iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040423

Ensembl Protein ID

ENSGALP00000027018.5

UniProt Accession

F1P5H4; F1P5H4_CHICK

Genbank Protein ID

ENSGALP00000027018

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

AADN04000082

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000016766.6	ENSGALT00000027069.5	ENSGALP00000027018.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	5.20e-17	61.3	1022	1050

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++ +++q++
   Q: 1022 AFSQVDPEVFAALPAELQAELKDAYDQRQ 1050
           59*************************98 PP

Organism

Gallus gallus

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MRRGGWRKRA GEGDGWGGWG GYMSAKVKKL EDQFRSDSAI QHQRDGNSSS IFSGVAIYVN 60
GFTDPSADEL RRLMMLHGGQ YHVYYSRSKT THIIATNLPN AKIKELKGEK VVRPEWIVES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCGTGACG CGCTCGCAGG AAGGGCGGGG GGAGGAGGGG CCGCTGCCGG GGACACCGAG 60
AGGGGGAGGA GGGGGAAGGA AGGAAGGAAG GGAGAGCGGG GAGAGCGGGG AGAGCGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	30.80	2.00e-33	137.00
IUUC-Aml-001185	Ailuropoda melanoleuca	75.47	0.00e+00	1777.00
IUUC-Atr-002915	Amborella trichopoda	32.74	1.00e-84	308.00
IUUC-Apl-004054	Anas platyrhynchos	94.19	0.00e+00	2307.00
IUUC-Aca-004304	Anolis carolinensis	71.03	0.00e+00	1690.00
IUUC-Aly-005696	Arabidopsis lyrata	35.80	2.00e-86	313.00
IUUC-Ath-006893	Arabidopsis thaliana	36.78	1.00e-86	315.00
IUUC-Ago-007722	Ashbya gossypii	33.15	7.00e-38	152.00
IUUC-Acl-008347	Aspergillus clavatus	44.81	2.00e-78	287.00
IUUC-Afl-008444	Aspergillus flavus	36.45	2.00e-86	313.00
IUUC-Afu-008837	Aspergillus fumigatus	32.23	1.00e-88	321.00
IUUC-Ani-009188	Aspergillus nidulans	44.51	2.00e-79	290.00
IUUC-Ang-009866	Aspergillus niger	32.55	2.00e-94	340.00
IUUC-Aor-010107	Aspergillus oryzae	36.45	3.00e-86	313.00
IUUC-Ate-010359	Aspergillus terreus	33.38	1.00e-93	338.00
IUUC-Ame-010664	Astyanax mexicanus	53.59	0.00e+00	902.00
IUUC-Bgr-012244	Blumeria graminis	33.21	2.00e-73	270.00
IUUC-Bta-013405	Bos taurus	71.36	0.00e+00	1545.00
IUUC-Bci-013849	Botrytis cinerea	34.87	1.00e-82	301.00
IUUC-Bdi-014066	Brachypodium distachyon	37.04	2.00e-86	313.00
IUUC-Bol-015544	Brassica oleracea	37.43	8.00e-88	318.00
IUUC-Bra-017792	Brassica rapa	35.33	1.00e-84	308.00
IUUC-Cel-018148	Caenorhabditis elegans	34.99	2.00e-80	293.00
IUUC-Cja-019742	Callithrix jacchus	65.36	0.00e+00	1223.00
IUUC-Cfa-020112	Canis familiaris	76.26	0.00e+00	1797.00
IUUC-Cpo-022152	Cavia porcellus	72.73	0.00e+00	1756.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	45.29	6.00e-41	162.00
IUUC-Csa-023504	Chlorocebus sabaeus	75.95	0.00e+00	1796.00
IUUC-Cho-024780	Choloepus hoffmanni	67.73	1.00e-165	577.00
IUUC-Cin-025276	Ciona intestinalis	37.42	3.00e-115	409.00
IUUC-Csv-026283	Ciona savignyi	42.89	5.00e-114	404.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	28.86	3.00e-89	323.00
IUUC-Cne-027079	Cryptococcus neoformans	39.13	1.00e-66	248.00
IUUC-Cme-027346	Cyanidioschyzon merolae	27.90	1.00e-44	175.00
IUUC-Dre-028073	Danio rerio	50.30	0.00e+00	1080.00
IUUC-Dno-030038	Dasypus novemcinctus	73.88	0.00e+00	1755.00
IUUC-Dor-031100	Dipodomys ordii	73.42	0.00e+00	1277.00
IUUC-Dse-031310	Dothistroma septosporum	30.33	2.00e-86	314.00
IUUC-Dme-031991	Drosophila melanogaster	41.62	5.00e-107	382.00
IUUC-Ete-033082	Echinops telfairi	69.89	0.00e+00	1238.00
IUUC-Eca-033471	Equus caballus	75.79	0.00e+00	1796.00
IUUC-Eeu-034993	Erinaceus europaeus	73.62	0.00e+00	1207.00
IUUC-Fca-035367	Felis catus	77.64	0.00e+00	1773.00
IUUC-Fal-036973	Ficedula albicollis	90.64	0.00e+00	2101.00
IUUC-Fox-037677	Fusarium oxysporum	30.95	4.00e-86	313.00
IUUC-Fso-038252	Fusarium solani	32.79	6.00e-92	332.00
IUUC-Gmo-039669	Gadus morhua	46.84	0.00e+00	721.00
IUUC-Ggr-039988	Gaeumannomyces graminis	42.44	6.00e-76	279.00
IUUC-Gac-042134	Gasterosteus aculeatus	49.42	0.00e+00	1009.00
IUUC-Gma-042929	Glycine max	32.81	2.00e-90	327.00
IUUC-Ggo-044528	Gorilla gorilla	75.63	0.00e+00	1783.00
IUUC-Hsa-046259	Homo sapiens	75.63	0.00e+00	1762.00
IUUC-Hvu-047139	Hordeum vulgare	36.73	5.00e-60	224.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	75.24	0.00e+00	1789.00
IUUC-Kpa-049169	Komagataella pastoris	35.14	6.00e-59	222.00
IUUC-Lch-050471	Latimeria chalumnae	66.46	0.00e+00	1509.00
IUUC-Lpe-050800	Leersia perrieri	29.32	2.00e-90	327.00
IUUC-Loc-052320	Lepisosteus oculatus	46.85	0.00e+00	900.00
IUUC-Lma-053149	Leptosphaeria maculans	28.88	4.00e-87	316.00
IUUC-Laf-053810	Loxodonta africana	72.84	0.00e+00	1682.00
IUUC-Mcc-055574	Macaca mulatta	75.47	0.00e+00	1752.00
IUUC-Meu-055945	Macropus eugenii	60.69	0.00e+00	1003.00
IUUC-Mor-057195	Magnaporthe oryzae	30.78	2.00e-90	327.00
IUUC-Mpo-057488	Magnaporthe poae	43.20	2.00e-77	284.00
IUUC-Mtr-057955	Medicago truncatula	43.57	7.00e-78	285.00
IUUC-Mla-059027	Melampsora laricipopulina	39.94	4.00e-65	242.00
IUUC-Mga-060156	Meleagris gallopavo	98.33	0.00e+00	2410.00
IUUC-Mvi-060398	Microbotryum violaceum	34.62	4.00e-75	276.00
IUUC-Mmr-061113	Microcebus murinus	76.12	0.00e+00	1780.00
IUUC-Mdo-063001	Monodelphis domestica	77.54	0.00e+00	1830.00
IUUC-Mmu-063180	Mus musculus	72.87	0.00e+00	1691.00
IUUC-Mac-065551	Musa acuminata	38.30	3.00e-52	199.00
IUUC-Mpu-066525	Mustela putorius furo	75.47	0.00e+00	1764.00
IUUC-Mlu-067877	Myotis lucifugus	75.75	0.00e+00	1768.00
IUUC-Nfi-068418	Neosartorya fischeri	32.60	5.00e-90	326.00
IUUC-Ncr-068648	Neurospora crassa	32.41	5.00e-90	326.00
IUUC-Nle-069959	Nomascus leucogenys	76.10	0.00e+00	1766.00
IUUC-Opr-070522	Ochotona princeps	70.77	0.00e+00	975.00
IUUC-Ont-072293	Oreochromis niloticus	50.10	0.00e+00	822.00
IUUC-Oan-073519	Ornithorhynchus anatinus	75.10	0.00e+00	1789.00
IUUC-Ocu-074492	Oryctolagus cuniculus	73.58	0.00e+00	1642.00
IUUC-Oba-075567	Oryza barthii	33.28	1.00e-90	328.00
IUUC-Obr-076332	Oryza brachyantha	36.21	4.00e-86	313.00
IUUC-Ogl-077348	Oryza glaberrima	29.24	2.00e-91	330.00
IUUC-Ogu-078779	Oryza glumaepatula	33.12	4.00e-90	326.00
IUUC-Oin-079738	Oryza indica	27.84	6.00e-80	292.00
IUUC-Olo-080701	Oryza longistaminata	30.78	4.00e-79	289.00
IUUC-Ome-081708	Oryza meridionalis	33.44	1.00e-87	318.00
IUUC-Oni-082251	Oryza nivara	32.97	4.00e-88	319.00
IUUC-Opu-083528	Oryza punctata	32.58	6.00e-83	302.00
IUUC-Oru-084293	Oryza rufipogon	32.50	4.00e-85	309.00
IUUC-Osa-085549	Oryza sativa	29.24	4.00e-91	329.00
IUUC-Ola-086793	Oryzias latipes	48.63	0.00e+00	1043.00
IUUC-Olu-087786	Ostreococcus lucimarinus	29.01	1.00e-61	230.00
IUUC-Oga-089006	Otolemur garnettii	75.49	0.00e+00	1761.00
IUUC-Oar-089597	Ovis aries	71.32	0.00e+00	1671.00
IUUC-Ptr-091520	Pan troglodytes	75.63	0.00e+00	1760.00
IUUC-Pan-092333	Papio anubis	75.63	0.00e+00	1743.00
IUUC-Psi-094004	Pelodiscus sinensis	84.03	0.00e+00	2003.00
IUUC-Pma-094128	Petromyzon marinus	54.06	3.00e-95	342.00
IUUC-Pno-094849	Phaeosphaeria nodorum	29.36	3.00e-78	286.00
IUUC-Ppa-095714	Physcomitrella patens	28.10	4.00e-99	356.00
IUUC-Pfo-096569	Poecilia formosa	52.59	0.00e+00	814.00
IUUC-Pab-097960	Pongo abelii	75.63	0.00e+00	1760.00
IUUC-Pop-098921	Populus trichocarpa	32.95	3.00e-86	313.00
IUUC-Pca-100509	Procavia capensis	64.24	0.00e+00	887.00
IUUC-Ppe-101730	Prunus persica	33.15	1.00e-97	351.00
IUUC-Pva-102142	Pteropus vampyrus	73.06	0.00e+00	1712.00
IUUC-Pgr-103446	Puccinia graminis	30.65	2.00e-68	253.00
IUUC-Ptt-103849	Puccinia triticina	30.00	2.00e-72	268.00
IUUC-Pte-104128	Pyrenophora teres	31.17	1.00e-84	308.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	32.34	4.00e-83	302.00
IUUC-Rno-104871	Rattus norvegicus	71.19	0.00e+00	1690.00
IUUC-Sce-106236	Saccharomyces cerevisiae	31.23	6.00e-38	152.00
IUUC-Sha-106962	Sarcophilus harrisii	77.30	0.00e+00	1810.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	37.96	2.00e-54	207.00
IUUC-Spo-108170	Schizosaccharomyces pombe	33.95	1.00e-63	238.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	30.43	2.00e-88	321.00
IUUC-Smo-109554	Selaginella moellendorffii	37.45	4.00e-88	319.00
IUUC-Sit-110479	Setaria italica	37.30	1.00e-73	271.00
IUUC-Sly-111752	Solanum lycopersicum	34.78	2.00e-92	333.00
IUUC-Sar-113304	Sorex araneus	74.42	0.00e+00	1713.00
IUUC-Sbi-114196	Sorghum bicolor	37.50	2.00e-74	274.00
IUUC-Sre-115151	Sporisorium reilianum	31.96	1.00e-83	305.00
IUUC-Ssc-116104	Sus scrofa	75.06	0.00e+00	1751.00
IUUC-Tgu-117438	Taeniopygia guttata	91.40	0.00e+00	2197.00
IUUC-Tru-118553	Takifugu rubripes	48.81	0.00e+00	986.00
IUUC-Tsy-119056	Tarsius syrichta	72.18	0.00e+00	1630.00
IUUC-Tni-119933	Tetraodon nigroviridis	51.95	0.00e+00	630.00
IUUC-Tca-121376	Theobroma cacao	33.08	4.00e-90	326.00
IUUC-Tre-121972	Trichoderma reesei	41.26	3.00e-72	266.00
IUUC-Tvi-122342	Trichoderma virens	30.27	1.00e-77	285.00
IUUC-Tae-123898	Triticum aestivum	37.74	2.00e-81	297.00
IUUC-Tur-126735	Triticum urartu	32.33	1.00e-38	155.00
IUUC-Tme-126999	Tuber melanosporum	32.63	4.00e-81	296.00
IUUC-Tbe-127280	Tupaia belangeri	75.48	3.00e-117	416.00
IUUC-Ttr-129104	Tursiops truncatus	74.13	0.00e+00	1717.00
IUUC-Uma-129562	Ustilago maydis	30.42	5.00e-84	306.00
IUUC-Vda-129862	Verticillium dahliae	34.48	2.00e-80	294.00
IUUC-Vpa-130819	Vicugna pacos	70.53	0.00e+00	889.00
IUUC-Vvi-131111	Vitis vinifera	36.63	5.00e-87	316.00
IUUC-Xtr-132629	Xenopus tropicalis	62.34	0.00e+00	1406.00
IUUC-Xma-134065	Xiphophorus maculatus	53.38	0.00e+00	819.00
IUUC-Yli-134633	Yarrowia lipolytica	39.04	7.00e-56	212.00
IUUC-Zma-135176	Zea mays	33.23	2.00e-87	317.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence