iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026084

UUCD1 version

UUC-CiS-00443

Ensembl Protein ID

ENSCSAVP00000010967.1

UniProt Accession

H2Z055; H2Z055_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000006424.1	ENSCSAVT00000011098.1	ENSCSAVP00000010967.1
ENSCSAVG00000006424.1	ENSCSAVT00000011099.1	ENSCSAVP00000010968.1
ENSCSAVG00000006424.1	ENSCSAVT00000011100.1	ENSCSAVP00000010969.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.00e-195	648.8	456	940

Active Site

Position(s)	Description	Evidence
645	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.............gsitvvDmdtvevsnlnrqFLfraedvgksKAe 75
           YD+Qi+++G + q+kl+s+++++vGag++GcEllKn+ ++G+             gsi+v+Dmdt+e+snlnrqFLfr +dv+k K+e
   Q: 456  YDGQIAVFGKDFQKKLSSQHWFVVGAGAIGCELLKNFSMIGLgckvgdpkeeeneGSIYVTDMDTIEKSNLNRQFLFRTHDVQKLKSE 543
           **************************************************************************************** PP
   S: 76   vaaealkelnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecy 160
           +aa a+k++np  +++ h++++ +++e+++   Ff+++d+V++aldn++ar +++r+c+++ +pl+esgtlG++G+++v+i++ te+y
   Q: 544  CAASAVKKMNPLARIVCHSNRVGPETEKVYtdnFFENLDGVANALDNVQARIYMDRRCVYYGKPLLESGTLGTKGNIQVVIPHSTESY 631
           **************************************************************************************** PP
   S: 161  scsddppqktiPfctlketpnaaehtiewa.......vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieia 241
           s+s+dpp+k+iP+ctlk++pna+eht++           +n++l ++a++ e+ ++l  +e+  ++++v s+l+++++ +f ++++ a
   Q: 632  SSSQDPPEKSIPICTLKNFPNAIEHTLQFEglfrnsaDTANQYL-TDAKFYERISRLPGSEPIFTLEAVYSALVKNRPADFGDCVKFA 718
           ****************************9899999988888888.78889999999******************************** PP
   S: 242  vkafakttinsikqllksfecdivtkskspfwv....................................................... 274
           +  f++ ++n+i+qll++f+ d+v++s++ fw+                                                       
   Q: 719  RFRFQELYHNNIRQLLHNFPADQVNSSGALFWSgpkrcphpldfdpensthfdyvvsaanlhatmfgiptssdpttikkllgaftvpe 806
           ************************************************************************9999999999986663 PP
   S: 275  .sfcsnaealqvpekvekdeevvkasap.lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddli 358
            +  +   ++ + +  + ++   +++++ +  l++ + + ++ kg  +   +fekddd   ++d++ aa+nlrae+++i p +d+++ 
   Q: 807  fK-TKSGVKIATTDAEANSMNSGSMDDDrFNDLKKLIPSPDSFKGFRMVPADFEKDDDTnfHMDFIVAASNLRAENYEIAP-ADRHKS 892
           21.1122233333444444444444444799999***********************************************.****** PP
   S: 359  keiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           k iag+iipaiatt+a v+Gl+++E++K+v+g  k e +kn f+++a+
   Q: 893  KLIAGKIIPAIATTTALVAGLVSLELYKIVQGnkKLESYKNGFVNLAL 940
           ********************************9999*******99875 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

PSNSPPAKQR KTNHNSQAHI SNTSNSSGIK TMVDFLNQEQ VQNGNTTQDQ AIDESLYSRQ 60
LYVLGHDAMK RMGAANILIS GMKGLGIEVA KNVILGGVKA VTLHDEENAK VDHLSSQYFV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAAGCAATT CACCACCAGC AAAACAACGC AAAACGAACC ACAATTCTCA GGCACACATT 60
TCCAACACTT CAAATTCATC TGGTATCAAA ACCATGGTAG GTTTTTTGGT TACATTGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	43.05	0.00e+00	828.00
IUUC-Aml-001311	Ailuropoda melanoleuca	59.96	0.00e+00	1305.00
IUUC-Atr-002684	Amborella trichopoda	44.17	0.00e+00	839.00
IUUC-Apl-004158	Anas platyrhynchos	40.63	0.00e+00	698.00
IUUC-Aca-004620	Anolis carolinensis	61.10	0.00e+00	1299.00
IUUC-Aly-005515	Arabidopsis lyrata	42.50	0.00e+00	857.00
IUUC-Ath-006891	Arabidopsis thaliana	42.56	0.00e+00	848.00
IUUC-Ago-007873	Ashbya gossypii	50.00	0.00e+00	956.00
IUUC-Acl-008181	Aspergillus clavatus	53.66	0.00e+00	1030.00
IUUC-Afl-008455	Aspergillus flavus	53.85	0.00e+00	1001.00
IUUC-Afu-009065	Aspergillus fumigatus	53.56	0.00e+00	1041.00
IUUC-Ani-009371	Aspergillus nidulans	52.93	0.00e+00	1011.00
IUUC-Ang-009737	Aspergillus niger	53.37	0.00e+00	1018.00
IUUC-Aor-010007	Aspergillus oryzae	53.85	0.00e+00	1001.00
IUUC-Ate-010466	Aspergillus terreus	52.52	0.00e+00	1043.00
IUUC-Ame-010933	Astyanax mexicanus	61.97	0.00e+00	1269.00
IUUC-Bgr-012281	Blumeria graminis	51.15	0.00e+00	1025.00
IUUC-Bta-012767	Bos taurus	60.50	0.00e+00	1314.00
IUUC-Bci-013721	Botrytis cinerea	53.57	0.00e+00	993.00
IUUC-Bdi-014335	Brachypodium distachyon	42.86	0.00e+00	825.00
IUUC-Bol-015665	Brassica oleracea	42.90	0.00e+00	849.00
IUUC-Bra-017707	Brassica rapa	42.53	0.00e+00	847.00
IUUC-Cel-018260	Caenorhabditis elegans	46.45	0.00e+00	877.00
IUUC-Cja-019152	Callithrix jacchus	60.54	0.00e+00	1312.00
IUUC-Cfa-020622	Canis familiaris	59.01	0.00e+00	1241.00
IUUC-Cpo-022526	Cavia porcellus	60.35	0.00e+00	1295.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	43.73	0.00e+00	790.00
IUUC-Csa-023780	Chlorocebus sabaeus	60.50	0.00e+00	1313.00
IUUC-Cho-024682	Choloepus hoffmanni	34.24	2.00e-98	352.00
IUUC-Cin-025790	Ciona intestinalis	82.73	0.00e+00	1790.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	52.66	0.00e+00	1072.00
IUUC-Cne-026960	Cryptococcus neoformans	54.00	0.00e+00	1041.00
IUUC-Cme-027290	Cyanidioschyzon merolae	42.35	0.00e+00	784.00
IUUC-Dre-028149	Danio rerio	61.69	0.00e+00	1297.00
IUUC-Dno-028884	Dasypus novemcinctus	60.41	0.00e+00	1310.00
IUUC-Dor-030229	Dipodomys ordii	58.18	0.00e+00	1238.00
IUUC-Dse-031524	Dothistroma septosporum	50.09	0.00e+00	1023.00
IUUC-Dme-032045	Drosophila melanogaster	57.82	0.00e+00	1198.00
IUUC-Ete-032544	Echinops telfairi	62.62	2.00e-149	521.00
IUUC-Eca-033330	Equus caballus	60.41	0.00e+00	1315.00
IUUC-Eeu-034717	Erinaceus europaeus	38.22	7.00e-137	479.00
IUUC-Fca-036255	Felis catus	60.78	0.00e+00	1306.00
IUUC-Fal-037445	Ficedula albicollis	40.66	0.00e+00	731.00
IUUC-Fox-038007	Fusarium oxysporum	51.84	8.00e-155	538.00
IUUC-Fso-038339	Fusarium solani	52.66	0.00e+00	999.00
IUUC-Gmo-039338	Gadus morhua	59.55	0.00e+00	1229.00
IUUC-Ggr-039823	Gaeumannomyces graminis	50.28	0.00e+00	1032.00
IUUC-Gga-040747	Gallus gallus	40.72	0.00e+00	698.00
IUUC-Gac-041773	Gasterosteus aculeatus	59.58	0.00e+00	1221.00
IUUC-Gma-042755	Glycine max	44.10	0.00e+00	857.00
IUUC-Ggo-045336	Gorilla gorilla	60.41	0.00e+00	1298.00
IUUC-Hsa-045982	Homo sapiens	60.32	0.00e+00	1293.00
IUUC-Hvu-047418	Hordeum vulgare	42.51	0.00e+00	813.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	60.69	0.00e+00	1313.00
IUUC-Kpa-049112	Komagataella pastoris	49.04	0.00e+00	942.00
IUUC-Lch-050371	Latimeria chalumnae	61.22	0.00e+00	1295.00
IUUC-Lpe-051299	Leersia perrieri	41.94	0.00e+00	838.00
IUUC-Loc-052936	Lepisosteus oculatus	61.60	0.00e+00	1301.00
IUUC-Lma-053315	Leptosphaeria maculans	51.18	0.00e+00	1050.00
IUUC-Laf-053948	Loxodonta africana	59.67	0.00e+00	1273.00
IUUC-Mcc-055843	Macaca mulatta	60.69	0.00e+00	1316.00
IUUC-Meu-056258	Macropus eugenii	60.32	0.00e+00	1301.00
IUUC-Mor-057269	Magnaporthe oryzae	50.85	0.00e+00	1022.00
IUUC-Mpo-057435	Magnaporthe poae	50.42	0.00e+00	996.00
IUUC-Mtr-058572	Medicago truncatula	43.46	0.00e+00	813.00
IUUC-Mla-059176	Melampsora laricipopulina	52.72	0.00e+00	1023.00
IUUC-Mga-059721	Meleagris gallopavo	40.33	0.00e+00	681.00
IUUC-Mvi-060437	Microbotryum violaceum	50.97	0.00e+00	1012.00
IUUC-Mmr-061405	Microcebus murinus	59.33	0.00e+00	1269.00
IUUC-Mdo-062032	Monodelphis domestica	59.21	0.00e+00	1261.00
IUUC-Mmu-063280	Mus musculus	60.54	0.00e+00	1308.00
IUUC-Mac-065505	Musa acuminata	43.00	0.00e+00	832.00
IUUC-Mpu-066409	Mustela putorius furo	60.50	0.00e+00	1315.00
IUUC-Mlu-067217	Myotis lucifugus	60.17	0.00e+00	1291.00
IUUC-Nfi-068407	Neosartorya fischeri	53.66	0.00e+00	1025.00
IUUC-Ncr-068698	Neurospora crassa	53.16	0.00e+00	1069.00
IUUC-Nle-070072	Nomascus leucogenys	57.29	0.00e+00	1203.00
IUUC-Opr-070715	Ochotona princeps	37.63	0.00e+00	639.00
IUUC-Ont-071671	Oreochromis niloticus	60.81	0.00e+00	1263.00
IUUC-Oan-073268	Ornithorhynchus anatinus	39.88	0.00e+00	636.00
IUUC-Ocu-074544	Oryctolagus cuniculus	60.87	0.00e+00	1313.00
IUUC-Oba-075120	Oryza barthii	42.06	0.00e+00	804.00
IUUC-Obr-076244	Oryza brachyantha	42.84	0.00e+00	818.00
IUUC-Ogl-077887	Oryza glaberrima	41.96	0.00e+00	804.00
IUUC-Ogu-078305	Oryza glumaepatula	43.02	0.00e+00	828.00
IUUC-Oin-080154	Oryza indica	42.92	0.00e+00	827.00
IUUC-Olo-081089	Oryza longistaminata	43.02	0.00e+00	829.00
IUUC-Ome-081942	Oryza meridionalis	41.77	0.00e+00	803.00
IUUC-Oni-082365	Oryza nivara	42.06	0.00e+00	805.00
IUUC-Opu-083301	Oryza punctata	42.15	0.00e+00	809.00
IUUC-Oru-084469	Oryza rufipogon	43.02	0.00e+00	831.00
IUUC-Osa-085949	Oryza sativa	42.16	0.00e+00	813.00
IUUC-Ola-087002	Oryzias latipes	62.23	0.00e+00	1284.00
IUUC-Olu-087687	Ostreococcus lucimarinus	41.69	0.00e+00	735.00
IUUC-Oga-088594	Otolemur garnettii	60.13	0.00e+00	1295.00
IUUC-Oar-090068	Ovis aries	60.45	0.00e+00	1317.00
IUUC-Ptr-090609	Pan troglodytes	40.00	0.00e+00	693.00
IUUC-Pan-092114	Papio anubis	60.59	0.00e+00	1316.00
IUUC-Psi-093489	Pelodiscus sinensis	39.81	0.00e+00	702.00
IUUC-Pma-094214	Petromyzon marinus	51.70	1.00e-41	160.00
IUUC-Pno-095154	Phaeosphaeria nodorum	49.82	0.00e+00	1046.00
IUUC-Ppa-095227	Physcomitrella patens	43.95	0.00e+00	832.00
IUUC-Pfo-097184	Poecilia formosa	60.53	0.00e+00	1266.00
IUUC-Pab-097861	Pongo abelii	60.13	0.00e+00	1281.00
IUUC-Pop-098934	Populus trichocarpa	43.78	0.00e+00	857.00
IUUC-Pca-100347	Procavia capensis	59.78	0.00e+00	1070.00
IUUC-Ppe-102012	Prunus persica	42.53	0.00e+00	832.00
IUUC-Pva-102584	Pteropus vampyrus	60.50	0.00e+00	1333.00
IUUC-Pgr-103336	Puccinia graminis	51.08	0.00e+00	971.00
IUUC-Ptt-103939	Puccinia triticina	51.78	0.00e+00	982.00
IUUC-Pte-104200	Pyrenophora teres	51.48	0.00e+00	1047.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	50.14	0.00e+00	1035.00
IUUC-Rno-105462	Rattus norvegicus	62.18	0.00e+00	1300.00
IUUC-Sce-106245	Saccharomyces cerevisiae	48.55	0.00e+00	981.00
IUUC-Sha-107142	Sarcophilus harrisii	60.72	0.00e+00	1314.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	51.50	0.00e+00	1048.00
IUUC-Spo-108034	Schizosaccharomyces pombe	52.02	0.00e+00	1046.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	53.23	0.00e+00	1008.00
IUUC-Smo-109211	Selaginella moellendorffii	44.69	0.00e+00	844.00
IUUC-Sit-110281	Setaria italica	42.19	0.00e+00	827.00
IUUC-Sly-110914	Solanum lycopersicum	44.05	0.00e+00	861.00
IUUC-Stu-112109	Solanum tuberosum	43.76	0.00e+00	862.00
IUUC-Sar-113737	Sorex araneus	60.13	0.00e+00	1304.00
IUUC-Sbi-114089	Sorghum bicolor	42.61	0.00e+00	829.00
IUUC-Sre-115148	Sporisorium reilianum	52.87	0.00e+00	1019.00
IUUC-Ssc-115777	Sus scrofa	60.41	0.00e+00	1310.00
IUUC-Tgu-116565	Taeniopygia guttata	40.06	0.00e+00	694.00
IUUC-Tru-118742	Takifugu rubripes	60.43	0.00e+00	1221.00
IUUC-Tsy-119436	Tarsius syrichta	35.58	1.00e-164	572.00
IUUC-Tni-120401	Tetraodon nigroviridis	61.06	0.00e+00	1231.00
IUUC-Tca-121672	Theobroma cacao	43.47	0.00e+00	838.00
IUUC-Tre-122009	Trichoderma reesei	51.75	0.00e+00	994.00
IUUC-Tvi-122259	Trichoderma virens	51.43	0.00e+00	986.00
IUUC-Tae-125676	Triticum aestivum	42.72	0.00e+00	827.00
IUUC-Tur-126330	Triticum urartu	42.95	0.00e+00	827.00
IUUC-Tme-127055	Tuber melanosporum	49.72	0.00e+00	937.00
IUUC-Tbe-127487	Tupaia belangeri	54.91	2.00e-170	591.00
IUUC-Ttr-128331	Tursiops truncatus	60.22	0.00e+00	1295.00
IUUC-Uma-129387	Ustilago maydis	52.78	0.00e+00	1020.00
IUUC-Vda-129977	Verticillium dahliae	50.85	0.00e+00	956.00
IUUC-Vpa-130716	Vicugna pacos	38.73	0.00e+00	665.00
IUUC-Vvi-130857	Vitis vinifera	44.11	0.00e+00	857.00
IUUC-Xtr-132026	Xenopus tropicalis	51.35	0.00e+00	954.00
IUUC-Xma-133805	Xiphophorus maculatus	60.34	0.00e+00	1247.00
IUUC-Yli-134547	Yarrowia lipolytica	49.46	0.00e+00	1004.00
IUUC-Zma-135052	Zea mays	42.98	0.00e+00	833.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence