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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-106080
UUCD1 version UUC-RaN-00584
Ensembl Protein ID ENSRNOP00000005242.4
UniProt Accession Q5XIL0; RN167_RAT
Genbank Protein ID AAH83670.1
Protein Name E3 ubiquitin-protein ligase RNF167; RING finger protein 167; RING-type E3 ubiquitin transferase RNF167
Genbank Nucleotide ID BC083670
Gene Name Rnf167
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000003879.5 ENSRNOT00000005242.4 ENSRNOP00000005242.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 3.30e-09 37.5 230 272
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl++++dg  +++lpC H++h  C+  w     +++++ +CP+C+
   Q: 230  CAICLDEYEDGdkLRILPCAHAYHSRCVDPW-----LTQTRKTCPICK 272
           ********66666******************.....8**********7 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
 May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
Protein Sequence
(Fasta)
MHPAAFPLPV VVATVLWGAA PIRGLIRATS EHNASMDFAD LPALFGATLS DEGLQGFLVE 60
AHPENACSPI APPPSAPVNG SVFIALLRRF DCNFDLKVLN AQKAGYGAAV VHNVNSNELL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-106080|E3,RING|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAGGGGGTA AGAGGCTGGT GAGCATTCTC GCGATACTTG AACGTATCGC GGCGGCCAGA 60
AGAAGGAGAG GTTTGTAAAC AGGTAGCTCC AAGATCTCAG GGACTAAGGG AAAAAAATTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-106080|E3,RING|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF02225--PA
PF13639--zf-RING_2
SMART

SM00184--RING
SM00744--RINGv
Gene Ontology

GO:0005737--C:cytoplasm
GO:0012505--C:endomembrane system
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045786--P:negative regulation of cell cycle
GO:0000209--P:protein polyubiquitination
KEGG rno:360554
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001413 Ailuropoda melanoleuca 87.43 1.00e-132 466.00
IUUC-Ath-007212 Arabidopsis thaliana 31.86 1.00e-32 133.00
IUUC-Acl-008256 Aspergillus clavatus 60.42 6.00e-14 71.60
IUUC-Afl-008548 Aspergillus flavus 62.22 1.00e-13 70.50
IUUC-Afu-008977 Aspergillus fumigatus 62.22 3.00e-13 70.10
IUUC-Ang-009734 Aspergillus niger 62.22 6.00e-14 72.00
IUUC-Aor-010134 Aspergillus oryzae 62.22 1.00e-13 70.90
IUUC-Ate-010329 Aspergillus terreus 62.22 2.00e-13 70.10
IUUC-Bgr-012220 Blumeria graminis 55.56 2.00e-12 67.00
IUUC-Bta-012651 Bos taurus 96.86 1.00e-124 439.00
IUUC-Bci-013726 Botrytis cinerea 55.56 1.00e-12 67.80
IUUC-Cja-018953 Callithrix jacchus 94.53 1.00e-145 508.00
IUUC-Cfa-020540 Canis familiaris 72.05 3.00e-95 341.00
IUUC-Cpo-022372 Cavia porcellus 91.87 3.00e-169 587.00
IUUC-Cre-022631 Chlamydomonas reinhardtii 28.01 6.00e-23 101.00
IUUC-Csa-023070 Chlorocebus sabaeus 94.86 9.00e-158 549.00
IUUC-Cgl-026762 Colletotrichum gloeosporioides 60.00 1.00e-13 70.90
IUUC-Cne-026954 Cryptococcus neoformans 46.88 2.00e-13 70.90
IUUC-Dre-028786 Danio rerio 56.99 4.00e-81 295.00
IUUC-Dno-028877 Dasypus novemcinctus 90.96 2.00e-165 574.00
IUUC-Dor-030128 Dipodomys ordii 82.83 6.00e-151 526.00
IUUC-Ete-033067 Echinops telfairi 75.88 9.00e-106 376.00
IUUC-Eca-033699 Equus caballus 90.96 2.00e-156 544.00
IUUC-Eeu-034819 Erinaceus europaeus 90.03 1.00e-147 515.00
IUUC-Fca-036168 Felis catus 92.75 2.00e-145 508.00
IUUC-Fox-037990 Fusarium oxysporum 60.00 3.00e-13 70.10
IUUC-Fso-038278 Fusarium solani 60.00 5.00e-13 68.90
IUUC-Ggr-039870 Gaeumannomyces graminis 55.56 1.00e-12 67.80
IUUC-Gac-041339 Gasterosteus aculeatus 55.94 3.00e-78 285.00
IUUC-Gma-043776 Glycine max 32.32 4.00e-29 122.00
IUUC-Ggo-045113 Gorilla gorilla 94.52 2.00e-159 554.00
IUUC-Hsa-046476 Homo sapiens 92.58 4.00e-158 550.00
IUUC-Itr-047953 Ictidomys tridecemlineatus 92.47 7.00e-169 586.00
IUUC-Lch-050034 Latimeria chalumnae 62.60 4.00e-96 344.00
IUUC-Loc-051914 Lepisosteus oculatus 66.12 2.00e-85 309.00
IUUC-Lma-053199 Leptosphaeria maculans 58.33 6.00e-14 72.00
IUUC-Laf-053687 Loxodonta africana 92.88 8.00e-151 526.00
IUUC-Mcc-055879 Macaca mulatta 92.60 8.00e-159 553.00
IUUC-Meu-056408 Macropus eugenii 78.62 2.00e-114 405.00
IUUC-Mor-057236 Magnaporthe oryzae 60.00 2.00e-13 70.50
IUUC-Mpo-057321 Magnaporthe poae 55.56 2.00e-12 67.40
IUUC-Mmr-060656 Microcebus murinus 93.37 7.00e-169 586.00
IUUC-Mdo-062795 Monodelphis domestica 88.09 3.00e-135 474.00
IUUC-Mmu-063722 Mus musculus 95.78 3.00e-170 590.00
IUUC-Mpu-066094 Mustela putorius furo 87.34 1.00e-140 492.00
IUUC-Mlu-067350 Myotis lucifugus 89.46 1.00e-151 528.00
IUUC-Nfi-068514 Neosartorya fischeri 62.22 2.00e-13 70.50
IUUC-Ncr-068771 Neurospora crassa 54.00 2.00e-13 70.10
IUUC-Nle-069971 Nomascus leucogenys 95.16 2.00e-157 548.00
IUUC-Opr-070716 Ochotona princeps 94.17 4.00e-109 387.00
IUUC-Oan-072710 Ornithorhynchus anatinus 72.00 1.00e-68 252.00
IUUC-Ocu-074157 Oryctolagus cuniculus 94.86 1.00e-157 549.00
IUUC-Oin-080138 Oryza indica 32.58 1.00e-27 117.00
IUUC-Oni-082422 Oryza nivara 32.58 1.00e-27 117.00
IUUC-Opu-083162 Oryza punctata 32.78 2.00e-30 126.00
IUUC-Oga-089169 Otolemur garnettii 94.28 3.00e-171 594.00
IUUC-Oar-089216 Ovis aries 95.31 1.00e-153 535.00
IUUC-Ptr-091493 Pan troglodytes 94.52 2.00e-159 554.00
IUUC-Pan-092215 Papio anubis 94.53 3.00e-157 547.00
IUUC-Psi-093038 Pelodiscus sinensis 61.39 2.00e-104 372.00
IUUC-Pno-094907 Phaeosphaeria nodorum 62.22 5.00e-14 72.40
IUUC-Pfo-097514 Poecilia formosa 58.46 2.00e-79 289.00
IUUC-Pab-097739 Pongo abelii 88.32 2.00e-153 535.00
IUUC-Pca-100609 Procavia capensis 92.17 4.00e-155 540.00
IUUC-Pva-102834 Pteropus vampyrus 90.06 9.00e-165 572.00
IUUC-Pgr-103420 Puccinia graminis 44.44 7.00e-12 66.60
IUUC-Pte-104147 Pyrenophora teres 60.00 2.00e-13 70.50
IUUC-Pyt-104748 Pyrenophora triticirepentis 62.22 1.00e-13 71.20
IUUC-Sha-106787 Sarcophilus harrisii 87.00 1.00e-131 462.00
IUUC-Sar-113580 Sorex araneus 78.01 5.00e-122 430.00
IUUC-Ssc-115900 Sus scrofa 90.66 2.00e-168 584.00
IUUC-Tru-118584 Takifugu rubripes 53.38 2.00e-86 311.00
IUUC-Tsy-119134 Tarsius syrichta 89.27 7.00e-93 333.00
IUUC-Tni-120357 Tetraodon nigroviridis 58.94 2.00e-86 311.00
IUUC-Tre-121885 Trichoderma reesei 57.78 1.00e-12 67.80
IUUC-Tvi-122633 Trichoderma virens 57.78 1.00e-12 67.80
IUUC-Tae-123096 Triticum aestivum 33.71 7.00e-31 128.00
IUUC-Tme-127069 Tuber melanosporum 57.78 1.00e-12 67.40
IUUC-Tbe-127812 Tupaia belangeri 91.34 8.00e-126 442.00
IUUC-Ttr-128409 Tursiops truncatus 89.89 1.00e-127 448.00
IUUC-Vvi-131036 Vitis vinifera 31.98 3.00e-31 129.00
IUUC-Xma-133568 Xiphophorus maculatus 55.02 9.00e-75 273.00
Created Date 25-Jun-2017

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