC-Mpo-057441	Magnaporthe poae	54.48	7.00e-24	103.00
IUUC-Mtr-058002	Medicago truncatula	52.33	3.00e-41	160.00
IUUC-Mla-059007	Melampsora laricipopulina	46.15	1.00e-36	145.00
IUUC-Mga-059254	Meleagris gallopavo	99.44	1.00e-97	347.00
IUUC-Mvi-060346	Microbotryum violaceum	42.54	4.00e-31	127.00
IUUC-Mmr-061211	Microcebus murinus	99.44	6.00e-98	349.00
IUUC-Mdo-062458	Monodelphis domestica	98.33	2.00e-95	340.00
IUUC-Mmu-063648	Mus musculus	99.44	6.00e-98	349.00
IUUC-Mac-065447	Musa acuminata	53.61	5.00e-39	153.00
IUUC-Mpu-066407	Mustela putorius furo	99.44	4.00e-97	347.00
IUUC-Mlu-067682	Myotis lucifugus	100.00	3.00e-98	350.00
IUUC-Nfi-068517	Neosartorya fischeri	42.05	7.00e-27	113.00
IUUC-Ncr-068749	Neurospora crassa	53.97	8.00e-36	143.00
IUUC-Nle-069712	Nomascus leucogenys	99.44	8.00e-98	348.00
IUUC-Opr-070651	Ochotona princeps	99.44	6.00e-98	349.00
IUUC-Ont-071433	Oreochromis niloticus	95.56	9.00e-95	338.00
IUUC-Oan-073058	Ornithorhynchus anatinus	100.00	2.00e-78	283.00
IUUC-Ocu-074939	Oryctolagus cuniculus	99.44	6.00e-98	349.00
IUUC-Oba-075530	Oryza barthii	53.94	1.00e-29	122.00
IUUC-Obr-076838	Oryza brachyantha	53.99	4.00e-29	120.00
IUUC-Ogl-077606	Oryza glaberrima	53.94	1.00e-29	122.00
IUUC-Ogu-078238	Oryza glumaepatula	53.94	1.00e-29	122.00
IUUC-Oin-079643	Oryza indica	53.94	3.00e-29	120.00
IUUC-Ome-081274	Oryza meridionalis	53.94	1.00e-29	122.00
IUUC-Oni-082651	Oryza nivara	53.94	1.00e-29	122.00
IUUC-Opu-083933	Oryza punctata	53.94	2.00e-29	121.00
IUUC-Oru-085054	Oryza rufipogon	53.94	3.00e-29	120.00
IUUC-Osa-085716	Oryza sativa	53.94	3.00e-29	120.00
IUUC-Ola-087043	Oryzias latipes	95.56	7.00e-95	338.00
IUUC-Olu-087846	Ostreococcus lucimarinus	48.86	8.00e-41	159.00
IUUC-Oga-088897	Otolemur garnettii	99.44	1.00e-97	347.00
IUUC-Oar-089673	Ovis aries	99.44	1.00e-97	347.00
IUUC-Ptr-091295	Pan troglodytes	99.44	6.00e-98	349.00
IUUC-Pan-092034	Papio anubis	99.44	1.00e-97	348.00
IUUC-Psi-093498	Pelodiscus sinensis	99.44	6.00e-98	349.00
IUUC-Pma-094115	Petromyzon marinus	86.67	7.00e-85	305.00
IUUC-Pno-095102	Phaeosphaeria nodorum	43.72	6.00e-37	146.00
IUUC-Ppa-095326	Physcomitrella patens	48.85	2.00e-37	147.00
IUUC-Pfo-096940	Poecilia formosa	95.56	9.00e-95	338.00
IUUC-Pab-098279	Pongo abelii	99.44	6.00e-98	349.00
IUUC-Pop-099543	Populus trichocarpa	52.30	3.00e-42	164.00
IUUC-Pca-100782	Procavia capensis	98.89	8.00e-96	342.00
IUUC-Ppe-101789	Prunus persica	52.00	4.00e-36	144.00
IUUC-Pva-102147	Pteropus vampyrus	100.00	3.00e-52	197.00
IUUC-Ptt-103772	Puccinia triticina	48.48	1.00e-34	139.00
IUUC-Pte-104370	Pyrenophora teres	56.91	2.00e-35	142.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	44.26	2.00e-35	141.00
IUUC-Rno-104984	Rattus norvegicus	99.44	6.00e-98	349.00
IUUC-Sce-106394	Saccharomyces cerevisiae	45.09	2.00e-33	134.00
IUUC-Sha-106848	Sarcophilus harrisii	100.00	1.00e-97	348.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	46.28	3.00e-38	151.00
IUUC-Smo-109656	Selaginella moellendorffii	50.87	3.00e-38	150.00
IUUC-Sit-110639	Setaria italica	52.41	3.00e-37	147.00
IUUC-Sly-110978	Solanum lycopersicum	52.30	2.00e-42	164.00
IUUC-Stu-112088	Solanum tuberosum	52.30	7.00e-43	166.00
IUUC-Sar-113285	Sorex araneus	84.36	6.00e-76	275.00
IUUC-Sbi-113986	Sorghum bicolor	52.41	3.00e-37	147.00
IUUC-Ssc-116314	Sus scrofa	99.44	6.00e-98	349.00
IUUC-Tru-118618	Takifugu rubripes	90.56	5.00e-90	322.00
IUUC-Tsy-119208	Tarsius syrichta	99.44	6.00e-98	348.00
IUUC-Tni-119667	Tetraodon nigroviridis	96.11	3.00e-95	340.00
IUUC-Tca-121446	Theobroma cacao	52.87	9.00e-43	165.00
IUUC-Tre-122053	Trichoderma reesei	39.88	6.00e-30	123.00
IUUC-Tae-124726	Triticum aestivum	54.22	7.00e-31	126.00
IUUC-Tme-127024	Tuber melanosporum	51.70	1.00e-37	149.00
IUUC-Tbe-127752	Tupaia belangeri	100.00	2.00e-97	347.00
IUUC-Ttr-128287	Tursiops truncatus	100.00	3.00e-97	346.00
IUUC-Vda-129947	Verticillium dahliae	42.20	9.00e-31	126.00
IUUC-Vpa-130481	Vicugna pacos	99.44	8.00e-98	348.00
IUUC-Vvi-131429	Vitis vinifera	50.29	3.00e-39	153.00
IUUC-Xtr-132710	Xenopus tropicalis	81.32	7.00e-84	302.00
IUUC-Xma-134308	Xiphophorus maculatus	95.00	2.00e-94	337.00
IUUC-Yli-134523	Yarrowia lipolytica	48.30	1.00e-32	132.00
IUUC-Zma-135733	Zea mays	51.12	2.00e-35	141.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence