iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008370

Ensembl Protein ID

CADACLAP00007393

UniProt Accession

A1CU75; CMR1_ASPCL

Genbank Protein ID

EAW06862.1

Protein Name

DNA damage-binding protein cmr1

Genbank Nucleotide ID

DS027060

Gene Name

ACLA_085580

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00007584	CADACLAT00007584	CADACLAP00007393

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-12	46.7	355	379

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 11   f.sd..tllvsGsdDgtikvWDlrt 32
           + ++  ++++++s D t+++WDlr+
   Q: 355  LyPThpHFFATASLDRTMRLWDLRK 379
           353334679*************986 PP

Organism

Aspergillus clavatus

Functional Description
(View)

DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

Protein Sequence
(Fasta)

MGTDSTELSE FEKQRLANIA ERDALLKKLT LDAQSSGIFP PKLARSSPVS QTKPKKKPAP 60
KKIKKEGEAP VARRMSSRLR GIAAESEVAK RKAEEHYEAV QQAERAKRVR KSDAFSFSEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCACCG ACAGCACCGA GCTCTCAGAG TTCGAAAAGC AGCGGCTCGC CAACATCGCC 60
GAGCGCGATG CGCTGCTCAA GAAGCTCACC CTGGACGCCC AGTCATCCGG CATCTTCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0238--DNA-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR033052--Cmr1/WDR76
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000790--C:nuclear chromatin
GO:0034399--C:nuclear periphery
GO:0003677--F:DNA binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:2000001--P:regulation of DNA damage checkpoint

KEGG

act:ACLA_085580

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000577	Aegilops tauschii	31.13	5.00e-10	56.60
IUUC-Atr-002605	Amborella trichopoda	21.98	2.00e-17	81.60
IUUC-Apl-003441	Anas platyrhynchos	24.82	4.00e-26	110.00
IUUC-Aca-004241	Anolis carolinensis	27.89	2.00e-29	121.00
IUUC-Aly-005444	Arabidopsis lyrata	27.73	4.00e-29	120.00
IUUC-Ath-007550	Arabidopsis thaliana	26.89	1.00e-27	116.00
IUUC-Ago-007715	Ashbya gossypii	30.27	3.00e-56	211.00
IUUC-Afl-008586	Aspergillus flavus	81.36	0.00e+00	819.00
IUUC-Afu-008907	Aspergillus fumigatus	88.14	0.00e+00	893.00
IUUC-Ani-009415	Aspergillus nidulans	77.71	0.00e+00	797.00
IUUC-Ang-009597	Aspergillus niger	67.49	9.00e-144	501.00
IUUC-Aor-010197	Aspergillus oryzae	81.17	0.00e+00	819.00
IUUC-Ate-010280	Aspergillus terreus	79.40	0.00e+00	836.00
IUUC-Bgr-012236	Blumeria graminis	47.00	2.00e-132	464.00
IUUC-Bta-013059	Bos taurus	25.72	3.00e-29	121.00
IUUC-Bci-013796	Botrytis cinerea	51.13	5.00e-143	499.00
IUUC-Bdi-015040	Brachypodium distachyon	29.91	2.00e-24	104.00
IUUC-Bol-015934	Brassica oleracea	26.42	3.00e-22	97.40
IUUC-Bra-018032	Brassica rapa	26.82	8.00e-25	106.00
IUUC-Cja-019043	Callithrix jacchus	24.21	2.00e-31	128.00
IUUC-Cfa-021103	Canis familiaris	24.41	2.00e-27	115.00
IUUC-Cpo-021508	Cavia porcellus	26.70	7.00e-30	123.00
IUUC-Cre-022967	Chlamydomonas reinhardtii	22.00	2.00e-11	62.40
IUUC-Csa-023555	Chlorocebus sabaeus	24.47	8.00e-30	123.00
IUUC-Cin-025651	Ciona intestinalis	24.17	1.00e-22	99.80
IUUC-Cgl-026604	Colletotrichum gloeosporioides	47.73	5.00e-126	442.00
IUUC-Cne-027093	Cryptococcus neoformans	29.02	4.00e-39	154.00
IUUC-Cme-027238	Cyanidioschyzon merolae	26.13	3.00e-21	94.70
IUUC-Dre-027441	Danio rerio	26.28	4.00e-28	117.00
IUUC-Dno-029575	Dasypus novemcinctus	24.87	6.00e-27	114.00
IUUC-Dor-030554	Dipodomys ordii	24.54	1.00e-28	119.00
IUUC-Dse-031299	Dothistroma septosporum	53.56	3.00e-147	513.00
IUUC-Ete-032716	Echinops telfairi	24.57	2.00e-15	75.50
IUUC-Eca-034027	Equus caballus	25.75	5.00e-17	80.90
IUUC-Eeu-035234	Erinaceus europaeus	24.40	7.00e-09	53.90
IUUC-Fca-035892	Felis catus	24.94	3.00e-26	111.00
IUUC-Fal-036986	Ficedula albicollis	24.46	1.00e-24	105.00
IUUC-Fox-037750	Fusarium oxysporum	50.54	2.00e-126	443.00
IUUC-Fso-038198	Fusarium solani	49.47	1.00e-118	417.00
IUUC-Gga-040479	Gallus gallus	26.53	1.00e-15	76.30
IUUC-Gac-042043	Gasterosteus aculeatus	27.07	2.00e-22	98.60
IUUC-Gma-043913	Glycine max	25.09	6.00e-31	126.00
IUUC-Ggo-045290	Gorilla gorilla	25.00	2.00e-32	131.00
IUUC-Hsa-047021	Homo sapiens	25.26	4.00e-32	130.00
IUUC-Hvu-047193	Hordeum vulgare	29.36	3.00e-24	104.00
IUUC-Itr-047914	Ictidomys tridecemlineatus	26.14	6.00e-31	127.00
IUUC-Kpa-049275	Komagataella pastoris	31.17	7.00e-71	259.00
IUUC-Lch-049718	Latimeria chalumnae	24.65	5.00e-28	117.00
IUUC-Lpe-051708	Leersia perrieri	29.27	1.00e-23	102.00
IUUC-Loc-052565	Lepisosteus oculatus	25.47	3.00e-29	121.00
IUUC-Lma-053276	Leptosphaeria maculans	55.39	2.00e-157	547.00
IUUC-Laf-053970	Loxodonta africana	25.83	5.00e-33	134.00
IUUC-Mcc-054740	Macaca mulatta	24.21	1.00e-29	122.00
IUUC-Meu-056546	Macropus eugenii	29.55	3.00e-12	65.10
IUUC-Mtr-058451	Medicago truncatula	24.39	6.00e-30	123.00
IUUC-Mla-059117	Melampsora laricipopulina	35.84	1.00e-53	202.00
IUUC-Mga-059328	Meleagris gallopavo	26.74	4.00e-22	97.10
IUUC-Mvi-060555	Microbotryum violaceum	30.29	2.00e-36	145.00
IUUC-Mmr-061520	Microcebus murinus	24.93	8.00e-31	126.00
IUUC-Mdo-062812	Monodelphis domestica	24.08	1.00e-32	132.00
IUUC-Mmu-064011	Mus musculus	24.06	1.00e-23	103.00
IUUC-Mac-065598	Musa acuminata	20.05	2.00e-07	48.50
IUUC-Mpu-066486	Mustela putorius furo	25.07	2.00e-27	115.00
IUUC-Mlu-067721	Myotis lucifugus	25.00	4.00e-20	90.90
IUUC-Nfi-068314	Neosartorya fischeri	87.57	0.00e+00	885.00
IUUC-Ncr-068896	Neurospora crassa	49.44	2.00e-128	450.00
IUUC-Nle-069369	Nomascus leucogenys	25.26	1.00e-31	129.00
IUUC-Opr-070975	Ochotona princeps	26.06	9.00e-28	116.00
IUUC-Ont-072528	Oreochromis niloticus	26.18	1.00e-23	102.00
IUUC-Oan-072955	Ornithorhynchus anatinus	24.79	1.00e-22	99.40
IUUC-Ocu-074561	Oryctolagus cuniculus	25.14	3.00e-28	118.00
IUUC-Oba-074982	Oryza barthii	26.53	9.00e-27	113.00
IUUC-Obr-076551	Oryza brachyantha	27.74	5.00e-20	89.40
IUUC-Ogl-077685	Oryza glaberrima	27.22	7.00e-28	116.00
IUUC-Ogu-078331	Oryza glumaepatula	26.94	9.00e-28	116.00
IUUC-Oin-079507	Oryza indica	26.74	3.00e-26	111.00
IUUC-Olo-080604	Oryza longistaminata	28.42	1.00e-24	105.00
IUUC-Ome-081816	Oryza meridionalis	26.26	4.00e-25	107.00
IUUC-Oni-082051	Oryza nivara	26.94	1.00e-27	115.00
IUUC-Opu-083372	Oryza punctata	26.94	6.00e-27	113.00
IUUC-Oru-084578	Oryza rufipogon	26.94	9.00e-28	116.00
IUUC-Osa-086177	Oryza sativa	26.94	9.00e-28	116.00
IUUC-Ola-087208	Oryzias latipes	26.67	2.00e-22	98.20
IUUC-Olu-087680	Ostreococcus lucimarinus	26.27	3.00e-22	98.20
IUUC-Oga-088104	Otolemur garnettii	25.59	7.00e-32	130.00
IUUC-Oar-090157	Ovis aries	25.20	3.00e-29	121.00
IUUC-Ptr-091615	Pan troglodytes	25.00	8.00e-32	130.00
IUUC-Pan-092212	Papio anubis	24.21	2.00e-29	122.00
IUUC-Psi-092950	Pelodiscus sinensis	23.86	3.00e-27	115.00
IUUC-Pma-094625	Petromyzon marinus	30.82	2.00e-13	67.80
IUUC-Pno-094824	Phaeosphaeria nodorum	57.82	1.00e-166	577.00
IUUC-Ppa-095414	Physcomitrella patens	24.20	1.00e-17	82.80
IUUC-Pfo-096922	Poecilia formosa	25.59	4.00e-28	117.00
IUUC-Pab-097591	Pongo abelii	25.26	2.00e-32	132.00
IUUC-Pop-099337	Populus trichocarpa	24.96	4.00e-28	117.00
IUUC-Pca-101025	Procavia capensis	25.06	1.00e-28	119.00
IUUC-Ppe-101256	Prunus persica	26.95	8.00e-17	80.10
IUUC-Pva-102453	Pteropus vampyrus	25.98	3.00e-30	125.00
IUUC-Pgr-103436	Puccinia graminis	30.31	1.00e-53	202.00
IUUC-Ptt-103899	Puccinia triticina	36.79	2.00e-40	158.00
IUUC-Pte-104258	Pyrenophora teres	55.91	1.00e-163	567.00
IUUC-Pyt-104625	Pyrenophora triticirepentis	55.91	2.00e-163	566.00
IUUC-Rno-104843	Rattus norvegicus	22.99	9.00e-23	100.00
IUUC-Sce-106189	Saccharomyces cerevisiae	34.37	8.00e-51	192.00
IUUC-Sha-106672	Sarcophilus harrisii	24.25	2.00e-33	135.00
IUUC-Smo-109660	Selaginella moellendorffii	27.04	2.00e-24	104.00
IUUC-Sit-109704	Setaria italica	27.22	4.00e-30	124.00
IUUC-Sly-111853	Solanum lycopersicum	25.69	5.00e-30	123.00
IUUC-Stu-112482	Solanum tuberosum	24.95	2.00e-29	121.00
IUUC-Sbi-114517	Sorghum bicolor	27.87	3.00e-24	104.00
IUUC-Sre-114960	Sporisorium reilianum	29.30	1.00e-25	109.00
IUUC-Ssc-115568	Sus scrofa	25.53	1.00e-30	126.00
IUUC-Tgu-117276	Taeniopygia guttata	22.63	1.00e-17	82.40
IUUC-Tru-117559	Takifugu rubripes	34.88	2.00e-07	45.80
IUUC-Tsy-119234	Tarsius syrichta	28.45	4.00e-09	54.70
IUUC-Tni-120358	Tetraodon nigroviridis	25.81	5.00e-26	110.00
IUUC-Tca-121273	Theobroma cacao	26.84	3.00e-23	101.00
IUUC-Tre-121932	Trichoderma reesei	48.02	1.00e-130	458.00
IUUC-Tvi-122567	Trichoderma virens	50.09	4.00e-138	483.00
IUUC-Tae-123506	Triticum aestivum	27.42	3.00e-23	100.00
IUUC-Tur-126533	Triticum urartu	31.13	1.00e-09	55.50
IUUC-Tme-126958	Tuber melanosporum	39.70	3.00e-82	296.00
IUUC-Tbe-127425	Tupaia belangeri	26.77	5.00e-31	127.00
IUUC-Ttr-129123	Tursiops truncatus	25.21	4.00e-27	114.00
IUUC-Uma-129495	Ustilago maydis	27.24	3.00e-34	138.00
IUUC-Vda-129981	Verticillium dahliae	48.87	1.00e-123	435.00
IUUC-Vpa-130437	Vicugna pacos	25.27	1.00e-29	122.00
IUUC-Vvi-131430	Vitis vinifera	24.72	3.00e-24	104.00
IUUC-Xtr-132670	Xenopus tropicalis	23.93	6.00e-27	113.00
IUUC-Xma-133375	Xiphophorus maculatus	26.33	2.00e-24	105.00
IUUC-Yli-134341	Yarrowia lipolytica	33.91	7.00e-74	269.00
IUUC-Zma-135413	Zea mays	26.61	2.00e-27	115.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence