iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072170

Ensembl Protein ID

ENSONIP00000008533.1

UniProt Accession

I3JI39; I3JI39_ORENI

Genbank Protein ID

ENSONIP00000008533

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AERX01026724

Gene Name

uchl3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000006758.1	ENSONIT00000008538.1	ENSONIP00000008533.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	5.70e-65	220.3	4	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           ++wl+Les+P+++t++v+ +g+k  +q+ ++y+Ldpe l+++++pv+++lllF+++ek+e+++  q++ ++l+ + +++   ++f+kq+
   Q: 4    PRWLPLESNPEVMTKFVSCLGMKPTWQFGDVYGLDPELLSMVPRPVCAVLLLFPVTEKYEAFK--QEEEEKLKDQPQEVSPDVYFIKQT 90
           89************************************************************9..6667899***************** PP
   S: 95   igNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvs 182
           igN+C+t++l+++++n++ +l ++  + l++++e+t ++ pe++a  l++++ ++++h+s a+++++++p+ +       +k ++hf++
   Q: 91   IGNACGTIGLIHAVANNQAHLeFEPDSPLKKFLEQTSKMTPEERATFLEKDESIRVTHESSAQEGQTEAPSLD-------EKVNLHFIA 172
           **********************************************************************777.......889****** PP
   S: 183  yvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           +vn++g+lyeldg+kpfP+ +gk++e++ l+d+++v++ f+ r    + +e+rf+++a+++d
   Q: 173  FVNVGGHLYELDGRKPFPIAHGKTSEDTFLEDAVEVCKVFMAR----DPQEVRFTIIALSKD 230
           *******************************************....9***********998 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MDSPRWLPLE SNPEVMTKFV SCLGMKPTWQ FGDVYGLDPE LLSMVPRPVC AVLLLFPVTE 60
KYEAFKQEEE EKLKDQPQEV SPDVYFIKQT IGNACGTIGL IHAVANNQAH LEFEPDSPLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAATGCATC CATATATGTC ACATGCCTTA TCAAGTCTTT TGGGCATGTT CTTTGGGTAG 60
TTATGGTTTA TTGATAAAGG CAAGTCACCC CCGCGGATCA CATACATGTC AACGTGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007219--P:Notch signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	43.40	1.00e-52	199.00
IUUC-Aml-001344	Ailuropoda melanoleuca	70.61	1.00e-97	349.00
IUUC-Atr-002931	Amborella trichopoda	48.28	1.00e-48	186.00
IUUC-Apl-003949	Anas platyrhynchos	71.83	1.00e-84	305.00
IUUC-Aca-004924	Anolis carolinensis	72.05	2.00e-97	348.00
IUUC-Aly-005939	Arabidopsis lyrata	46.49	4.00e-55	207.00
IUUC-Ath-006827	Arabidopsis thaliana	47.37	2.00e-56	211.00
IUUC-Ago-007950	Ashbya gossypii	35.65	2.00e-30	125.00
IUUC-Acl-008305	Aspergillus clavatus	38.77	9.00e-37	147.00
IUUC-Afl-008611	Aspergillus flavus	41.20	1.00e-44	173.00
IUUC-Afu-008945	Aspergillus fumigatus	39.66	2.00e-40	158.00
IUUC-Ani-009339	Aspergillus nidulans	38.98	3.00e-41	162.00
IUUC-Ang-009691	Aspergillus niger	38.72	8.00e-42	163.00
IUUC-Aor-009961	Aspergillus oryzae	41.20	2.00e-44	172.00
IUUC-Ate-010316	Aspergillus terreus	39.06	1.00e-41	162.00
IUUC-Ame-011157	Astyanax mexicanus	82.53	1.00e-114	405.00
IUUC-Bgr-012125	Blumeria graminis	36.25	3.00e-38	151.00
IUUC-Bta-012673	Bos taurus	70.18	9.00e-98	349.00
IUUC-Bci-013734	Botrytis cinerea	38.79	2.00e-42	166.00
IUUC-Bdi-014330	Brachypodium distachyon	46.02	2.00e-55	209.00
IUUC-Bol-015214	Brassica oleracea	47.37	4.00e-57	214.00
IUUC-Bra-017491	Brassica rapa	46.93	3.00e-56	211.00
IUUC-Cel-018236	Caenorhabditis elegans	30.04	8.00e-22	97.40
IUUC-Cfa-020371	Canis familiaris	71.66	3.00e-79	287.00
IUUC-Cpo-022036	Cavia porcellus	69.74	6.00e-96	343.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	42.79	2.00e-35	141.00
IUUC-Csa-023854	Chlorocebus sabaeus	70.18	2.00e-96	345.00
IUUC-Cho-024548	Choloepus hoffmanni	61.54	2.00e-20	92.00
IUUC-Cin-025545	Ciona intestinalis	53.54	3.00e-68	251.00
IUUC-Cgl-026409	Colletotrichum gloeosporioides	36.21	1.00e-33	136.00
IUUC-Cne-026914	Cryptococcus neoformans	34.89	1.00e-29	123.00
IUUC-Cme-027216	Cyanidioschyzon merolae	37.71	1.00e-27	116.00
IUUC-Dre-028356	Danio rerio	80.35	3.00e-111	394.00
IUUC-Dse-031461	Dothistroma septosporum	39.08	4.00e-36	144.00
IUUC-Dme-032146	Drosophila melanogaster	54.02	4.00e-66	244.00
IUUC-Eca-033220	Equus caballus	70.61	6.00e-97	346.00
IUUC-Fca-036421	Felis catus	70.61	1.00e-97	349.00
IUUC-Fal-036773	Ficedula albicollis	71.63	6.00e-85	306.00
IUUC-Fox-037830	Fusarium oxysporum	36.91	3.00e-38	152.00
IUUC-Fso-038259	Fusarium solani	34.62	7.00e-35	142.00
IUUC-Gmo-039468	Gadus morhua	76.86	3.00e-96	344.00
IUUC-Ggr-039832	Gaeumannomyces graminis	37.83	4.00e-37	147.00
IUUC-Gga-041205	Gallus gallus	71.49	4.00e-91	327.00
IUUC-Gac-041629	Gasterosteus aculeatus	93.04	2.00e-119	421.00
IUUC-Gma-043057	Glycine max	46.52	4.00e-50	191.00
IUUC-Ggo-044533	Gorilla gorilla	70.31	2.00e-96	344.00
IUUC-Hsa-046754	Homo sapiens	70.61	1.00e-97	349.00
IUUC-Hvu-047176	Hordeum vulgare	41.23	4.00e-43	167.00
IUUC-Kpa-049123	Komagataella pastoris	38.81	6.00e-33	134.00
IUUC-Lch-049685	Latimeria chalumnae	74.67	6.00e-104	369.00
IUUC-Lpe-051377	Leersia perrieri	45.77	9.00e-46	176.00
IUUC-Loc-051988	Lepisosteus oculatus	79.48	4.00e-110	390.00
IUUC-Lma-053316	Leptosphaeria maculans	40.87	2.00e-44	172.00
IUUC-Laf-053985	Loxodonta africana	70.74	3.00e-97	347.00
IUUC-Mcc-055888	Macaca mulatta	70.18	3.00e-95	340.00
IUUC-Mor-057271	Magnaporthe oryzae	37.77	1.00e-41	162.00
IUUC-Mpo-057343	Magnaporthe poae	31.93	1.00e-22	99.40
IUUC-Mtr-057713	Medicago truncatula	47.39	9.00e-54	203.00
IUUC-Mla-058942	Melampsora laricipopulina	46.19	5.00e-51	194.00
IUUC-Mga-059702	Meleagris gallopavo	72.51	1.00e-84	305.00
IUUC-Mvi-060249	Microbotryum violaceum	44.44	2.00e-43	169.00
IUUC-Mmr-061284	Microcebus murinus	68.35	2.00e-63	235.00
IUUC-Mdo-062639	Monodelphis domestica	62.03	4.00e-93	334.00
IUUC-Mmu-063299	Mus musculus	71.05	5.00e-98	350.00
IUUC-Mac-065075	Musa acuminata	47.16	5.00e-58	217.00
IUUC-Mpu-066769	Mustela putorius furo	70.61	1.00e-97	349.00
IUUC-Mlu-066937	Myotis lucifugus	69.30	1.00e-95	342.00
IUUC-Nfi-068320	Neosartorya fischeri	39.83	4.00e-41	161.00
IUUC-Ncr-068673	Neurospora crassa	37.02	2.00e-41	162.00
IUUC-Nle-069175	Nomascus leucogenys	70.75	3.00e-89	320.00
IUUC-Opr-070652	Ochotona princeps	69.57	2.00e-44	172.00
IUUC-Oan-073247	Ornithorhynchus anatinus	67.26	5.00e-42	162.00
IUUC-Ocu-074422	Oryctolagus cuniculus	70.61	9.00e-98	349.00
IUUC-Oba-075098	Oryza barthii	43.56	2.00e-51	195.00
IUUC-Obr-076041	Oryza brachyantha	44.93	6.00e-53	200.00
IUUC-Ogl-076980	Oryza glaberrima	45.81	2.00e-53	201.00
IUUC-Ogu-078978	Oryza glumaepatula	39.68	3.00e-48	185.00
IUUC-Oin-079285	Oryza indica	43.11	9.00e-51	193.00
IUUC-Olo-080671	Oryza longistaminata	43.56	3.00e-51	194.00
IUUC-Ome-081428	Oryza meridionalis	42.67	5.00e-50	190.00
IUUC-Oni-082406	Oryza nivara	43.56	2.00e-51	195.00
IUUC-Opu-083305	Oryza punctata	43.11	1.00e-49	189.00
IUUC-Oru-084969	Oryza rufipogon	43.56	2.00e-51	195.00
IUUC-Osa-085830	Oryza sativa	45.81	2.00e-53	201.00
IUUC-Ola-086893	Oryzias latipes	94.35	3.00e-116	410.00
IUUC-Olu-087858	Ostreococcus lucimarinus	40.53	2.00e-46	179.00
IUUC-Oga-088055	Otolemur garnettii	70.31	2.00e-96	344.00
IUUC-Oar-090319	Ovis aries	69.74	3.00e-97	347.00
IUUC-Pan-092714	Papio anubis	69.87	9.00e-96	342.00
IUUC-Psi-094036	Pelodiscus sinensis	73.02	3.00e-86	311.00
IUUC-Pma-094412	Petromyzon marinus	64.74	2.00e-53	201.00
IUUC-Pno-094997	Phaeosphaeria nodorum	36.61	2.00e-33	135.00
IUUC-Ppa-095519	Physcomitrella patens	50.66	5.00e-65	240.00
IUUC-Pfo-096182	Poecilia formosa	91.88	6.00e-119	419.00
IUUC-Pop-099282	Populus trichocarpa	44.30	3.00e-49	188.00
IUUC-Ppe-101332	Prunus persica	47.83	1.00e-56	212.00
IUUC-Pgr-103430	Puccinia graminis	48.35	2.00e-51	195.00
IUUC-Ptt-103955	Puccinia triticina	50.42	2.00e-52	198.00
IUUC-Pte-104414	Pyrenophora teres	40.34	8.00e-41	160.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	33.47	1.00e-31	130.00
IUUC-Rno-105096	Rattus norvegicus	70.61	5.00e-97	347.00
IUUC-Sce-106412	Saccharomyces cerevisiae	37.76	4.00e-31	128.00
IUUC-Sha-106677	Sarcophilus harrisii	69.43	7.00e-92	329.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	30.58	5.00e-25	107.00
IUUC-Spo-108322	Schizosaccharomyces pombe	31.46	4.00e-24	104.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	37.45	4.00e-39	154.00
IUUC-Smo-108914	Selaginella moellendorffii	47.41	2.00e-52	199.00
IUUC-Sit-110163	Setaria italica	45.45	4.00e-53	201.00
IUUC-Sly-111832	Solanum lycopersicum	48.03	2.00e-53	201.00
IUUC-Stu-112526	Solanum tuberosum	48.03	7.00e-54	203.00
IUUC-Sbi-114545	Sorghum bicolor	46.93	3.00e-53	201.00
IUUC-Sre-114961	Sporisorium reilianum	44.78	1.00e-43	169.00
IUUC-Ssc-115255	Sus scrofa	71.43	5.00e-91	326.00
IUUC-Tgu-117003	Taeniopygia guttata	71.49	6.00e-90	323.00
IUUC-Tru-118330	Takifugu rubripes	77.60	4.00e-84	306.00
IUUC-Tni-120042	Tetraodon nigroviridis	83.15	5.00e-89	322.00
IUUC-Tca-120976	Theobroma cacao	46.90	4.00e-54	204.00
IUUC-Tre-122149	Trichoderma reesei	38.46	2.00e-40	159.00
IUUC-Tvi-122450	Trichoderma virens	36.09	2.00e-38	152.00
IUUC-Tae-122693	Triticum aestivum	44.54	2.00e-52	199.00
IUUC-Tur-126250	Triticum urartu	43.40	3.00e-52	197.00
IUUC-Tme-126961	Tuber melanosporum	43.17	1.00e-35	143.00
IUUC-Tbe-128048	Tupaia belangeri	58.33	5.00e-54	203.00
IUUC-Uma-129382	Ustilago maydis	43.53	2.00e-47	182.00
IUUC-Vda-129850	Verticillium dahliae	34.58	4.00e-32	131.00
IUUC-Vpa-130783	Vicugna pacos	69.57	8.00e-45	173.00
IUUC-Vvi-131661	Vitis vinifera	44.93	9.00e-54	203.00
IUUC-Xtr-132428	Xenopus tropicalis	69.87	2.00e-98	351.00
IUUC-Xma-134245	Xiphophorus maculatus	90.87	2.00e-116	411.00
IUUC-Yli-134570	Yarrowia lipolytica	36.75	1.00e-35	142.00
IUUC-Zma-134740	Zea mays	44.74	2.00e-53	201.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence