iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062119

UUCD1 version

UUC-MoD-00281

Ensembl Protein ID

ENSMODP00000036879.1

UniProt Accession

F6UPA9; F6UPA9_MONDO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000025096.1	ENSMODT00000038474.1	ENSMODP00000036879.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-37	126.1	422	460
UBD/Beta-Prp	2.00e-93	313.0	247	494

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH  ++++++f ++  ++++Gs+D+t+kvWDlr+ +++ 
   Q: 422  GHLKEIYGINFsPNgYHIATGSGDNTCKVWDLRQRRCVY 460
           7999********77799*****************99985 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk........ilvtgseDrtikvwdlstgkcvht 89
           ++ +i+   fsp+++llat++++g  k+w+v + +ll++l gh+  v a+ f+p++          l++++ D+ +k+w+l++ ++v  
   Q: 247  DDRPISYCNFSPNSKLLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTvsldkkdvNLASCAADGSVKLWSLESDEPVAD 335
           67899999*********************************************9988888889999*********************** PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++gh+ +v  + ++psg +l ++  dr  r+wdle ++++   ++gh+  v  +++h+dg+l  +G+lD + r+Wdl+tg+++  l+g 
   Q: 336  IEGHSVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEIL-HQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG- 422
           *****************************************.********************************************99. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriW 249
           h + +y ++f++ng ++++gs d+t k+wdl++ +cv+t  +h++ v+ v+f   ++++l++g+ D++ +iW
   Q: 423  HLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEpIHGNFLLTGAYDNTAKIW 494
           *****************************************************88***************** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

QKTMGGKWRL LTPTSDMASS RASATATKTP TRTPEDTASP VVKKPHIYYG SLEEKEKERL 60
ARGESGLLGK EGIKAGIEAG NINITSGEVF EIEEHISERQ AEVLAEFERR KRARQINVST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAAAACGA TGGGGGGGAA ATGGAGACTA TTAGTAGCGA ATCCTTCACA GGAAACGCAG 60
TTAGAAAAGT ACCTTCCCAG TTCCTCCTCC CTCTCACCTA CCTACAACAG GCTTGGCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR014906--PRP4-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08799--PRP4
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00500--SFM
SM00320--WD40

Gene Ontology

GO:0046540--C:U4/U6 x U5 tri-snRNP complex
GO:0030621--F:U4 snRNA binding
GO:0017070--F:U6 snRNA binding
GO:0000398--P:mRNA splicing, via spliceosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002828	Amborella trichopoda	43.98	4.00e-105	375.00
IUUC-Ago-007893	Ashbya gossypii	33.11	1.00e-56	213.00
IUUC-Acl-008236	Aspergillus clavatus	38.65	8.00e-92	330.00
IUUC-Ang-009662	Aspergillus niger	42.07	1.00e-98	353.00
IUUC-Cel-018632	Caenorhabditis elegans	43.84	2.00e-108	386.00
IUUC-Cre-022716	Chlamydomonas reinhardtii	47.47	4.00e-85	308.00
IUUC-Cin-025106	Ciona intestinalis	59.72	9.00e-178	616.00
IUUC-Csv-026087	Ciona savignyi	57.65	1.00e-176	612.00
IUUC-Dre-028723	Danio rerio	79.21	0.00e+00	786.00
IUUC-Dme-031783	Drosophila melanogaster	56.46	4.00e-138	484.00
IUUC-Mpo-057375	Magnaporthe poae	40.00	2.00e-53	202.00
IUUC-Mga-059855	Meleagris gallopavo	85.85	0.00e+00	933.00
IUUC-Mvi-060372	Microbotryum violaceum	42.49	4.00e-95	342.00
IUUC-Mmu-063351	Mus musculus	96.05	0.00e+00	985.00
IUUC-Olu-087580	Ostreococcus lucimarinus	35.47	1.00e-64	240.00
IUUC-Pab-097805	Pongo abelii	85.13	0.00e+00	855.00
IUUC-Pva-102529	Pteropus vampyrus	91.20	0.00e+00	952.00
IUUC-Sha-107334	Sarcophilus harrisii	99.41	0.00e+00	1008.00
IUUC-Sja-107794	Schizosaccharomyces japonicus	35.25	6.00e-72	265.00
IUUC-Sar-113266	Sorex araneus	83.40	0.00e+00	806.00
IUUC-Tsy-119157	Tarsius syrichta	96.92	0.00e+00	766.00
IUUC-Tae-125651	Triticum aestivum	43.64	6.00e-102	364.00
IUUC-Tme-126951	Tuber melanosporum	40.84	1.00e-102	367.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence