iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015925

Ensembl Protein ID

Bo1g002670.1

UniProt Accession

A0A0D3A0Z0; A0A0D3A0Z0_BRAOL

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo1g002670	Bo1g002670.1	Bo1g002670.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-38	130.6	50	86
UBD/Beta-Prp	1.60e-77	262.1	3	322

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H+++v++++f ++ +l+vsG+dD +ikvW+ +t+++l
   Q: 50   HEGPVRGVHFhNSqPLFVSGGDDYKIKVWNHKTHRCL 86
           9*********9777****************9999997 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
           t +++++++++ ++f+p++++++++  +g i++wd+++g+l+ ++ +he++v+ v f+++++++v+g++D+ ikvw+ +t  c+ tl gh d+++++
   Q: 3    TKFETKSNRVKGLTFHPKRPWILASLHSGVIQLWDYRMGTLIDRFDEHEGPVRGVHFHNSQPLFVSGGDDYKIKVWNHKTHRCLFTLLGHLDYIRTV 99
           67889999***************************************************************************************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......................ktgkllrtl 175
           +f+ ++ ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                              l
   Q: 100  QFHHENPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgslkkktvspaddlmrftqmnsD-------L 188
           ******************************.*******************************************999999955555550.......4 PP
   S: 176  ...........tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllkt 259
                       +gh++ v++ sf+++ + +vsg++d++vklw + +++   v+tl+gh +nv+sv f+ +++++vs s+D+sir+Wd ++++ ++t
   Q: 189  fggvdaivkyvLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNETKAweVDTLRGHMNNVSSVMFHAKQDIIVSNSEDKSIRVWDATKRTGIQT 285
           55555555556555********************************887778********************************************* PP
   S: 260  lqlhnssvisvavlsfgdnvlvlgsedskvniwklkkne 298
           + +++++++  av +++ n l++g + +   ++kl++++
   Q: 286  FRREHDRFWILAV-HPEINLLAAGHD-NGMIVFKLERER 322
           *************.888777777755.566677887766 PP

Organism

Brassica oleracea

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLTFHPK RPWILASLHS GVIQLWDYRM GTLIDRFDEH EGPVRGVHFH 60
NSQPLFVSGG DDYKIKVWNH KTHRCLFTLL GHLDYIRTVQ FHHENPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGACGA AGTTCGAGAC GAAGAGTAAC AGAGTGAAGG GCCTCACCTT CCACCCTAAG 60
CGACCATGGA TCCTCGCCAG TTTGCACAGT GGTGTGATCC AGCTCTGGGA TTATCGTATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000201	Aegilops tauschii	75.21	0.00e+00	1898.00
IUUC-Aml-001758	Ailuropoda melanoleuca	53.61	0.00e+00	1333.00
IUUC-Atr-002493	Amborella trichopoda	78.13	0.00e+00	1963.00
IUUC-Apl-003385	Anas platyrhynchos	49.68	0.00e+00	1025.00
IUUC-Aly-006020	Arabidopsis lyrata	92.22	0.00e+00	2224.00
IUUC-Ath-007360	Arabidopsis thaliana	91.73	0.00e+00	2222.00
IUUC-Ago-007992	Ashbya gossypii	43.23	0.00e+00	960.00
IUUC-Acl-008027	Aspergillus clavatus	55.80	0.00e+00	976.00
IUUC-Afl-008644	Aspergillus flavus	55.77	0.00e+00	970.00
IUUC-Afu-008964	Aspergillus fumigatus	55.82	0.00e+00	979.00
IUUC-Ani-009379	Aspergillus nidulans	55.60	0.00e+00	984.00
IUUC-Ang-009756	Aspergillus niger	55.68	0.00e+00	981.00
IUUC-Aor-010174	Aspergillus oryzae	55.77	0.00e+00	970.00
IUUC-Ate-010302	Aspergillus terreus	46.75	0.00e+00	1116.00
IUUC-Ame-011229	Astyanax mexicanus	52.67	0.00e+00	1297.00
IUUC-Bgr-012300	Blumeria graminis	46.56	0.00e+00	1083.00
IUUC-Bta-012524	Bos taurus	54.00	0.00e+00	1326.00
IUUC-Bdi-014549	Brachypodium distachyon	75.63	0.00e+00	1960.00
IUUC-Bra-016978	Brassica rapa	96.72	0.00e+00	2304.00
IUUC-Cel-018115	Caenorhabditis elegans	54.52	0.00e+00	939.00
IUUC-Cja-019107	Callithrix jacchus	53.17	0.00e+00	1314.00
IUUC-Cfa-020675	Canis familiaris	53.26	0.00e+00	1307.00
IUUC-Cpo-021813	Cavia porcellus	54.32	0.00e+00	1345.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	71.02	0.00e+00	1260.00
IUUC-Csa-023523	Chlorocebus sabaeus	54.08	0.00e+00	1345.00
IUUC-Cin-025572	Ciona intestinalis	50.40	0.00e+00	1228.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.23	0.00e+00	977.00
IUUC-Cne-027053	Cryptococcus neoformans	57.72	0.00e+00	1017.00
IUUC-Dre-027421	Danio rerio	53.84	0.00e+00	1318.00
IUUC-Dno-029303	Dasypus novemcinctus	54.28	0.00e+00	1350.00
IUUC-Dor-030290	Dipodomys ordii	52.72	8.00e-163	568.00
IUUC-Dse-031543	Dothistroma septosporum	46.46	0.00e+00	1084.00
IUUC-Dme-031945	Drosophila melanogaster	60.72	0.00e+00	1033.00
IUUC-Eca-033773	Equus caballus	53.29	0.00e+00	1306.00
IUUC-Eeu-034874	Erinaceus europaeus	40.82	0.00e+00	635.00
IUUC-Fca-035739	Felis catus	53.54	0.00e+00	1312.00
IUUC-Fal-037263	Ficedula albicollis	50.81	0.00e+00	1187.00
IUUC-Fox-037738	Fusarium oxysporum	46.43	0.00e+00	1134.00
IUUC-Fso-038153	Fusarium solani	46.89	0.00e+00	1122.00
IUUC-Gmo-039602	Gadus morhua	50.32	0.00e+00	1213.00
IUUC-Ggr-039931	Gaeumannomyces graminis	54.56	0.00e+00	963.00
IUUC-Gga-040590	Gallus gallus	54.64	0.00e+00	1345.00
IUUC-Gac-041318	Gasterosteus aculeatus	53.49	0.00e+00	1330.00
IUUC-Gma-043894	Glycine max	81.59	0.00e+00	2071.00
IUUC-Ggo-045029	Gorilla gorilla	53.69	0.00e+00	1337.00
IUUC-Hsa-046078	Homo sapiens	53.69	0.00e+00	1337.00
IUUC-Hvu-047556	Hordeum vulgare	75.81	0.00e+00	1976.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	45.21	0.00e+00	741.00
IUUC-Loc-051867	Lepisosteus oculatus	50.06	0.00e+00	813.00
IUUC-Laf-053510	Loxodonta africana	54.93	0.00e+00	1362.00
IUUC-Mcc-055836	Macaca mulatta	53.68	0.00e+00	1332.00
IUUC-Meu-056238	Macropus eugenii	56.72	0.00e+00	768.00
IUUC-Mtr-058248	Medicago truncatula	80.77	0.00e+00	2075.00
IUUC-Mga-059499	Meleagris gallopavo	54.55	0.00e+00	1342.00
IUUC-Mvi-060336	Microbotryum violaceum	50.28	0.00e+00	1209.00
IUUC-Mmr-061102	Microcebus murinus	53.77	0.00e+00	1330.00
IUUC-Mdo-062594	Monodelphis domestica	54.68	0.00e+00	1362.00
IUUC-Mmu-063736	Mus musculus	53.85	0.00e+00	1334.00
IUUC-Mac-065272	Musa acuminata	69.48	0.00e+00	1751.00
IUUC-Mpu-066701	Mustela putorius furo	54.13	0.00e+00	1340.00
IUUC-Mlu-067392	Myotis lucifugus	54.16	0.00e+00	1333.00
IUUC-Nfi-068270	Neosartorya fischeri	55.90	0.00e+00	978.00
IUUC-Ncr-068892	Neurospora crassa	56.42	0.00e+00	986.00
IUUC-Nle-069634	Nomascus leucogenys	65.92	0.00e+00	941.00
IUUC-Opr-070952	Ochotona princeps	41.24	0.00e+00	644.00
IUUC-Ont-072488	Oreochromis niloticus	53.56	0.00e+00	1315.00
IUUC-Ocu-074211	Oryctolagus cuniculus	54.16	0.00e+00	1343.00
IUUC-Oba-075761	Oryza barthii	76.23	0.00e+00	1967.00
IUUC-Obr-076429	Oryza brachyantha	76.49	0.00e+00	1974.00
IUUC-Opu-083885	Oryza punctata	76.35	0.00e+00	1969.00
IUUC-Ola-086921	Oryzias latipes	53.05	0.00e+00	1300.00
IUUC-Olu-087639	Ostreococcus lucimarinus	61.67	0.00e+00	1543.00
IUUC-Oga-087991	Otolemur garnettii	50.97	0.00e+00	1243.00
IUUC-Oar-089590	Ovis aries	53.91	0.00e+00	1340.00
IUUC-Ptr-090808	Pan troglodytes	53.77	0.00e+00	1340.00
IUUC-Pan-092475	Papio anubis	53.95	0.00e+00	1338.00
IUUC-Pno-094839	Phaeosphaeria nodorum	45.94	0.00e+00	1048.00
IUUC-Ppa-095254	Physcomitrella patens	68.79	0.00e+00	1766.00
IUUC-Pfo-097493	Poecilia formosa	53.96	0.00e+00	1315.00
IUUC-Pab-098497	Pongo abelii	54.08	0.00e+00	1347.00
IUUC-Pop-099992	Populus trichocarpa	83.63	0.00e+00	2072.00
IUUC-Pca-100413	Procavia capensis	60.07	0.00e+00	686.00
IUUC-Ppe-101899	Prunus persica	82.65	0.00e+00	2091.00
IUUC-Pva-102126	Pteropus vampyrus	51.69	0.00e+00	1265.00
IUUC-Ptt-103978	Puccinia triticina	52.31	0.00e+00	840.00
IUUC-Pte-104126	Pyrenophora teres	54.74	0.00e+00	933.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	45.65	2.00e-171	596.00
IUUC-Rno-105428	Rattus norvegicus	54.08	0.00e+00	1340.00
IUUC-Sce-106464	Saccharomyces cerevisiae	43.01	0.00e+00	944.00
IUUC-Sha-107301	Sarcophilus harrisii	53.80	0.00e+00	1325.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.66	0.00e+00	1066.00
IUUC-Spo-108217	Schizosaccharomyces pombe	45.16	0.00e+00	1055.00
IUUC-Sit-109697	Setaria italica	76.49	0.00e+00	1971.00
IUUC-Sly-111759	Solanum lycopersicum	80.93	0.00e+00	2079.00
IUUC-Stu-112564	Solanum tuberosum	80.85	0.00e+00	2074.00
IUUC-Sar-113313	Sorex araneus	44.07	3.00e-170	592.00
IUUC-Sre-115209	Sporisorium reilianum	55.78	0.00e+00	1005.00
IUUC-Ssc-115933	Sus scrofa	54.08	0.00e+00	1343.00
IUUC-Tgu-117109	Taeniopygia guttata	44.55	6.00e-107	380.00
IUUC-Tru-117772	Takifugu rubripes	52.53	0.00e+00	1285.00
IUUC-Tni-120556	Tetraodon nigroviridis	41.71	0.00e+00	873.00
IUUC-Tca-120918	Theobroma cacao	87.76	0.00e+00	1574.00
IUUC-Tre-121951	Trichoderma reesei	54.98	0.00e+00	967.00
IUUC-Tae-125527	Triticum aestivum	76.25	0.00e+00	1954.00
IUUC-Tur-126754	Triticum urartu	74.94	0.00e+00	1912.00
IUUC-Tme-127170	Tuber melanosporum	48.78	0.00e+00	1183.00
IUUC-Tbe-127882	Tupaia belangeri	67.42	1.00e-126	447.00
IUUC-Ttr-128217	Tursiops truncatus	51.92	0.00e+00	1270.00
IUUC-Vda-129828	Verticillium dahliae	54.48	0.00e+00	954.00
IUUC-Vpa-130537	Vicugna pacos	53.44	0.00e+00	1313.00
IUUC-Vvi-130958	Vitis vinifera	80.69	0.00e+00	2075.00
IUUC-Xtr-132857	Xenopus tropicalis	52.65	0.00e+00	1256.00
IUUC-Xma-133138	Xiphophorus maculatus	53.96	0.00e+00	1319.00
IUUC-Yli-134399	Yarrowia lipolytica	49.48	0.00e+00	840.00
IUUC-Zma-135612	Zea mays	74.96	0.00e+00	1956.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence