iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pno-095015

Ensembl Protein ID

SNOT_14035

UniProt Accession

Q0U2J8; ATG18_PHANO

Genbank Protein ID

EAT78660.2

Protein Name

Autophagy-related protein 18

Genbank Nucleotide ID

CH445353

Gene Name

ATG18; SNOG_14035

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SNOG_14035	SNOT_14035	SNOT_14035

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-07	29.8	186	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgt.ikvWDlrt 32
           H+++ +c+a+ +d tll+++s  gt i+v+++ +
   Q: 186  HNSPLSCIALnNDgTLLATASEKGTiIRVFSIPD 219
           9**********999***********999998655 PP

Organism

Phaeosphaeria nodorum

Functional Description
(View)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

Protein Sequence
(Fasta)

MNFVTFNQDH SHLGVGTSNG YRVYTTDPFN KQSESREGDV SSLEMLFSTS LVALTLSPRV 60
LRIQNTKGKR HSTICEMTFR TAILAMRLNR KRLVVVLESE LYIYDISNMQ MLRTEKTSPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACTTCG TGACGTTCAA CCAGGACCAC AGCCACCTCG GCGTGGGTAT GTAGCAGCTC 60
CATCCGCCAG GTAGCGAGTT CTAACACGGC GCATAGGTAC CAGCAACGGC TATCGGGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0010008--C:endosome membrane
GO:0000329--C:fungal-type vacuole membrane
GO:0005794--C:Golgi apparatus
GO:0034045--C:pre-autophagosomal structure membrane
GO:0016236--P:macroautophagy
GO:0015031--P:protein transport

KEGG

pno:SNOG_14035

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001842	Ailuropoda melanoleuca	42.02	2.00e-47	181.00
IUUC-Apl-003390	Anas platyrhynchos	41.63	3.00e-47	180.00
IUUC-Aca-004975	Anolis carolinensis	41.95	1.00e-50	192.00
IUUC-Ago-007948	Ashbya gossypii	48.34	2.00e-37	148.00
IUUC-Acl-008148	Aspergillus clavatus	61.81	9.00e-143	498.00
IUUC-Afl-008562	Aspergillus flavus	61.00	1.00e-141	494.00
IUUC-Afu-008936	Aspergillus fumigatus	61.36	4.00e-144	502.00
IUUC-Ani-009254	Aspergillus nidulans	61.34	1.00e-146	511.00
IUUC-Ang-009798	Aspergillus niger	60.90	9.00e-145	504.00
IUUC-Aor-010066	Aspergillus oryzae	61.00	1.00e-141	494.00
IUUC-Ate-010266	Aspergillus terreus	63.33	2.00e-150	523.00
IUUC-Ame-010727	Astyanax mexicanus	42.70	6.00e-52	196.00
IUUC-Bta-012655	Bos taurus	41.95	2.00e-50	191.00
IUUC-Bci-013627	Botrytis cinerea	57.79	9.00e-122	428.00
IUUC-Cel-018503	Caenorhabditis elegans	28.77	7.00e-40	156.00
IUUC-Cja-018829	Callithrix jacchus	39.58	4.00e-45	173.00
IUUC-Cfa-020858	Canis familiaris	39.10	2.00e-47	181.00
IUUC-Cpo-022235	Cavia porcellus	41.89	6.00e-50	189.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	36.23	9.00e-40	155.00
IUUC-Csa-023963	Chlorocebus sabaeus	38.87	5.00e-46	176.00
IUUC-Cho-024328	Choloepus hoffmanni	44.49	9.00e-45	172.00
IUUC-Cin-025343	Ciona intestinalis	35.45	2.00e-52	197.00
IUUC-Csv-025920	Ciona savignyi	33.57	6.00e-57	212.00
IUUC-Cgl-026425	Colletotrichum gloeosporioides	64.71	4.00e-49	186.00
IUUC-Cne-026947	Cryptococcus neoformans	47.61	4.00e-88	316.00
IUUC-Dre-027490	Danio rerio	34.92	5.00e-56	209.00
IUUC-Dno-030057	Dasypus novemcinctus	41.63	2.00e-47	181.00
IUUC-Dor-030472	Dipodomys ordii	43.56	2.00e-43	168.00
IUUC-Dse-031215	Dothistroma septosporum	52.58	2.00e-120	423.00
IUUC-Ete-032276	Echinops telfairi	31.97	5.00e-42	163.00
IUUC-Eca-034362	Equus caballus	34.31	4.00e-54	203.00
IUUC-Fca-036230	Felis catus	41.80	9.00e-47	179.00
IUUC-Fal-036782	Ficedula albicollis	41.63	6.00e-47	179.00
IUUC-Fox-037797	Fusarium oxysporum	53.93	2.00e-114	404.00
IUUC-Fso-038174	Fusarium solani	54.79	8.00e-117	411.00
IUUC-Gmo-039706	Gadus morhua	33.09	1.00e-51	195.00
IUUC-Ggr-040113	Gaeumannomyces graminis	50.64	2.00e-121	427.00
IUUC-Gga-040690	Gallus gallus	41.95	8.00e-51	192.00
IUUC-Gac-042454	Gasterosteus aculeatus	33.81	5.00e-54	203.00
IUUC-Gma-043876	Glycine max	37.45	1.00e-43	168.00
IUUC-Hsa-046782	Homo sapiens	39.22	9.00e-47	179.00
IUUC-Itr-048693	Ictidomys tridecemlineatus	39.22	9.00e-47	179.00
IUUC-Kpa-049378	Komagataella pastoris	44.88	1.00e-62	232.00
IUUC-Lch-050126	Latimeria chalumnae	33.91	2.00e-49	187.00
IUUC-Lma-052948	Leptosphaeria maculans	87.44	0.00e+00	711.00
IUUC-Laf-054007	Loxodonta africana	41.95	9.00e-51	192.00
IUUC-Meu-056020	Macropus eugenii	32.03	2.00e-28	117.00
IUUC-Mor-057125	Magnaporthe oryzae	54.44	8.00e-125	438.00
IUUC-Mga-059795	Meleagris gallopavo	41.63	3.00e-47	180.00
IUUC-Mvi-060219	Microbotryum violaceum	47.38	2.00e-88	317.00
IUUC-Mmr-061096	Microcebus murinus	32.73	7.00e-53	199.00
IUUC-Mdo-062881	Monodelphis domestica	41.57	4.00e-50	189.00
IUUC-Mmu-063787	Mus musculus	34.20	5.00e-57	213.00
IUUC-Mac-064838	Musa acuminata	32.96	1.00e-37	149.00
IUUC-Mpu-066019	Mustela putorius furo	40.07	2.00e-48	184.00
IUUC-Mlu-068016	Myotis lucifugus	41.95	2.00e-50	191.00
IUUC-Nfi-068424	Neosartorya fischeri	62.47	9.00e-146	508.00
IUUC-Ncr-068833	Neurospora crassa	53.54	4.00e-123	432.00
IUUC-Opr-070933	Ochotona princeps	44.71	2.00e-32	131.00
IUUC-Ont-072495	Oreochromis niloticus	43.07	7.00e-52	196.00
IUUC-Oan-073084	Ornithorhynchus anatinus	44.05	2.00e-44	171.00
IUUC-Ocu-074689	Oryctolagus cuniculus	41.51	2.00e-49	188.00
IUUC-Oba-075601	Oryza barthii	36.10	4.00e-34	136.00
IUUC-Ogu-078089	Oryza glumaepatula	35.74	8.00e-34	135.00
IUUC-Oin-079071	Oryza indica	35.74	1.00e-33	135.00
IUUC-Oni-083063	Oryza nivara	35.74	9.00e-34	135.00
IUUC-Oru-084845	Oryza rufipogon	35.74	9.00e-34	135.00
IUUC-Osa-086113	Oryza sativa	35.74	9.00e-34	135.00
IUUC-Oga-088894	Otolemur garnettii	39.22	9.00e-47	179.00
IUUC-Oar-089850	Ovis aries	41.63	2.00e-47	181.00
IUUC-Ptr-090456	Pan troglodytes	39.22	9.00e-47	179.00
IUUC-Pan-092249	Papio anubis	41.89	2.00e-49	187.00
IUUC-Psi-094095	Pelodiscus sinensis	41.63	3.00e-47	180.00
IUUC-Pfo-096987	Poecilia formosa	42.70	5.00e-52	196.00
IUUC-Pab-097754	Pongo abelii	41.57	3.00e-46	177.00
IUUC-Pva-103047	Pteropus vampyrus	41.63	4.00e-47	180.00
IUUC-Pte-104139	Pyrenophora teres	89.86	0.00e+00	719.00
IUUC-Pyt-104488	Pyrenophora triticirepentis	89.86	0.00e+00	719.00
IUUC-Rno-105990	Rattus norvegicus	34.44	2.00e-57	214.00
IUUC-Sce-106327	Saccharomyces cerevisiae	34.94	4.00e-68	250.00
IUUC-Sha-106581	Sarcophilus harrisii	41.63	4.00e-47	180.00
IUUC-Sja-107913	Schizosaccharomyces japonicus	39.76	2.00e-72	264.00
IUUC-Spo-108068	Schizosaccharomyces pombe	39.46	5.00e-68	249.00
IUUC-Ssl-108418	Sclerotinia sclerotiorum	57.76	5.00e-133	465.00
IUUC-Sre-115219	Sporisorium reilianum	48.04	4.00e-91	326.00
IUUC-Ssc-116360	Sus scrofa	42.70	7.00e-51	192.00
IUUC-Tgu-116951	Taeniopygia guttata	41.63	3.00e-47	180.00
IUUC-Tru-118107	Takifugu rubripes	40.68	9.00e-42	162.00
IUUC-Tre-121895	Trichoderma reesei	53.30	2.00e-123	434.00
IUUC-Tvi-122311	Trichoderma virens	53.06	5.00e-124	436.00
IUUC-Uma-129438	Ustilago maydis	48.83	5.00e-81	292.00
IUUC-Vda-129782	Verticillium dahliae	52.04	3.00e-91	326.00
IUUC-Xma-133370	Xiphophorus maculatus	42.70	5.00e-52	196.00
IUUC-Yli-134337	Yarrowia lipolytica	48.11	6.00e-95	338.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence