iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009316

Ensembl Protein ID

CADANIAP00009232

UniProt Accession

Q5BAC3; C8VPI6; Q5BAC3_EMENI

Genbank Protein ID

CBF86993.1; EAA63992.1

Protein Name

Ubiquitin-specific protease, putative (AFU_orthologue AFUA_1G07555)

Genbank Nucleotide ID

BN001307; AACD01000042

Gene Name

ANIA_02507; AN2507.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00009232	CADANIAT00009232	CADANIAP00009232

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-20	72.7	73	391

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 7    gNtCYmNSvLQcLsnipelrellle.......kkkeklneenp...................kepkgellkslqklfeelwkskkk....... 66
            N CY N++L +L+++p +r                      p                   ++++g+ll+++ +lf+   ++++        
   Q: 73   DNLCYRNAALLALLHTPAFRTWAMGthlrynpL--------YPhhptckgptipldevlspnENKSGCLLCNIYTLFTWYHSGNRDkdcyiyk 157
           599********************9944433331........22455666667888888888889999**********9885333333466666 PP
   S: 67   .............avsprellkalkkeaee..fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisd 144
                        + +  +l++  +k+      ++ +qqD+ E+l+ l+++l++ +++                l+                 
   Q: 158  qvegtsvtvkgfhNWAMDALWRRYRKTRDGnwATSGSQQDVFELLERLIKALHRLVQH----------------LP---AHPIAGPDMGQPMG 231
           666666655555566677777777777665434599******************9922................11...22233344466788 PP
   S: 145  lFqgqlksqikclecdnvs..sreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLk 235
           lF  ++++  +c++c +       +  +++ lp+p ++ t  +++qd+++   +++ +  +n ++c   +k  +a++k +l+  PevL++++ 
   Q: 232  LFVSRIQDLEQCKNCPRYRnlGAADYYMYVGLPLPPRT-TFVPKFQDMINWAWNQDIIS-DNFCECGDLEK--RAVRKRRLELAPEVLMFQIE 320
           99999999999****99884557788888899999999.5799*******999999998.78889998875..5788889999********** PP
   S: 236  RfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDsk 313
           R   +++        + +++ +e+++ + +  + ++   + kY+  av+ H+G sl  GHY++ v++  +g+W  +dD+k
   Q: 321  RTVQNQKSL------RAFKLEDEFEVLSSVLPEGQA---SIKYNVKAVIFHQGpSLTAGHYTVGVREiGTGRWAFLDDDK 391
           **5555555......555555555555444443333...79**************************44556******86 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MSVNQDPNGQ SGPGLDLAPV AFDAATPDLL AAIGAGTSFA PDTFPAVYPV APAPPLPQRK 60
QNISEGFANP RGDNLCYRNA ALLALLHTPA FRTWAMGTHL RYNPLYPHHP TCKGPTIPLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAAGAT ATTCTTTACT AAGACAGGTG TGAGGTATTT TGTGGCTAAT ATCAACAGAG 60
TGTAAACCAG GATCCCAACG GTCAATCTGG CCCTGGCCTC GACTTAGCTC CTGTTGCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

KEGG

ani:AN2507.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afu-009073	Aspergillus fumigatus	23.03	3.00e-09	54.70
IUUC-Ang-009871	Aspergillus niger	26.41	3.00e-13	68.60
IUUC-Ate-010392	Aspergillus terreus	23.44	2.00e-12	65.90
IUUC-Nfi-068335	Neosartorya fischeri	27.03	4.00e-21	94.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence