iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093777

Ensembl Protein ID

ENSPSIP00000008382.1

UniProt Accession

K7FK22; K7FK22_PELSI

Genbank Protein ID

ENSPSIP00000008382

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01000982

Gene Name

PRPF19

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000007497.1	ENSPSIT00000008425.1	ENSPSIP00000008382.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-30	102.2	305	338
UBD/Beta-Prp	1.00e-53	182.5	146	376

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH++++t++af  ++ +l+ ++dD ++k+WDlr+
   Q: 305  GHSGPITSIAFseNGYYLAPAADDSSVKLWDLRK 338
           8**********86669999999*********986 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
             d++ ++tg++d+ ++v+d ++++ l++l+gh ++vt+v f+p++++  ++s D+ti++w++ + +cv+++++he+ v+ ls++++gd
   Q: 146  PSDTNKILTGGADKNVIVFDKSSEQILATLKGHAKKVTSVVFHPSQELVFSASPDATIRIWSVPSATCVQVVRAHENAVTGLSLHATGD 234
           568899*********************************************************************************** PP
   S: 108  klvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkel 195
           +l+s s+d++    d++tg +l + t++    + +c+++hpdg ++ +G+ D+++++Wdlk  + +  + g h ++++s++f++ng +l
   Q: 235  YLLSSSDDQYWAFSDIQTGRVLTKvTDETSGCALTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYL 322
           **********************997777777799************************************9.***************** PP
   S: 196  vsgsldgtvklwdlqtgecvrtlnghtd.nvksvrfspnderlvsgssDgsiri 248
           + +++d++vklwdl++ +  +tl+  ++  vks+ f++ +++l+ g+ D +i+i
   Q: 323  APAADDSSVKLWDLRKLKNFKTLQLDNNfEVKSLIFDQSGTYLALGGTDVQIYI 376
           ***************999999999866527*******************99987 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MLHSFTLRQQ LQTTRQELSH ALYQHDAACR VIARLTKEVT AAREALATLK PQAGLIVPQA 60
VPSSQPNITG AGEPMDLGEL VGMTPEIIQK LQDKATVLTT ERKKRGKTVP EELVKPEELS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCAAATGA GGTGCCAGAG CACCCTTGTG TATCGCCAGT CTCAAACCAT GTCTATGAGC 60
GAAGATTGAT TGAAAAGTAC ATTGCAGAAA ATGGGACTGA CCCAGTGAAC AACCAGCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR000772--Ricin_B_lectin
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50231--RICIN_B_LECTIN
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0005662--C:DNA replication factor A complex
GO:0005811--C:lipid particle
GO:0016020--C:membrane
GO:0016607--C:nuclear speck
GO:0000974--C:Prp19 complex
GO:0035861--C:site of double-strand break
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0034613--P:cellular protein localization
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0008610--P:lipid biosynthetic process
GO:0045665--P:negative regulation of neuron differentiation
GO:0048711--P:positive regulation of astrocyte differentiation
GO:0048026--P:positive regulation of mRNA splicing, via spliceosome
GO:0010498--P:proteasomal protein catabolic process
GO:0070534--P:protein K63-linked ubiquitination
GO:0072422--P:signal transduction involved in DNA damage checkpoint
GO:0000245--P:spliceosomal complex assembly
GO:0000244--P:spliceosomal tri-snRNP complex assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000488	Aegilops tauschii	40.69	1.00e-85	311.00
IUUC-Aml-001230	Ailuropoda melanoleuca	93.48	0.00e+00	769.00
IUUC-Atr-002594	Amborella trichopoda	44.04	2.00e-94	338.00
IUUC-Apl-003686	Anas platyrhynchos	91.75	0.00e+00	703.00
IUUC-Aca-005272	Anolis carolinensis	96.42	0.00e+00	819.00
IUUC-Aly-005586	Arabidopsis lyrata	43.81	4.00e-95	341.00
IUUC-Ath-007693	Arabidopsis thaliana	43.48	2.00e-92	332.00
IUUC-Acl-008335	Aspergillus clavatus	33.17	3.00e-43	169.00
IUUC-Afl-008527	Aspergillus flavus	34.62	4.00e-41	162.00
IUUC-Afu-008957	Aspergillus fumigatus	34.15	1.00e-46	180.00
IUUC-Ani-009280	Aspergillus nidulans	34.69	6.00e-35	141.00
IUUC-Ang-009746	Aspergillus niger	32.82	7.00e-36	144.00
IUUC-Aor-009905	Aspergillus oryzae	34.36	9.00e-45	174.00
IUUC-Ate-010412	Aspergillus terreus	34.10	7.00e-33	134.00
IUUC-Ame-011561	Astyanax mexicanus	85.81	1.00e-61	229.00
IUUC-Bgr-012283	Blumeria graminis	30.43	5.00e-31	128.00
IUUC-Bta-013242	Bos taurus	97.61	0.00e+00	825.00
IUUC-Bci-013901	Botrytis cinerea	31.03	5.00e-37	148.00
IUUC-Bdi-014277	Brachypodium distachyon	43.55	1.00e-96	347.00
IUUC-Bol-016207	Brassica oleracea	44.83	2.00e-92	333.00
IUUC-Bra-017902	Brassica rapa	43.81	1.00e-94	340.00
IUUC-Cel-018271	Caenorhabditis elegans	49.76	2.00e-121	428.00
IUUC-Cja-019879	Callithrix jacchus	97.14	0.00e+00	822.00
IUUC-Cfa-020175	Canis familiaris	97.37	0.00e+00	824.00
IUUC-Cpo-022379	Cavia porcellus	97.14	0.00e+00	822.00
IUUC-Cre-022993	Chlamydomonas reinhardtii	38.12	2.00e-72	266.00
IUUC-Csa-023500	Chlorocebus sabaeus	97.37	0.00e+00	824.00
IUUC-Cho-025065	Choloepus hoffmanni	80.53	1.00e-93	335.00
IUUC-Cin-025699	Ciona intestinalis	68.35	8.00e-140	489.00
IUUC-Csv-026128	Ciona savignyi	65.06	5.00e-161	560.00
IUUC-Cgl-026507	Colletotrichum gloeosporioides	29.88	2.00e-35	142.00
IUUC-Cne-026860	Cryptococcus neoformans	35.36	3.00e-67	249.00
IUUC-Dre-028187	Danio rerio	83.10	0.00e+00	692.00
IUUC-Dno-029453	Dasypus novemcinctus	97.14	0.00e+00	822.00
IUUC-Dor-030150	Dipodomys ordii	96.17	7.00e-125	440.00
IUUC-Dse-031220	Dothistroma septosporum	28.75	1.00e-29	124.00
IUUC-Dme-031906	Drosophila melanogaster	66.19	5.00e-162	563.00
IUUC-Ete-033035	Echinops telfairi	82.58	0.00e+00	671.00
IUUC-Eca-033478	Equus caballus	97.61	0.00e+00	825.00
IUUC-Eeu-034974	Erinaceus europaeus	97.87	0.00e+00	672.00
IUUC-Fca-036194	Felis catus	97.37	0.00e+00	824.00
IUUC-Fal-037417	Ficedula albicollis	96.90	0.00e+00	818.00
IUUC-Fox-037922	Fusarium oxysporum	31.88	6.00e-38	151.00
IUUC-Fso-038256	Fusarium solani	30.83	3.00e-38	152.00
IUUC-Gmo-038713	Gadus morhua	85.00	0.00e+00	709.00
IUUC-Ggr-039854	Gaeumannomyces graminis	29.52	5.00e-35	142.00
IUUC-Gga-041143	Gallus gallus	97.14	0.00e+00	820.00
IUUC-Gac-042129	Gasterosteus aculeatus	84.05	0.00e+00	728.00
IUUC-Gma-044273	Glycine max	45.56	5.00e-96	344.00
IUUC-Ggo-045262	Gorilla gorilla	97.37	0.00e+00	824.00
IUUC-Hsa-046036	Homo sapiens	97.37	0.00e+00	824.00
IUUC-Hvu-047442	Hordeum vulgare	43.70	5.00e-43	167.00
IUUC-Itr-048169	Ictidomys tridecemlineatus	96.66	0.00e+00	782.00
IUUC-Lch-050105	Latimeria chalumnae	89.02	0.00e+00	766.00
IUUC-Lpe-050976	Leersia perrieri	44.24	6.00e-94	337.00
IUUC-Loc-052042	Lepisosteus oculatus	71.96	8.00e-169	586.00
IUUC-Lma-053143	Leptosphaeria maculans	31.66	7.00e-37	149.00
IUUC-Laf-053451	Loxodonta africana	96.90	0.00e+00	822.00
IUUC-Mcc-055786	Macaca mulatta	97.37	0.00e+00	824.00
IUUC-Meu-056161	Macropus eugenii	97.93	1.00e-140	492.00
IUUC-Mor-057215	Magnaporthe oryzae	30.90	3.00e-30	125.00
IUUC-Mpo-057419	Magnaporthe poae	28.38	1.00e-32	134.00
IUUC-Mtr-057756	Medicago truncatula	44.60	7.00e-94	337.00
IUUC-Mla-059085	Melampsora laricipopulina	37.50	9.00e-70	257.00
IUUC-Mga-060158	Meleagris gallopavo	92.84	0.00e+00	772.00
IUUC-Mvi-060441	Microbotryum violaceum	35.32	6.00e-56	211.00
IUUC-Mmr-061085	Microcebus murinus	97.37	0.00e+00	824.00
IUUC-Mdo-061804	Monodelphis domestica	97.85	0.00e+00	827.00
IUUC-Mmu-063608	Mus musculus	97.14	0.00e+00	821.00
IUUC-Mac-064972	Musa acuminata	44.16	6.00e-92	330.00
IUUC-Mpu-065700	Mustela putorius furo	97.37	0.00e+00	824.00
IUUC-Mlu-068223	Myotis lucifugus	97.14	0.00e+00	821.00
IUUC-Nfi-068504	Neosartorya fischeri	33.41	7.00e-46	177.00
IUUC-Ncr-068729	Neurospora crassa	32.99	3.00e-35	142.00
IUUC-Nle-069754	Nomascus leucogenys	97.37	0.00e+00	824.00
IUUC-Opr-070621	Ochotona princeps	92.36	0.00e+00	773.00
IUUC-Ont-071377	Oreochromis niloticus	83.81	0.00e+00	702.00
IUUC-Oan-073498	Ornithorhynchus anatinus	93.96	2.00e-97	348.00
IUUC-Ocu-074182	Oryctolagus cuniculus	97.37	0.00e+00	824.00
IUUC-Oba-075509	Oryza barthii	43.84	2.00e-96	346.00
IUUC-Obr-076480	Oryza brachyantha	44.52	1.00e-96	347.00
IUUC-Ogl-077052	Oryza glaberrima	43.84	2.00e-96	345.00
IUUC-Ogu-078919	Oryza glumaepatula	43.84	2.00e-96	345.00
IUUC-Oin-079357	Oryza indica	43.22	1.00e-90	326.00
IUUC-Olo-080376	Oryza longistaminata	44.16	7.00e-97	347.00
IUUC-Ome-081973	Oryza meridionalis	43.84	2.00e-96	346.00
IUUC-Oni-082849	Oryza nivara	44.06	5.00e-97	347.00
IUUC-Opu-083243	Oryza punctata	43.61	6.00e-96	344.00
IUUC-Oru-084613	Oryza rufipogon	43.94	1.00e-96	346.00
IUUC-Osa-085407	Oryza sativa	43.81	5.00e-96	344.00
IUUC-Ola-086566	Oryzias latipes	83.06	0.00e+00	692.00
IUUC-Olu-087757	Ostreococcus lucimarinus	38.76	8.00e-73	267.00
IUUC-Oga-089010	Otolemur garnettii	92.69	0.00e+00	781.00
IUUC-Oar-089638	Ovis aries	97.61	0.00e+00	825.00
IUUC-Ptr-091141	Pan troglodytes	97.37	0.00e+00	824.00
IUUC-Pan-092662	Papio anubis	97.37	0.00e+00	824.00
IUUC-Pno-095115	Phaeosphaeria nodorum	32.06	4.00e-37	148.00
IUUC-Ppa-095841	Physcomitrella patens	43.22	1.00e-92	333.00
IUUC-Pfo-096390	Poecilia formosa	83.57	0.00e+00	705.00
IUUC-Pab-098250	Pongo abelii	95.25	0.00e+00	758.00
IUUC-Pop-099854	Populus trichocarpa	45.08	2.00e-95	342.00
IUUC-Pca-100553	Procavia capensis	96.66	0.00e+00	815.00
IUUC-Ppe-101383	Prunus persica	42.79	4.00e-88	318.00
IUUC-Pva-102189	Pteropus vampyrus	97.37	0.00e+00	824.00
IUUC-Pgr-103304	Puccinia graminis	35.37	1.00e-64	240.00
IUUC-Ptt-103984	Puccinia triticina	36.28	9.00e-70	257.00
IUUC-Pte-104385	Pyrenophora teres	30.18	2.00e-42	166.00
IUUC-Pyt-104697	Pyrenophora triticirepentis	30.69	3.00e-43	169.00
IUUC-Rno-105581	Rattus norvegicus	97.14	0.00e+00	822.00
IUUC-Sha-107071	Sarcophilus harrisii	97.37	0.00e+00	823.00
IUUC-Smo-109648	Selaginella moellendorffii	43.88	1.00e-93	337.00
IUUC-Sit-109873	Setaria italica	43.78	5.00e-94	338.00
IUUC-Sly-111673	Solanum lycopersicum	45.06	2.00e-88	319.00
IUUC-Stu-112125	Solanum tuberosum	44.83	1.00e-87	317.00
IUUC-Sbi-114696	Sorghum bicolor	42.22	2.00e-83	302.00
IUUC-Sre-115134	Sporisorium reilianum	28.18	4.00e-47	182.00
IUUC-Ssc-116260	Sus scrofa	97.37	0.00e+00	824.00
IUUC-Tgu-116533	Taeniopygia guttata	96.90	0.00e+00	818.00
IUUC-Tru-117800	Takifugu rubripes	82.86	0.00e+00	725.00
IUUC-Tsy-118980	Tarsius syrichta	97.33	0.00e+00	810.00
IUUC-Tni-120334	Tetraodon nigroviridis	79.59	5.00e-172	597.00
IUUC-Tca-121807	Theobroma cacao	44.04	2.00e-95	342.00
IUUC-Tre-121920	Trichoderma reesei	29.67	2.00e-37	149.00
IUUC-Tvi-122294	Trichoderma virens	30.43	3.00e-38	152.00
IUUC-Tae-125713	Triticum aestivum	44.01	1.00e-97	350.00
IUUC-Tur-126664	Triticum urartu	39.09	1.00e-89	323.00
IUUC-Tme-127026	Tuber melanosporum	31.22	2.00e-39	157.00
IUUC-Tbe-127582	Tupaia belangeri	97.57	0.00e+00	669.00
IUUC-Ttr-128313	Tursiops truncatus	97.14	0.00e+00	815.00
IUUC-Uma-129626	Ustilago maydis	30.46	2.00e-49	189.00
IUUC-Vda-129699	Verticillium dahliae	33.16	6.00e-41	161.00
IUUC-Vpa-130593	Vicugna pacos	96.54	0.00e+00	727.00
IUUC-Vvi-131668	Vitis vinifera	44.16	6.00e-95	341.00
IUUC-Xtr-132186	Xenopus tropicalis	85.59	7.00e-177	612.00
IUUC-Xma-133212	Xiphophorus maculatus	83.33	0.00e+00	699.00
IUUC-Zma-135662	Zea mays	44.93	5.00e-97	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence