iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007615

UUCD1 version

UUC-ArT-01475

Ensembl Protein ID

AT5G51450.2

UniProt Accession

Q8W4Q5; Q9FGM8; RIN3_ARATH

Genbank Protein ID

BAB09756.1; AED96082.1; AAL32977.1

Protein Name

E3 ubiquitin protein ligase RIN3; RING-type E3 ubiquitin transferase RIN3; RPM1-interacting protein 3

Genbank Nucleotide ID

AB025621; CP002688; AY062101

Gene Name

RIN3; At5g51450; MFG13.16

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G51450	AT5G51450.2	AT5G51450.2
AT5G51450	AT5G51450.1	AT5G51450.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
PINA	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	16212605; 16531490
UBD/Alpha-Helix/CUE	CUE	16212605

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	1.40e-07	32.8	337	379
UBD/Alpha-Helix/CUE	1.20e-10	42.0	558	595

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+e++ +  + l C+H+fh+ Cl  w  l +  +   +CP+Cr
   Q: 337  CAICREPMAK-AKRLHCNHLFHLGCLRSW--LDQGLNEVYSCPTCR 379
           ********99.888***************..777899999*****8 PP

UBD/Alpha-Helix/CUE

   S: 4    taleqLkeiFPnldysviqvvLeantgsleaavnnLLeg 42
            ++e+++e++P++++++i ++L ++t+s++ +vnnLL++
   Q: 558  AMAETVREVLPHVPDEIIFQDL-QRTNSVSVTVNNLLQM 595
           79********************.**************98 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin protein ligase that acts as positive regulator of RPM1- and RPS2-dependent hypersensitive response (HR), in association with RIN2. Probably not required for RPM1 degradation during HR.

Protein Sequence
(Fasta)

MGITYLHISV ATTALSFVGL QVWTELSLDR LRADGIITKN ISLGNSENTL ELLLSSHTTI 60
ALLASFVLNI YILLVLSLKT LFFGDLYAIE TRKLVERLAN YIIYKGTFLP FVVPRTVFQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATTTAAGT AACTTTTTAT TTACCGCATG GTTTATTATT TTGAGTTTTT TTCTTCCGCA 60
TTTTATATTC TTCATTTTTC CTTGTCCATC GAGAAAGAGA GACAAAAAGA GGACGCAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0381--Hypersensitive response
KW-0472--Membrane
KW-0479--Metal-binding
KW-0611--Plant defense
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0009626--P:plant-type hypersensitive response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ath:AT5G51450

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence