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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Spo-108267
UUCD1 version UUC-ScP-00108
Ensembl Protein ID SPBC21D10.09c.1:pep
UniProt Accession O74349; LTN1_SCHPO
Genbank Protein ID CAA20765.1
Protein Name E3 ubiquitin-protein ligase listerin; RING-type E3 ubiquitin transferase listerin
Genbank Nucleotide ID CU329671
Gene Name rkr1; SPBC21D10.09c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPBC21D10.09c SPBC21D10.09c.1 SPBC21D10.09c.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
Mentha
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 7.00e-08 31.0 1558 1604
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledf........kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC++ +        k   +++ C H fha+Cl+kw     +ss++ rCPlCr
   Q: 1558 CAICYSVLsvertlpnK---RCGTCRHKFHASCLYKW----FKSSNSSRCPLCR 1604
           ****9988664443221...24669************....99**********8 PP
   
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to cdc48 recruitment for extraction and degradation of the incomplete translation product.
 E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to cdc48 recruitment for extraction and degradation of the incomplete translation product.
Protein Sequence
(Fasta)
MKKKSTDLYG RKNPGMQSMS GSFSSLQIAL DESSSNFSTI YEPPDLSGLD AEMIVIVKNL 60
QKRDIVTKCR ALQDLIQWND PSQFDNEQFL NALAVLFPRL SIEVERHVRL KIFVFMSVLS 120
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Protein Fasta Sequence


>IUUC-Spo-108267|E3,RING|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAAATAGTTA AGCTTTAAAG TATCAGTTTA TAAAGCATTG CATACCACAA TGAATTGCTT 60
AAAACAACGT TATCAATAAC CTATGATAAC GTCGGACAGA CTGATATCTG ATTTCCTTTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108267|E3,RING|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF13639--zf-RING_2
SMART

SM00184--RING
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:1990112--C:RQC complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1990116--P:ribosome-associated ubiquitin-dependent protein catabolic process
KEGG spo:SPBC21D10.09c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000717 Aegilops tauschii 39.71 6.00e-44 171.00
IUUC-Aml-002311 Ailuropoda melanoleuca 35.93 5.00e-46 178.00
IUUC-Atr-002905 Amborella trichopoda 35.16 3.00e-43 169.00
IUUC-Apl-003323 Anas platyrhynchos 41.86 7.00e-42 164.00
IUUC-Aca-004616 Anolis carolinensis 40.53 5.00e-46 178.00
IUUC-Aly-006145 Arabidopsis lyrata 35.21 4.00e-38 152.00
IUUC-Ath-006844 Arabidopsis thaliana 36.62 2.00e-40 159.00
IUUC-Ago-007750 Ashbya gossypii 26.88 5.00e-52 198.00
IUUC-Acl-008369 Aspergillus clavatus 29.78 1.00e-64 240.00
IUUC-Afl-008540 Aspergillus flavus 29.07 7.00e-61 228.00
IUUC-Afu-009089 Aspergillus fumigatus 28.74 2.00e-58 219.00
IUUC-Ani-009292 Aspergillus nidulans 29.43 3.00e-64 239.00
IUUC-Ang-009715 Aspergillus niger 35.49 2.00e-54 206.00
IUUC-Aor-009887 Aspergillus oryzae 29.60 3.00e-61 228.00
IUUC-Ate-010308 Aspergillus terreus 28.09 1.00e-50 194.00
IUUC-Ame-011345 Astyanax mexicanus 43.54 2.00e-45 176.00
IUUC-Bgr-012196 Blumeria graminis 22.62 6.00e-29 121.00
IUUC-Bta-012535 Bos taurus 35.93 2.00e-43 170.00
IUUC-Bci-013630 Botrytis cinerea 28.53 2.00e-70 259.00
IUUC-Bdi-014142 Brachypodium distachyon 37.80 6.00e-42 165.00
IUUC-Bol-015333 Brassica oleracea 36.15 3.00e-39 156.00
IUUC-Cel-018254 Caenorhabditis elegans 30.50 5.00e-29 122.00
IUUC-Cja-019469 Callithrix jacchus 36.27 2.00e-46 180.00
IUUC-Cfa-020640 Canis familiaris 35.81 4.00e-45 175.00
IUUC-Cpo-021322 Cavia porcellus 36.61 1.00e-46 181.00
IUUC-Cre-022677 Chlamydomonas reinhardtii 45.90 1.00e-29 122.00
IUUC-Csa-024234 Chlorocebus sabaeus 36.27 1.00e-46 181.00
IUUC-Cho-024709 Choloepus hoffmanni 35.59 3.00e-44 172.00
IUUC-Csv-026100 Ciona savignyi 36.49 6.00e-38 151.00
IUUC-Cgl-026598 Colletotrichum gloeosporioides 53.25 3.00e-26 107.00
IUUC-Cne-026789 Cryptococcus neoformans 27.17 4.00e-54 205.00
IUUC-Cme-027135 Cyanidioschyzon merolae 40.54 1.00e-12 67.80
IUUC-Dre-027405 Danio rerio 41.63 5.00e-44 171.00
IUUC-Dno-029874 Dasypus novemcinctus 32.14 4.00e-30 125.00
IUUC-Dor-030589 Dipodomys ordii 35.93 3.00e-44 172.00
IUUC-Dse-031427 Dothistroma septosporum 30.69 8.00e-73 267.00
IUUC-Dme-031827 Drosophila melanogaster 25.51 2.00e-31 130.00
IUUC-Ete-032459 Echinops telfairi 35.25 7.00e-46 177.00
IUUC-Eca-033218 Equus caballus 35.93 4.00e-46 179.00
IUUC-Eeu-035299 Erinaceus europaeus 23.11 2.00e-05 44.30
IUUC-Fca-036081 Felis catus 35.59 4.00e-46 178.00
IUUC-Fal-037561 Ficedula albicollis 35.35 2.00e-42 166.00
IUUC-Fox-037930 Fusarium oxysporum 27.88 2.00e-64 239.00
IUUC-Fso-038413 Fusarium solani 25.54 1.00e-59 223.00
IUUC-Gmo-039359 Gadus morhua 41.63 2.00e-45 176.00
IUUC-Ggr-039744 Gaeumannomyces graminis 24.62 3.00e-58 219.00
IUUC-Gga-041175 Gallus gallus 41.40 1.00e-41 164.00
IUUC-Gac-041943 Gasterosteus aculeatus 41.15 1.00e-43 171.00
IUUC-Gma-043888 Glycine max 38.50 4.00e-43 169.00
IUUC-Ggo-044912 Gorilla gorilla 25.19 4.00e-09 55.50
IUUC-Hsa-047016 Homo sapiens 35.93 6.00e-46 178.00
IUUC-Hvu-047059 Hordeum vulgare 39.23 2.00e-43 169.00
IUUC-Itr-048789 Ictidomys tridecemlineatus 36.27 5.00e-47 181.00
IUUC-Kpa-049133 Komagataella pastoris 38.10 4.00e-65 241.00
IUUC-Lch-049879 Latimeria chalumnae 32.33 1.00e-26 114.00
IUUC-Lpe-051455 Leersia perrieri 39.27 7.00e-45 174.00
IUUC-Loc-052799 Lepisosteus oculatus 37.29 2.00e-47 183.00
IUUC-Lma-052972 Leptosphaeria maculans 28.76 2.00e-62 233.00
IUUC-Laf-053479 Loxodonta africana 35.93 2.00e-46 180.00
IUUC-Mcc-055120 Macaca mulatta 36.27 1.00e-46 181.00
IUUC-Meu-055932 Macropus eugenii 33.23 2.00e-45 176.00
IUUC-Mor-057209 Magnaporthe oryzae 26.27 7.00e-61 227.00
IUUC-Mpo-057581 Magnaporthe poae 24.54 1.00e-52 200.00
IUUC-Mtr-058499 Medicago truncatula 36.57 6.00e-42 165.00
IUUC-Mla-059169 Melampsora laricipopulina 57.58 5.00e-46 174.00
IUUC-Mga-059800 Meleagris gallopavo 41.40 1.00e-41 164.00
IUUC-Mvi-060350 Microbotryum violaceum 28.64 2.00e-62 233.00
IUUC-Mmr-061548 Microcebus murinus 35.93 3.00e-46 179.00
IUUC-Mdo-062405 Monodelphis domestica 34.38 7.00e-46 178.00
IUUC-Mmu-064389 Mus musculus 35.93 2.00e-46 179.00
IUUC-Mac-064596 Musa acuminata 37.04 1.00e-42 167.00
IUUC-Mpu-065687 Mustela putorius furo 35.93 3.00e-46 179.00
IUUC-Mlu-067591 Myotis lucifugus 41.63 2.00e-44 173.00
IUUC-Nfi-068298 Neosartorya fischeri 35.49 2.00e-60 226.00
IUUC-Ncr-068876 Neurospora crassa 25.69 1.00e-62 233.00
IUUC-Nle-069799 Nomascus leucogenys 35.59 4.00e-46 179.00
IUUC-Opr-071155 Ochotona princeps 35.49 5.00e-47 181.00
IUUC-Ont-071290 Oreochromis niloticus 41.15 9.00e-45 174.00
IUUC-Ocu-074947 Oryctolagus cuniculus 36.27 1.00e-46 180.00
IUUC-Oba-075986 Oryza barthii 39.27 1.00e-45 177.00
IUUC-Obr-076304 Oryza brachyantha 38.89 2.00e-44 173.00
IUUC-Ogl-077600 Oryza glaberrima 39.27 1.00e-45 177.00
IUUC-Ogu-078079 Oryza glumaepatula 39.27 1.00e-45 177.00
IUUC-Oin-079935 Oryza indica 39.27 2.00e-45 177.00
IUUC-Olo-080897 Oryza longistaminata 39.27 1.00e-45 177.00
IUUC-Ome-081777 Oryza meridionalis 39.27 2.00e-45 177.00
IUUC-Oni-082298 Oryza nivara 39.27 1.00e-45 177.00
IUUC-Opu-083156 Oryza punctata 39.27 2.00e-45 176.00
IUUC-Oru-085243 Oryza rufipogon 39.27 1.00e-45 177.00
IUUC-Osa-086219 Oryza sativa 39.27 2.00e-45 177.00
IUUC-Ola-087202 Oryzias latipes 40.67 1.00e-44 174.00
IUUC-Olu-087800 Ostreococcus lucimarinus 39.30 2.00e-40 159.00
IUUC-Oga-088962 Otolemur garnettii 36.27 1.00e-46 181.00
IUUC-Oar-089858 Ovis aries 35.67 3.00e-46 179.00
IUUC-Ptr-090958 Pan troglodytes 36.27 1.00e-46 180.00
IUUC-Pan-092712 Papio anubis 35.59 3.00e-46 179.00
IUUC-Psi-093557 Pelodiscus sinensis 34.81 6.00e-47 181.00
IUUC-Pma-094199 Petromyzon marinus 34.76 3.00e-21 92.00
IUUC-Pno-094947 Phaeosphaeria nodorum 28.77 2.00e-65 243.00
IUUC-Ppa-095258 Physcomitrella patens 39.23 2.00e-45 176.00
IUUC-Pfo-097035 Poecilia formosa 42.11 2.00e-45 177.00
IUUC-Pab-097897 Pongo abelii 36.27 1.00e-46 181.00
IUUC-Pop-099487 Populus trichocarpa 36.45 7.00e-40 158.00
IUUC-Pca-100688 Procavia capensis 46.43 1.00e-33 137.00
IUUC-Ppe-101821 Prunus persica 36.92 4.00e-41 162.00
IUUC-Pva-102632 Pteropus vampyrus 35.23 4.00e-46 179.00
IUUC-Pgr-103311 Puccinia graminis 30.81 1.00e-64 240.00
IUUC-Ptt-103825 Puccinia triticina 30.78 7.00e-56 211.00
IUUC-Pte-104036 Pyrenophora teres 32.58 2.00e-61 229.00
IUUC-Pyt-104460 Pyrenophora triticirepentis 32.33 2.00e-60 226.00
IUUC-Rno-104852 Rattus norvegicus 36.61 2.00e-47 183.00
IUUC-Sce-106305 Saccharomyces cerevisiae 28.74 3.00e-58 219.00
IUUC-Sja-107896 Schizosaccharomyces japonicus 32.94 0.00e+00 798.00
IUUC-Smo-109180 Selaginella moellendorffii 39.02 3.00e-43 169.00
IUUC-Sit-110615 Setaria italica 38.71 2.00e-43 170.00
IUUC-Sly-111861 Solanum lycopersicum 36.07 2.00e-42 166.00
IUUC-Stu-112373 Solanum tuberosum 36.92 2.00e-42 166.00
IUUC-Sar-113666 Sorex araneus 35.93 4.00e-47 182.00
IUUC-Sbi-114597 Sorghum bicolor 38.43 2.00e-43 170.00
IUUC-Sre-114965 Sporisorium reilianum 28.73 2.00e-64 240.00
IUUC-Ssc-115866 Sus scrofa 36.27 2.00e-46 180.00
IUUC-Tgu-117521 Taeniopygia guttata 35.25 4.00e-42 165.00
IUUC-Tru-117803 Takifugu rubripes 39.11 9.00e-46 177.00
IUUC-Tsy-119135 Tarsius syrichta 34.97 5.00e-41 162.00
IUUC-Tni-119807 Tetraodon nigroviridis 39.11 2.00e-43 169.00
IUUC-Tca-121036 Theobroma cacao 37.85 2.00e-42 167.00
IUUC-Tre-121942 Trichoderma reesei 26.08 9.00e-56 211.00
IUUC-Tvi-122453 Trichoderma virens 32.68 7.00e-52 197.00
IUUC-Tae-123061 Triticum aestivum 39.71 6.00e-44 171.00
IUUC-Tur-126021 Triticum urartu 39.23 2.00e-43 169.00
IUUC-Tme-126889 Tuber melanosporum 32.61 3.00e-79 289.00
IUUC-Tbe-127297 Tupaia belangeri 34.93 5.00e-27 115.00
IUUC-Ttr-128745 Tursiops truncatus 36.00 2.00e-46 179.00
IUUC-Uma-129552 Ustilago maydis 28.45 2.00e-65 243.00
IUUC-Vda-129838 Verticillium dahliae 25.81 2.00e-63 236.00
IUUC-Vpa-130567 Vicugna pacos 36.27 3.00e-46 179.00
IUUC-Vvi-131418 Vitis vinifera 37.85 9.00e-43 167.00
IUUC-Xtr-132926 Xenopus tropicalis 31.41 3.00e-43 169.00
IUUC-Xma-134278 Xiphophorus maculatus 42.11 1.00e-45 177.00
IUUC-Yli-134476 Yarrowia lipolytica 42.07 1.00e-70 260.00
IUUC-Zma-135611 Zea mays 39.35 3.00e-44 172.00
Created Date 25-Jun-2017

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