iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004339

Ensembl Protein ID

ENSACAP00000007083.3

UniProt Accession

H9GCG4; H9GCG4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

WDR36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007141.3	ENSACAT00000007236.3	ENSACAP00000007083.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-22	78.5	565	602
UBD/Beta-Prp	2.40e-49	168.0	229	525

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH+  ++++ f +d + l+++s D+ti+ WDl +g l+
   Q: 565  GHQRQINDFTFsPDgRWLLTASMDCTIRTWDLPSGCLV 602
           8***********99999***************999875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcvht 89
           +++ ++it++ f +++ +++a+gs  g i +wd++++kll ++   h+ +++ ++f + +++l+t s+D++i+vw ++    +g  ++ 
   Q: 229  QQDWGPITAISFrTDGHPVMAAGSPVGHIGLWDLEEKKLLGQMrNAHSTAIAGMSFVQGEPLLITNSSDNAIRVWIFDgpggNGRLLRC 317
           33445566666655555666666666666666666666666665566666666666666666666666666666633333446666666 PP
   S: 90   lkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee.....................tlsghdgvvncvvvhpdgnllvsGs 156
             gh++  + ++++  +g+ ++s+++d+t++ + + ++   ++                     +l + + + + v+ ++d + +v+++
   Q: 318  RMGHSAPPTKIRYHGqNGHQILSAGQDSTLQSFSTVHERFNKNlgrgsinkkkskkkgllydtmVLPPITTFASEVARQSDWDGIVACH 406
           66666666666666545566666666666666544444444445555555555555566666665555555555555555555555555 PP
   S: 157  lDr.tvrlWdl.ktgkllrtl.....tgghtdsvyslsfdsng..kelvsgsldgtvklwdlq...tgecvrtlnghtdnvksvrfspn 233
               t+  W+  kt   +++l     ++++   vy +++d ++  ++ v g + g+v ++++q   +  c  + ++h++ ++ v+++  
   Q: 407  QGYvTCTSWNYhKTSMGIHKLkpkdfSKNKPLGVYATAVDITScgNFAVIGLTTGQVDVYNMQsgiHRGCYGKEKAHESSIRGVAVDGL 495
           543245555554455556666666555555555655553333376******************999778******************** PP
   S: 234  derlvsgssDgsiriWdlrsgdllktlqlh 263
           +++ ++++s+g +++W  ++++l+++++l 
   Q: 496  NQLTITAGSEGLVKFWKFKTKELVHSTNLF 525
           *************************99886 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MALKGGGGQS ALLAGFRALG LYSNHLPHVL RFHRRHREFY LAVAVGSSFH TYNVKKLGIV 60
AVSNALPENI TCLAADRLLV FASCGSLLHA FARNKEVVRT YKGHKADIHL LMPFGDHVIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGTTGGCA TGCAGCAACT GTGAATGCTG CATCTCAGAG TGGTCCGCGA GAAGCGAGAA 60
AGCGCGCGGG GGGGGGGGGG GGAGAGAGAG AGAGATAAAG AAATGACTTT CTTAAACATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020719--RNA3'_term_phos_cycl-like_CS
IPR007319--SSU_processome_Utp21
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS01287--RTC
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04192--Utp21
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0003723--F:RNA binding
GO:0030516--P:regulation of axon extension
GO:0001895--P:retina homeostasis
GO:0006364--P:rRNA processing

KEGG

acs:100554955

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001096	Aegilops tauschii	35.96	1.00e-145	510.00
IUUC-Aml-002289	Ailuropoda melanoleuca	71.92	0.00e+00	1295.00
IUUC-Atr-002859	Amborella trichopoda	34.03	3.00e-127	449.00
IUUC-Apl-003505	Anas platyrhynchos	81.97	0.00e+00	1333.00
IUUC-Aly-005913	Arabidopsis lyrata	36.20	6.00e-152	531.00
IUUC-Ath-006767	Arabidopsis thaliana	36.02	5.00e-154	538.00
IUUC-Ago-007763	Ashbya gossypii	29.97	6.00e-110	392.00
IUUC-Acl-008275	Aspergillus clavatus	30.93	1.00e-85	311.00
IUUC-Afl-008457	Aspergillus flavus	32.04	5.00e-84	305.00
IUUC-Afu-008914	Aspergillus fumigatus	29.95	3.00e-90	326.00
IUUC-Ani-009225	Aspergillus nidulans	30.15	2.00e-91	330.00
IUUC-Aor-010046	Aspergillus oryzae	30.16	7.00e-105	375.00
IUUC-Ate-010337	Aspergillus terreus	30.87	4.00e-103	369.00
IUUC-Ame-010963	Astyanax mexicanus	69.86	0.00e+00	1249.00
IUUC-Bgr-011973	Blumeria graminis	29.05	8.00e-101	361.00
IUUC-Bta-012462	Bos taurus	72.33	0.00e+00	1272.00
IUUC-Bci-013940	Botrytis cinerea	29.70	6.00e-105	375.00
IUUC-Bdi-014725	Brachypodium distachyon	35.27	3.00e-147	515.00
IUUC-Bol-016534	Brassica oleracea	35.59	9.00e-151	527.00
IUUC-Bra-016781	Brassica rapa	35.08	2.00e-148	520.00
IUUC-Cel-018581	Caenorhabditis elegans	28.34	2.00e-93	337.00
IUUC-Cja-019675	Callithrix jacchus	72.75	0.00e+00	1312.00
IUUC-Cfa-020118	Canis familiaris	72.17	0.00e+00	1271.00
IUUC-Cpo-021798	Cavia porcellus	71.92	0.00e+00	1264.00
IUUC-Cre-022566	Chlamydomonas reinhardtii	27.97	4.00e-25	109.00
IUUC-Csa-023547	Chlorocebus sabaeus	72.77	0.00e+00	1290.00
IUUC-Cho-024518	Choloepus hoffmanni	62.57	0.00e+00	979.00
IUUC-Cin-025339	Ciona intestinalis	47.91	0.00e+00	823.00
IUUC-Cgl-026476	Colletotrichum gloeosporioides	28.40	2.00e-105	377.00
IUUC-Cne-026859	Cryptococcus neoformans	33.96	1.00e-142	500.00
IUUC-Cme-027173	Cyanidioschyzon merolae	28.56	7.00e-81	295.00
IUUC-Dre-027733	Danio rerio	69.45	0.00e+00	1253.00
IUUC-Dno-029439	Dasypus novemcinctus	72.20	0.00e+00	1270.00
IUUC-Dor-030329	Dipodomys ordii	73.89	0.00e+00	666.00
IUUC-Dse-031511	Dothistroma septosporum	28.60	7.00e-96	345.00
IUUC-Dme-031694	Drosophila melanogaster	42.48	0.00e+00	711.00
IUUC-Ete-032930	Echinops telfairi	61.88	0.00e+00	1095.00
IUUC-Eca-033302	Equus caballus	72.53	0.00e+00	1293.00
IUUC-Eeu-034516	Erinaceus europaeus	72.20	0.00e+00	1333.00
IUUC-Fca-036064	Felis catus	72.68	0.00e+00	1278.00
IUUC-Fal-037024	Ficedula albicollis	79.66	0.00e+00	1427.00
IUUC-Fox-037787	Fusarium oxysporum	27.32	1.00e-88	321.00
IUUC-Fso-038378	Fusarium solani	28.25	2.00e-92	333.00
IUUC-Gmo-039637	Gadus morhua	52.47	4.00e-154	538.00
IUUC-Ggr-040108	Gaeumannomyces graminis	28.85	2.00e-97	350.00
IUUC-Gga-040982	Gallus gallus	79.82	0.00e+00	1437.00
IUUC-Gac-041565	Gasterosteus aculeatus	58.47	0.00e+00	1010.00
IUUC-Gma-043185	Glycine max	35.69	4.00e-152	531.00
IUUC-Ggo-045463	Gorilla gorilla	72.92	0.00e+00	1310.00
IUUC-Hsa-045675	Homo sapiens	72.75	0.00e+00	1311.00
IUUC-Hvu-047352	Hordeum vulgare	34.75	1.00e-130	460.00
IUUC-Itr-048088	Ictidomys tridecemlineatus	72.87	0.00e+00	1326.00
IUUC-Kpa-049164	Komagataella pastoris	30.15	6.00e-100	358.00
IUUC-Lch-050476	Latimeria chalumnae	74.83	0.00e+00	1370.00
IUUC-Lpe-051556	Leersia perrieri	33.02	1.00e-92	333.00
IUUC-Loc-052820	Lepisosteus oculatus	73.06	0.00e+00	1320.00
IUUC-Lma-052961	Leptosphaeria maculans	29.39	1.00e-91	331.00
IUUC-Laf-054006	Loxodonta africana	70.90	0.00e+00	1252.00
IUUC-Mcc-055037	Macaca mulatta	72.75	0.00e+00	1309.00
IUUC-Mor-057280	Magnaporthe oryzae	28.07	4.00e-98	352.00
IUUC-Mpo-057408	Magnaporthe poae	28.64	9.00e-95	341.00
IUUC-Mtr-058473	Medicago truncatula	35.56	8.00e-153	534.00
IUUC-Mla-058892	Melampsora laricipopulina	35.10	2.00e-120	426.00
IUUC-Mga-059598	Meleagris gallopavo	67.48	0.00e+00	1093.00
IUUC-Mvi-060334	Microbotryum violaceum	34.53	3.00e-117	416.00
IUUC-Mmr-061239	Microcebus murinus	72.07	0.00e+00	1279.00
IUUC-Mdo-062471	Monodelphis domestica	70.97	0.00e+00	1248.00
IUUC-Mmu-063872	Mus musculus	70.52	0.00e+00	1304.00
IUUC-Mac-064631	Musa acuminata	34.24	8.00e-133	468.00
IUUC-Mpu-066039	Mustela putorius furo	72.42	0.00e+00	1306.00
IUUC-Mlu-067485	Myotis lucifugus	72.74	0.00e+00	1301.00
IUUC-Nfi-068319	Neosartorya fischeri	27.71	1.00e-89	324.00
IUUC-Ncr-068725	Neurospora crassa	28.88	6.00e-97	348.00
IUUC-Nle-069050	Nomascus leucogenys	72.75	0.00e+00	1313.00
IUUC-Opr-070437	Ochotona princeps	63.85	2.00e-105	376.00
IUUC-Ont-071574	Oreochromis niloticus	60.36	0.00e+00	1079.00
IUUC-Oan-072826	Ornithorhynchus anatinus	71.36	0.00e+00	1265.00
IUUC-Ocu-073995	Oryctolagus cuniculus	72.20	0.00e+00	1253.00
IUUC-Oba-075407	Oryza barthii	32.75	4.00e-121	428.00
IUUC-Obr-076451	Oryza brachyantha	36.07	8.00e-154	537.00
IUUC-Ogl-077535	Oryza glaberrima	35.51	1.00e-148	520.00
IUUC-Ogu-077995	Oryza glumaepatula	32.51	4.00e-119	422.00
IUUC-Oin-079431	Oryza indica	35.88	1.00e-150	526.00
IUUC-Olo-080495	Oryza longistaminata	32.93	1.00e-116	414.00
IUUC-Oni-082336	Oryza nivara	34.61	1.00e-137	484.00
IUUC-Opu-084028	Oryza punctata	34.39	3.00e-128	452.00
IUUC-Oru-084500	Oryza rufipogon	32.44	1.00e-118	420.00
IUUC-Osa-086242	Oryza sativa	35.77	1.00e-150	526.00
IUUC-Ola-086612	Oryzias latipes	56.36	0.00e+00	814.00
IUUC-Olu-087703	Ostreococcus lucimarinus	28.96	9.00e-105	374.00
IUUC-Oga-088572	Otolemur garnettii	72.58	0.00e+00	1290.00
IUUC-Oar-090363	Ovis aries	71.73	0.00e+00	1293.00
IUUC-Ptr-090477	Pan troglodytes	72.97	0.00e+00	1295.00
IUUC-Pan-092914	Papio anubis	72.86	0.00e+00	1313.00
IUUC-Psi-093019	Pelodiscus sinensis	81.34	0.00e+00	1474.00
IUUC-Pma-094303	Petromyzon marinus	52.12	0.00e+00	828.00
IUUC-Pno-094938	Phaeosphaeria nodorum	29.13	3.00e-87	316.00
IUUC-Ppa-095720	Physcomitrella patens	34.85	2.00e-149	523.00
IUUC-Pfo-097034	Poecilia formosa	59.21	0.00e+00	1026.00
IUUC-Pab-097669	Pongo abelii	72.86	0.00e+00	1312.00
IUUC-Pop-098835	Populus trichocarpa	36.31	6.00e-151	528.00
IUUC-Pca-101097	Procavia capensis	68.91	9.00e-137	481.00
IUUC-Ppe-101430	Prunus persica	35.27	1.00e-152	533.00
IUUC-Pva-103152	Pteropus vampyrus	72.90	0.00e+00	1330.00
IUUC-Pgr-103517	Puccinia graminis	32.31	5.00e-127	448.00
IUUC-Ptt-103697	Puccinia triticina	33.03	3.00e-100	359.00
IUUC-Pte-104121	Pyrenophora teres	29.22	2.00e-91	330.00
IUUC-Pyt-104672	Pyrenophora triticirepentis	29.14	8.00e-94	338.00
IUUC-Rno-105435	Rattus norvegicus	70.74	0.00e+00	1278.00
IUUC-Sce-106202	Saccharomyces cerevisiae	28.97	2.00e-100	360.00
IUUC-Sha-107272	Sarcophilus harrisii	71.55	0.00e+00	1193.00
IUUC-Sja-107744	Schizosaccharomyces japonicus	35.82	5.00e-152	531.00
IUUC-Spo-108256	Schizosaccharomyces pombe	35.39	6.00e-149	521.00
IUUC-Ssl-108618	Sclerotinia sclerotiorum	28.78	2.00e-103	370.00
IUUC-Smo-108762	Selaginella moellendorffii	35.34	2.00e-149	523.00
IUUC-Sit-110051	Setaria italica	35.46	3.00e-147	515.00
IUUC-Sly-111181	Solanum lycopersicum	35.51	2.00e-153	536.00
IUUC-Stu-112018	Solanum tuberosum	35.80	1.00e-152	533.00
IUUC-Sar-113348	Sorex araneus	71.56	0.00e+00	922.00
IUUC-Sbi-114282	Sorghum bicolor	35.09	1.00e-146	513.00
IUUC-Sre-114946	Sporisorium reilianum	32.17	8.00e-94	338.00
IUUC-Ssc-115287	Sus scrofa	72.70	0.00e+00	1317.00
IUUC-Tgu-117138	Taeniopygia guttata	74.82	0.00e+00	1174.00
IUUC-Tru-118232	Takifugu rubripes	59.61	0.00e+00	1043.00
IUUC-Tsy-119502	Tarsius syrichta	60.36	0.00e+00	1027.00
IUUC-Tni-120378	Tetraodon nigroviridis	58.11	0.00e+00	1016.00
IUUC-Tca-121506	Theobroma cacao	35.78	6.00e-148	518.00
IUUC-Tre-122166	Trichoderma reesei	28.45	2.00e-98	353.00
IUUC-Tvi-122385	Trichoderma virens	28.28	1.00e-99	358.00
IUUC-Tae-122836	Triticum aestivum	35.10	2.00e-148	519.00
IUUC-Tur-126490	Triticum urartu	31.79	6.00e-112	398.00
IUUC-Tme-127157	Tuber melanosporum	32.04	2.00e-104	373.00
IUUC-Tbe-127981	Tupaia belangeri	66.31	0.00e+00	1113.00
IUUC-Ttr-128886	Tursiops truncatus	71.22	0.00e+00	1276.00
IUUC-Uma-129439	Ustilago maydis	31.63	6.00e-100	358.00
IUUC-Vda-129760	Verticillium dahliae	28.31	1.00e-94	340.00
IUUC-Vpa-130456	Vicugna pacos	71.86	0.00e+00	1294.00
IUUC-Vvi-131086	Vitis vinifera	34.03	5.00e-143	501.00
IUUC-Xtr-131829	Xenopus tropicalis	71.60	0.00e+00	1290.00
IUUC-Xma-133588	Xiphophorus maculatus	59.21	0.00e+00	1012.00
IUUC-Yli-134328	Yarrowia lipolytica	30.51	7.00e-106	378.00
IUUC-Zma-135808	Zea mays	34.82	4.00e-147	515.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence