iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062449

Ensembl Protein ID

ENSMODP00000007950.1

UniProt Accession

F7FD96; F7FD96_MONDO

Protein Name

Uncharacterized protein

Gene Name

TSG101

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000006410.2	ENSMODT00000008112.2	ENSMODP00000007950.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/UBC-like/UBD_UEV	1.20e-65	219.9	2	145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/UBC-like/UBD_UEV

   S: 1    AvsesslkkvpskykdkrltvrellnliesykslkpktasfvlnDgesreLlrltGtipvpergitynipiilwlletYPekPPfvsvk 89
           A+ es+lkk+ skyk+++ltvre++ +i+ yk+lkp+++s+v+nDg+sreL++ltGtipvp+rg++ynipi+lwll+tYP++PP+++vk
   Q: 2    AMPESQLKKMLSKYKYRDLTVRETVSVITLYKDLKPVLDSYVFNDGNSRELMSLTGTIPVPYRGNIYNIPICLWLLDTYPYNPPICFVK 90
           66799************************************************************************************ PP
   S: 90   ekidmntikssnehvdpnGkialpvLhkWknpasnlvelvqelivllskeppklsrp 146
           ++++m tik++ +hvd+nGki+lp+Lh+Wk+p+s+l+ l+q++iv++++epp++srp
   Q: 91   PTSSM-TIKTG-KHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRP 145
           *****.*****.*******************************************98 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAMPESQLKK MLSKYKYRDL TVRETVSVIT LYKDLKPVLD SYVFNDGNSR ELMSLTGTIP 60
VPYRGNIYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACATTTTCCG CAACTAGTAG TTTACTTATT GTAATCCCAG GTGTACTCAG TCTAACAGTC 60
CTAATATGAA GAGAATTATC AGCCTACAGG GTTCATGGTG TTTCAGACTT AACCCAGTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR017916--SB_dom
IPR016135--UBQ-conjugating_enzyme/RWD
IPR008883--UEV_N

PROSITE

PS51312--SB
PS51322--UEV

Pfam

PF05743--UEV
PF09454--Vps23_core

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0000813--C:ESCRT I complex
GO:0070062--C:extracellular exosome
GO:0005770--C:late endosome
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:0003714--F:transcription corepressor activity
GO:0046790--F:virion binding
GO:0007050--P:cell cycle arrest
GO:0006464--P:cellular protein modification process
GO:1990182--P:exosomal secretion
GO:0030216--P:keratinocyte differentiation
GO:0008285--P:negative regulation of cell proliferation
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1903543--P:positive regulation of exosomal secretion
GO:2000397--P:positive regulation of ubiquitin-dependent endocytosis
GO:1903774--P:positive regulation of viral budding via host ESCRT complex
GO:1902188--P:positive regulation of viral release from host cell
GO:0015031--P:protein transport
GO:0001558--P:regulation of cell growth
GO:1903551--P:regulation of extracellular exosome assembly
GO:0043405--P:regulation of MAP kinase activity
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0046755--P:viral budding

KEGG

mdo:100019704

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001072	Aegilops tauschii	27.62	3.00e-27	115.00
IUUC-Aml-002415	Ailuropoda melanoleuca	93.61	0.00e+00	711.00
IUUC-Atr-002875	Amborella trichopoda	31.34	2.00e-39	156.00
IUUC-Apl-003473	Anas platyrhynchos	87.76	0.00e+00	681.00
IUUC-Aca-004573	Anolis carolinensis	89.29	0.00e+00	663.00
IUUC-Aly-006164	Arabidopsis lyrata	42.16	2.00e-20	93.20
IUUC-Ath-006575	Arabidopsis thaliana	28.61	3.00e-29	122.00
IUUC-Ago-007755	Ashbya gossypii	25.00	6.00e-07	48.90
IUUC-Acl-008218	Aspergillus clavatus	37.98	2.00e-24	107.00
IUUC-Afl-008597	Aspergillus flavus	39.85	6.00e-26	112.00
IUUC-Afu-009017	Aspergillus fumigatus	37.21	1.00e-22	101.00
IUUC-Ani-009468	Aspergillus nidulans	37.88	2.00e-20	94.40
IUUC-Ang-009755	Aspergillus niger	35.71	7.00e-22	99.00
IUUC-Aor-010072	Aspergillus oryzae	38.35	6.00e-26	112.00
IUUC-Ate-010400	Aspergillus terreus	37.98	2.00e-24	107.00
IUUC-Ame-011620	Astyanax mexicanus	80.10	0.00e+00	634.00
IUUC-Bgr-012136	Blumeria graminis	34.31	3.00e-22	99.80
IUUC-Bta-012557	Bos taurus	94.12	0.00e+00	729.00
IUUC-Bci-013881	Botrytis cinerea	36.69	7.00e-25	108.00
IUUC-Bdi-014325	Brachypodium distachyon	34.91	2.00e-13	69.70
IUUC-Bol-015933	Brassica oleracea	42.37	2.00e-23	103.00
IUUC-Bra-017605	Brassica rapa	39.52	4.00e-25	108.00
IUUC-Cel-018697	Caenorhabditis elegans	45.83	3.00e-37	149.00
IUUC-Cja-018963	Callithrix jacchus	88.32	0.00e+00	698.00
IUUC-Cfa-020472	Canis familiaris	94.12	0.00e+00	712.00
IUUC-Cpo-022001	Cavia porcellus	94.88	0.00e+00	717.00
IUUC-Cre-022918	Chlamydomonas reinhardtii	28.61	1.00e-31	130.00
IUUC-Csa-023959	Chlorocebus sabaeus	94.12	0.00e+00	685.00
IUUC-Cho-024389	Choloepus hoffmanni	53.64	5.00e-36	145.00
IUUC-Cin-025688	Ciona intestinalis	45.04	2.00e-99	355.00
IUUC-Cne-026904	Cryptococcus neoformans	31.02	4.00e-17	83.20
IUUC-Cme-027280	Cyanidioschyzon merolae	39.09	2.00e-17	83.20
IUUC-Dre-027913	Danio rerio	80.36	5.00e-174	603.00
IUUC-Dno-029672	Dasypus novemcinctus	93.86	0.00e+00	717.00
IUUC-Dor-030175	Dipodomys ordii	92.00	3.00e-91	328.00
IUUC-Dse-031375	Dothistroma septosporum	28.89	9.00e-23	101.00
IUUC-Dme-031736	Drosophila melanogaster	47.26	3.00e-97	348.00
IUUC-Ete-032343	Echinops telfairi	89.77	0.00e+00	680.00
IUUC-Eca-033926	Equus caballus	94.37	0.00e+00	710.00
IUUC-Eeu-034940	Erinaceus europaeus	86.96	0.00e+00	694.00
IUUC-Fca-035491	Felis catus	93.35	0.00e+00	699.00
IUUC-Fal-037508	Ficedula albicollis	89.29	0.00e+00	675.00
IUUC-Fox-037937	Fusarium oxysporum	31.54	8.00e-20	91.70
IUUC-Fso-038091	Fusarium solani	35.29	1.00e-23	103.00
IUUC-Gmo-039427	Gadus morhua	77.52	3.00e-169	587.00
IUUC-Ggr-039724	Gaeumannomyces graminis	36.57	2.00e-23	104.00
IUUC-Gga-040998	Gallus gallus	89.54	0.00e+00	711.00
IUUC-Gac-041356	Gasterosteus aculeatus	79.54	0.00e+00	634.00
IUUC-Gma-043566	Glycine max	38.89	1.00e-24	107.00
IUUC-Ggo-044967	Gorilla gorilla	94.12	0.00e+00	685.00
IUUC-Hsa-046686	Homo sapiens	94.12	0.00e+00	685.00
IUUC-Hvu-047430	Hordeum vulgare	27.30	3.00e-27	116.00
IUUC-Itr-047929	Ictidomys tridecemlineatus	93.30	5.00e-108	383.00
IUUC-Kpa-049287	Komagataella pastoris	25.00	1.00e-28	120.00
IUUC-Lch-050597	Latimeria chalumnae	85.71	0.00e+00	697.00
IUUC-Lpe-051090	Leersia perrieri	38.02	7.00e-20	91.70
IUUC-Loc-052399	Lepisosteus oculatus	83.29	5.00e-176	610.00
IUUC-Lma-053249	Leptosphaeria maculans	28.95	7.00e-13	68.90
IUUC-Laf-053766	Loxodonta africana	94.63	0.00e+00	714.00
IUUC-Mcc-055641	Macaca mulatta	94.12	0.00e+00	685.00
IUUC-Meu-055919	Macropus eugenii	93.56	2.00e-173	600.00
IUUC-Mor-056970	Magnaporthe oryzae	37.69	1.00e-22	101.00
IUUC-Mpo-057345	Magnaporthe poae	36.15	2.00e-21	97.10
IUUC-Mtr-058436	Medicago truncatula	29.79	3.00e-34	139.00
IUUC-Mla-059037	Melampsora laricipopulina	37.24	4.00e-26	112.00
IUUC-Mga-059263	Meleagris gallopavo	89.35	0.00e+00	692.00
IUUC-Mvi-060463	Microbotryum violaceum	29.94	2.00e-17	84.30
IUUC-Mmr-060915	Microcebus murinus	94.12	0.00e+00	710.00
IUUC-Mmu-063151	Mus musculus	91.30	0.00e+00	693.00
IUUC-Mac-065020	Musa acuminata	36.29	1.00e-22	100.00
IUUC-Mpu-066621	Mustela putorius furo	93.61	0.00e+00	711.00
IUUC-Mlu-067336	Myotis lucifugus	94.12	0.00e+00	696.00
IUUC-Nfi-068530	Neosartorya fischeri	37.98	1.00e-22	101.00
IUUC-Ncr-068785	Neurospora crassa	35.29	5.00e-23	102.00
IUUC-Nle-069972	Nomascus leucogenys	94.12	0.00e+00	685.00
IUUC-Opr-071150	Ochotona princeps	84.11	7.00e-86	310.00
IUUC-Ont-071366	Oreochromis niloticus	78.55	0.00e+00	630.00
IUUC-Oan-073290	Ornithorhynchus anatinus	92.17	2.00e-103	368.00
IUUC-Ocu-074351	Oryctolagus cuniculus	94.12	0.00e+00	712.00
IUUC-Oba-075338	Oryza barthii	26.29	2.00e-11	62.80
IUUC-Obr-076135	Oryza brachyantha	26.83	2.00e-28	119.00
IUUC-Ogl-077182	Oryza glaberrima	36.28	1.00e-16	80.90
IUUC-Ogu-078281	Oryza glumaepatula	26.30	2.00e-20	93.20
IUUC-Oin-079068	Oryza indica	36.28	3.00e-16	79.70
IUUC-Olo-080460	Oryza longistaminata	28.26	2.00e-08	51.60
IUUC-Ome-081781	Oryza meridionalis	24.86	1.00e-17	84.30
IUUC-Oni-082517	Oryza nivara	25.55	7.00e-21	95.10
IUUC-Opu-084101	Oryza punctata	36.28	9.00e-17	81.30
IUUC-Oru-084556	Oryza rufipogon	36.84	1.00e-16	80.50
IUUC-Osa-086264	Oryza sativa	36.28	1.00e-16	80.90
IUUC-Ola-087252	Oryzias latipes	91.28	6.00e-68	249.00
IUUC-Olu-087610	Ostreococcus lucimarinus	27.17	5.00e-16	79.00
IUUC-Oga-088304	Otolemur garnettii	94.37	0.00e+00	710.00
IUUC-Oar-089734	Ovis aries	94.12	0.00e+00	729.00
IUUC-Ptr-091476	Pan troglodytes	94.12	0.00e+00	685.00
IUUC-Pan-092341	Papio anubis	94.12	0.00e+00	685.00
IUUC-Psi-093470	Pelodiscus sinensis	91.69	0.00e+00	664.00
IUUC-Pma-094143	Petromyzon marinus	64.09	7.00e-132	463.00
IUUC-Pno-095069	Phaeosphaeria nodorum	33.02	3.00e-13	70.10
IUUC-Ppa-095933	Physcomitrella patens	30.81	9.00e-39	154.00
IUUC-Pfo-096321	Poecilia formosa	81.70	3.00e-173	600.00
IUUC-Pab-098527	Pongo abelii	93.48	5.00e-175	606.00
IUUC-Pop-099323	Populus trichocarpa	27.65	4.00e-36	145.00
IUUC-Pca-101044	Procavia capensis	77.24	2.00e-155	541.00
IUUC-Ppe-101458	Prunus persica	41.67	2.00e-26	113.00
IUUC-Pva-103014	Pteropus vampyrus	85.17	2.00e-170	592.00
IUUC-Pgr-103615	Puccinia graminis	38.35	8.00e-21	95.10
IUUC-Ptt-103826	Puccinia triticina	41.18	1.00e-16	81.30
IUUC-Pte-104171	Pyrenophora teres	34.90	8.00e-21	95.10
IUUC-Pyt-104433	Pyrenophora triticirepentis	33.01	2.00e-10	60.50
IUUC-Rno-105957	Rattus norvegicus	90.28	0.00e+00	686.00
IUUC-Sce-106262	Saccharomyces cerevisiae	29.53	8.00e-11	61.20
IUUC-Sha-107607	Sarcophilus harrisii	98.85	3.00e-177	613.00
IUUC-Spo-108175	Schizosaccharomyces pombe	29.63	2.40e-02	33.50
IUUC-Ssl-108672	Sclerotinia sclerotiorum	36.03	4.00e-25	109.00
IUUC-Smo-108973	Selaginella moellendorffii	38.60	9.00e-20	90.90
IUUC-Sly-111373	Solanum lycopersicum	36.51	4.00e-23	102.00
IUUC-Stu-112844	Solanum tuberosum	36.51	1.00e-22	100.00
IUUC-Sar-113653	Sorex araneus	78.66	2.00e-170	592.00
IUUC-Sbi-114390	Sorghum bicolor	27.17	5.00e-29	122.00
IUUC-Sre-115200	Sporisorium reilianum	37.67	2.00e-23	103.00
IUUC-Ssc-115888	Sus scrofa	94.27	2.00e-110	391.00
IUUC-Tgu-117506	Taeniopygia guttata	88.07	0.00e+00	685.00
IUUC-Tru-118063	Takifugu rubripes	78.15	8.00e-170	589.00
IUUC-Tsy-118851	Tarsius syrichta	72.41	3.00e-140	491.00
IUUC-Tni-120010	Tetraodon nigroviridis	77.41	2.00e-167	581.00
IUUC-Tca-121182	Theobroma cacao	38.89	1.00e-21	97.10
IUUC-Tre-122040	Trichoderma reesei	35.38	2.00e-20	94.00
IUUC-Tvi-122660	Trichoderma virens	38.97	3.00e-24	106.00
IUUC-Tae-124561	Triticum aestivum	27.62	3.00e-27	115.00
IUUC-Tur-126651	Triticum urartu	37.19	5.00e-20	91.70
IUUC-Tme-127184	Tuber melanosporum	46.43	8.00e-25	108.00
IUUC-Tbe-127894	Tupaia belangeri	79.00	2.00e-86	312.00
IUUC-Ttr-128264	Tursiops truncatus	86.45	0.00e+00	687.00
IUUC-Uma-129407	Ustilago maydis	38.57	1.00e-24	108.00
IUUC-Vda-130002	Verticillium dahliae	35.64	8.00e-15	75.10
IUUC-Vpa-130156	Vicugna pacos	92.00	2.00e-93	335.00
IUUC-Vvi-131479	Vitis vinifera	40.35	1.00e-22	100.00
IUUC-Xtr-132332	Xenopus tropicalis	80.15	4.00e-62	229.00
IUUC-Xma-133186	Xiphophorus maculatus	81.96	6.00e-177	613.00
IUUC-Yli-134500	Yarrowia lipolytica	32.90	2.00e-12	66.60
IUUC-Zma-135391	Zea mays	36.13	2.00e-19	90.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence