iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Rno-105666

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

COP9 signalosome subunit 5

Genbank Nucleotide ID

AABR07046831

Gene Name

Cops5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000006499.6	ENSRNOT00000008877.6	ENSRNOP00000008877.5

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/JAMM	1.50e-07	31.6	193	206

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/JAMM

   S: 1    HSHPgftcwlSsVD 14
           HSHPg++cwlS++D
   Q: 193  HSHPGYGCWLSGID 206
           *************9 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MVWTNVTSGL KCHGCLESLV SVHPWWGRCK ARTLRPSRIK LHLGCGDYSF SGPSAMTASG 60
SGMAQKTWEL ANNMQEAQSI DEIYKYDKKQ QQEILAAKPW TKDHHYFKYC KISALALLKM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCCGCCTT CCGGCGCGAA AGGCCGTACC ATTCCCACAC AGAGACTTTG CGTCCCTCCC 60
AGTTCACACG TACGGATTTC AGAGCCAGCA TGTCCTCGTT TCGTTCGCAA AACTATTATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000555--JAMM/MPN+_dom

Pfam

PF01398--JAB

SMART

SM00232--JAB_MPN

Gene Ontology

GO:0008180--C:COP9 signalosome
GO:0005654--C:nucleoplasm
GO:0008021--C:synaptic vesicle
GO:0008237--F:metallopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1990182--P:exosomal secretion
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0000338--P:protein deneddylation
GO:0016579--P:protein deubiquitination
GO:0051726--P:regulation of cell cycle
GO:1903894--P:regulation of IRE1-mediated unfolded protein response
GO:0046328--P:regulation of JNK cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000468	Aegilops tauschii	66.57	1.00e-121	429.00
IUUC-Aml-001429	Ailuropoda melanoleuca	99.38	6.00e-180	622.00
IUUC-Atr-003048	Amborella trichopoda	68.02	6.00e-125	440.00
IUUC-Apl-003610	Anas platyrhynchos	90.36	6.00e-163	566.00
IUUC-Aca-004662	Anolis carolinensis	98.62	1.00e-155	541.00
IUUC-Aly-005914	Arabidopsis lyrata	67.06	2.00e-122	432.00
IUUC-Ath-007496	Arabidopsis thaliana	67.16	3.00e-122	431.00
IUUC-Ago-007860	Ashbya gossypii	46.77	4.00e-47	182.00
IUUC-Acl-008155	Aspergillus clavatus	55.05	1.00e-97	349.00
IUUC-Afu-008820	Aspergillus fumigatus	55.35	7.00e-98	350.00
IUUC-Ani-009303	Aspergillus nidulans	54.74	5.00e-96	344.00
IUUC-Ang-009617	Aspergillus niger	54.09	2.00e-93	335.00
IUUC-Aor-009888	Aspergillus oryzae	56.49	4.00e-95	341.00
IUUC-Ate-010575	Aspergillus terreus	56.75	3.00e-100	358.00
IUUC-Ame-010617	Astyanax mexicanus	95.21	1.00e-178	618.00
IUUC-Bgr-012019	Blumeria graminis	56.17	7.00e-100	357.00
IUUC-Bta-013211	Bos taurus	98.80	0.00e+00	637.00
IUUC-Bci-013645	Botrytis cinerea	57.89	4.00e-104	370.00
IUUC-Bdi-014727	Brachypodium distachyon	67.76	4.00e-118	417.00
IUUC-Bol-015205	Brassica oleracea	67.37	2.00e-120	425.00
IUUC-Bra-017649	Brassica rapa	67.37	2.00e-120	425.00
IUUC-Cel-018469	Caenorhabditis elegans	57.06	7.00e-104	370.00
IUUC-Cja-019703	Callithrix jacchus	99.10	0.00e+00	638.00
IUUC-Cfa-020181	Canis familiaris	99.40	0.00e+00	639.00
IUUC-Cpo-021499	Cavia porcellus	99.10	0.00e+00	638.00
IUUC-Cre-022735	Chlamydomonas reinhardtii	60.31	3.00e-111	394.00
IUUC-Csa-024200	Chlorocebus sabaeus	99.10	0.00e+00	638.00
IUUC-Cho-024915	Choloepus hoffmanni	97.12	4.00e-118	417.00
IUUC-Cin-025353	Ciona intestinalis	79.94	2.00e-137	481.00
IUUC-Csv-026118	Ciona savignyi	80.24	2.00e-138	485.00
IUUC-Cgl-026511	Colletotrichum gloeosporioides	52.37	4.00e-95	341.00
IUUC-Cne-026988	Cryptococcus neoformans	49.14	3.00e-85	308.00
IUUC-Dre-028134	Danio rerio	96.07	2.00e-178	618.00
IUUC-Dno-029658	Dasypus novemcinctus	99.10	0.00e+00	638.00
IUUC-Dor-031074	Dipodomys ordii	99.10	0.00e+00	638.00
IUUC-Dse-031497	Dothistroma septosporum	56.68	5.00e-98	350.00
IUUC-Dme-032199	Drosophila melanogaster	74.47	2.00e-142	498.00
IUUC-Ete-032739	Echinops telfairi	98.22	2.00e-85	309.00
IUUC-Eca-034095	Equus caballus	99.11	0.00e+00	643.00
IUUC-Eeu-034934	Erinaceus europaeus	84.13	3.00e-147	514.00
IUUC-Fca-035569	Felis catus	99.10	0.00e+00	638.00
IUUC-Fal-037553	Ficedula albicollis	99.30	1.00e-155	541.00
IUUC-Fox-037945	Fusarium oxysporum	49.85	1.00e-87	316.00
IUUC-Fso-038385	Fusarium solani	54.38	2.00e-94	338.00
IUUC-Gmo-039438	Gadus morhua	94.33	2.00e-174	604.00
IUUC-Ggr-039968	Gaeumannomyces graminis	51.57	5.00e-95	340.00
IUUC-Gga-040344	Gallus gallus	99.08	2.00e-179	621.00
IUUC-Gac-042256	Gasterosteus aculeatus	96.37	2.00e-175	607.00
IUUC-Gma-043226	Glycine max	67.05	3.00e-124	438.00
IUUC-Ggo-044523	Gorilla gorilla	92.40	4.00e-162	563.00
IUUC-Hsa-046659	Homo sapiens	99.10	0.00e+00	638.00
IUUC-Itr-048834	Ictidomys tridecemlineatus	99.70	0.00e+00	636.00
IUUC-Kpa-049139	Komagataella pastoris	58.49	2.00e-52	200.00
IUUC-Lch-049562	Latimeria chalumnae	96.98	9.00e-180	622.00
IUUC-Lpe-050737	Leersia perrieri	67.66	4.00e-127	447.00
IUUC-Loc-051798	Lepisosteus oculatus	97.23	6.00e-174	603.00
IUUC-Lma-052979	Leptosphaeria maculans	49.73	1.00e-93	336.00
IUUC-Laf-053391	Loxodonta africana	99.55	4.00e-120	423.00
IUUC-Mcc-055667	Macaca mulatta	99.10	0.00e+00	638.00
IUUC-Meu-056067	Macropus eugenii	68.60	4.00e-83	300.00
IUUC-Mor-057084	Magnaporthe oryzae	53.31	3.00e-97	348.00
IUUC-Mpo-057347	Magnaporthe poae	54.01	2.00e-97	348.00
IUUC-Mtr-057781	Medicago truncatula	68.67	2.00e-125	442.00
IUUC-Mla-059106	Melampsora laricipopulina	51.56	4.00e-104	371.00
IUUC-Mga-059473	Meleagris gallopavo	99.30	1.00e-155	541.00
IUUC-Mvi-060540	Microbotryum violaceum	54.70	1.00e-109	389.00
IUUC-Mmr-061138	Microcebus murinus	96.41	5.00e-97	346.00
IUUC-Mdo-062893	Monodelphis domestica	98.80	0.00e+00	637.00
IUUC-Mmu-063637	Mus musculus	99.70	0.00e+00	640.00
IUUC-Mac-064683	Musa acuminata	67.16	2.00e-127	448.00
IUUC-Mpu-066096	Mustela putorius furo	85.97	9.00e-150	522.00
IUUC-Mlu-067872	Myotis lucifugus	95.81	2.00e-176	611.00
IUUC-Nfi-068443	Neosartorya fischeri	55.05	1.00e-96	346.00
IUUC-Ncr-068953	Neurospora crassa	52.61	1.00e-90	326.00
IUUC-Nle-068972	Nomascus leucogenys	99.10	0.00e+00	638.00
IUUC-Opr-070215	Ochotona princeps	88.62	8.00e-157	546.00
IUUC-Ont-072538	Oreochromis niloticus	96.37	9.00e-175	605.00
IUUC-Oan-073143	Ornithorhynchus anatinus	98.20	0.00e+00	634.00
IUUC-Ocu-074197	Oryctolagus cuniculus	99.10	0.00e+00	638.00
IUUC-Oba-075884	Oryza barthii	62.22	1.00e-119	422.00
IUUC-Obr-076874	Oryza brachyantha	66.47	3.00e-124	437.00
IUUC-Ogl-077169	Oryza glaberrima	67.46	1.00e-123	436.00
IUUC-Ogu-078258	Oryza glumaepatula	67.16	2.00e-123	435.00
IUUC-Oin-079101	Oryza indica	62.78	6.00e-120	423.00
IUUC-Olo-080708	Oryza longistaminata	55.28	6.00e-96	343.00
IUUC-Ome-081571	Oryza meridionalis	62.50	6.00e-120	423.00
IUUC-Oni-082888	Oryza nivara	62.78	6.00e-120	423.00
IUUC-Opu-083182	Oryza punctata	67.46	1.00e-123	436.00
IUUC-Oru-084895	Oryza rufipogon	62.78	6.00e-120	423.00
IUUC-Osa-085331	Oryza sativa	67.46	1.00e-123	436.00
IUUC-Ola-086850	Oryzias latipes	96.68	1.00e-175	608.00
IUUC-Olu-087607	Ostreococcus lucimarinus	57.69	4.00e-80	291.00
IUUC-Oga-088640	Otolemur garnettii	99.38	6.00e-180	622.00
IUUC-Oar-090299	Ovis aries	99.08	1.00e-179	621.00
IUUC-Ptr-091499	Pan troglodytes	99.10	0.00e+00	638.00
IUUC-Pan-091751	Papio anubis	77.89	2.00e-155	541.00
IUUC-Psi-092978	Pelodiscus sinensis	98.15	4.00e-178	617.00
IUUC-Pma-094634	Petromyzon marinus	93.52	2.00e-169	587.00
IUUC-Pno-095094	Phaeosphaeria nodorum	50.00	4.00e-93	334.00
IUUC-Ppa-095440	Physcomitrella patens	68.53	1.00e-127	449.00
IUUC-Pfo-097332	Poecilia formosa	96.68	1.00e-175	608.00
IUUC-Pab-097998	Pongo abelii	99.10	0.00e+00	638.00
IUUC-Pop-098905	Populus trichocarpa	66.37	1.00e-129	455.00
IUUC-Pca-100521	Procavia capensis	100.00	3.00e-61	228.00
IUUC-Ppe-101309	Prunus persica	67.75	6.00e-130	457.00
IUUC-Pva-102953	Pteropus vampyrus	99.10	0.00e+00	638.00
IUUC-Pgr-103452	Puccinia graminis	60.59	1.00e-90	326.00
IUUC-Ptt-103777	Puccinia triticina	62.65	2.00e-87	316.00
IUUC-Pte-104273	Pyrenophora teres	52.38	1.00e-93	336.00
IUUC-Pyt-104627	Pyrenophora triticirepentis	53.56	2.00e-92	332.00
IUUC-Sce-106319	Saccharomyces cerevisiae	40.29	5.00e-34	138.00
IUUC-Sha-106602	Sarcophilus harrisii	98.80	0.00e+00	637.00
IUUC-Sja-107822	Schizosaccharomyces japonicus	45.89	2.00e-47	182.00
IUUC-Spo-108318	Schizosaccharomyces pombe	40.58	3.00e-64	238.00
IUUC-Ssl-108428	Sclerotinia sclerotiorum	58.51	4.00e-105	374.00
IUUC-Smo-108821	Selaginella moellendorffii	66.37	3.00e-124	437.00
IUUC-Sit-110526	Setaria italica	66.08	3.00e-117	415.00
IUUC-Sly-111466	Solanum lycopersicum	67.16	1.00e-131	462.00
IUUC-Stu-112776	Solanum tuberosum	67.74	5.00e-132	463.00
IUUC-Sar-113459	Sorex araneus	99.40	0.00e+00	639.00
IUUC-Sbi-114873	Sorghum bicolor	66.96	5.00e-121	427.00
IUUC-Sre-114919	Sporisorium reilianum	64.64	2.00e-92	332.00
IUUC-Ssc-116102	Sus scrofa	99.10	0.00e+00	638.00
IUUC-Tgu-116937	Taeniopygia guttata	99.61	2.00e-138	484.00
IUUC-Tru-118615	Takifugu rubripes	96.98	3.00e-176	610.00
IUUC-Tsy-119173	Tarsius syrichta	99.04	2.00e-171	594.00
IUUC-Tni-120246	Tetraodon nigroviridis	96.98	2.00e-176	611.00
IUUC-Tca-121859	Theobroma cacao	68.48	1.00e-127	449.00
IUUC-Tre-122030	Trichoderma reesei	52.44	3.00e-95	341.00
IUUC-Tvi-122506	Trichoderma virens	53.80	4.00e-100	357.00
IUUC-Tae-125382	Triticum aestivum	66.57	2.00e-121	428.00
IUUC-Tur-126517	Triticum urartu	68.71	1.00e-118	419.00
IUUC-Tme-127122	Tuber melanosporum	55.99	8.00e-102	363.00
IUUC-Tbe-128108	Tupaia belangeri	97.90	7.00e-180	622.00
IUUC-Ttr-128644	Tursiops truncatus	99.10	0.00e+00	638.00
IUUC-Uma-129390	Ustilago maydis	52.23	1.00e-93	336.00
IUUC-Vda-129932	Verticillium dahliae	47.84	1.00e-88	319.00
IUUC-Vpa-130110	Vicugna pacos	99.10	0.00e+00	638.00
IUUC-Vvi-131534	Vitis vinifera	68.24	9.00e-132	462.00
IUUC-Xtr-132739	Xenopus tropicalis	97.01	0.00e+00	629.00
IUUC-Xma-133919	Xiphophorus maculatus	96.68	1.00e-175	608.00
IUUC-Yli-134677	Yarrowia lipolytica	48.84	3.00e-90	325.00
IUUC-Zma-135578	Zea mays	67.56	6.00e-122	430.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence