iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116894

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01045646

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000000390.1	ENSTGUT00000000409.1	ENSTGUP00000000403.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-101	339.8	98	428

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           tGl+NlgNtC+mNS+LQcLsn +elr+++l+ ++ ++ln++  + + ++l+++++kl++ lw +s +++vsp+e++++++++a++f gy
   Q: 98   TGLRNLGNTCFMNSILQCLSNSKELRDYCLQnQYLRDLNNN--SRMRTALMSEFAKLIQLLWtSSPNESVSPSEFKTQIQRYAPRFVGY 184
           7******************************6666777655..78*****************999999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeed...kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           +qqDaqEfl+flld+l++e+++    p+ ++ + d   + e+s++ +++ +++++s isdlF gqlks+++c ec+  s+ ++pf+dls
   Q: 185  NQQDAQEFLRFLLDGLHSEVNRVLVRPRASTDSLDhlpDDEKSRQMWRRYQEREDSRISDLFVGQLKSSLTCSECGYCSTAFDPFWDLS 273
           *********************9555555555444400034555569******************************************* PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldl 261
           lp+p+k    + +l dcL+ ftke+ l+g++k  c +ck++++++kk++++k+P++L+lhLkRf  se++ +++k+++ v+fpl+ Ldl
   Q: 274  LPIPKKGYG-EVTLMDCLRLFTKEDVLDGDEKPTCCRCKARTRCTKKFSIQKFPKILVLHLKRF--SEARIRSSKLTTFVNFPLKdLDL 359
           *****9976.779***************************************************..9999******************* PP
   S: 262  spfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           ++f +++++    +  Y+L+av +HsG++ +GHY+ay+k+   + W  f+Ds+Vt+++ + v +   s+aY+lfY+
   Q: 360  REFASQSCN----HAVYNLYAVSNHSGTTMGGHYTAYCKSPVSSeWHSFNDSRVTPMSSSHVRS---SDAYLLFYE 428
           ******775....679************************65555*******************...********8 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

LSRHKSISHS DLAREFSGLH TSDSAYLPAA GTLGTRGHLQ GLYQAAAHSD YVRGYLEAYG 60
RKSHPGSLSS SHLSPSQASL PPCSGPLPAS SKAVQGLTGL RNLGNTCFMN SILQCLSNSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGCCGCC ACAAATCCAT CAGCCACTCG GACCTGGCGC GGGAGTTCTC GGGGTTGCAC 60
ACCTCTGACA GCGCCTACCT GCCCGCGGCT GGCACGCTTG GCACCCGCGG CCACCTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	70.97	0.00e+00	632.00
IUUC-Aca-005132	Anolis carolinensis	74.68	0.00e+00	695.00
IUUC-Afu-009001	Aspergillus fumigatus	33.88	2.00e-51	197.00
IUUC-Ang-009844	Aspergillus niger	33.88	5.00e-52	199.00
IUUC-Ame-011102	Astyanax mexicanus	75.79	2.00e-148	518.00
IUUC-Bta-012529	Bos taurus	70.97	6.00e-176	610.00
IUUC-Bra-016678	Brassica rapa	37.50	2.00e-49	189.00
IUUC-Cja-019016	Callithrix jacchus	67.86	3.00e-163	568.00
IUUC-Cfa-020714	Canis familiaris	70.76	0.00e+00	630.00
IUUC-Cpo-021727	Cavia porcellus	69.98	1.00e-177	615.00
IUUC-Csa-023071	Chlorocebus sabaeus	82.71	2.00e-169	587.00
IUUC-Cin-025797	Ciona intestinalis	53.03	5.00e-102	363.00
IUUC-Csv-026132	Ciona savignyi	52.16	3.00e-104	372.00
IUUC-Dre-027872	Danio rerio	80.94	5.00e-166	576.00
IUUC-Dno-029329	Dasypus novemcinctus	70.97	0.00e+00	661.00
IUUC-Dor-030574	Dipodomys ordii	71.40	4.00e-178	617.00
IUUC-Dse-031463	Dothistroma septosporum	34.56	2.00e-43	171.00
IUUC-Dme-032208	Drosophila melanogaster	49.55	3.00e-86	312.00
IUUC-Ete-032725	Echinops telfairi	57.61	2.00e-74	273.00
IUUC-Eca-033361	Equus caballus	71.19	0.00e+00	630.00
IUUC-Eeu-035272	Erinaceus europaeus	84.70	9.00e-86	310.00
IUUC-Fca-036497	Felis catus	70.97	0.00e+00	632.00
IUUC-Fal-036766	Ficedula albicollis	89.44	0.00e+00	779.00
IUUC-Gmo-039129	Gadus morhua	66.67	5.00e-126	443.00
IUUC-Gga-040889	Gallus gallus	97.01	4.00e-167	580.00
IUUC-Gac-042475	Gasterosteus aculeatus	69.34	2.00e-139	488.00
IUUC-Ggo-044814	Gorilla gorilla	77.30	1.00e-149	521.00
IUUC-Hsa-045937	Homo sapiens	69.25	9.00e-175	606.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	70.44	0.00e+00	629.00
IUUC-Lch-050527	Latimeria chalumnae	66.74	1.00e-177	615.00
IUUC-Loc-052697	Lepisosteus oculatus	77.90	2.00e-164	572.00
IUUC-Lma-053021	Leptosphaeria maculans	35.64	9.00e-56	211.00
IUUC-Laf-054167	Loxodonta africana	70.32	0.00e+00	638.00
IUUC-Mcc-055584	Macaca mulatta	69.49	2.00e-178	618.00
IUUC-Meu-056542	Macropus eugenii	72.23	0.00e+00	632.00
IUUC-Mga-060020	Meleagris gallopavo	78.77	0.00e+00	696.00
IUUC-Mmr-060989	Microcebus murinus	70.55	1.00e-180	625.00
IUUC-Mdo-062761	Monodelphis domestica	71.18	0.00e+00	631.00
IUUC-Mmu-063710	Mus musculus	68.18	3.00e-178	617.00
IUUC-Mpu-066573	Mustela putorius furo	70.76	0.00e+00	629.00
IUUC-Nle-070013	Nomascus leucogenys	68.93	5.00e-164	570.00
IUUC-Opr-070907	Ochotona princeps	69.26	1.00e-177	615.00
IUUC-Ont-071944	Oreochromis niloticus	81.27	5.00e-168	582.00
IUUC-Oan-073105	Ornithorhynchus anatinus	76.78	3.00e-138	483.00
IUUC-Ocu-073941	Oryctolagus cuniculus	68.46	4.00e-177	613.00
IUUC-Ola-087412	Oryzias latipes	77.97	4.00e-154	537.00
IUUC-Oga-088973	Otolemur garnettii	70.34	3.00e-180	624.00
IUUC-Oar-089916	Ovis aries	70.76	0.00e+00	642.00
IUUC-Ptr-090998	Pan troglodytes	69.30	3.00e-177	614.00
IUUC-Pan-092686	Papio anubis	69.49	2.00e-178	618.00
IUUC-Psi-093284	Pelodiscus sinensis	76.15	5.00e-131	459.00
IUUC-Pma-094462	Petromyzon marinus	67.84	4.00e-79	286.00
IUUC-Pno-094986	Phaeosphaeria nodorum	32.94	9.00e-43	168.00
IUUC-Pfo-097352	Poecilia formosa	80.17	1.00e-172	598.00
IUUC-Pab-098688	Pongo abelii	62.05	3.00e-147	514.00
IUUC-Pca-100205	Procavia capensis	80.12	2.00e-166	578.00
IUUC-Pva-103188	Pteropus vampyrus	69.07	2.00e-176	611.00
IUUC-Pte-104348	Pyrenophora teres	33.33	7.00e-43	169.00
IUUC-Rno-105853	Rattus norvegicus	69.57	2.00e-180	625.00
IUUC-Sha-107237	Sarcophilus harrisii	70.75	0.00e+00	629.00
IUUC-Sar-113103	Sorex araneus	78.96	8.00e-159	552.00
IUUC-Ssc-115955	Sus scrofa	71.40	3.00e-175	608.00
IUUC-Tru-117703	Takifugu rubripes	66.47	2.00e-131	461.00
IUUC-Tsy-118879	Tarsius syrichta	72.37	3.00e-173	600.00
IUUC-Tni-119866	Tetraodon nigroviridis	78.37	4.00e-156	543.00
IUUC-Tbe-127367	Tupaia belangeri	56.21	2.00e-77	283.00
IUUC-Ttr-128773	Tursiops truncatus	68.80	2.00e-174	605.00
IUUC-Vpa-130402	Vicugna pacos	84.23	2.00e-105	375.00
IUUC-Xtr-132658	Xenopus tropicalis	62.81	4.00e-162	564.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence