iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aly-006522

Ensembl Protein ID

Al_scaffold_0007_1340

UniProt Accession

D7MDQ7; D7MDQ7_ARALL

Genbank Protein ID

EFH45794.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

GL348719

Gene Name

ARALYDRAFT_657285

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Al_scaffold_0007_1340	Al_scaffold_0007_1340	Al_scaffold_0007_1340

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.69	0.00e+00	665.00	IUUC-Ath-007192
E3 activity/RING/RING	34.25	7.00e-36	147.00	IUUC-Dme-031700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis lyrata

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

METDSMECVS STGNEIHQNG NGHQSYQFSS TKTHGGAAAA AVVTNIVGPT ATAPATSVYE 60
LLECPVCTYS MYPPIHQCHN GHTLCSTCKV RVHNRCPTCR QELGDIRCLA LEKVAESLEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGACAG ATAGTATGGA GTGCGTCTCG TCTACGGGGA ATGAGATCCA TCAGAACGGT 60
AATGGCCACC AATCTTACCA ATTCTCTTCG ACGAAGACTC ACGGCGGTGC CGCAGCGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aly:ARALYDRAFT_657285

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003118	Amborella trichopoda	81.82	6.00e-133	466.00
IUUC-Apl-003813	Anas platyrhynchos	37.35	2.00e-41	162.00
IUUC-Ath-007192	Arabidopsis thaliana	99.69	0.00e+00	665.00
IUUC-Ame-011196	Astyanax mexicanus	37.96	8.00e-42	163.00
IUUC-Bdi-014729	Brachypodium distachyon	87.64	5.00e-150	523.00
IUUC-Bol-015983	Brassica oleracea	90.18	5.00e-173	599.00
IUUC-Bra-016910	Brassica rapa	90.49	3.00e-175	606.00
IUUC-Cel-018320	Caenorhabditis elegans	33.33	4.00e-36	144.00
IUUC-Cho-024933	Choloepus hoffmanni	36.14	4.00e-37	147.00
IUUC-Cin-025674	Ciona intestinalis	35.27	2.00e-39	154.00
IUUC-Csv-026233	Ciona savignyi	34.94	2.00e-39	154.00
IUUC-Dre-028041	Danio rerio	37.96	9.00e-42	163.00
IUUC-Dor-030489	Dipodomys ordii	31.35	1.00e-19	88.60
IUUC-Dme-031700	Drosophila melanogaster	35.08	1.00e-33	135.00
IUUC-Eca-033536	Equus caballus	37.35	2.00e-41	162.00
IUUC-Gmo-039091	Gadus morhua	35.69	2.00e-36	145.00
IUUC-Gga-040269	Gallus gallus	37.35	2.00e-41	162.00
IUUC-Gac-042282	Gasterosteus aculeatus	37.35	7.00e-42	163.00
IUUC-Gma-042926	Glycine max	81.20	7.00e-133	465.00
IUUC-Lch-049504	Latimeria chalumnae	37.35	2.00e-41	162.00
IUUC-Laf-053668	Loxodonta africana	37.35	2.00e-41	162.00
IUUC-Meu-055922	Macropus eugenii	35.74	4.00e-36	144.00
IUUC-Mtr-058699	Medicago truncatula	80.67	1.00e-156	544.00
IUUC-Mdo-061971	Monodelphis domestica	36.55	2.00e-37	148.00
IUUC-Mac-065670	Musa acuminata	78.22	6.00e-151	525.00
IUUC-Mpu-066331	Mustela putorius furo	37.70	4.00e-42	164.00
IUUC-Opr-070341	Ochotona princeps	26.58	2.00e-12	65.50
IUUC-Ont-071849	Oreochromis niloticus	37.35	6.00e-42	163.00
IUUC-Oan-073701	Ornithorhynchus anatinus	24.83	1.00e-11	62.40
IUUC-Oba-075289	Oryza barthii	88.67	9.00e-139	485.00
IUUC-Obr-076037	Oryza brachyantha	82.81	1.00e-131	461.00
IUUC-Ogl-077148	Oryza glaberrima	82.81	1.00e-131	461.00
IUUC-Ogu-078042	Oryza glumaepatula	82.81	7.00e-132	462.00
IUUC-Oin-079325	Oryza indica	82.81	1.00e-131	461.00
IUUC-Olo-080244	Oryza longistaminata	82.81	4.00e-132	464.00
IUUC-Oni-082163	Oryza nivara	82.81	1.00e-131	461.00
IUUC-Oru-084833	Oryza rufipogon	82.81	1.00e-131	461.00
IUUC-Osa-085316	Oryza sativa	82.81	1.00e-131	461.00
IUUC-Ola-086814	Oryzias latipes	37.35	7.00e-42	163.00
IUUC-Oga-088114	Otolemur garnettii	36.82	8.00e-43	166.00
IUUC-Pma-094387	Petromyzon marinus	36.08	9.00e-42	162.00
IUUC-Pfo-097134	Poecilia formosa	37.35	7.00e-42	163.00
IUUC-Pop-100033	Populus trichocarpa	80.72	2.00e-156	544.00
IUUC-Pca-100328	Procavia capensis	35.74	8.00e-35	140.00
IUUC-Ppe-101960	Prunus persica	80.48	4.00e-158	550.00
IUUC-Pva-103132	Pteropus vampyrus	24.54	4.00e-11	60.80
IUUC-Sit-110245	Setaria italica	83.59	5.00e-132	463.00
IUUC-Sly-111259	Solanum lycopersicum	75.68	1.00e-146	511.00
IUUC-Stu-112571	Solanum tuberosum	76.28	2.00e-149	521.00
IUUC-Sbi-114035	Sorghum bicolor	81.99	3.00e-132	463.00
IUUC-Ssc-116441	Sus scrofa	36.14	4.00e-37	147.00
IUUC-Tgu-116579	Taeniopygia guttata	37.35	2.00e-41	162.00
IUUC-Tru-118250	Takifugu rubripes	36.58	5.00e-40	157.00
IUUC-Tsy-119548	Tarsius syrichta	31.96	2.00e-08	51.60
IUUC-Tni-120488	Tetraodon nigroviridis	37.90	2.00e-39	155.00
IUUC-Tca-121517	Theobroma cacao	81.66	5.00e-160	556.00
IUUC-Tur-126259	Triticum urartu	80.46	3.00e-130	457.00
IUUC-Vpa-130799	Vicugna pacos	32.16	2.00e-18	84.70
IUUC-Xma-133670	Xiphophorus maculatus	37.35	7.00e-42	163.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence