iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007547

UUCD1 version

UUC-ArT-01590

Ensembl Protein ID

AT2G02760.1

UniProt Accession

P42745; Q4TZ07; UBC2_ARATH

Genbank Protein ID

AAA32899.1; CAA73476.1; AAY44843.1; AAC05346.1; AEC05621.1; ANM63049.1; ANM63050.1; ANM63051.1; AAK48985.1; AAL66894.1

Protein Name

Ubiquitin-conjugating enzyme E2 2; E2 ubiquitin-conjugating enzyme 2; Ubiquitin carrier protein 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; Ubiquitin-protein ligase 2

Genbank Nucleotide ID

L19353; Y13031; DQ027017; AC002521; CP002685; CP002685; CP002685; CP002685; AF370558; AY072479

Gene Name

UBC2; At2g02760; T20F6.10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G02760	AT2G02760.1	AT2G02760.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
iRefIndex	PINA	HINT
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	8219072; 16339806

Classification

Family	E-value	Score	Start	End
E2/UBC	3.90e-53	179.8	8	143

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           Rl++++k+l++dpp+gis  p+d+ +++ w+++i+Gp+dtp++gg+Fkl+++f+edYP kPP+v+f++++fhPn+y++G++Cl+il+  ++Wsp ++v
   Q: 8    RLMRDFKRLQQDPPAGISGAPQDN-NIMLWNAVIFGPDDTPWDGGTFKLSLQFSEDYPNKPPTVRFVSRMFHPNIYADGSICLDILQ--NQWSPIYDV 102
           9**********************9.9************************************************************9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           + +l+siqsll++pnp+sp+n+eaa++++++++ey+++vre
   Q: 103  AAILTSIQSLLCDPNPNSPANSEAARMFSESKREYNRRVRE 143
           **************************************985 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MSTPARKRLM RDFKRLQQDP PAGISGAPQD NNIMLWNAVI FGPDDTPWDG GTFKLSLQFS 60
EDYPNKPPTV RFVSRMFHPN IYADGSICLD ILQNQWSPIY DVAAILTSIQ SLLCDPNPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGAACAAA AAAATATCTG AAGTCTCTCT GACTGTACAC AGAGAGAGAG ATAAATAGAT 60
ATGTGTTGAT TAGATCGAAG CTTCTAGAAG ATCACACCAC TGCGTGCGTT ATACGAACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006281--P:DNA repair
GO:0033523--P:histone H2B ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0010228--P:vegetative to reproductive phase transition of meristem

KEGG

ath:AT2G02760

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001001	Aegilops tauschii	93.42	7.00e-85	305.00
IUUC-Atr-002623	Amborella trichopoda	97.37	1.00e-86	310.00
IUUC-Aly-006336	Arabidopsis lyrata	100.00	1.00e-79	287.00
IUUC-Ago-007745	Ashbya gossypii	65.10	7.00e-60	221.00
IUUC-Acl-008139	Aspergillus clavatus	65.77	3.00e-60	223.00
IUUC-Bgr-012039	Blumeria graminis	64.93	4.00e-54	202.00
IUUC-Bci-013919	Botrytis cinerea	67.11	7.00e-62	228.00
IUUC-Bdi-014308	Brachypodium distachyon	95.39	5.00e-86	308.00
IUUC-Cre-022822	Chlamydomonas reinhardtii	77.63	7.00e-62	228.00
IUUC-Cne-026864	Cryptococcus neoformans	67.79	4.00e-61	226.00
IUUC-Dse-031487	Dothistroma septosporum	65.77	8.00e-61	224.00
IUUC-Fso-038232	Fusarium solani	66.44	3.00e-61	226.00
IUUC-Gma-043883	Glycine max	97.37	2.00e-87	313.00
IUUC-Hvu-047054	Hordeum vulgare	93.42	7.00e-85	305.00
IUUC-Lpe-051301	Leersia perrieri	95.39	3.00e-86	309.00
IUUC-Mpo-057498	Magnaporthe poae	65.13	2.00e-61	227.00
IUUC-Mtr-058305	Medicago truncatula	97.37	1.00e-87	314.00
IUUC-Mvi-060330	Microbotryum violaceum	70.39	2.00e-55	207.00
IUUC-Mac-065428	Musa acuminata	95.39	1.00e-86	311.00
IUUC-Ncr-068913	Neurospora crassa	65.77	4.00e-61	226.00
IUUC-Oba-075847	Oryza barthii	95.39	1.00e-85	308.00
IUUC-Obr-076713	Oryza brachyantha	95.39	3.00e-86	309.00
IUUC-Ogl-076956	Oryza glaberrima	95.39	5.00e-86	308.00
IUUC-Ogu-078696	Oryza glumaepatula	95.39	3.00e-86	309.00
IUUC-Oin-080106	Oryza indica	95.39	5.00e-86	308.00
IUUC-Olo-081018	Oryza longistaminata	81.21	1.00e-73	268.00
IUUC-Ome-081285	Oryza meridionalis	95.39	3.00e-86	309.00
IUUC-Oni-082088	Oryza nivara	95.39	3.00e-86	309.00
IUUC-Opu-083310	Oryza punctata	95.39	3.00e-86	309.00
IUUC-Oru-084449	Oryza rufipogon	95.39	3.00e-86	309.00
IUUC-Osa-086191	Oryza sativa	95.39	5.00e-86	308.00
IUUC-Pno-094935	Phaeosphaeria nodorum	65.77	5.00e-61	225.00
IUUC-Pop-099712	Populus trichocarpa	98.03	5.00e-79	285.00
IUUC-Ppe-101949	Prunus persica	97.37	6.00e-87	312.00
IUUC-Sce-106283	Saccharomyces cerevisiae	65.10	6.00e-60	222.00
IUUC-Ssl-108432	Sclerotinia sclerotiorum	67.11	7.00e-62	228.00
IUUC-Sit-110731	Setaria italica	95.39	3.00e-86	309.00
IUUC-Sly-111506	Solanum lycopersicum	98.03	2.00e-87	313.00
IUUC-Stu-112518	Solanum tuberosum	96.71	3.00e-87	313.00
IUUC-Sbi-114870	Sorghum bicolor	96.71	9.00e-87	311.00
IUUC-Tca-121827	Theobroma cacao	96.71	4.00e-87	312.00
IUUC-Tur-126866	Triticum urartu	94.74	8.00e-86	308.00
IUUC-Tme-127148	Tuber melanosporum	67.79	1.00e-61	228.00
IUUC-Vvi-131547	Vitis vinifera	97.37	1.00e-87	314.00
IUUC-Zma-135584	Zea mays	96.05	8.00e-86	308.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence