iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019605

UUCD1 version

UUC-CaJ-00777

Ensembl Protein ID

ENSCJAP00000040936.1

UniProt Accession

F7HXF7; F7HXF7_CALJA

Genbank Protein ID

JAB10963.1; JAB15377.1; JAB38672.1; JAB38673.1

Protein Name

Suppressor of cytokine signaling 3

Genbank Nucleotide ID

ACFV01142776; GAMS01007759; GAMQ01003179; GAMQ01003178

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000022289.1	ENSCJAT00000043274.1	ENSCJAP00000040936.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	99.11	4.00e-113	404.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCTTCCA ATCCGCAGTT TCCCGGGATG CAGTAGCGGC CGCTGTGTGG AGGCCGCGAA 60
GCAGCTGCAG CCGCCGCCGC TCAGATCCAC GCTGGCTCCG TGCGCCATGG TCACCCACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

KEGG

cjc:100398838

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	96.44	6.00e-108	382.00
IUUC-Apl-003607	Anas platyrhynchos	81.78	7.00e-97	345.00
IUUC-Aca-005063	Anolis carolinensis	81.94	5.00e-103	366.00
IUUC-Ath-006990	Arabidopsis thaliana	32.94	8.00e-03	36.20
IUUC-Ame-010859	Astyanax mexicanus	58.26	8.00e-72	263.00
IUUC-Bta-012817	Bos taurus	90.83	3.00e-111	393.00
IUUC-Bra-017963	Brassica rapa	30.00	5.20e-02	32.70
IUUC-Cfa-021231	Canis familiaris	96.89	7.00e-109	385.00
IUUC-Cpo-022003	Cavia porcellus	90.79	3.00e-107	380.00
IUUC-Csa-023511	Chlorocebus sabaeus	99.11	1.00e-112	398.00
IUUC-Dre-028536	Danio rerio	60.00	5.00e-74	270.00
IUUC-Dno-029003	Dasypus novemcinctus	92.00	1.00e-109	388.00
IUUC-Eca-034205	Equus caballus	82.12	8.00e-68	249.00
IUUC-Fca-036317	Felis catus	95.07	5.00e-108	383.00
IUUC-Gmo-038777	Gadus morhua	63.89	8.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	82.67	6.00e-97	346.00
IUUC-Gac-041837	Gasterosteus aculeatus	55.46	5.00e-65	240.00
IUUC-Ggo-045620	Gorilla gorilla	99.11	1.00e-112	398.00
IUUC-Hsa-046909	Homo sapiens	99.11	1.00e-112	398.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	91.06	1.00e-111	395.00
IUUC-Lch-049510	Latimeria chalumnae	67.69	1.00e-84	305.00
IUUC-Loc-052863	Lepisosteus oculatus	62.61	3.00e-79	287.00
IUUC-Laf-054136	Loxodonta africana	92.11	5.00e-109	386.00
IUUC-Mcc-055383	Macaca mulatta	99.11	1.00e-112	398.00
IUUC-Meu-056153	Macropus eugenii	89.38	7.00e-111	392.00
IUUC-Mmr-061185	Microcebus murinus	94.25	6.00e-107	379.00
IUUC-Mdo-061819	Monodelphis domestica	90.22	3.00e-114	403.00
IUUC-Mmu-064231	Mus musculus	96.00	3.00e-119	420.00
IUUC-Mpu-066691	Mustela putorius furo	97.78	7.00e-109	385.00
IUUC-Mlu-067673	Myotis lucifugus	95.13	4.00e-116	410.00
IUUC-Ont-072406	Oreochromis niloticus	54.59	6.00e-68	249.00
IUUC-Oan-073249	Ornithorhynchus anatinus	75.11	3.00e-94	337.00
IUUC-Ocu-074935	Oryctolagus cuniculus	86.96	1.00e-31	127.00
IUUC-Ola-087373	Oryzias latipes	47.55	6.00e-48	183.00
IUUC-Oga-088041	Otolemur garnettii	92.89	2.00e-109	387.00
IUUC-Oar-089646	Ovis aries	89.52	4.00e-103	367.00
IUUC-Ptr-091502	Pan troglodytes	99.11	1.00e-112	398.00
IUUC-Pan-091934	Papio anubis	99.11	1.00e-112	398.00
IUUC-Pfo-096412	Poecilia formosa	42.79	3.00e-48	184.00
IUUC-Pab-098554	Pongo abelii	99.11	1.00e-112	398.00
IUUC-Rno-105874	Rattus norvegicus	95.56	7.00e-119	419.00
IUUC-Sha-107151	Sarcophilus harrisii	88.16	1.00e-110	392.00
IUUC-Ssc-115722	Sus scrofa	88.37	6.00e-65	239.00
IUUC-Tgu-117151	Taeniopygia guttata	83.11	8.00e-97	345.00
IUUC-Tru-118428	Takifugu rubripes	53.71	5.00e-68	249.00
IUUC-Tni-120590	Tetraodon nigroviridis	54.15	9.00e-67	245.00
IUUC-Ttr-129065	Tursiops truncatus	92.14	7.00e-111	392.00
IUUC-Xtr-132167	Xenopus tropicalis	66.22	4.00e-82	296.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence