iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118618

UUCD1 version

UUC-TaR-01048

Ensembl Protein ID

ENSTRUP00000031008.1

UniProt Accession

H2U247; H2U247_TAKRU

Protein Name

Uncharacterized protein

Gene Name

ube2kb; LOC101072344

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000012250.1	ENSTRUT00000031126.1	ENSTRUP00000031008.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.60e-45	154.8	8	146
UBD/UBC-like/UBD_UBC	2.10e-71	239.6	8	149
UBD/Alpha-Helix/UBA	9.20e-10	39.6	162	199

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp...egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsi 85
           R+k+e+ke+ k++    ++i++++v + ++te++ +i Gp+dtpYegg+++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+i
   Q: 8    RIKREFKEVIKSEEtikNQIKVELVGD-NFTELRGEIAGPPDTPYEGGKYHLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDI 95
           889999998655544459*********.9***************************************************99******* PP
   S: 86   lkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           lk  ++W +a+++++vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 96   LK--DQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 146
           *9..**********************************************986 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeea...qisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpnins.ngsicldil 85
           rik+e+k++ ++ee+   qi+++lv+d+++elr++iagppd+pyegg+++l+ik+p++ypf+ppkv+fitki+hpni+s +g+icldil
   Q: 8    RIKREFKEVIKSEETiknQIKVELVGDNFTELRGEIAGPPDTPYEGGKYHLEIKIPETYPFNPPKVRFITKIWHPNISSvTGAICLDIL 96
           8*************9999*********************************************************************** PP
   S: 86   rsqwsaaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           ++qw+aa+tl++vllsl++lla+aepddp++a++a++yk+++e++k++ar+w+
   Q: 97   KDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWS 149
           ****************************************************5 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLld 40
           ++ k+++l++MGFd+++++ aL + ++++e A+e+Ll+
   Q: 162  YTRKIDKLCAMGFDKNAVIAALSSKSWDVETATELLLS 199
           6789********************************97 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MANIAVQRIK REFKEVIKSE ETIKNQIKVE LVGDNFTELR GEIAGPPDTP YEGGKYHLEI 60
KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAACA TCGCGGTCCA GCGGATCAAG CGGGAGTTTA AAGAAGTTAT CAAGAGCGAA 60
GAGGTGCGGT AATGTTAGAA CCCTTTAGCC GGAAGGCAAA GCGGCTGTAG ATGTTTTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

tru:101064571

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003063	Amborella trichopoda	48.45	1.00e-40	159.00
IUUC-Apl-004122	Anas platyrhynchos	84.50	3.00e-90	323.00
IUUC-Aca-004565	Anolis carolinensis	85.79	3.00e-91	327.00
IUUC-Aly-006390	Arabidopsis lyrata	47.72	1.00e-44	172.00
IUUC-Ath-006637	Arabidopsis thaliana	44.93	3.00e-41	161.00
IUUC-Afl-008489	Aspergillus flavus	40.93	1.00e-27	116.00
IUUC-Afu-008850	Aspergillus fumigatus	42.06	5.00e-29	121.00
IUUC-Ani-009361	Aspergillus nidulans	51.35	7.00e-27	113.00
IUUC-Ang-009548	Aspergillus niger	40.47	3.00e-27	114.00
IUUC-Aor-010105	Aspergillus oryzae	40.93	1.00e-27	116.00
IUUC-Ate-010389	Aspergillus terreus	41.28	5.00e-28	117.00
IUUC-Bdi-015024	Brachypodium distachyon	48.73	2.00e-41	161.00
IUUC-Bol-015985	Brassica oleracea	47.72	1.00e-44	172.00
IUUC-Bra-016805	Brassica rapa	47.72	6.00e-45	173.00
IUUC-Cel-018353	Caenorhabditis elegans	52.26	2.00e-57	214.00
IUUC-Cja-019051	Callithrix jacchus	91.00	4.00e-101	360.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	48.98	1.00e-41	162.00
IUUC-Cho-024276	Choloepus hoffmanni	88.44	2.00e-68	250.00
IUUC-Cin-025598	Ciona intestinalis	62.76	1.00e-56	212.00
IUUC-Csv-025831	Ciona savignyi	64.29	6.00e-55	206.00
IUUC-Dre-028139	Danio rerio	93.50	1.00e-103	368.00
IUUC-Dno-029169	Dasypus novemcinctus	86.00	1.00e-94	338.00
IUUC-Dor-030382	Dipodomys ordii	77.50	2.00e-80	291.00
IUUC-Dme-032003	Drosophila melanogaster	70.35	7.00e-73	266.00
IUUC-Ete-032868	Echinops telfairi	83.50	5.00e-81	293.00
IUUC-Eeu-035103	Erinaceus europaeus	65.62	7.00e-45	172.00
IUUC-Gga-041018	Gallus gallus	92.00	2.00e-102	364.00
IUUC-Gma-042779	Glycine max	50.26	1.00e-43	168.00
IUUC-Lpe-051070	Leersia perrieri	48.73	1.00e-33	135.00
IUUC-Lma-052949	Leptosphaeria maculans	41.86	1.00e-37	149.00
IUUC-Laf-053688	Loxodonta africana	84.31	3.00e-92	330.00
IUUC-Mtr-058002	Medicago truncatula	49.74	4.00e-43	167.00
IUUC-Mla-059007	Melampsora laricipopulina	43.65	3.00e-38	151.00
IUUC-Mga-059254	Meleagris gallopavo	91.11	2.00e-90	324.00
IUUC-Mdo-062458	Monodelphis domestica	91.50	5.00e-100	356.00
IUUC-Mac-065447	Musa acuminata	48.22	1.00e-41	162.00
IUUC-Mlu-067682	Myotis lucifugus	84.85	3.00e-92	330.00
IUUC-Nfi-068517	Neosartorya fischeri	42.06	5.00e-29	120.00
IUUC-Nle-069712	Nomascus leucogenys	91.11	2.00e-90	324.00
IUUC-Ont-071433	Oreochromis niloticus	95.00	5.00e-105	373.00
IUUC-Oan-073058	Ornithorhynchus anatinus	91.89	1.00e-73	267.00
IUUC-Oba-075530	Oryza barthii	49.24	8.00e-33	132.00
IUUC-Obr-076838	Oryza brachyantha	48.73	4.00e-32	130.00
IUUC-Ogl-077606	Oryza glaberrima	49.24	8.00e-33	132.00
IUUC-Ogu-078238	Oryza glumaepatula	49.24	8.00e-33	132.00
IUUC-Oin-079643	Oryza indica	49.24	2.00e-32	131.00
IUUC-Ome-081274	Oryza meridionalis	49.24	8.00e-33	132.00
IUUC-Oni-082651	Oryza nivara	49.24	8.00e-33	132.00
IUUC-Opu-083933	Oryza punctata	49.24	2.00e-32	132.00
IUUC-Oru-085054	Oryza rufipogon	49.24	2.00e-32	131.00
IUUC-Osa-085716	Oryza sativa	49.24	2.00e-32	131.00
IUUC-Ola-087278	Oryzias latipes	94.50	4.00e-104	370.00
IUUC-Olu-087846	Ostreococcus lucimarinus	48.19	2.00e-45	174.00
IUUC-Oga-088897	Otolemur garnettii	85.35	5.00e-92	330.00
IUUC-Oar-089673	Ovis aries	84.85	5.00e-93	333.00
IUUC-Pan-092034	Papio anubis	91.06	7.00e-90	322.00
IUUC-Pma-094115	Petromyzon marinus	81.41	8.00e-87	312.00
IUUC-Pno-095102	Phaeosphaeria nodorum	41.71	8.00e-39	153.00
IUUC-Ppa-095326	Physcomitrella patens	46.19	1.00e-39	155.00
IUUC-Pfo-096940	Poecilia formosa	95.00	5.00e-105	373.00
IUUC-Pop-099543	Populus trichocarpa	49.24	6.00e-45	173.00
IUUC-Ppe-101789	Prunus persica	48.45	9.00e-38	149.00
IUUC-Pgr-103643	Puccinia graminis	48.05	5.00e-39	154.00
IUUC-Pte-104370	Pyrenophora teres	41.40	2.00e-37	149.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	40.93	4.00e-37	147.00
IUUC-Sha-106624	Sarcophilus harrisii	86.00	3.00e-96	343.00
IUUC-Smo-109656	Selaginella moellendorffii	48.45	7.00e-41	159.00
IUUC-Sit-110639	Setaria italica	48.22	6.00e-40	156.00
IUUC-Sly-110978	Solanum lycopersicum	49.24	9.00e-46	176.00
IUUC-Stu-112088	Solanum tuberosum	49.24	4.00e-46	177.00
IUUC-Sar-113285	Sorex araneus	75.42	2.00e-68	251.00
IUUC-Sbi-113986	Sorghum bicolor	48.22	7.00e-40	156.00
IUUC-Tgu-117427	Taeniopygia guttata	90.56	6.00e-90	322.00
IUUC-Tsy-119208	Tarsius syrichta	89.39	2.00e-98	351.00
IUUC-Tni-120673	Tetraodon nigroviridis	94.58	2.00e-104	370.00
IUUC-Tca-121446	Theobroma cacao	49.75	6.00e-46	176.00
IUUC-Tae-124726	Triticum aestivum	49.24	4.00e-34	137.00
IUUC-Ttr-128287	Tursiops truncatus	91.06	7.00e-90	322.00
IUUC-Uma-129512	Ustilago maydis	39.71	5.00e-36	144.00
IUUC-Vpa-130481	Vicugna pacos	91.37	6.00e-100	356.00
IUUC-Vvi-131429	Vitis vinifera	46.70	1.00e-42	165.00
IUUC-Xtr-132710	Xenopus tropicalis	75.74	3.00e-88	317.00
IUUC-Xma-134308	Xiphophorus maculatus	94.50	2.00e-104	371.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence