iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.60e-23	80.2	122	152
UBD/Beta-Prp	1.50e-54	186.1	120	388

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H++ v+c +f +d  ++++G+ D +ik++++
   Q: 122  HKSVVRCARFsPDgMFFATGGADTSIKLFEV 152
           9**********997889************97 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.. 91
           ++hksv++c  fspd+ ++atg++d +ik+++v + k            +r++++h +++++++f+p++ il+++++D+ ik +d+s+ +  +++k  
   Q: 120  SEHKSVVRCARFSPDGMFFATGGADTSIKLFEVPKVKQmisgdtqarplIRTFYDHAEPINDLDFHPRSTILISSAKDNCIKFFDFSKTTAKRAFKvf 217
           46889****************************998889************************************************88888877777 PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh.tdsvys 185
           + +++v+s+sf+psg++l++G+++ + +++d++t+qc+     ++sg +g++n v+++++g++++++s+D+++rl+d  ++k++r    +h ++ v+s
   Q: 218  QDTHNVRSISFHPSGEFLLAGTDHPIPHLYDVNTYQCFLPsnfPDSGVSGAINQVRYSSTGSIYITASKDGAIRLFDGVSAKCVRSIGNAHgKSEVTS 315
           8*************************************9999*********************************************66662567999 PP
   S: 186  lsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiri..Wdlrsgd 255
             f++++++++s ++d+tvklw++ +g++v+++ g ++  ++ ++   + +e+++s   + s  +  Wd r+ d
   Q: 316  AVFTKDQRFVLSSGKDSTVKLWEIGSGRMVKEYLGAKRVKLRSQAIfnDTEEFVISID-EASNEVvtWDARTAD 388
           ***********************************88666555544336666666664.55555445**99987 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

One of the multiple factors required for polyadenylation and 3'-end cleavage of pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA.

Protein Sequence
(Fasta)

MGNSGDLEQA LQDGNIFRQL NALIVAHLRH HNLSQVASAV ASATMTPLNI EVPPNRLLEL 60
VAKGLAAENN GTLRGVSSSV LLPSSYGSIT TPRTASIDFS VNHAKGSSKT IPKHESKTLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCATGTTGAT CTTTGTTTCT GAAGAGGAGG AGGAAGAAGA CGATGGTTGA CACTTGACAG 60
AGTAAGCTCA GAAATGGCGA CTCTGGTTTC GAATTGAACT TGTGAGGAAG GTTTTTAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006397--P:mRNA processing

KEGG

ath:AT5G60940

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002163	Ailuropoda melanoleuca	37.97	1.00e-80	292.00
IUUC-Atr-002687	Amborella trichopoda	56.01	9.00e-156	542.00
IUUC-Apl-003438	Anas platyrhynchos	37.50	4.00e-81	294.00
IUUC-Aca-005178	Anolis carolinensis	37.74	4.00e-81	294.00
IUUC-Aly-005791	Arabidopsis lyrata	96.97	0.00e+00	844.00
IUUC-Ame-011217	Astyanax mexicanus	47.19	1.00e-69	255.00
IUUC-Bta-012619	Bos taurus	37.50	2.00e-80	292.00
IUUC-Bdi-014515	Brachypodium distachyon	61.72	3.00e-152	530.00
IUUC-Bra-017450	Brassica rapa	81.00	0.00e+00	728.00
IUUC-Cel-018151	Caenorhabditis elegans	40.43	8.00e-69	253.00
IUUC-Cja-019304	Callithrix jacchus	38.21	4.00e-81	294.00
IUUC-Cfa-020208	Canis familiaris	37.97	1.00e-80	292.00
IUUC-Cpo-022245	Cavia porcellus	37.97	1.00e-80	292.00
IUUC-Csa-023066	Chlorocebus sabaeus	38.21	4.00e-81	294.00
IUUC-Cho-024770	Choloepus hoffmanni	43.29	6.00e-78	283.00
IUUC-Cin-025621	Ciona intestinalis	36.67	1.00e-67	249.00
IUUC-Csv-026071	Ciona savignyi	41.44	5.00e-75	274.00
IUUC-Dre-028254	Danio rerio	37.12	1.00e-78	286.00
IUUC-Dno-029903	Dasypus novemcinctus	37.97	1.00e-80	292.00
IUUC-Dor-030423	Dipodomys ordii	37.97	2.00e-80	292.00
IUUC-Dme-031993	Drosophila melanogaster	38.20	2.00e-69	255.00
IUUC-Eca-033316	Equus caballus	37.97	1.00e-80	292.00
IUUC-Eeu-035001	Erinaceus europaeus	37.83	8.00e-80	290.00
IUUC-Fca-036447	Felis catus	37.97	1.00e-80	292.00
IUUC-Fal-037601	Ficedula albicollis	37.50	4.00e-81	294.00
IUUC-Gmo-038531	Gadus morhua	36.47	6.00e-74	270.00
IUUC-Gga-040869	Gallus gallus	37.50	5.00e-81	294.00
IUUC-Gac-042380	Gasterosteus aculeatus	38.26	2.00e-78	285.00
IUUC-Gma-043478	Glycine max	67.67	6.00e-180	622.00
IUUC-Ggo-045302	Gorilla gorilla	38.21	4.00e-81	294.00
IUUC-Hsa-045678	Homo sapiens	38.21	4.00e-81	294.00
IUUC-Hvu-047301	Hordeum vulgare	61.65	7.00e-149	519.00
IUUC-Itr-048259	Ictidomys tridecemlineatus	37.97	1.00e-80	292.00
IUUC-Lch-050319	Latimeria chalumnae	37.03	5.00e-79	287.00
IUUC-Lpe-051440	Leersia perrieri	47.65	2.00e-127	448.00
IUUC-Loc-052035	Lepisosteus oculatus	37.74	7.00e-80	290.00
IUUC-Laf-054275	Loxodonta africana	37.97	1.00e-80	292.00
IUUC-Mcc-055857	Macaca mulatta	33.25	2.00e-61	229.00
IUUC-Mtr-058667	Medicago truncatula	64.08	1.00e-167	582.00
IUUC-Mga-059710	Meleagris gallopavo	37.50	5.00e-81	294.00
IUUC-Mmr-060604	Microcebus murinus	37.97	1.00e-80	292.00
IUUC-Mdo-062953	Monodelphis domestica	37.50	2.00e-80	292.00
IUUC-Mmu-064292	Mus musculus	37.74	2.00e-80	292.00
IUUC-Mac-064568	Musa acuminata	70.43	2.00e-143	501.00
IUUC-Mpu-066294	Mustela putorius furo	45.97	1.00e-53	202.00
IUUC-Mlu-067279	Myotis lucifugus	38.06	1.00e-80	292.00
IUUC-Nle-069322	Nomascus leucogenys	38.21	4.00e-81	294.00
IUUC-Opr-070580	Ochotona princeps	37.50	2.00e-80	291.00
IUUC-Ont-072554	Oreochromis niloticus	37.59	1.00e-79	289.00
IUUC-Oan-072856	Ornithorhynchus anatinus	37.26	5.00e-80	290.00
IUUC-Ocu-074150	Oryctolagus cuniculus	34.28	1.00e-64	239.00
IUUC-Oba-075585	Oryza barthii	55.29	3.00e-141	494.00
IUUC-Obr-076069	Oryza brachyantha	60.09	4.00e-144	503.00
IUUC-Ogl-077045	Oryza glaberrima	61.01	2.00e-155	541.00
IUUC-Ogu-078697	Oryza glumaepatula	60.61	3.00e-147	515.00
IUUC-Oin-080119	Oryza indica	61.01	2.00e-155	541.00
IUUC-Olo-081093	Oryza longistaminata	50.64	2.00e-86	313.00
IUUC-Ome-081718	Oryza meridionalis	52.98	1.00e-124	439.00
IUUC-Oni-082072	Oryza nivara	55.29	3.00e-141	494.00
IUUC-Opu-084080	Oryza punctata	54.15	2.00e-118	417.00
IUUC-Oru-085070	Oryza rufipogon	57.24	3.00e-140	492.00
IUUC-Osa-086149	Oryza sativa	61.01	2.00e-155	541.00
IUUC-Ola-086697	Oryzias latipes	37.83	3.00e-80	291.00
IUUC-Oga-088697	Otolemur garnettii	37.97	1.00e-80	292.00
IUUC-Oar-089774	Ovis aries	37.97	2.00e-80	292.00
IUUC-Ptr-090924	Pan troglodytes	38.21	4.00e-81	294.00
IUUC-Pan-092373	Papio anubis	38.21	5.00e-81	294.00
IUUC-Psi-094001	Pelodiscus sinensis	37.50	2.00e-80	292.00
IUUC-Pma-094274	Petromyzon marinus	36.47	3.00e-74	271.00
IUUC-Ppa-095562	Physcomitrella patens	60.42	6.00e-155	539.00
IUUC-Pfo-097235	Poecilia formosa	37.59	2.00e-79	288.00
IUUC-Pab-098608	Pongo abelii	38.21	4.00e-81	294.00
IUUC-Pca-100268	Procavia capensis	37.50	2.00e-80	292.00
IUUC-Ppe-101425	Prunus persica	68.93	6.00e-177	612.00
IUUC-Pva-103183	Pteropus vampyrus	37.97	1.00e-80	292.00
IUUC-Rno-105097	Rattus norvegicus	37.74	2.00e-80	292.00
IUUC-Sha-107642	Sarcophilus harrisii	37.50	2.00e-80	292.00
IUUC-Smo-108680	Selaginella moellendorffii	57.65	2.00e-143	501.00
IUUC-Sit-110471	Setaria italica	62.94	2.00e-158	551.00
IUUC-Sly-111143	Solanum lycopersicum	65.16	4.00e-89	320.00
IUUC-Stu-111926	Solanum tuberosum	72.22	6.00e-72	261.00
IUUC-Sar-112947	Sorex araneus	44.35	1.00e-61	228.00
IUUC-Sbi-113769	Sorghum bicolor	61.92	2.00e-152	531.00
IUUC-Ssc-115736	Sus scrofa	37.97	1.00e-80	292.00
IUUC-Tgu-117457	Taeniopygia guttata	37.50	4.00e-81	294.00
IUUC-Tru-117760	Takifugu rubripes	37.59	3.00e-79	288.00
IUUC-Tsy-118943	Tarsius syrichta	37.26	2.00e-76	278.00
IUUC-Tni-120081	Tetraodon nigroviridis	37.12	9.00e-79	286.00
IUUC-Tca-121190	Theobroma cacao	71.86	0.00e+00	635.00
IUUC-Tae-123709	Triticum aestivum	61.94	1.00e-151	528.00
IUUC-Tur-126329	Triticum urartu	58.81	5.00e-140	490.00
IUUC-Tbe-127878	Tupaia belangeri	37.97	6.00e-80	290.00
IUUC-Ttr-128985	Tursiops truncatus	37.97	1.00e-80	292.00
IUUC-Vpa-130147	Vicugna pacos	37.97	2.00e-80	292.00
IUUC-Vvi-130935	Vitis vinifera	66.59	2.00e-176	611.00
IUUC-Xtr-132482	Xenopus tropicalis	37.26	9.00e-80	290.00
IUUC-Xma-133929	Xiphophorus maculatus	37.59	2.00e-79	288.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence