iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060020

UUCD1 version

UUC-MeG-00841

Ensembl Protein ID

ENSMGAP00000002053.2

UniProt Accession

G1MU74; G1MU74_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000016773.1	ENSMGAT00000002726.2	ENSMGAP00000002053.2
ENSMGAG00000016773.1	ENSMGAT00000002722.2	ENSMGAP00000002049.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-101	339.6	239	569

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           tGl+NlgNtC+mNS+LQcLsn++elr+++l+ ++ ++ln++  + + ++l+++++kl++ lw +s + +vsp+e++++++++a++f gy
   Q: 239  TGLRNLGNTCFMNSILQCLSNTKELRDYCLQnQYLRDLNNN--SRMRTALMSEFAKLIQLLWtSSPNDSVSPSEFKTQIQRYAPRFVGY 325
           7******************************6666777655..78*****************999999********************* PP
   S: 88   eqqDaqEflaflldqleeelkk.....eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfld 171
           +qqDaqEfl+flld+l++e+++     ++n ++ +   +d  e+s++ +++ +++++s +sdlF gqlks+++c ec+  s+ ++pf+d
   Q: 326  NQQDAQEFLRFLLDGLHSEVNRvlvrpRANADTLDHLPDD--EKSRQMWRRYQEREDSRVSDLFVGQLKSSLTCSECGYCSTAFDPFWD 412
           ********************99666444444444443333..5666689**************************************** PP
   S: 172  lslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.L 259
           lslp+p+k    + +l dcL+ ftke+ l+g++k  c +ck++++++kk++++k+P++L+lhLkRf  se++ + +k+++ v+fpl+ L
   Q: 413  LSLPIPKKGYG-EVTLMDCLRLFTKEDVLDGDEKPTCCRCKARTRCTKKFSIQKFPKILVLHLKRF--SEARIRASKLSTFVNFPLKdL 498
           *******9976.779***************************************************..9999***************** PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           dl++f +++++    +  Y+L+av +HsG++ +GHY+ay+k+  + +W  f+Ds+Vt+++ + v +   s+aY+lfY+
   Q: 499  DLREFASQSCN----HAVYNLYAVSNHSGTTMGGHYTAYCKSpISSEWHSFNDSRVTPMSSSHVRS---SDAYLLFYE 569
           ********775....679************************55666*******************...********8 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MSQLSSTLKR YVDSSRYAEN TYSKMPSGYS SYTSYGSTYA YADRDKIGFK SSYLPSSRYH 60
HSRLSPTSGY DSGRLPLYPD SSIRLSPAYI RTQPGGGLSG GSCYSFTGTP SSPSGYVSTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCAGC TCTCCTCCAC ACTGAAACGG TACGTTGACT CGTCCCGCTA TGCCGAGAAC 60
ACCTACAGCA AGATGCCCAG CGGCTACAGC TCCTACACCT CCTACGGCTC CACCTATGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	61.80	0.00e+00	667.00
IUUC-Aca-005132	Anolis carolinensis	64.74	0.00e+00	723.00
IUUC-Afu-009001	Aspergillus fumigatus	33.61	7.00e-52	199.00
IUUC-Ang-009844	Aspergillus niger	33.61	3.00e-52	199.00
IUUC-Ate-010585	Aspergillus terreus	33.97	5.00e-51	196.00
IUUC-Ame-011102	Astyanax mexicanus	76.15	1.00e-149	522.00
IUUC-Bta-012529	Bos taurus	61.22	0.00e+00	631.00
IUUC-Bol-015281	Brassica oleracea	37.20	3.00e-49	189.00
IUUC-Bra-016678	Brassica rapa	37.50	2.00e-50	192.00
IUUC-Cel-018186	Caenorhabditis elegans	33.92	3.00e-51	196.00
IUUC-Cja-019016	Callithrix jacchus	58.69	1.00e-175	608.00
IUUC-Cfa-020714	Canis familiaris	61.88	0.00e+00	677.00
IUUC-Cpo-021727	Cavia porcellus	62.44	0.00e+00	655.00
IUUC-Csa-023071	Chlorocebus sabaeus	82.76	2.00e-170	591.00
IUUC-Cho-024836	Choloepus hoffmanni	51.81	6.00e-51	194.00
IUUC-Cin-025797	Ciona intestinalis	53.60	2.00e-102	365.00
IUUC-Csv-026132	Ciona savignyi	52.16	4.00e-105	374.00
IUUC-Dre-027872	Danio rerio	75.13	2.00e-167	581.00
IUUC-Dno-029329	Dasypus novemcinctus	60.38	0.00e+00	687.00
IUUC-Dor-030574	Dipodomys ordii	62.32	0.00e+00	654.00
IUUC-Dse-031463	Dothistroma septosporum	34.30	8.00e-43	169.00
IUUC-Dme-032208	Drosophila melanogaster	50.45	3.00e-88	319.00
IUUC-Ete-032725	Echinops telfairi	48.21	2.00e-77	283.00
IUUC-Eca-033361	Equus caballus	61.70	0.00e+00	659.00
IUUC-Eeu-035272	Erinaceus europaeus	84.15	4.00e-86	311.00
IUUC-Fca-036497	Felis catus	61.88	0.00e+00	667.00
IUUC-Fal-036766	Ficedula albicollis	80.41	0.00e+00	879.00
IUUC-Gmo-039129	Gadus morhua	63.74	1.00e-126	445.00
IUUC-Gga-040889	Gallus gallus	91.18	2.00e-172	598.00
IUUC-Gac-042475	Gasterosteus aculeatus	70.03	2.00e-139	488.00
IUUC-Ggo-044814	Gorilla gorilla	74.33	3.00e-152	530.00
IUUC-Hsa-045937	Homo sapiens	60.48	0.00e+00	635.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	61.77	0.00e+00	672.00
IUUC-Lch-050527	Latimeria chalumnae	64.69	8.00e-175	606.00
IUUC-Loc-052697	Lepisosteus oculatus	77.78	4.00e-165	574.00
IUUC-Lma-053021	Leptosphaeria maculans	35.37	3.00e-56	213.00
IUUC-Laf-054167	Loxodonta africana	61.58	0.00e+00	672.00
IUUC-Mcc-055584	Macaca mulatta	60.67	0.00e+00	648.00
IUUC-Meu-056542	Macropus eugenii	61.97	0.00e+00	651.00
IUUC-Mmr-060989	Microcebus murinus	61.35	0.00e+00	660.00
IUUC-Mdo-062761	Monodelphis domestica	62.52	0.00e+00	653.00
IUUC-Mmu-063710	Mus musculus	61.18	0.00e+00	658.00
IUUC-Mpu-066573	Mustela putorius furo	61.88	0.00e+00	666.00
IUUC-Mlu-067359	Myotis lucifugus	46.52	2.00e-79	289.00
IUUC-Nle-070013	Nomascus leucogenys	59.90	8.00e-176	609.00
IUUC-Opr-070907	Ochotona princeps	62.40	0.00e+00	649.00
IUUC-Ont-071944	Oreochromis niloticus	81.32	3.00e-169	587.00
IUUC-Oan-073105	Ornithorhynchus anatinus	76.49	2.00e-138	484.00
IUUC-Ocu-073941	Oryctolagus cuniculus	61.54	0.00e+00	657.00
IUUC-Ola-087412	Oryzias latipes	64.92	1.00e-156	545.00
IUUC-Oga-088973	Otolemur garnettii	61.22	0.00e+00	659.00
IUUC-Oar-089916	Ovis aries	62.09	0.00e+00	677.00
IUUC-Ptr-090998	Pan troglodytes	60.38	0.00e+00	639.00
IUUC-Pan-092686	Papio anubis	60.83	0.00e+00	650.00
IUUC-Psi-093284	Pelodiscus sinensis	75.54	4.00e-132	463.00
IUUC-Pma-094462	Petromyzon marinus	65.83	2.00e-79	287.00
IUUC-Pno-094986	Phaeosphaeria nodorum	32.94	3.00e-43	169.00
IUUC-Pfo-097352	Poecilia formosa	78.89	5.00e-174	603.00
IUUC-Pab-098688	Pongo abelii	55.47	7.00e-156	543.00
IUUC-Pca-100205	Procavia capensis	80.12	8.00e-168	583.00
IUUC-Pva-103188	Pteropus vampyrus	60.29	0.00e+00	646.00
IUUC-Pte-104348	Pyrenophora teres	32.75	1.00e-42	168.00
IUUC-Rno-105853	Rattus norvegicus	61.34	0.00e+00	677.00
IUUC-Sha-107237	Sarcophilus harrisii	62.36	0.00e+00	655.00
IUUC-Sar-113103	Sorex araneus	78.96	9.00e-159	551.00
IUUC-Ssc-115955	Sus scrofa	61.56	0.00e+00	647.00
IUUC-Tgu-116894	Taeniopygia guttata	80.82	0.00e+00	714.00
IUUC-Tru-117703	Takifugu rubripes	67.35	1.00e-131	462.00
IUUC-Tsy-118879	Tarsius syrichta	74.76	3.00e-177	613.00
IUUC-Tni-119866	Tetraodon nigroviridis	74.13	3.00e-157	547.00
IUUC-Tbe-127367	Tupaia belangeri	47.95	8.00e-84	304.00
IUUC-Ttr-128773	Tursiops truncatus	61.01	0.00e+00	645.00
IUUC-Vpa-130402	Vicugna pacos	84.62	2.00e-106	379.00
IUUC-Xtr-132658	Xenopus tropicalis	56.41	9.00e-167	579.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence