iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073442

UUCD1 version

UUC-OrA-00859

Ensembl Protein ID

ENSOANP00000017977.2

UniProt Accession

F7G905; F7G905_ORNAN

Protein Name

Uncharacterized protein

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000011345.2	ENSOANT00000017980.2	ENSOANP00000017977.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-68	231.7	377	756

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.....kskkk..............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +  ++e +++ +++++++s+ +l++e++     ++ k+              a++p+
   Q: 377  GLINKGNWCYINATLQALVACPPMYHLMKF-VPLYTKE-QRPCTSTPMIDSFVRLMNEFTnmpvpSKAKQalgdkivrdirpgaAFEPT 463
           9***************************99.5555554.45799***************8877763333368899999999999***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsde............ 129
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+ +                  e+                 +            
   Q: 464  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLNlkkllspnnekfsvsngpEAP----------------Ianedeeqddqgd 536
           *9999999999966599********************44444666655666555544333................0333334444455 PP
   S: 130  ............aeekkkkknk...........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesft 195
                       +        k           ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +
   Q: 537  gsedewkqvgprN--------KtsitrqadfvqTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLV 613
           5555555555441........4445555557779**********9.688999999*******************99...********** PP
   S: 196  keeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLi 281
           ++e+++g    y++k k+++e +++++l+klP+vL+lhLkRf ++++++++ k+ k++++p  L++s+ + sp  k+k+   +++Y+L+
   Q: 614  ARESVQG----YTTKTKQEVEISRRVTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIDYPVDLEISKELLSPGVKSKNfkgHRTYRLF 697
           ******8....99999****************************9998886.****************99998777776777******* PP
   S: 282  avvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
           avv+H+G s+ +GHY+++v +   + Wl++dD+ V+++++ +v++ ++ +taY+l+Y+r
   Q: 698  AVVYHHGnSATGGHYTTDVFQIGLNgWLRIDDQAVKVINQYQVVKPSAeRTAYLLYYRR 756
           *********************87777*****************998778********98 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MPGSKVDCHL LGEEYQRIEF GVNEVIEPDA SVLNNTNYSI SSTLNPQAPE FILGCTPSPK 60
SHDDLRNESN FNSVDCQFPG PAVALDSNSN VEAENAENDG LSGGLGQKER KKKKKRPPGY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGATCAAAT GCTGTTTATT AAATTACTTT AAACACTTTT CCCCCTGCAG CTTCCTCCAT 60
ACAATGAACC AATTTTATGT GGCACTCAGT CCACAGGTGA ACTCCGTGAT GGTAAGTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	31.19	2.00e-47	182.00
IUUC-Aml-001584	Ailuropoda melanoleuca	79.20	0.00e+00	1128.00
IUUC-Atr-002927	Amborella trichopoda	35.13	4.00e-60	225.00
IUUC-Apl-003988	Anas platyrhynchos	85.15	0.00e+00	1189.00
IUUC-Aca-004461	Anolis carolinensis	93.11	3.00e-169	587.00
IUUC-Aly-006038	Arabidopsis lyrata	35.29	2.00e-55	209.00
IUUC-Ath-007328	Arabidopsis thaliana	35.04	4.00e-54	205.00
IUUC-Ago-007717	Ashbya gossypii	31.91	2.00e-46	180.00
IUUC-Acl-008188	Aspergillus clavatus	33.73	4.00e-65	242.00
IUUC-Afl-008456	Aspergillus flavus	37.62	4.00e-51	194.00
IUUC-Afu-009067	Aspergillus fumigatus	36.75	1.00e-67	250.00
IUUC-Ani-009483	Aspergillus nidulans	32.97	1.00e-63	237.00
IUUC-Ang-009639	Aspergillus niger	34.51	2.00e-61	230.00
IUUC-Aor-010040	Aspergillus oryzae	34.78	7.00e-64	238.00
IUUC-Ate-010310	Aspergillus terreus	34.03	2.00e-65	243.00
IUUC-Ame-011012	Astyanax mexicanus	75.92	1.00e-173	602.00
IUUC-Bgr-012311	Blumeria graminis	36.44	2.00e-49	190.00
IUUC-Bta-013299	Bos taurus	77.10	0.00e+00	1069.00
IUUC-Bci-013783	Botrytis cinerea	37.50	3.00e-62	233.00
IUUC-Bdi-015039	Brachypodium distachyon	33.50	3.00e-51	196.00
IUUC-Bol-015806	Brassica oleracea	36.32	1.00e-64	240.00
IUUC-Bra-017076	Brassica rapa	36.32	1.00e-64	239.00
IUUC-Cja-018715	Callithrix jacchus	78.80	0.00e+00	1119.00
IUUC-Cfa-020194	Canis familiaris	79.60	0.00e+00	1128.00
IUUC-Cpo-022272	Cavia porcellus	67.51	0.00e+00	917.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	33.67	2.00e-35	143.00
IUUC-Csa-023310	Chlorocebus sabaeus	79.73	0.00e+00	1140.00
IUUC-Cho-024966	Choloepus hoffmanni	75.70	0.00e+00	747.00
IUUC-Cin-025616	Ciona intestinalis	47.37	2.00e-107	382.00
IUUC-Csv-026043	Ciona savignyi	45.90	5.00e-101	360.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	34.31	3.00e-47	182.00
IUUC-Cne-026962	Cryptococcus neoformans	35.62	2.00e-51	197.00
IUUC-Cme-027113	Cyanidioschyzon merolae	29.74	5.00e-38	151.00
IUUC-Dre-028072	Danio rerio	79.44	0.00e+00	747.00
IUUC-Dno-029489	Dasypus novemcinctus	81.33	0.00e+00	1188.00
IUUC-Dor-031068	Dipodomys ordii	68.90	8.00e-136	477.00
IUUC-Dse-031553	Dothistroma septosporum	37.06	4.00e-58	219.00
IUUC-Dme-031759	Drosophila melanogaster	40.18	9.00e-85	308.00
IUUC-Ete-032549	Echinops telfairi	72.01	0.00e+00	799.00
IUUC-Eca-033380	Equus caballus	79.33	0.00e+00	1145.00
IUUC-Eeu-034818	Erinaceus europaeus	77.53	0.00e+00	1094.00
IUUC-Fca-035535	Felis catus	77.79	0.00e+00	1026.00
IUUC-Fal-036627	Ficedula albicollis	79.04	0.00e+00	1104.00
IUUC-Fox-037904	Fusarium oxysporum	36.81	1.00e-55	211.00
IUUC-Fso-038170	Fusarium solani	33.72	2.00e-55	210.00
IUUC-Gmo-039499	Gadus morhua	73.79	0.00e+00	682.00
IUUC-Ggr-040042	Gaeumannomyces graminis	36.72	1.00e-64	241.00
IUUC-Gga-040571	Gallus gallus	85.58	0.00e+00	1182.00
IUUC-Gac-041345	Gasterosteus aculeatus	78.45	0.00e+00	686.00
IUUC-Gma-044407	Glycine max	35.29	3.00e-60	225.00
IUUC-Ggo-044652	Gorilla gorilla	79.87	0.00e+00	1158.00
IUUC-Hsa-045864	Homo sapiens	79.73	0.00e+00	1157.00
IUUC-Hvu-047071	Hordeum vulgare	32.75	2.00e-54	205.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	82.91	0.00e+00	934.00
IUUC-Kpa-049132	Komagataella pastoris	31.17	3.00e-47	182.00
IUUC-Lch-050040	Latimeria chalumnae	73.32	0.00e+00	978.00
IUUC-Lpe-050772	Leersia perrieri	28.40	6.00e-17	81.60
IUUC-Loc-052449	Lepisosteus oculatus	74.12	0.00e+00	735.00
IUUC-Lma-053248	Leptosphaeria maculans	36.39	3.00e-61	229.00
IUUC-Laf-054121	Loxodonta africana	79.20	0.00e+00	1152.00
IUUC-Mcc-055514	Macaca mulatta	78.80	0.00e+00	1137.00
IUUC-Meu-056873	Macropus eugenii	78.61	0.00e+00	904.00
IUUC-Mor-057243	Magnaporthe oryzae	33.93	6.00e-60	225.00
IUUC-Mpo-057439	Magnaporthe poae	35.20	5.00e-62	232.00
IUUC-Mtr-058457	Medicago truncatula	33.50	1.00e-57	216.00
IUUC-Mla-058929	Melampsora laricipopulina	31.50	6.00e-58	218.00
IUUC-Mga-060157	Meleagris gallopavo	85.47	0.00e+00	1199.00
IUUC-Mvi-060442	Microbotryum violaceum	32.13	2.00e-55	210.00
IUUC-Mmr-061062	Microcebus murinus	79.20	0.00e+00	1155.00
IUUC-Mdo-062798	Monodelphis domestica	86.65	0.00e+00	1235.00
IUUC-Mmu-064050	Mus musculus	75.87	0.00e+00	1077.00
IUUC-Mac-065202	Musa acuminata	34.35	7.00e-55	207.00
IUUC-Mpu-066554	Mustela putorius furo	79.09	0.00e+00	1103.00
IUUC-Mlu-068003	Myotis lucifugus	78.67	0.00e+00	1123.00
IUUC-Nfi-068612	Neosartorya fischeri	35.65	9.00e-65	241.00
IUUC-Ncr-068878	Neurospora crassa	34.85	2.00e-52	200.00
IUUC-Nle-069661	Nomascus leucogenys	79.73	0.00e+00	1144.00
IUUC-Opr-070944	Ochotona princeps	75.43	9.00e-162	563.00
IUUC-Ont-071266	Oreochromis niloticus	60.62	0.00e+00	780.00
IUUC-Ocu-073788	Oryctolagus cuniculus	74.69	0.00e+00	1023.00
IUUC-Oba-075085	Oryza barthii	33.69	3.00e-37	147.00
IUUC-Obr-076663	Oryza brachyantha	32.32	3.00e-46	179.00
IUUC-Ogl-076937	Oryza glaberrima	29.93	5.00e-50	191.00
IUUC-Ogu-078909	Oryza glumaepatula	30.72	8.00e-48	184.00
IUUC-Oin-079617	Oryza indica	31.37	9.00e-50	191.00
IUUC-Olo-081043	Oryza longistaminata	26.24	2.00e-24	106.00
IUUC-Ome-081646	Oryza meridionalis	24.94	3.00e-23	103.00
IUUC-Oni-082914	Oryza nivara	30.72	6.00e-48	184.00
IUUC-Oru-084878	Oryza rufipogon	30.25	7.00e-48	184.00
IUUC-Osa-085822	Oryza sativa	31.18	3.00e-52	198.00
IUUC-Ola-086931	Oryzias latipes	58.59	0.00e+00	745.00
IUUC-Oga-088443	Otolemur garnettii	79.20	0.00e+00	1145.00
IUUC-Oar-089325	Ovis aries	76.00	0.00e+00	1005.00
IUUC-Ptr-091584	Pan troglodytes	76.93	0.00e+00	1067.00
IUUC-Pan-092551	Papio anubis	77.60	0.00e+00	1100.00
IUUC-Psi-093366	Pelodiscus sinensis	81.66	0.00e+00	783.00
IUUC-Pno-095136	Phaeosphaeria nodorum	36.10	3.00e-54	206.00
IUUC-Ppa-095574	Physcomitrella patens	36.14	5.00e-61	228.00
IUUC-Pfo-097462	Poecilia formosa	78.76	0.00e+00	716.00
IUUC-Pab-098547	Pongo abelii	79.87	0.00e+00	1145.00
IUUC-Pop-099529	Populus trichocarpa	37.08	1.00e-63	236.00
IUUC-Pca-101066	Procavia capensis	72.36	0.00e+00	1041.00
IUUC-Ppe-102110	Prunus persica	36.29	7.00e-61	227.00
IUUC-Pva-103015	Pteropus vampyrus	79.07	0.00e+00	1068.00
IUUC-Ptt-103998	Puccinia triticina	31.75	1.00e-53	203.00
IUUC-Pte-104417	Pyrenophora teres	33.58	7.00e-56	211.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	35.01	3.00e-56	213.00
IUUC-Rno-105533	Rattus norvegicus	76.89	0.00e+00	1098.00
IUUC-Sce-106160	Saccharomyces cerevisiae	28.06	2.00e-42	166.00
IUUC-Sha-106590	Sarcophilus harrisii	86.11	0.00e+00	1225.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	35.51	9.00e-59	220.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.59	4.00e-67	248.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	36.96	2.00e-61	230.00
IUUC-Smo-109645	Selaginella moellendorffii	34.64	5.00e-38	150.00
IUUC-Sit-110781	Setaria italica	32.48	2.00e-56	213.00
IUUC-Sly-111797	Solanum lycopersicum	33.67	4.00e-56	211.00
IUUC-Stu-112188	Solanum tuberosum	34.35	8.00e-57	214.00
IUUC-Sbi-114862	Sorghum bicolor	32.35	3.00e-45	175.00
IUUC-Sre-115162	Sporisorium reilianum	35.59	5.00e-69	255.00
IUUC-Ssc-115505	Sus scrofa	89.68	8.00e-162	561.00
IUUC-Tgu-116535	Taeniopygia guttata	79.97	0.00e+00	1120.00
IUUC-Tru-117542	Takifugu rubripes	78.92	0.00e+00	739.00
IUUC-Tni-120200	Tetraodon nigroviridis	58.93	0.00e+00	787.00
IUUC-Tca-121548	Theobroma cacao	34.92	8.00e-45	174.00
IUUC-Tre-122124	Trichoderma reesei	33.68	5.00e-61	228.00
IUUC-Tvi-122457	Trichoderma virens	34.76	2.00e-54	207.00
IUUC-Tae-125646	Triticum aestivum	33.92	5.00e-57	215.00
IUUC-Tme-127180	Tuber melanosporum	40.32	6.00e-72	264.00
IUUC-Tbe-127530	Tupaia belangeri	67.03	0.00e+00	889.00
IUUC-Ttr-128549	Tursiops truncatus	71.69	0.00e+00	996.00
IUUC-Uma-129381	Ustilago maydis	34.48	5.00e-67	248.00
IUUC-Vda-129889	Verticillium dahliae	34.05	5.00e-55	209.00
IUUC-Vpa-130100	Vicugna pacos	73.67	0.00e+00	1001.00
IUUC-Vvi-131366	Vitis vinifera	35.53	2.00e-64	239.00
IUUC-Xtr-132048	Xenopus tropicalis	74.31	0.00e+00	929.00
IUUC-Xma-133593	Xiphophorus maculatus	58.64	0.00e+00	768.00
IUUC-Yli-134338	Yarrowia lipolytica	30.37	4.00e-33	135.00
IUUC-Zma-135586	Zea mays	31.72	2.00e-50	192.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence